Clinical trials: Laparoscopy-assisted Surgery
Malignant Neoplasm of Transverse Colon, Malignant Neoplasm of Descending Colon
Randomized Controlled Trial Between Laparoscopic and Open Surgery in Transverse and Descending Colon Cancer Patients
The long-term results of several large-scale prospective randomized trials that compared laparoscopic-assisted and open colectomy for colon cancer were published in the past decade.
- Trial name
- NCT01861691
- Testing
- Open surgery, Laparoscopic surgery
- Where
- Japan
- Volunteers
- 66 people
- Sponsor
- Shoichi Fujii, MD, PhD
Kolon Kanseri
Erector Spinae Plane Block in Laparoscopic Colorectal Cancer Surgery
Our study will compare patients who underwent laparoscopic surgery for colorectal cancer with and without Erector Spinae Plane Block in terms of renal blood flow and renal function tests.
- Trial name
- NCT07297433
- Testing
- Erector Spinae Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Kayseri City Hospital
Abdominal Hernia, Abdominal Surgery
Versius or Laparoscopic Abdominal Hernia REpair
This trial will compare laparoscopic and robotic-assisted abdominal hernia repairs, using the Versius® system. We will initially aim to recruit 60 patients (20 patients in the laparoscopic arm and 40 in the robotic arm) in order…
- Trial name
- VOLARE (NCT05253586)
- Testing
- Laparoscopic, Robotic
- Sponsor
- Joanne Turner
Locally Advanced Rectal Cancer, Abdominoperineal Resection
Inflammation After Laparoscopic Robot-assisted Surgery for Locally Advanced Rectal Cancer
The intention of the study is to explore metabolic and inflammatory parameters in the pelvis and systemically after abdominoperineal resection (APR) for locally advanced rectal cancer (LARC) in patients that have received…
- Trial name
- APR-IMM (NCT04324567)
- Where
- Norway
- Volunteers
- 55 people
- Sponsor
- Oslo University Hospital
Laparoscopic Surgery
The Use of Tidal Volume Challenge of Dynamic Parameters During Laparoscopic Surgery
Laparoscopy is increasingly used for major abdominal and pelvic surgery. As this approach is also recommended in elderly patients with serious comorbidities, optimal fluid therapy guidance during this procedure is important.
- Trial name
- NCT03467711
- Testing
- tidal volume challenge, volume expansion
- Where
- South Korea
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Hallym University Kangnam Sacred Heart Hospital
Airway Management, Supraglottic Airway
I-gel Plus Supraglottic Airway Device for Elective Laparoscopic Surgery
i-gel Plus is a novel supraglottic airway device (SGA). Feasibility of second-generation SGAs in patients undergoing elective laparoscopic surgery has been demonstrated in various studies.
- Conditions
- Airway Management, Supraglottic Airway, General Anesthesia, Laparoscopic Surgery
- Trial name
- NCT06602830
- Where
- Germany
- Volunteers
- 48 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Renal Cell Carcinoma
Transperitoneal vs Retroperitoneal Laparoscopic or Robotic Partial Nephrectomy
Both laparoscopic partial nephrectomy (LPN) and robotic partial nephrectomy (RPN) can be performed through transperitoneal (TP) or retroperitoneal (RP) approach.
- Trial name
- NCT02849119
- Testing
- Laparoscopic or robotic partial nephrectomy
- Where
- South Korea
- Volunteers
- 106 people
- Sponsor
- Samsung Medical Center
Gallbladder Disease
SILS™ Port Laparoscopic Cholecystectomy Post Market Study
The objectives of this trial are: 1. to assess the feasibility and safety of performing SILS™ Port Laparoscopic Cholecystectomy 2.
- Trial name
- NCT00832767
- Testing
- SILS™ port laparoscopic cholecystectomy, Four Port Laparoscopic Cholecystectomy
- Where
- 10 sites in United States, Italy and 1 more
- Volunteers
- 202 people
- Sponsor
- Medtronic - MITG
Shoulder Pain, Laparoscopic Surgery
Reducing Shoulder Tip Pain Following Laparoscopic Surgery
Laparoscopic surgery is becoming a major procedure, owing to smaller incisions, shorter hospitalizations, and less post-operative pain as compared with traditional laparotomies.
- Trial name
- NCT01135836
- Testing
- Pulmonary recruitment maneuver, Intraperitoneal normal saline, Control group
- Where
- Taiwan
- Volunteers
- 180 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
mERAS Intervention, The ASA (American Society of Anesthesiologists) Score
The Contribution of Accelerated Recovery (mERAS) Approach to Postoperative Recovery in Pediatric Laparoscopic Surgery Cases
Pediatric laparoscopic surgery is a gold standard across all ages, offering benefits like smaller incisions, faster recovery, and better cosmetic outcomes.
- Conditions
- mERAS Intervention, The ASA (American Society of Anesthesiologists) Score, The Patient Must be Between 4 and 12 Years Old
- Trial name
- Accelerated Re (NCT07375511)
- Testing
- mERAS Protocol
- Volunteers
- 60 people
- Sponsor
- Emel Yürük
Adhesive Small Bowel Obstruction
Comparison of Laparoscopic Surgery Versus Open Surgery in the Treatment of Adhesive Small Bowel Obstruction
Small bowel obstruction is a common reason for surgical admission. Most common reason for small bowel obstruction is adhesions, which account up to 70-80 % of small bowel obstructions.
- Trial name
- NCT01867528
- Testing
- Laparoscopic adhesiolysis, Open adhesiolysis
- Where
- 8 sites in Finland, Italy
- Volunteers
- 102 people
- Sponsor
- Helsinki University Central Hospital
Atelectasis
Role of Lung Ultrasound Imaging for Intraoperative Monitoring of Atelectasis During Laparoscopic Surgery
General anesthesia results in the development of atelectasis in the dependent areas of the lungs exposing patients to an increased risk of hypoxemia.
- Trial name
- NCT01749436
- Testing
- Lung ultrasound imaging examinations
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Colorectal Cancer
Comparison of NOSES and Conventional Laparoscopic Surgery in Colorectal Cancer
Radical surgery for rectal cancer has evolved from the initial concept of total mesorctal excision (TME) to the wide application of laparoscopic surgery in the radical treatment of rectal cancer.
- Trial name
- NCT04559087
- Testing
- Laparoscopic Surgery
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Zunyi Medical College
Colonic Neoplasms, Crohn's Disease
Single Port Colic Laparoscopic Surgery
This study aims to compare the results of colonic surgery performed by single and multiport laparoscopy.
- Conditions
- Colonic Neoplasms, Crohn's Disease, Diverticulitis
- Trial name
- TRUE (NCT01959087)
- Testing
- single port surgery, Multiport surgery
- Where
- France
- Volunteers
- 128 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Fluid Responsiveness
Pressure Gradient for Venous Return in Predicting Fluid Responsiveness in Patients Undergoing Laparoscopic Surgery
Surgical patients, especially those with insufficient blood volume and hypotension, often need fluid therapy. However, there is still a lack of simple and reliable indicators for judging transfusion responsiveness in some types…
- Trial name
- NCT04030221
- Testing
- fluid infusion
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Stomach Neoplasms, Minimally Invasive Surgery
Intracorporeal Versus Extracorporeal Roux-en-Y Esophagojejunostomy During Laparoscopic Total Gastrectomy for Gastric Cancer
To date, Roux-en-Y esophagojejunostomy transabdominal extracorporeally by circular stapler was the most common used method during laparoscopy-assisted total gastrectomy for gastric cancer, even though it was not totally…
- Conditions
- Stomach Neoplasms, Minimally Invasive Surgery, Anastomosis
- Trial name
- NCT02085031
- Testing
- Intracorporeal Roux-en-Y esophagojejunostomy, Extracorporeal Roux-en-Y esophagojejunostomy
- Where
- China
- Volunteers
- 136 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Electrical Impedance Tomography
PEEP Titration Guided by Electrical Impedance Tomography in Laparoscopic Surgery The PEaRL Study
Background: Laparoscopic surgery has gained widespread adoption due to its minimally invasive nature, offering advantages such as reduced postoperative pain, shorter hospitalization, and faster functional recovery compared with…
- Trial name
- PEaRL (NCT07289113)
- Testing
- A PEEP trial performed with the PulmoVista® 500 (Dräger, Lübeck, Germany) is a procedure designed to identify the optimal level of positive end-expiratory pressure
- Where
- Italy
- Volunteers
- 52 people
- Sponsor
- ASST Fatebenefratelli Sacco
Residual Neuromuscular Block, Cardiovascular Diseases
Effects of Low-pressure Pneumoperitoneum Associated With Deep Pipecuronium-induced Neuromuscular Blockade on Hemodynamic Parameters for High Cardiovascular Risk Patient Undergoing General Anesthesia
Deep neuromuscular block (DNMB) during laparoscopy induces less haemodynamic stress by facilitating low-pressure pneumoperitoneum.
- Conditions
- Residual Neuromuscular Block, Cardiovascular Diseases, Neuromuscular Blockade Monitoring
- Trial name
- NCT06517524
- Where
- Hungary
- Volunteers
- 10 people
- Sponsor
- Tamas Vegh, MD
Postoperative Pain, Opioid Consumption
Comparison of TAP Block and Umbilical Paramedian Linea Semilunaris Block in Pediatric Laparoscopic Surgery
The aim of this prospective randomized controlled trial is to compare the postoperative analgesic efficacy of ultrasound-guided transversus abdominis plane (TAP) block and umbilical paramedian linea semilunaris block in pediatric…
- Trial name
- NCT07801794
- Testing
- Ultrasound-Guided Transversus Abdominis Plane Block, Ultrasound-Guided Linea Semilunaris Block
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Laparoscopic Surgery, Pneumoperitoneum
Low-pressure vs Standard-pressure in Laparoscopic Cholecystectomy
Background. Many studies have demonstrated reduced postoperative pain in patients undergoing lower pneumoperitoneum pressure level during laparoscopic cholecystectomy.
- Conditions
- Laparoscopic Surgery, Pneumoperitoneum, Cholecystitis; Choledocholithiasis, Quality of Life
- Trial name
- NCT04146090
- Testing
- Low-pressure pneumoperitoneum, Standard pressure pneumoperitoneum
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Pontificia Universidade Catolica de Sao Paulo