Clinical trials: Laparoscopic Roux-en-y Gastric Bypass
Obesity
Endostapler Gastric Bypass Study
The goal of this prospective, post-market study is to evaluate safety and efficacy of the AEON™ Endostapler when used in laparoscopic Roux-en-Y gastric bypass surgery.
- Trial name
- NCT04712526
- Testing
- AEON Endostapler
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Lexington Medical Inc.
Intestinal Perforation
Evaluation of the Ability to Detect Bowel Gas During Laparoscopic Surgery
This study will determine the ability of the device to draw a small amount of gas from an insufflated abdomen during laparoscopic surgery and accurately detect if gaseous content from the bowel is present.
- Trial name
- NCT02679118
- Testing
- Sentire
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Dan E. Azagury
Laparoscopic Gastric Bypass Surgery, Ketamine
Perioperative Ketamine for Pain With Gastric Bypass
Opioid medications such as morphine, hydrocodone and oxycodone are standard for treating pain after surgery, however there are disadvantages.
- Trial name
- NCT03448068
- Testing
- Ketamine, Standard therapy
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Diabetes Mellitus, Type 2
Laparoscopic Gastric Bypass for Type 2 Diabetes Mellitus With Body Mass Index (BMI) < 35
The aim of this study is to evaluate the effect of Roux-en-y gastric bypass (RYGB) in controlling diabetes in subjects with mild obesity (BMI 26-35).
- Trial name
- NCT00999050
- Testing
- Gastric bypass for diabetic patients <35 BMI
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Weill Medical College of Cornell University
Anastomosis, Roux-en-Y, Surgical Operation With Anastomosis, Bypass or Graft
Comparison of Laparoscopic Traditional and Knotless Sutures
Background Excess weight and obesity is the fifth leading risk factor for global death. Bariatric surgery is considered as the only effective long-term treatment for morbid obesity.
- Trial name
- NCT02720718
- Testing
- Stratafix, Vicryl
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- AZ St.-Dimpna Geel
Morbid Obesity
Laparoscopic Sleeve Gastrectomy Versus Roux-en-Y Gastric Bypass
Prospective randomized clinical trial aiming to compare laparoscopic Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) with primary outcome on excess weight loss, and secondary outcomes on nutritional status, glycolipid…
- Trial name
- NCT02475590
- Testing
- Laparoscopic sleeve gastrectomy, Laparoscopic Roux-en-Y gastric bypass
- Where
- France
- Volunteers
- 100 people
- Sponsor
- IHU Strasbourg
Morbid Obesity, Postoperative Complications
Laparoscopic Roux-en-Y Gastric Bypass Versus Laparoscopic One Anastomosis Gastric Bypass
This study try to identify differences in cost, length of operation and results between two different bariatric surgical techniques, the laparoscopic Roux-en-Y gastric bypass and the Single anastomosis laparoscopic gastric…
- Conditions
- Morbid Obesity, Postoperative Complications, Weight Loss
- Trial name
- OAGB-vs-LRYGB (NCT02779322)
- Testing
- Minigastric bypass, Gastric bypass
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Puerta de Hierro University Hospital
Post-operative Pain Management
Efficacy of Exparel (TM) on Post-operative Pain After Laparoscopic Gastric Bypass Using Circular EEA Stapler
This will be a comparative study between two cohorts of patients undergoing Roux-en-Y Gastric bypass. One cohort (75 patients) will receive FDA approved Exparel® (liposome bupivacaine injection solution) injections…
- Trial name
- NCT03187379
- Testing
- Exparel, Bupivacaine
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Matthew Kroh
Inadequate Initial Weight Loss, Persistent Clinically Severe Obesity
Laparoscopic Revision Gastric Bypass for Inadequate Initial Weight Loss
The main aim of this study is to analyze and report traditional, patient-centered, and composite intermediate-term outcomes after laparoscopic revision Roux-en-Y gastric bypass surgery for inadequate initial weight loss.
- Trial name
- IIWL (NCT01040377)
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- University of California, San Francisco
Laparoscopic Sleeve Gastrectomy, Sleeve Gastrectomy
A Retrospective Multicenter Comparison of Laparoscopic and Robotic-Assisted Roux-en-Y Gastrectomy
The prevalence of obesity has tripled in the last 50 years with presently about 1.7 billion of the world population aged 18 years and over either overweight or obese.1 In the US alone, 35% of the population is obese.2 Although…
- Trial name
- NCT05224791
- Testing
- Roux-en-Y Gastric Bypass, Sleeve Gastrectomy
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Methodist Health System
Diabetes, Stress
Effects of Different Types of Anesthesia on Stress Response in Laparoscopic Gastric Bypass for Type 2 Diabetes Mellitus
General anesthesia can be considered as a combination of hypnosis, antinociception and immobility. Explore the effect of three kinds of anesthesia,that is the total intravenous anesthesia, inhalation anesthesia and inhalation and…
- Conditions
- Diabetes, Stress, Anesthesia
- Trial name
- NCT01963546
- Testing
- different types of anesthesia, Dexmedetomidine
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Guangzhou General Hospital of Guangzhou Military Command
Obesity, Diabetes
Laparoscopic Roux-en-Y Gastric Bypass Versus Laparoscopic Biliopancreatic Diversion (BPD)- Duodenal Switch for Superobesity
The purpose of this study is to compare the outcome in a broad perspective after laparoscopic Roux-en-Y gastric bypass and laparoscopic BPD-duodenal switch in the treatment of superobesity (body mass index [BMI] > 50 kg/m2).
- Conditions
- Obesity, Diabetes, Hypertension
- Trial name
- ASGARD (NCT00327912)
- Testing
- Laparoscopic Biliopancreatic diversion with Duodenal switch, Laparoscopic Roux-en-Y Gastric Bypass
- Where
- 2 sites in Norway, Sweden
- Volunteers
- 60 people
- Sponsor
- Göteborg University
Bariatric Surgery
30-Days Post-Operative Complications in Bariatric Surgery
comparison of 30-days post-operative outcomes of laparoscopic sleeve gastrectomy (LSG) and laparoscopic Roux-en-Y gastric bypass (LRYGB)
- Trial name
- Bariatric (NCT04779723)
- Testing
- Comparison of two Techniques of bariatric surgery
- Where
- Pakistan
- Volunteers
- 116 people
- Sponsor
- Multan Medical And Dental College
Bariatric Surgery, Hormonal Response
Comparison of Hormonal Response to a Mixed-Meal Tolerance Test After Laparoscopic Roux-en-Y Gastric Bypass Versus Laparoscopic Sleeve Gastrectomy With Duodenojejunal Bypass in Patients With Super Morbid Obesity
Obesity is a major global health problem. Bariatric surgery is the most effective treatment, leading to substantial weight loss and improvement in obesity-related comorbidities.
- Conditions
- Bariatric Surgery, Hormonal Response, Post Bariatric Hypoglycemia
- Trial name
- CU BYPASS-DJB (NCT07747779)
- Testing
- Sleeve gastrectomy with duodenojejunal bypass, Roux-en-Y gastric bypass
- Where
- Thailand
- Volunteers
- 32 people
- Sponsor
- Chulalongkorn University
Nutritional Deficiency
Nutritional Deficiency After Bariatric Surgeries
comparing micro-nutrient deficiencies in postoperative morbid obese patients who will be undergoing gastric bypass and sleeve gastrectomy with regards to vit B 12, vitamin D,iron studies and calcium .
- Trial name
- NCT04717973
- Testing
- laboratory testing of CBC, serum ferritin, and vitamin B 12
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Sohag University
Laparoscopic Gastric Bypass, Obesity
Ketamine vs Hydromorphone
This study will help to determine if investigators can minimize narcotic use in laparoscopic gastric bypass patients while maintaining adequate pain control.
- Conditions
- Laparoscopic Gastric Bypass, Obesity, Pain, Postoperative
- Trial name
- NCT03001843
- Testing
- Ketamine, Narcotics, pain scale
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- University of Florida
Morbid Obesity
Long-term Adverse Effects After Bariatric Surgery on Oesophagus Epithelium
The goal of this trial is to examine long-term effects of laparoscopic gastric bypass (LRYGB) and sleeve gastrectomy (LSG) on oesophageal symptoms and disease, including the presence of Barrett oesophagus ≥ 5 years post-surgery.
- Trial name
- FUB-B (NCT03410849)
- Testing
- Gastroscopy
- Where
- Switzerland
- Volunteers
- 170 people
- Sponsor
- University Hospital, Basel, Switzerland
Bariatric Surgery
Novel Technique in Closure of Mesenteric Defects After Laparoscopic Roux-en-Y Gastric Bypass and Its Effect on Internal Hernia: a Case-control Study
This study is to investigate the rate of internal hernia after laparoscopic Rox-en-Y gastric bypass when the defects are closed using cyano-acrylate glue.
- Trial name
- NCT04788199
- Testing
- Closure of mesenteric defects using glue
- Where
- United Kingdom
- Volunteers
- 928 people
- Sponsor
- Mansoura University
Type 2 Diabetes Mellitus, Obesity
Silastic Ring Gastric Bypass Versus Sleeve Gastrectomy for Type 2 Diabetes Mellitus in Obese Patients
Type 2 diabetes (T2DM) and obesity are becoming increasingly common in New Zealand (NZ) and worldwide. Both are associated with a risk of early mortality (death).
- Trial name
- NCT01486680
- Testing
- Laparoscopic Silastic Ring Roux-en-Y Gastric Bypass, Laparoscopic Sleeve gastrectomy
- Where
- 2 sites in New Zealand
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- North Shore Hospital, New Zealand
Obesity, Gastric Reflux
The Bioavailability and Effect on Pouch pH of Esomeprazole After Gastric Bypass
The objective of this study is to investigate the effect of Esomeprazol administered in tablets (Esomeprazol MUT Sandoz® 40mg) or in solution (Esomeprazol MUT Sandoz® 40mg in 10ml tap water) on acid production in the gastric…
- Conditions
- Obesity, Gastric Reflux, Ulcer, Gastric
- Trial name
- NCT05320796
- Testing
- upper endoscopy
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Prof Urs Zingg