Clinical trials: Laparoscopic Sleeve Gastrectomy
Bariatric Sleeve Gastrectomy
Impact of Asprosin and Neuregulin 4 on Metabolic Parameters, Anthropometric Indices and Body Composition After Laparoscopic Sleeve Gastrectomy
Asprosin and neuregulin 4 (NRG4) sit on opposing arms of adipose endocrine physiology. Asprosin is a fasting-induced, white adipose-derived glucogenic and orexigenic hormone that rises with adiposity and insulin resistance.
- Trial name
- NCT07806448
- Testing
- sleeve gastrectomy
- Where
- Egypt
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- General Committee of Teaching Hospitals and Institutes, Egypt
Morbid Obesity, Diabetes
Factors Influencing the Positive Outcome of Bariatric Surgery for Morbidly Obese Patients
The purpose of this study is to report data with patients after bariatric surgery.
- Conditions
- Morbid Obesity, Diabetes, Hypertension
- Trial name
- NCT01583790
- Where
- Israel
- Volunteers
- 2,000 people
- Sponsor
- Assuta Hospital Systems
Obesity, Obesity, Morbid
Weight Loss and Aggression
Obesity has become an important medical and social problem in western countries today. Although many surgical procedures are performed for obesity, Laparoscopic sleeve gastrectomy (LSG) has become the most common bariatric…
- Conditions
- Obesity, Obesity, Morbid, Aggression
- Trial name
- NCT05654584
- Testing
- laparoscopic sleeve gastrectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Visceral Pain, Bariatric Surgery Candidate
Paragastric Autonomic Blockade to Prevent Visceral Pain After Laparoscopic Sleeve Gastrectomy
Visceral pain (VP) following laparoscopic sleeve gastrectomy remains a substantial problem. VP is associated with autonomic symptoms, especially nausea and vomiting, and is unresponsive to traditional pain management algorithms…
- Conditions
- Visceral Pain, Bariatric Surgery Candidate, Pain, Postoperative, Vomiting, Postoperative
- Trial name
- PG-ANB (NCT05353426)
- Testing
- Paragastric autonomic neural blockade
- Where
- Colombia
- Volunteers
- 145 people
- Sponsor
- Universidad Simón Bolívar
Obesity, Bariatric Surgery
Modified Thoracoabdominal Nerve Plane Block In Laparoscopic Sleeve Gastrectomy
Ultrasound-guided Modified Thoracoabdominal Nerve Plane Block (M-TAPA) is performed into the costochondral aspect at the 9th-10th costal level by injecting local anesthetics deep into the chondrium.
- Conditions
- Obesity, Bariatric Surgery, Laparoscopic Sleeve Gastrectomy, Acute Post Operative Pain
- Trial name
- NCT06515691
- Testing
- M-TAPA block, Postoperative pain management
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul Medipol University Hospital
Obesity, Morbid
Ambulatory Laparoscopic Sleeve Gastrectomy
In the era of laparoscopic surgery, day case procedures are increasingly practiced around the world, however, day case bariatric surgery remains a controversial issue due to lack of sufficient evidence evaluating its safety.
- Trial name
- DAYSLEEVE (NCT05106660)
- Testing
- Ambulatory Laparoscopic Sleeve Gastrectomy, Conventional Laparoscopic Sleeve Gastrectomy
- Where
- Saudi Arabia
- Volunteers
- 1,554 people
- Sponsor
- King Saud University
Nutritional Deficiency
Nutritional Deficiency After Bariatric Surgeries
comparing micro-nutrient deficiencies in postoperative morbid obese patients who will be undergoing gastric bypass and sleeve gastrectomy with regards to vit B 12, vitamin D,iron studies and calcium .
- Trial name
- NCT04717973
- Testing
- laboratory testing of CBC, serum ferritin, and vitamin B 12
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Sohag University
Osteoarthritis of Knee, Arthroplasties, Knee Replacement
Morbid Obesity and Severe Knee Osteoarthritis - Which Should Be Treated First?
The goal of this study is to determine whether undergoing bariatric surgery before knee replacement leads to better outcomes compared to undergoing knee replacement before bariatric surgery.
- Conditions
- Osteoarthritis of Knee, Arthroplasties, Knee Replacement, Sleeve Gastrectomy
- Trial name
- NCT06767787
- Testing
- laparoscopic sleeve gastrectomy, total knee arthroplasty
- Where
- 2 sites in Canada
- Volunteers
- 142 people
- Sponsor
- Memorial University of Newfoundland
Morbid Obesity, Hiatal Hernia
Laparoscopic Sleeve Gastrectomy With or Without Hiatal Hernia Repair in Morbidly Obese Patients
Background: Obesity and hiatal hernia are both risk factors of gastroesophageal reflux disease (GERD), and the incidence of hiatal hernia is much higher in morbidly obese patients.
- Conditions
- Morbid Obesity, Hiatal Hernia, Gastroesophageal Reflux Disease, Sleeve Gastrectomy
- Trial name
- NCT03776669
- Testing
- Laparoscopic sleeve gastrectomy + Hiatal hernia repair, Laparoscopic sleeve gastrectomy alone
- Where
- Taiwan
- Volunteers
- 70 people
- Sponsor
- National Taiwan University Hospital
"Pulmonary Complications"
Comparison of Pulmonary Complications Related to Sleeve Gastrectomy and Gastric Banding
Comparison of Pulmonary Complications related to laparoscopic sleeve gastrectomy and laparoscopic adjustable gastric banding.
- Trial name
- NCT01178567
- Where
- Israel
- Volunteers
- 307 people
- Sponsor
- Meir Medical Center
Pain
Effect of Peritoneal Lavage With Clindamycin-gentamicin on Laparoscopic Sleeve Gastrectomy
A prospective, randomized study will be performed in patients undergoing laparoscopic sleeve gastrectomy (LSG) as bariatric procedure.
- Trial name
- NCT02479971
- Testing
- Clindamycin-gentamicin irrigation, Normal saline irrigation
- Volunteers
- 60 people
- Sponsor
- Hospital General Universitario Elche
Bariatric Surgical Procedures, Anesthesia and Analgesia
Comparison of Abdominal Plane Blocks in Postoperative Pain Control in Patients Undergoing LSG
The goal of this prospective observational study is compare in terms of efficiency and complications transversus abdominis plane (TAP) and Modified thoracoabdominal plane block-perichondrial approach (M-TAPA) blocks in patients…
- Conditions
- Bariatric Surgical Procedures, Anesthesia and Analgesia, Anesthesia, Regional
- Trial name
- NCT06201546
- Testing
- TAP block group, m-TAPA block group
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Pain, Postoperative
Effect of Preincisional Bupivakain Infiltration on Postoperative Narcotic Medication Requirement
Postoperative pain and use of narcotic analgesics after laparoscopic bariatric surgeries are problems that need to be solved in terms of patient comfort.
- Trial name
- NCT03071991
- Testing
- study group, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Umraniye Education and Research Hospital
Bariatric Surgery Candidate
Ultrasonograpahic Evaluation of Diaphragmatic Functions in Obese Patients Undergoing Laparoscopic Sleeve Gastrectomy
Major laparoscopic sleeve gastrectomy surgery requires steep Trendelenburg position with pneumoperitoneum for a long time leading to decrease pulmonary compliance and lung volumes due to cephalic displacement and decrease…
- Trial name
- NCT04130217
- Testing
- addition of positive end expiratory pressure in ventilated patients, addition of positive end expiratory pressure and recruitment maneuver in ventilated patients
- Where
- Egypt
- Volunteers
- 69 people
- Sponsor
- Zagazig University
Vomiting, Postoperative
Staple Line Inversion vs Buttressing on Postoperative Vomits After LSG
Patients undergoing laparoscopic sleeve gastrectomy will be randomized into 2 groups. In one group, a staple line inversion with a running suture of Polypropylene will be performed.
- Trial name
- NCT03104023
- Testing
- Staple line inversion, Staple line buttressing
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Hospital General Universitario Elche
Skeletal Muscle, Bariatric Surgery
Circulating Muscle-specific microRNAs and Renal, Nutritional and Inflammatory Biomarkers of Skeletal Muscle Loss During the First 18 Months After Laparoscopic Sleeve Gastrectomy
Metabolic and bariatric surgery produces substantial and durable weight loss, but a considerable proportion of that loss is not adipose tissue.
- Trial name
- NCT07806513
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- General Committee of Teaching Hospitals and Institutes, Egypt
Heart Failure, Obesity
Laparoscopic Sleeve Gastrectomy as Bridge-to-Candidacy for Obese Left-Ventricular Assist Device Patients
In LVAD (Left-Ventricular Assist Device) patients, evidence is lacking regarding the safety and efficacy of Laparoscopic Sleeve Gastrectomy (LSG) as a means to reach a Body Mass Index (BMI) within listing criteria for heart…
- Trial name
- LSG-BTC-LVAD (NCT03008096)
- Testing
- Laparoscopic Sleeve Gastrectomy
- Where
- Austria
- Volunteers
- 10 people
- Sponsor
- Philipp Angleitner
Bariatric Surgery Candidate, Cholelithiases
Multicenter Cohort of 768 High-risk Patients With Symptomatic Gallstones, Adding Cholecystectomy Did Not Increase Length of Stay or Perioperative Morbidity, Supporting it as a Safe Single-stage Option
Despite numerous single-center reports and meta-analyses, few studies have directly compared outcomes of LSG with versus without concomitant cholecystectomy exclusively in a high-risk cohort as defined above.
- Trial name
- NCT07772440
- Volunteers
- 2,512 people
- Sponsor
- Zagazig University