Clinical trials: Laparoscopic Colorectal Surgery
Laparoscopic Colorectal Surgery
Oxygen Reserve Index in Laparoscopic Colorectal Surgery
During laparoscopic procedures, certain physiological changes occur due to the creation of pneumoperitoneum. One such change is the reduction in portal venous blood flow, which can lead to decreased liver perfusion and acute…
- Trial name
- NCT07445698
- Testing
- Oxygen Administration During Extubation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Laparoscopic Colorectal Surgery, Postoperative Analgesia
Effect of Oliceridine Analgesia on Postoperative Nause and Vomiting
Postoperative nausea and vomiting (PONV) is common after surgery and impede rapid recovery after surgery. Patients who undergo laparoscopic colorectal surgery are more likely to develop PONV due to the pneumoperitoneum…
- Conditions
- Laparoscopic Colorectal Surgery, Postoperative Analgesia, Oliceridine, Morphine
- Trial name
- NCT06411665
- Testing
- Oliceridine, Morphine
- Where
- China
- Volunteers
- 252 people
- Sponsor
- Peking University First Hospital
Colorectal Cancer (Diagnosis), Laparoscopic Surgery
Superior HypogastrIc plExus bLock During Laparoscopic Colorectal Cancer Surgery
This trial seeks to assess the efficacy of a superior hypogastric plexus block for early quality of recovery after laparoscopic colorectal cancer surgery.
- Conditions
- Colorectal Cancer (Diagnosis), Laparoscopic Surgery, Superior Hypogastric Plexus Block
- Trial name
- SHIELDS (NCT07579780)
- Testing
- Superior hypogastric plexus block
- Where
- China
- Volunteers
- 170 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Laparoscopic Surgery, Colorectal Cancer
Laparoscopic Approach for Emergency Colon Resection
This is a randomized, controlled, parallel, multicenter trial to compare post-operative complications and long-term results between open and laparoscopic technique in emergency colorectal surgery.
- Conditions
- Laparoscopic Surgery, Colorectal Cancer, Colorectal Disorders, Emergencies
- Trial name
- NCT05005117
- Testing
- Laparoscopic operation, Open operation
- Where
- Finland
- Volunteers
- 192 people
- Sponsor
- Joint Authority for Päijät-Häme Social and Health Care
Anesthesia, Posterior Transversus Abdominis Plane Block
Posterior Transversus Abdominis Plane Block Combined With Sacral Multifidus Plane Block Versus Posterior Transversus Abdominis Plane Block for Laparoscopic Colorectal Surgery
The aim of this study is to compare perioperative analgesic efficacy and safety profile of combined SMPB and posterior TAP block versus posterior TAP block in patients undergoing laparoscopic colorectal cancer surgery.
- Conditions
- Anesthesia, Posterior Transversus Abdominis Plane Block, Sacral Multifidus Plane Block, Laparoscopic Colorectal Surgery
- Trial name
- NCT07280949
- Testing
- sacral multifidus plane block, TAP Block: posterior approach
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Laparoscopic Colorectal Cancer Surgery
Effect of Intrathecal Morphine on Quality of Recovery After Laparoscopic Colorectal Cancer Surgery
Colorectal cancer is the second most common tumor in women and the third most common tumor in men, accounting for approximately 10% of tumors diagnosed and tumor-related deaths worldwide each year.
- Trial name
- NCT06636864
- Testing
- Intrathecal morphine, Intrathecal saline injection, TAPB
- Where
- China
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Colorectal Cancer (CRC), Robotic Surgical Procedures
Robot-assisted Surgery for Colorectal Cancer Resection: A Population-based Analysis of Prevalence, Trends and Outcomes
The objective of this research project is to conduct a comparative analysis of short- and long-term outcomes between conventional laparoscopic and robot-assisted resection procedures for colorectal cancer.
- Conditions
- Colorectal Cancer (CRC), Robotic Surgical Procedures, Laparoscopic Abdominal Surgery, Outcome Assessment
- Trial name
- RoChiKoKa (NCT06959849)
- Testing
- Use of robot surgical system
- Volunteers
- 128,000 people
- Sponsor
- Medizinische Hochschule Brandenburg Theodor Fontane
Laparoscopic Colorectal Surgery
Single Incision Laparoscopic Colorectal Surgery
Single incision laparoscopic surgery (SILS) is the further development of the concept of minimally invasive surgery for colorectal cancer,which rapidly developed in the field of colorectal surgery.
- Trial name
- SILCS (NCT03151733)
- Testing
- single incision laparoscopic surgery, conventional laparoscopic surgery
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Ruijin Hospital
Colorectal Neoplasms, Colorectal Surgery
Intraoperative Hyperspectral Imaging for Laparoscopic Surgery
The study aims to evaluate the use of the HyperSnap Surgical System (HSS1) during laparoscopic surgeries, specifically in bowel resections and cholecystectomies.
- Conditions
- Colorectal Neoplasms, Colorectal Surgery, Cholecystitis, Cholecystectomy, Laparoscopic
- Trial name
- LapHSI (NCT06700317)
- Testing
- HSS1
- Volunteers
- 40 people
- Sponsor
- King's College London
Laparoscopic/Minimally Invasive Colorectal Surgery
A Study for Ureter Visualization, Using ASP5354 in Subjects Undergoing Laparoscopic/Minimally Invasive Colorectal Surgery
The primary purpose of this study was to determine the optimal dose of ASP5354 for ureter visualization in participants undergoing laparoscopic/minimally invasive colorectal surgery This study also investigated the safety…
- Trial name
- NCT04238481
- Testing
- Pudexacianinium chloride
- Where
- 2 sites in United States
- Volunteers
- 13 people
- Sponsor
- Astellas Pharma Inc
Peritoneal Metastases, Peritoneal Carcinomatosis
Changes in Coagulation in Colorectal Cancer Patients Undergoing Surgical Treatment
Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (HIPEC) has prolonged the survival substantially for selected patients with peritoneal metastases from colorectal cancer.Bleeding and thromboembolic disease…
- Conditions
- Peritoneal Metastases, Peritoneal Carcinomatosis, Colorectal Neoplasms Malignant, Intestinal Neoplasms
- Trial name
- CONTEST (NCT04744688)
- Where
- 2 sites in Denmark
- Volunteers
- 90 people
- Sponsor
- University of Aarhus
Obese Patients, Laparoscopic Colorectal Surgery
Pharmacodynamics of Injection of Cisatracurium Base on Lean Body Mass Pattern to Maintain Deep Neuromuscular Blockade in Obese Patients
To observe the pharmacodynamics of intravenous injection of cisatracurium to maintain deep neuromuscular blockade in obese patients with lean body mass in laparoscopic colorectal surgery
- Trial name
- NCT05391958
- Testing
- base on Lean Body Mass Pattern, base on Actual Body Weight, obese patients
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- The First Hospital of Qinhuangdao
Anesthesia, General Anesthesia
Effect of Multimodal Opioid-free Anesthesia on Return of Bowel Function in Laparoscopic Colorectal Surgery
The objective of this study is to determine if an opioid-free general anesthetic (OFA) technique utilizing lidocaine, ketamine, dexmedetomidine and magnesium reduce postoperative opioid consumption and speed return of bowel…
- Conditions
- Anesthesia, General Anesthesia, Analgesics, Opioid, Opioid Free Anesthesia
- Trial name
- RUMBLE (NCT04144933)
- Testing
- Acetaminophen, Gabapentin, Lidocaine 1% Injectable Solution, Dexmedetomidine, Ketamine, Dexamethasone, Ondansetron
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of Saskatchewan
Post Operative Pain, Laparoscopic Colorectal Surgery
Analgesic Effect of Bilateral Quadratus Lumborum Block in the End of Colorectal Laparosopic Surgery.
The primary purpose of COLOQUAL study is to demonstrate the superiority of analgesic effect of a bilateral quadratus lumborum block (QLB), performed at the end of laparoscopic colorectal surgery, compared to standard of care.
- Trial name
- Coloqual (NCT03966092)
- Testing
- Quadratus lumborum block
- Where
- France
- Volunteers
- 44 people
- Sponsor
- University Hospital, Clermont-Ferrand
Laparoscopic Colorectal Surgeries
Impact of Intraoperative Deep Neuromuscular Blockade on NOL-guided Opioid Requirement in LSC Colorectal Surgeries
The aim of the present study is to answer the question whether deep neuromuscular blockade has a clinically significant impact on intra and postoperative pain, opioid requirement and anesthesia related outcomes and side effects…
- Trial name
- NCT03910998
- Testing
- Rocuronium IV bolus 0.1 mg/kg guided by TOF that must remain between 1-3 during surgery, Rocuronium IV bolus 0.1 mg/kg guided by TOF 0/4 and PTC≤ 2
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Laparoscopic Colorectal Surgery, Colorectal Cancer
Local Wound Infiltration With 0.5% Levobupivacaine for Postoperative Pain After Laparoscopic Colorectal Surgery.
The study design is a prospective randomized, double-blind, controlled trial of patients who are due to have elective laparoscopic colorectal surgery in Ramathibodhi Hospital.
- Trial name
- NCT03433014
- Testing
- 0.5% Levobupivacaine, Control
- Where
- Thailand
- Volunteers
- 30 people
- Sponsor
- Mahidol University
Laparoscopic Colorectal Surgery
HEAT HumiGard Evaluation Study
During long surgical procedures under general anaesthetic, patients' body temperatures sometimes drop below 36°C. This is classified as hypothermia.
- Trial name
- HEAT (NCT04164706)
- Testing
- HumiGard device
- Where
- United Kingdom
- Volunteers
- 41 people
- Sponsor
- Cardiff and Vale University Health Board
Laparoscopic Colorectal Surgery
Enhanced Recovery After Laparoscopic Colorectal Surgery Study
The study will assess the impact on quality of care after implementation of the ERAS (Enhanced Recovery After Surgery) protocol for laparoscopic colorectal surgery in Vilnius University Hospital Santaros klinikos.
- Trial name
- NCT04091815
- Testing
- Type of anaesthesia
- Where
- Lithuania
- Volunteers
- 100 people
- Sponsor
- Vilnius University
Laparoscopic Colorectal Surgery, Acute Kidney Injury
The Effect of Fluid Management by Pleth Variability Index on Acute Kidney Injury in Obese Patients
This study was to find out whether laparoscopic colorectal surgery is detrimental to the kidneys via PVI monitoring. To detect the kidney injury, so-called kidney troponin NGAL ,which gives earlier information than creatin in…
- Trial name
- NCT03408834
- Testing
- pulse variability index
- Volunteers
- 29 people
- Sponsor
- Ankara University
Colorectal Surgery, Recovery of Function
Impact of a Colorectal Enhanced Recovery Program Implementation on Clinical Outcomes and Institutional Costs
Importance: The Enhanced Recovery Program (ERP) for perioperative care of the surgical patient reduces the postoperative metabolic response and organ dysfunction thereby accelerating functional recovery.
- Conditions
- Colorectal Surgery, Recovery of Function, Laparoscopic Surgery
- Trial name
- NCT03382210
- Testing
- Enhanced recovery protocol
- Volunteers
- 200 people
- Sponsor
- University Hospital of Ferrara