Clinical trials: Laparoscopic Surgery
Rectal Cancer, Colon Cancer
Perfusion Assessment in Laparoscopic Left Anterior Resection
The purpose of this study is to demonstrate that NIR fluorescence angiography using the PINPOINT Endoscopic Fluorescence Imaging System ("PINPOINT System" or "PINPOINT") can assess viability of colon tissue during laparoscopic…
- Conditions
- Rectal Cancer, Colon Cancer, Crohn's Disease, Polyp
- Trial name
- PILLAR II (NCT01560377)
- Testing
- PINPOINT Endoscopic Fluorescence Imaging System
- Where
- 11 sites in United States
- Volunteers
- 147 people
- Sponsor
- Novadaq Technologies ULC, now a part of Stryker
Surgical Conditions
Effect of Deep Versus Moderate Neuromuscular Block During Sevoflurane Anesthesia on Intraoperative Surgical Conditions.
A deep neuromuscular block (NMB) is often associated with improved surgical conditions especially in laparoscopic surgery. We previously showed that deep NMB is superior to a moderate NMB under propofol anesthesia.
- Trial name
- BLISS4 (NCT03170661)
- Testing
- Deep neuromuscular block
- Where
- Netherlands
- Volunteers
- 98 people
- Sponsor
- Leiden University Medical Center
Intraoperative Complications, Postoperative Complications
Hemodynamic and Respiratory Variations During Laparoscopic Surgery With and Without Deep Neuromuscular Blockade.
The goal of this study is to investigate the effect of depth of neuromuscular block (NMB) on global and regional (dependent versus nondependent) respiratory mechanics during laparoscopic surgery.
- Conditions
- Intraoperative Complications, Postoperative Complications, Laparoscopy, Surgical Complications From General Anesthesia
- Trial name
- NCT02025075
- Testing
- Rocuronium
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Surgical Conditions
Effect of Deep Neuromuscular Block on Surgical Conditions in Morbidly Obese Patients
This is a randomized control trial (RCT) that studies the surgical conditions during moderate and deep neuromuscular blockade in 100 morbidly obese patients receiving elective laparoscopic surgery for bariatric surgery.
- Trial name
- BLISS3 (NCT02553629)
- Testing
- Rocuronium
- Where
- 2 sites in Netherlands
- Volunteers
- 109 people
- Sponsor
- Leiden University Medical Center
Gallbladder Disease
SILS™ Port Laparoscopic Cholecystectomy Post Market Study
The objectives of this trial are: 1. to assess the feasibility and safety of performing SILS™ Port Laparoscopic Cholecystectomy 2.
- Trial name
- NCT00832767
- Testing
- SILS™ port laparoscopic cholecystectomy, Four Port Laparoscopic Cholecystectomy
- Where
- 10 sites in United States, Italy and 1 more
- Volunteers
- 202 people
- Sponsor
- Medtronic - MITG
Obesity, Laparoscopic Gastric Bypass Surgery
CURES: The Effect of Deep Curarisation and Reversal With Sugammadex on Surgical Conditions and Perioperative Morbidity
The purpose of this study is to investigate if a deep neuromuscular block with a continuous infusion of rocuronium titrated to a post-tetanic count (PTC) of 1-2 responses combined with reversal of neuromuscular blockade with…
- Conditions
- Obesity, Laparoscopic Gastric Bypass Surgery, Surgical Conditions, Respiratory Function
- Trial name
- CURES (NCT01748643)
- Testing
- deep neuromuscular blockade with rocuronium, reversal with sugammadex, normal neuromuscular blockade reversal with rocuronium, reversal with neostigmine
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- Ziekenhuis Oost-Limburg
Laparoscopy, Anesthesia Recovery Period
Deep Neuromuscular Block for Laparoscopic Surgery
Trial summary: deep neuromuscular block is proposed as a technique to improve operative conditions for laparoscopy. Early clinical data would suggest that there may also be patient benefits beyond the operative period related to…
- Trial name
- DEEPBLOCK (NCT03034577)
- Testing
- Sugammadex, Neostigmine
- Where
- 4 sites in Australia
- Volunteers
- 350 people
- Sponsor
- University of Melbourne
Obesity, DM
Lap-Band Surgery on Adolescents for Safety and Efficacy
This study is to demonstrate the safety and efficacy of the use of the LAP-BAND surgery in the morbidly obese adolescent population.
- Trial name
- ALAGB (NCT00587301)
- Testing
- Lap-Band
- Where
- United States
- Volunteers
- 119 people
- Sponsor
- NYU Langone Health
Postoperative Pain, Abdominal Surgery
Bupivacaine Effectiveness and Safety in SABER® Trial
This is a research study testing SABER-Bupivacaine (an experimental pain-relieving medication). SABER-Bupivacaine is designed to continuously deliver bupivacaine, a common local anesthetic, for a few days in order to treat local…
- Trial name
- BESST (NCT01052012)
- Testing
- SABER-Bupivacaine, Bupivacaine HCl
- Where
- 26 sites in United States, Australia and 1 more
- Volunteers
- 331 people
- Sponsor
- Durect
Hysterectomy
A Trial on Laparoscopic Hysterectomy Versus Robotic Hysterectomy
Robotic technology has been used for laparoscopic hysterectomies for over 10 years. Mayo Clinic Arizona has used robotics in Gynecology for the last 10 years with well over 500 procedures performed.
- Trial name
- NCT00895284
- Testing
- Robotic hysterectomy, Standard Hysterectomy
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Mayo Clinic
Fatigue
Bundling and Unbundling the Laparoscopic Electrosurgery Cord With the Camera Cord
Electrosurgery is used in virtually every laparoscopic operation performed. Capacitive coupling is a common electrosurgery complication.
- Trial name
- NCT01707095
- Testing
- Unbundling of cords, Bundling of cords
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Appendicitis
Single-incision Laparoscopic (SILS) Versus Conventional Laparoscopic Appendectomy for the Treatment of Acute Appendicitis
Recent advances in laparoscopic instrumentation have made it possible to perform intra-abdominal operations entirely through a small incision that can be hidden within the umbilicus.
- Trial name
- NCT00997516
- Testing
- SILS appendectomy, conventional laparoscopic appendectomy
- Where
- 2 sites in United States
- Volunteers
- 75 people
- Sponsor
- University of California, San Francisco
Morbid Obesity, Obstructive Sleep Apnea Syndrome
LAGB as a Treatment for Morbid Obesity in Adolescents
Laparoscopic adjustable gastric banding (LAGB) has been used worldwide to help selected morbidly obese adults to lose weight. The FDA has approved LAGB only for patients 18 years or older.
- Conditions
- Morbid Obesity, Obstructive Sleep Apnea Syndrome, Metabolic Syndrome, Insulin Resistance
- Trial name
- NCT01045499
- Testing
- Laparoscopic adjustable gastric banding (Allergan Lap Band)
- Where
- United States
- Volunteers
- 137 people
- Sponsor
- Jeffrey L Zitsman, MD
Pelvic Organ Prolapse, Abdominal Surgery
The Effect of Abdominal Binder Use on Postoperative Pain and Mobility in Patients Undergoing Pelvic Surgery
To determine the effect of post-operative abdominal binder usage on total narcotic usage after undergoing surgery. To determine if abdominal binder usage results in decreased visual analog scale (VAS) pain scores and shorter time…
- Conditions
- Pelvic Organ Prolapse, Abdominal Surgery, Laparoscopic Surgery, Post Operative Pain
- Trial name
- NCT03684304
- Testing
- Abdominal binder
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Neuromuscular Blockade
The Effect of Deep Neuromuscular Block on Surgical Condition During Laparoscopic Colorectal Surgery
This study is a randomized, controlled, double-blinded, and parallel design study. A total 96 patients were randomized to receive a deep block or a moderate block scheduled for elective laparoscopic colorectal surgery.
- Trial name
- DEEPCOL (NCT02580188)
- Testing
- sugammadex
- Volunteers
- 70 people
- Sponsor
- Seoul National University Bundang Hospital