Clinical trials: Laparoscopic Liver Resection
Postoperative Pain After Laparoscopic Liver Resection
Intraoperative Continuous Lidocaine Infusion in Laparoscopic Liver Surgery
The goal of this clinical trial is to learn about effect of intraoperative continuous lidocaine infusion on postoperative pain, gut function and insulin resistance in patients undergoing laparoscopic liver surgery in adults.
- Trial name
- ICLIL (NCT07012889)
- Testing
- lidocaine infusion
- Volunteers
- 94 people
- Sponsor
- Medical University of Warsaw
Malignant Tumor of Liver, Randomized Controlled Trial
Application of ICG@HSA Complexes in Fluorescence Image-Guided Laparoscopic Anatomical Liver Resection
This study is a single-center, prospective, randomized controlled trial that aims to compare the efficacy and safety of a new indocyanine green (ICG) administration protocol with the current guideline-recommended protocol for…
- Trial name
- NCT06219096
- Testing
- NIF image-guided laparoscopic anatomical liver resection with the novel ICG@HSA administration, NIF image-guided laparoscopic anatomical liver resection with the guideline-recommended ICG administration
- Where
- China
- Volunteers
- 100 people
- Sponsor
- West China Hospital
Blood Loss
Effect of Low Tidal Volume on Blood Loss During Laparoscopic Hepatectomy
To explore the effect of low tidal volume on blood loss and gas exchange during laparoscopic hepatectomy
- Trial name
- NCT03399123
- Testing
- Tidal volume
- Where
- China
- Volunteers
- 104 people
- Sponsor
- Southwest Hospital, China
Hepatectomy
Postoperative Biliary Fistula Prevention After Hepatectomy
Aim : Effect of external biliary duct stent after hepatectomy on the occurence of postoperative biliary fistula. Methods : French prospective multicenter randomized trial.
- Trial name
- VPI (NCT01469442)
- Testing
- External Biliary duct stent in the bile duct by cystic way
- Where
- 12 sites in France
- Volunteers
- 304 people
- Sponsor
- University Hospital, Toulouse
Liver Transection During Laparoscopic Liver Resection
Comparison of Hydro-dissection Versus Ultrasonic Aspirator in Division of Liver Parenchyma in Laparoscopic Resection
Background: until now, there is no agreement about the safest and feasible method for liver parenchyma transection during laparoscopic liver resection.
- Trial name
- LLS (NCT03208192)
- Testing
- liver transection during laparoscopic liver resection
- Where
- Russia
- Volunteers
- 68 people
- Sponsor
- Moscow Clinical Scientific Center
Colorectal Liver Metastasis, Laparoscopic Liver Resection
Open vs Laparoscopic Liver Surgery for Colorectal Liver Metastases
This study evaluates the feasibility of laparoscopic surgery in patients diagnosed with colorectal liver metastases. Half of participants will be operated on by laparoscopic approach and the results obtained will be compared with…
- Trial name
- LapOpHuva (NCT02727179)
- Testing
- Liver resection
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Hospital Universitario Virgen de la Arrixaca
HCC - Hepatocellular Carcinoma
Recurrence Patterns and Cost-Effectiveness of Surgical Approaches in Early-Stage Hepatocellular Carcinoma
This study aims to investigate the recurrence patterns and cost-effectiveness of robotic-assisted, laparoscopic, and open liver resections in patients with early-stage (BCLC 0/A) hepatocellular carcinoma.
- Trial name
- NCT06776185
- Testing
- Liver Surgery
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Chen Xiaoping
Liver Cirrhosis, HCC - Hepatocellular Carcinoma
Effect of Laparoscopic Hepatectomy Combined With Splenectomy on Hepatic Functional Reserve and Immune Function
Splenectomy may relieve hypersplenism, reverse liver fibrosis, improve hepatic functional reserve, and reshape the systemic antitumor immune milieu by removing the source of negative immunomodulation.
- Conditions
- Liver Cirrhosis, HCC - Hepatocellular Carcinoma, Hypersplenism
- Trial name
- LHCS-HFRI (NCT07811687)
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Northern Jiangsu People's Hospital
Hepatic Carcinoma, Hepatic Metastasis
Efficacy and Safety of Octreotide in Laparoscopic Hepatectomy Surgery: Effect on Blood Loss, Need for Vasoactive Drugs, Transfusion Requirements.
The goal of this double-blind clinical trial is to compare the efficacy of octreotide versus placebo in laparoscopic hepatectomy surgery in patients diagnosed with resectable hepatocarcinoma or liver metastases.
- Trial name
- NCT06085976
- Testing
- Octreotide
- Where
- Spain
- Volunteers
- 62 people
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Hepatocellular Carcinoma
Laparoscopic Versus Open Major Hepatectomy for HCC Hepatectomy for Hepatocellular Carcinoma
Background: Hepatocellular carcinoma (HCC) is the sixth most common malignancy in the world. Major hepatectomy (resection of > 3 liver segments) is needed if tumor is close to major blood vessels within liver.
- Trial name
- AP-LAPO (NCT04852211)
- Testing
- Open or laparoscopic surgery
- Where
- Hong Kong
- Volunteers
- 212 people
- Sponsor
- Chinese University of Hong Kong
Hepatocellular Carcinoma
Prospective Randomized Trial of Laparoscopic Versus Open Liver Resection for HCC
Short-term outcomes of laparoscopic liver resection is better than those of open liver resection Laparoscopic liver resection is better than open resection in immunological aspects
- Trial name
- HCC (NCT00606385)
- Testing
- Liver resection
- Where
- South Korea
- Volunteers
- 84 people
- Sponsor
- Seoul National University Hospital
Liver Diseases
Enhanced Recovery After Surgery Protocal Versus Traditional Care in Laparoscopic Hepatectomy
The purpose of this study is to investigate the clinical value of enhanced recovery after surgery protocal in laparoscopic hepatectomy by assessing its outcomes and hospital stay days comparing with traditional care .
- Trial name
- NCT02533193
- Testing
- ERAS perioperative cares, Conventional perioperative cares
- Where
- China
- Volunteers
- 126 people
- Sponsor
- Sir Run Run Shaw Hospital
Liver Neoplasms, Postoperative Complications
Intraoperative Continuous Terlipressin Infusion is Associated With Reduced Severe Postoperative Complications After Laparoscopic Hepatectomy: a Prospective Propensity Score-matched Cohort Study
Liver resection is an important surgical treatment for patients with liver diseases. Despite advances in surgical and anesthetic management, postoperative complications remain a major concern and may affect patient recovery.
- Trial name
- NCT07719933
- Testing
- terlipressin
- Where
- China
- Volunteers
- 161 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Laparoscopic Liver Resection, Open Liver Resection
Short and Long Outcomes Between Laparoscopic and Open Hepatectomy
LLR was applied for tumors located at the lower edge and lateral segments of the liver that could be resected more easily than posterosuperior segments.
- Trial name
- NCT03672357
- Testing
- Laparoscopic liver resection, Open liver resection
- Where
- China
- Volunteers
- 80 people
- Sponsor
- hui hou
Hepatocellular Carcinoma
Laparoscopic Surgery Versus Radiofrequency Ablation for Recurrent HCC
Hepatocellular carcinoma (HCC) is the fifth most common and the third leading cause of death from cancer worldwide1 . Hepatectomy is still the main effective treatment for HCC accompanying with well-preserved cirrhosis when liver…
- Trial name
- NCT02535117
- Testing
- Laparoscopic Surgery(LS), RFA
- Volunteers
- 216 people
- Sponsor
- Sun Yat-sen University
Liver Lesions Requiring Hemihepatectomy
The ORANGE II PLUS - Trial: Open Versus Laparoscopic Hemihepatectomy
The added value of the laparoscopic hemihepatectomy compared to the open hemihepatectomy has never been studied in a randomized controlled setting.
- Trial name
- NCT01441856
- Testing
- Open or Laparoscopic left hemihepatectomy, Open or Laparoscopic right hemihepatectomy
- Where
- 16 sites in Belgium, Germany and 4 more
- Volunteers
- 350 people
- Sponsor
- Maastricht University Medical Center
Paracaval Portion
Laparoscopic Versus Open Surgery for Lesions Originating in the Paracaval Portion of the Caudate Lobe
This study aimed to evaluate the safety, feasibility and efficacy of laparoscopic for resecting paracaval-originating lesions by contrast of open procedures.
- Trial name
- NCT04499261
- Testing
- laparoscopic surgery, Open surgery
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Southwest Hospital, China
Primary Liver Carcinoma
Laparoscopic Hepatectomy Versus Open Hepatectomy for PHC
The purpose of this study is to compare short-term and long-term efficacy of laparoscope hepatectomy and open hepatectomy, evaluate the safety and efficacy of laparoscope hepatectomy the PHC with a tumor size of 5～10㎝,and provide…
- Trial name
- NCT02014025
- Testing
- Open hepatectomy, Laparoscope hepatectomy
- Where
- China
- Volunteers
- 335 people
- Sponsor
- Shuguo Zheng, MD
Laparoscopic Hepatectomy
Effect of TEE-guided Non-fluid Limited Combined With Dobutamine on Hepatic Venous Blood Flow Spectrum
Patients meeting enrollment criteria will be randomized 1:1 to either the dobutamine or the control group. In the dobutamine group, 3~6μg/kg/min dobutamine will be injected intravenously after anesthesia induction until…
- Trial name
- NCT06210217
- Testing
- Dobutamine hydrochloride, Injectable, 0.9% normal saline
- Where
- China
- Volunteers
- 51 people
- Sponsor
- Sichuan University
Laparoscopic Hepatectomy
Feasibility and Impact of ICG and 4K Overlay in Laparoscopic Hepatic Surgery on Real-time Tumor Detection
Achievement of tumor-free resection margin with the largest possible remnant liver parenchyma is the major challenge in hepatic surgery.
- Trial name
- LiverLight (NCT04946591)
- Where
- Germany
- Volunteers
- 45 people
- Sponsor
- Klinikum Saarbrücken, Klinik für Allgemein-, Viszeral- und Thoraxchirurgie, Chirurgische Onkologie