Clinical trials: Laparoscopic Colectomy
Pain, Postoperative, Acute Pain
EFFECT - EFFectiveness of ESPB (Erector Spinae Plane Block) in Laparoscopic Cοlectomies Trial
The aim of the trial is to study the efficacy of continuous bilateral Erector Spinae Plane Block (ESPB) in managing perioperative pain in patients who undergo elective laparoscopic colectomy.
- Conditions
- Pain, Postoperative, Acute Pain, Postoperative Complications, Pain
- Trial name
- EFFECT (NCT04879004)
- Testing
- Ropivacaine injection
- Where
- Greece
- Volunteers
- 40 people
- Sponsor
- Democritus University of Thrace
Colonic Neoplasms
Double Blinded Randomized Clinical Trial of the Effect of Open Versus Laparoscopic Colectomy on Neutrophils in Patients With Colon Cancer
The purpose of this study is: to determine neutrophil activity in patients with colon cancer, to determine levels sFas, sFasL and IL - 17 in serum of healthy volunteers and colon cancer patients and establish its prognostic…
- Trial name
- NCT00860691
- Testing
- Therapeutic conventional colorectal surgery, Therapeutic laparoscopic colorectal surgery, Peripheral blood sampling and performing: ELISA test of sFas, sFasL, IL - 17 and Bursttest
- Where
- Croatia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital Dubrava
Colorectal Neoplasms, Benign
Full-thickness Laparo-endoscopic Excision vs Laparoscopic Colectomy for Colonic Tumors
Adenoma - carcinoma is a classic pathway of carcinogenesis. On this basis, timely removal of colon adenomas is a prophylactic measure to prevent colon cancer.
- Trial name
- FlexLaC (NCT04801355)
- Testing
- full-thickness laparo-endoscopic colon adenomas excision, laparoscopic colon resection
- Where
- Russia
- Volunteers
- 100 people
- Sponsor
- State Scientific Centre of Coloproctology, Russian Federation
Colorectal Cancer, Anastomotic Complication
Minimally Invasive Right Colectomy Anastomosis Study
Right colectomy (hemicolectomy) involves the removal of the cecum, the ascending colon, the hepatic flexure, the first one-third of the transverse colon, part of the terminal ileum, and the associated regional fat and lymph…
- Conditions
- Colorectal Cancer, Anastomotic Complication, Colectomy
- Trial name
- MIRCAST (NCT03650517)
- Testing
- Extracorporeal Anastomosis, Intracorporeal Anastomosis, Robotic Surgery
- Where
- 32 sites in Croatia, Denmark and 8 more
- Volunteers
- 1,200 people
- Sponsor
- Instituto de Investigación Marqués de Valdecilla
Colon Cancer
Laparoscopic Versus Open Right Colectomy for Right Colon Cancer
The purpose of this research protocol is to compare open versus laparoscopic right colectomy (according to the CME technique of complete mesocolic excision) for right colon cancer.
- Trial name
- NCT05713903
- Testing
- Laparoscopic right colectomy, Open right colectomy
- Where
- Greece
- Volunteers
- 114 people
- Sponsor
- Larissa University Hospital
Colorectal Cancer
Evaluation of Short-term Outcomes of Day Surgery for Patients With CuRC
To evaluate the feasibility and safety of laparoscopic colectomy and anterior resection for patients with colon/upper rectal cancer (CuRC) in day surgery center.
- Trial name
- NCT04646915
- Testing
- Day surgery
- Where
- China
- Volunteers
- 120 people
- Sponsor
- West China Hospital
Colon Cancer
Evaluation of NiTi Laparoscopic Compression Anastomosis Clip (LapCAC) Device for Intra-Corporeal Lap-Colectomy
The study involves adult subject requiring colonic anastomosis following laparoscopic intra-corporeal surgery. The anastomosis will be performed by using nitinilclip by the LapCAC device instead of staplers.
- Trial name
- NCT00250328
- Testing
- LapCAC Laparoscopic Compression Anastomosis Clip
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Hadassah Medical Organization
Colorectal Cancer
Comparison of Laparoscopic Colectomy Versus Open Colectomy for Colorectal Cancer: … A Prospective Randomized Trial
The laparoscopic colectomy has been enthusiastically used by many colorectal surgeons in Taiwan, Japan, Europe, and USA, for around 10 years.
- Trial name
- NCT00155727
- Where
- Taiwan
- Volunteers
- 600 people
- Sponsor
- National Taiwan University Hospital
Ulcerative Colitis
Evaluation of 3D Visualization for Total Colectomy
The anticipated advantages of 3D laparoscopic visualization for the surgeon are greater accuracy and speed in manual skills, translating to decreased operative time, reduced learning curve, and superior safety.We aimed to…
- Trial name
- 3Dvs2DforUC (NCT02370056)
- Testing
- 3-dimensional visualization, 2-dimensional visualization
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- The Cleveland Clinic
Pain, Postoperative, Acute Pain
Efficacy and Safety of VVZ-149 Injections in Patients Undergoing Laparoscopic Colectomy
The purpose of this phase 3 study is to evaluate the efficacy and safety of VVZ-149 Injections for the treatment of postoperative pain following laparoscopic colectomy.
- Trial name
- NCT05764525
- Testing
- VVZ-149 Injections
- Where
- 5 sites in South Korea
- Volunteers
- 285 people
- Sponsor
- Vivozon Pharmaceutical Inc.
Post Abdominal Surgery Pain
A Study Evaluating the Overall Pain Relief and Safety of Intravenous (IV) CR845 in Patients Undergoing Abdominal Surgery
The study schedule is comprised of a 14-day Screening Period, a treatment period and an observation period. All eligible subjects will be randomized into one of 3 treatment groups (1 of 2 dose levels or matched placebo).
- Trial name
- NCT02542384
- Testing
- CR845 IV 1 mcg/kg, CR845 IV 0.5 mcg/kg
- Where
- 23 sites in United States
- Volunteers
- 451 people
- Sponsor
- Cara Therapeutics, Inc.
Surgical Wound Healing, Botulinum Toxin, Type A
Botulinum Toxin Type A for Wound Healing After Laparoscopic Colectomy
This study aims to evaluate the efficacy and safety of botulinum toxin type A (BTX-A) injection as an adjunct to surgical wound healing in patients undergoing laparoscopic colectomy.
- Trial name
- NCT07795463
- Testing
- Botulinum toxin type A (Botox®, Allergan)
- Where
- Vietnam
- Volunteers
- 60 people
- Sponsor
- Pham Ngoc Thach University of Medicine
Colorectal Disorders
Which Type of Laparoscopic Colectomy, Right or Left, Have Better Postoperative Outcomes for the Patients?
Laparoscopic surgery decreased the morbidity of colorectal surgery. The two most common surgeries for colorectal cancer are right and left colectomy.
- Trial name
- NCT04461054
- Where
- Brazil
- Volunteers
- 332 people
- Sponsor
- Leonardo Bustamante-Lopez
Colon Cancer
The Inland Northwest Colon Cancer Survivor's Study
The overall purpose of this study was to address the following questions by describing the trajectory of early survivorship in individuals who undergo both surgical and medical management of colon cancer.
- Trial name
- NCT01775254
- Where
- 4 sites in United States
- Volunteers
- 25 people
- Sponsor
- Washington State University
Pain, Postoperative, Hernia, Ventral
An Open-label Safety and Pharmacokinetic Study of INL-001 in Adults Following Various Open Soft-Tissue Surgeries
This is a multicenter, Phase 3, open-label, safety, tolerability, and characterization of pharmacokinetics study of the INL 001 (bupivacaine HCl) implant, at 300 mg, in patients following various soft-tissue surgeries: open…
- Conditions
- Pain, Postoperative, Hernia, Ventral, Abdominoplasty, Hysterectomy
- Trial name
- NCT04785638
- Testing
- INL-001 (bupivacaine hydrochloride) implant
- Where
- 8 sites in United States
- Volunteers
- 100 people
- Sponsor
- Innocoll
Anastomotic Leak
Anastomotic Leakage in Right Colectomy
Data of patients undergoing elective right colectomy for benign and malignant disease using an open or laparoscopic approach are to be collected in seven colorectal units among Austria for the period between January 2010 and…
- Trial name
- NCT06553261
- Testing
- suturing of leak, lavage, drainage, Formation of a new anasthomosis, Fecal diversion
- Where
- Austria
- Volunteers
- 3,446 people
- Sponsor
- Barmherzige Brüder Vienna
Laparoscopic Colectomy
Epidural Analgesia (EDA) Versus Patient Controlled Analgesia (PCA) in Laparoscopic Colon Surgery
The purpose of this study is to determine whether a epidural analgesia versus patient controlled analgesia reduces the medical recovery in patients undergoing elective laparoscopic colon surgery.
- Trial name
- EVA (NCT00508300)
- Testing
- Epidural analgesia, Patient controlled analgesia
- Where
- Switzerland
- Volunteers
- 128 people
- Sponsor
- University of Lausanne Hospitals
Colectomy
Evaluation of the Benefit of Non-opioid General Anaesthesia on Postoperative Pain in Laparoscopic Colonic Surgery
Evaluation of the benefit of non-opioid general anaesthesia on postoperative pain in laparoscopic colonic surgery
- Trial name
- AGORA (NCT05031234)
- Testing
- anaesthesia without opiates, anaesthesia with morphine
- Where
- France
- Volunteers
- 160 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Mesenteric Vein, Colorectal Surgery
Anatomical Classifications of Henle's Trunk
Right colon has complicated anatomy which is surrounded by important organs. The variations of vessels are more frequent than in left colon, which contribute to the difficulty of surgery.
- Conditions
- Mesenteric Vein, Colorectal Surgery, Henle's Trunk
- Trial name
- HeLaRC (NCT03364881)
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Shanghai Minimally Invasive Surgery Center
Patients Scheduled for Hernia Repair, Cholecystectomy, Right Colectomy, Nissen Fundoplication and Sigmoid Resection
Safety and Performance Evaluation of the AutoLap System
The main objectives of this study are to evaluate the safety and performance of the AutoLap system in Laparoscopic Cholecystectomy procedures.
- Trial name
- NCT01828580
- Testing
- active laparoscope positioner (AutoLap)
- Where
- 3 sites in Israel, Italy and 1 more
- Volunteers
- 36 people
- Sponsor
- M.S.T. Medical Surgery Technology LTD.