Clinical trials: Laparoscopic Proximal Gastrectomy
Anastomotic Leak
Endo-Vac-Therapy for Post-Sleeve Gastrectomy Leaks
Endoscopic negative pressure therapy (ENPT) is a safe technique, showing promising results in the treatment of leakages of the upper and lower gastrointestinal tract.
- Trial name
- NCT05189574
- Testing
- Endoscopic negative pressure therapy
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Ruhr University of Bochum
Proximal Early Gastric Cancer
The Anti-reflux Effect of Double-flap Technique in Laparoscopic Proximal Gastrectomy.
This study is a multicenter, open-label, prospective, randomized parallel-controlled trial. The purpose is to explore whether the incidence rate of reflux esophagitis (RE) within 12 months after surgery is non-inferior for the…
- Trial name
- NCT06511609
- Testing
- double-flap technique（DFT）; double-tract reconstruction(DTR),
- Volunteers
- 244 people
- Sponsor
- Changzhi People's Hospital Affiliated to Changzhi Medical College
Gastric Cancer
Comparison of Laparoscopic Proximal Gastrectomy and Laparoscopic Total Gastrectomy
Experimental: Laparoscopic proximal gastrectomy Laparoscopy proximal gastrectomy with esophago-jejunostomy, gastro-jejunostomy and jejuno-jejunostomy (double tract reconstruction).
- Trial name
- NCT02892643
- Testing
- Laparoscopic proximal gastrectomy, Laparoscopic total gastrectomy
- Where
- 16 sites in South Korea
- Volunteers
- 138 people
- Sponsor
- Seoul National University Bundang Hospital
Stomach Neoplasms, Adenocarcinoma - Gastroesophageal Junction (GEJ)
The Efficacy and Safety of Laparoscopic Proximal Gastrectomy With LPG-tbROSF Versus LTG for Localized Proximal Gastric Cancer.
This clinical trial is evaluating a new, function-preserving surgical technique for patients with early-stage cancer in the upper part of the stomach.
- Conditions
- Stomach Neoplasms, Adenocarcinoma - Gastroesophageal Junction (GEJ), Gastroesophageal Junction Cancer
- Trial name
- NCT07260461
- Testing
- Laparoscopic Proximal Gastrectomy with Tubular Stomach-Based Right-Opening Single Flap Valvuloplasty (LPG-tbROSF)
- Volunteers
- 120 people
- Sponsor
- First Affiliated Hospital of Wenzhou Medical University
Early Gastric Cancer, Adenocarcinoma of the Stomach
SPADE Clinical Trial.
Purpose: This multicenter, prospective, single-arm phase 2 clinical trial aims to evaluate the safety, feasibility, and clinical outcomes of the SPADE operation (Spade-Shaped Anastomosis) in patients undergoing laparoscopic or…
- Conditions
- Early Gastric Cancer, Adenocarcinoma of the Stomach, Proximal Gastric Cancer, SPADE Operation
- Trial name
- SPADE (NCT07892183)
- Testing
- Spade-Shaped Anastomosis after Laparoscopic or Robotic Proximal Gastrectomy Using Double Suture Anchoring between the Posterior Wall of the Esophagus and the Anterior Wall of the Stomac
- Where
- South Korea
- Volunteers
- 159 people
- Sponsor
- National Cancer Center, Korea
Splenic Hilum Lymph Nodes Dissection
3D Versus 2D Laparoscopic Total Gastrectomy With Splenic Hilum Lymph Nodes Dissection
The investigators will perform a prospective randomized comparison between 3D and 2D laparoscopic total gastrectomy with splenic hilum lymph nodes dissection.
- Trial name
- NCT02984787
- Testing
- 3D Laparoscopic total gastrectomy, 2D Laparoscopic total gastrectomy
- Where
- China
- Volunteers
- 480 people
- Sponsor
- Chinese PLA General Hospital
Proximal Gastric Adenocarcinoma, Adenocarcinoma of Esophagogastric Junction
A Modified Esophagogastric Reconstruction Method After Laparoscopic Proximal Gastrectomy
The double-flap technique (DFT) is an effective digestive tract reconstruction method after proximal gastrectomy (PG) to reduce the incidence of postoperative reflux esophagitis.
- Conditions
- Proximal Gastric Adenocarcinoma, Adenocarcinoma of Esophagogastric Junction, Anastomosis
- Trial name
- NCT05829213
- Testing
- "arch-bridge-type" esophagogastric reconstruction after proximal gastrectomy
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Peking University
Gastric Cancer Patients Undergoing Minimally Invasive Gastrectomy
Application of a New Surgical Technique in Proximal Gastrectomy: a Prospective, Multicenter Randomized Controlled Study
This is a prospective study using a multicenter, randomized, controlled, open label, and efficacy validated approach.At present, there is no universally recognized optimal method for gastrointestinal reconstruction after proximal…
- Trial name
- NCT06679244
- Testing
- Totally laparoscopic proximal gastrectomy with Hao's esophagogastrostomy by fissure technique, Totally laparoscopic proximal gastrectomy with double-tract reconstruction
- Where
- 3 sites in China
- Volunteers
- 52 people
- Sponsor
- Huashan Hospital
Gastric Cancer, Adenocarcinoma of Esophagogastric Junction
A Prospective Study on Esophagogastrostomy by an Innovative Surgical Technique
This is a single-center, open-label, Phase Ib/II study aiming to assess the perioperative safety and postoperative outcomes of a novel surgical technique in treating primary adenocarcinoma located in the upper 1/3 of the stomach…
- Trial name
- NCT06300879
- Testing
- Performing totally laparoscopic proximal gastrectomy with esophagogastrostomy by fissure technique
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Huashan Hospital
Anti-Reflux Alimentary Reconstruction, Laparoscopic Proximal Gastrectomy
A 3-Arm Study Comparing the Efficacy of Anti-Reflux Reconstruction Protocols After Laparoscopic Proximal Gastrectomy
The efficacy of three different alimentary reconstruction methods after proximal gastrectomy will be investigated in this study in a prospective, multicenter, randomized controlled trial.
- Conditions
- Anti-Reflux Alimentary Reconstruction, Laparoscopic Proximal Gastrectomy, Siewert Type II/III Adenocarcinoma of the Esophagogastric Junction
- Trial name
- NCT06347757
- Testing
- Anti-Reflux Alimentary Reconstruction After Laparoscopic Proximal Gastrectomy
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Northern Jiangsu People's Hospital
Gastric Cancer
Laparoscopic Versus Open Gastrectomy With Splenic Hilum Lymph Nodes Dissection
Splenic hilum remains challenging during total gastrectomy with D2 lymphadenectomy.The application of minimally invasive surgery for advanced gastric cancer is gaining popularity.
- Trial name
- NCT02980861
- Testing
- Laparoscopic total gastrectomy, Open total gastrectomy
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Chinese PLA General Hospital
Gastroesophageal-junction Cancer, Proximal Gastrectomy
A Clinical Study of Laparoscopic Proximal Gastrectomy Based on PTST(Parachute-tunnel- Style Technique) Esophagogastric Anastomose.
1. To evaluate the safety, simplicity and effectiveness of the gastric function (anti-reflux) preservation of the innovative "parachute-tunnel-style technique" (PTST) in laparoscopic proximal gastrectomy. 2.
- Conditions
- Gastroesophageal-junction Cancer, Proximal Gastrectomy, Gastroesophagostomy
- Trial name
- NCT06217991
- Testing
- PTST(parachute-tunnel-style technique)for esophagogastrostomy
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Tang-Du Hospital
Gastroesophageal Junction (GEJ) Cancer, Gastric Cancer
The Effect of Different Digestive Tract Reconstruction Methods on Postoperative Quality of Life After Proximal Gastrectomy
Gastric cancer ranks as the fifth most common malignancy worldwide and the fourth leading cause of cancer-related deaths. In China, its incidence and mortality rank third among all cancers.
- Trial name
- STARS-GC10 (NCT06929949)
- Where
- China
- Volunteers
- 90 people
- Sponsor
- The First Hospital of Jilin University
Gastric Cancer
ERAS (Early Recovery After Surgery) Protocol After Laparoscopic Total Gastrectomy and Proximal Gastrectomy
Enhanced Recovery After Surgery (ERAS) programs have been introduced with purposes of reducing the surgical stress response and obtaining optimal recovery after surgery.
- Trial name
- NCT03079596
- Testing
- ERAS perioperative cares, Conventional perioperative cares
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Seoul National University Bundang Hospital
Gastric Cancer
Safety Comparison of Total Laparoscopic Proximal Gastrectomy With or Without Preservation of the Celiac Branch of the Vagus Nerve for Early Upper Gastric Cancer: A Randomized Controlled Clinical Trial
This prospective, single-center, randomized, controlled, non-inferiority clinical trial aims to compare the safety and postoperative quality of life of early upper gastric cancer patients undergoing total laparoscopic proximal…
- Trial name
- TLPG-CBVP (NCT07142122)
- Testing
- Total laparoscopic proximal gastrectomy with preservation of both the hepatic and celiac branches of the vagus nerve, followed by double-tract reconstruction., Total laparoscopic proximal gastrectomy with preservation of the hepatic branch of the vagus nerve but deliberate resection of the celiac branch, followed by double-tract reconstruction.
- Where
- China
- Volunteers
- 76 people
- Sponsor
- Fujian Cancer Hospital
Gastric Cancer, Reflux Esophagitis
Preliminary Efficacy Analysis of 'λ+α' Double-Tract Reconstruction After Laparoscopic Proximal Gastrectomy
The incidence of proximal gastric cancer has increased significantly in recent years. This may be due to weight gain, alcohol consumption, gastroesophageal reflux disease (GERD), and precancerous lesions.
- Trial name
- NCT06475170
- Testing
- proximal gastrectomy combined with 'λ+α' double-tract anastomosis
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Northern Jiangsu People's Hospital
Gastric Cancer
Laparoscopy-assisted Proximal Gastrectomy Versus and Laparoscopy-assisted Total Gastrectomy
The choice of surgical strategy for patients with proximal gastric cancer is controversial mainly because proximal gastrectomy is infamous for high rates of reflux symptoms and anastomotic stricture.
- Trial name
- PRAPT (NCT01433861)
- Testing
- Laparoscopy-assisted gastrectomy
- Where
- South Korea
- Volunteers
- 7 people
- Sponsor
- Seoul National University Bundang Hospital
Gastric Cancer, Splenic Hilum Lymph Nodes Dissection
Laparoscopic-assisted Total Gastrectomy Versus Open Total Gastrectomy With Splenic Hilum Lymph Nodes Dissection
This study investigates the safety and feasibility of laparoscopic-assisted total gastrectomy with spleen-preserving splenic hilum lymph node dissection for proximal advanced gastric cancer and compares the early results of this…
- Conditions
- Gastric Cancer, Splenic Hilum Lymph Nodes Dissection, Total Gastrectomy
- Trial name
- NCT02711033
- Testing
- Laparoscopic-assisted total gastrectomy, Open total gastrectomy
- Where
- China
- Volunteers
- 144 people
- Sponsor
- Guangdong Provincial Hospital of Traditional Chinese Medicine
Morbid Obesity
Comparison of Laparoscopic Sleeve Gastrectomy and Roux-Y-gastric Bypass in the Treatment of Morbid Obesity
The laparoscopic sleeve-gastrectomy (SG) compared to laparoscopic proximal Roux-Y-gastric bypass (PGB) is as successful in the treatment of morbid obesity in the majority of patients.
- Trial name
- NCT00356213
- Testing
- sleeve gastrectomy, Roux-Y-gastric bypass
- Volunteers
- 217 people
- Sponsor
- University Hospital, Basel, Switzerland
Stomach Neoplasms
Laparoscopic Proximal Gastrectomy With Double-flap Technique Versus Laparoscopic Total Gastrectomy With Roux-en-Y Reconstruction for Proximal Early Gastric Cancer
Proximal early gastric cancer can choose radical total gastrectomy or proximal gastrectomy. But if use simple esophagogastric anastomosis for proximal gastrectomy, the incidence of postoperative reflux esophagitis is up to 62%…
- Trial name
- NCT05890339
- Testing
- Laparoscopic Proximal Gastrectomy With Double-flap Technique, Laparoscopic Total Gastrectomy With Roux-en-Y Reconstruction
- Where
- China
- Volunteers
- 216 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University