Clinical trials: Laparoscopic Surgical Procedures
Laparoscopic Surgery, Intraocular Pressure
The Effect of the Steep Trendelenburg Position on Intraocular Pressure
A total of 50 patients aged between 18-60 years, classified as American Society of Anesthesiologists (ASA) I-II, undergoing elective total laparoscopic hysterectomy in the steep trendelenburg position (STP) will be included in…
- Trial name
- NCT06440642
- Testing
- tonopen
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Ectopic Pregnancy
Methotrexate Treatment in Cases of Ectopic Pregnancy With Relative Contraindications
Study Description (For Patients, Families, and Healthcare Providers) Purpose: The aim of this study is to evaluate the effectiveness and safety of methotrexate treatment in women with ectopic pregnancy who belong to a group for…
- Trial name
- NCT07186127
- Testing
- Drug: Methotrexate (MTX) Patients received methotrexate treatment according to institutional protocols. Dosage and administration routes were recorded retrospectively. For patients who did not respond
- Where
- Turkey (Türkiye)
- Volunteers
- 230 people
- Sponsor
- Bagcilar Training and Research Hospital
Colon Cancer
Intracorporeal Anastomosis Versus Extracorporeal Anastomosis for Left Colon Cancer
This study aims to investigate the effects of intracorporeal anastomosis and extracorporeal anastomosis in laparoscopic-assisted radical left hemicolectomy on surgical site infection.
- Trial name
- NCT04201717
- Testing
- laparoscopic assisted left colectomy (extracorporeal anastomosis group), total laparoscopic left colectomy (intracorporeal anastomosis group)
- Where
- 12 sites in China
- Volunteers
- 350 people
- Sponsor
- Jilin University
Colorectal Cancer
Safety and Feasibility of Laparoscopic Intracorporeal Anastomosis for Colorectal Surgery- A Multiple Center Real World Study
The goal of this observational study is to explore the safety and feasibility of laparoscopic intracorporeal anastomosis in colorectal cancer surgery. The main questions it aims to answer are: 1.
- Trial name
- SELECTED (NCT05911152)
- Testing
- Intracorporeal anastomosis
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Intracranial Pressure Increase
Do Extraperitoneal Laparoscopic Surgeries Increase Intracranial Pressure?
When the literature is examined, it has been reported in many studies that intracranial pressure increases due to laparoscopic procedures performed in the intraperitoneal area.
- Trial name
- NCT05668208
- Testing
- E-CUBE i7 ultrasound system (Alpinion Medical Systems, Seoul, Republic of Korea)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Konya City Hospital
Gastric Perforation
Comparison of Laparoscopic Surgery and Open Surgery for Repair of Gastric Perforation
Gastric perforation (GP) is a penetrating lesion of the gastric wall that accounts for 10-15% of all peptic ulcer perforations, and most GP are spontaneous perforations caused by ulcer disease.
- Trial name
- NCT06870604
- Testing
- do open surgery, do laparoscopic surgery
- Volunteers
- 827 people
- Sponsor
- Dong Peng
Colorectal Cancer
Robotic Versus Laparoscopy NOSE for Stage I-III Left-sided Colon Cancer
In this project, the investigator aims to provide the level 1 evidence for the comparison of robotic versus laparoscopic NOSE for the surgery of stage I-III colorectal cancer.
- Trial name
- NCT05970133
- Testing
- Colectomy with NOSE procedure
- Where
- Taiwan
- Volunteers
- 300 people
- Sponsor
- National Taiwan University Hospital
Music Therapy, Cholecystitis/Cholelithiasis
Effect of Preoperative Music on Sterile Inflammation Induced by Laparoscopic Surgery
Surgery induced sterile inflammation leaves behind a biomolecular footprint measurable by various pro-inflammatory markers e.g. IL-6, CD(Cluster of differentiation)19B, HsCRP(High-sensitivity CRP) etc.
- Conditions
- Music Therapy, Cholecystitis/Cholelithiasis, Inflammatory Response, Surgical Injury
- Trial name
- NCT03429478
- Testing
- Preoperative application of a bluetooth enabled Headphones.
- Where
- India
- Volunteers
- 50 people
- Sponsor
- Sir Ganga Ram Hospital
C.Delivery; Surgery (Previous), Gynecological, Inappropriate Device Stimulation of Tissue
The Effect of TEAS on the Quality of Early Recovery
During the past four decades, gynecologic laparoscopy has evolved from a limited method to an advanced operative approach that frequently serves as a substitute for laparotomy.
- Conditions
- C.Delivery; Surgery (Previous), Gynecological, Inappropriate Device Stimulation of Tissue, Delayed Emergence From Anesthesia
- Trial name
- NCT02619578
- Testing
- TEAS, Con, propofol, remifentanil, vecuronium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Guizhou Provincial People's Hospital
Laparoscopic Surgery, Visceral Pain, Postoperative
Anrikefon-based Patient-controlled Intravenous Analgesia After Laparoscopic Surgery
Visceral pain following laparoscopic surgery is frequently underestimated, yet it is associated with a range of adverse outcomes.
- Conditions
- Laparoscopic Surgery, Visceral Pain, Postoperative, Anrikefon, Patient-controlled Intravenous Analgesia
- Trial name
- NCT07246785
- Testing
- High-dose anrikefon, Medium-dose anrikefon, Low-dose anrikefon
- Where
- China
- Volunteers
- 13 people
- Sponsor
- Peking University First Hospital
Postoperative Ileus
Electroacupuncture for Postoperative Ileus After Laparoscopic Colorectal Surgery
Postoperative ileus remains a significant medical problem after colorectal surgery that adversely influences patients' recovery and prolongs hospital stay.
- Trial name
- NCT00464425
- Testing
- Electroacupuncture, No Acupuncture
- Where
- China
- Volunteers
- 165 people
- Sponsor
- Chinese University of Hong Kong
Pelvic Organ Prolapse (POP), Synthetic Mesh
Safety and Performance of a Pelvic Floor Mesh Implant for Laparoscopic Sacrocolpopexy (ProGYNious)
The purpose of this clinical investigation is to collect clinical data about the ProGYNious Mesh based on a prospective clinical investigation.
- Conditions
- Pelvic Organ Prolapse (POP), Synthetic Mesh, Laparoscopic Surgery, Gynecologic Laparoscopic Surgery
- Trial name
- ProGYNious (NCT07497321)
- Testing
- Surgical mesh for pelvic organ prolapse repair (ProGYNious)
- Where
- 4 sites in Austria, Germany
- Volunteers
- 100 people
- Sponsor
- A.M.I. Agency for Medical Innovations GmbH
Hernia
Part vs Whole Task Mastery Training for Laparoscopic Hernia Repair
The investigators will perform a randomized controlled trial with a stratified-block design to compare the effect of the part versus whole task simulation training for TEP repairs.
- Trial name
- NCT01629485
- Testing
- Online Video Curriculum, Whole Task Mastery Training, Part Task Mastery Training
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Laparoscopic Surgery, Gynecology
Atropine in Laparoscopic Gynaecological Surgery
This is a double blinded, randomised controlled trial that will compare atropine to placebo for postoperative pain in laparoscopic gynaecological surgery
- Trial name
- ALGOS (NCT02769325)
- Testing
- Atropine, Sevoflurane, sugammadex
- Where
- Chile
- Volunteers
- 150 people
- Sponsor
- Clinica Santa Maria
Intracranial Pressure Increase, Abdominal Pain
Different Intraperitoneal Pressures on Optic Nerve Sheath Diameter in Laparoscopic Surgeries
The aim of this study is to investigate the effects of low and normal intraperitoneal pressures on intraoperative optic nerve sheath diameter in laparoscopic gyneco-oncologic surgeries.
- Conditions
- Intracranial Pressure Increase, Abdominal Pain, Head Pain
- Trial name
- NCT07155109
- Testing
- Low pressure group, Normal pressure group
- Where
- Turkey (Türkiye)
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Post Operative Nausea and Vomiting (PONV)
Efficacy of Adding Oral Amisulpride to Dual Prophylaxis for Postoperative Nausea and Vomiting in Patients at High Risk for Nausea and Vomiting Undergoing Gynecological Surgery
Amisulpride is a potent antagonist of dopamine D2 and D3 receptors, both implicated in the emetic response when activated. It is currently used intravenously for the prevention of chemotherapy-induced and postoperative nausea and…
- Trial name
- NCT06887621
- Testing
- Encapsulated amisulpride 50 mg (matched for color, weight, smell and size)
- Where
- Brazil
- Volunteers
- 276 people
- Sponsor
- Instituto do Cancer do Estado de São Paulo
Laparoscopic Surgery, Trendelenburg Position
Trend Correlation Between End-Tidal and Arterial Carbon Dioxide During Laparoscopic Surgery in Trendelenburg Position
In this study, we want to find out whether a person's "end-tidal carbon dioxide" (ETCO₂)-a value measured from the air they breathe out-accurately reflects the amount of carbon dioxide in their blood, called "arterial carbon…
- Trial name
- NCT06838078
- Volunteers
- 79 people
- Sponsor
- Koç University
Opioid Consumption, Postoperative, Multimodal Analgesia
Robotic Opioid-free Prostatectomy Enhanced Strategy (ROPES)
This prospective, interventional, open-label, phase 3 randomized study evaluates a multimodal analgesia discharge pathway to reduce automatic opioid prescribing following routine robotic-assisted laparoscopic prostatectomy…
- Conditions
- Opioid Consumption, Postoperative, Multimodal Analgesia, Robotic Assisted Laparoscopic Surgery, Robotic Assisted Laparoscopic Radical Prostatectomy
- Trial name
- ROPES (NCT07427043)
- Testing
- multimodal analgesia pathway with up-front small opioid prescription, multimodal analgesia pathway without up-front small opioid prescription, pre-implementation baseline including opioid
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- Brigham and Women's Hospital
Rectal Cancer, Adenocarcinoma
Prospective Randomized Study of SILS Versus CLS for Rectal Cancer
Background: Single-port laparoscopic surgery is emerging as a method to improve morbidity and cosmetic benefits of conventional laparoscopic surgery and minimize the surgical trauma.
- Trial name
- NCT01579721
- Testing
- Single Incision Laparoscopic Surgery
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Hvidovre University Hospital
Evaluation of Expected Bone Loss After Bariatric Surgery, Possible Prevention of Bone Loss After Surgery by Calcium and Vitamin D Supplementation
Bone Metabolism After Laparoscopic Gastric Bypass Surgery (BABS)
Bariatric surgery leads to rapid weight loss in female and male patients. Less data are available about its impact on bone metabolism.
- Trial name
- BABS (NCT01739855)
- Testing
- Calciferol, calcium carbonate
- Where
- Austria
- Volunteers
- 160 people
- Sponsor
- Medical University of Vienna
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