Clinical trials: Large Infarct Core
Basilar Artery Occlusion, Large Ischemic Core
EVT in Acute Basilar Artery Occlusion With Large Infarction Core
A multicenter, prospective, open-label, blinded endpoint, randomized controlled trial designed to evaluate the efficacy and safety of best medical management (BMM) combined with endovascular treatment (EVT) versus BMM alone in…
- Conditions
- Basilar Artery Occlusion, Large Ischemic Core, Large Core Infarct, Endovascular Treatments
- Trial name
- BOLT (NCT07090941)
- Testing
- Endovascular Treatment
- Where
- 2 sites in China
- Volunteers
- 372 people
- Sponsor
- The First Affiliated Hospital of Hainan Medical University
Basilar Artery Occlusion, Ischemic Stroke
Basilar Artery Occlusion Chinese Endovascular Registry in Patients With Large-Core Infarct
This multicenter retrospective registry study evaluates the safety and effectiveness of endovascular therapy versus medical therapy for acute large-core basilar artery occlusion.
- Conditions
- Basilar Artery Occlusion, Ischemic Stroke, Large Core Infarct
- Trial name
- BAOCHE-LC (NCT07345702)
- Testing
- Endovascular Therapy
- Where
- China
- Volunteers
- 518 people
- Sponsor
- Xuanwu Hospital, Beijing
Acute Ischemic Stroke, Large Infarct Core
Methylprednisolone Adjunctive to Endovascular Thrombectomy for Stroke
The efficacy and safety of methylprednisolone in acute ischemic stroke patients with large infarct cores (ASPECTS score < 6 or infarct volume ≥50 mL) due to anterior circulation large vessel occlusion have not been clearly…
- Trial name
- MIRACLE (NCT06360458)
- Testing
- Methylprednisolone sodium succinate
- Where
- 99 sites in China
- Volunteers
- 928 people
- Sponsor
- Wan-Jin Chen
Large Infarct Core, Post-stroke Lymphocytopenia
Methylprednisolone for Stroke With Large Infarct Core and Post-stroke Lymphocytopenia
The efficacy and safety of early adjunctive methylprednisolone therapy in acute ischemic stroke patients with large infarct cores (ASPECTS score < 6) and post-stroke lymphocytopenia remain unclear.
- Trial name
- MIRACLE-2 (NCT07202143)
- Testing
- Methylprednisolone sodium succinate, Normal Saline
- Where
- China
- Volunteers
- 200 people
- Sponsor
- YiLin
Basilar Artery Occlusion, Ischemic Stroke
Basilar Artery Occlusion Chinese Endovascular Trial in Patients With Large Core Infarct
This study evaluates the safety and efficacy of endovascular therapy for acute basilar artery occlusion with large core infarcts in a multicenter randomized trial.
- Conditions
- Basilar Artery Occlusion, Ischemic Stroke, Large Core Infarct
- Trial name
- BAOCHE3 (NCT07046299)
- Testing
- Endovascular Therapy Plus Best Medical Treatment, Best Medical Treatment Alone
- Where
- China
- Volunteers
- 314 people
- Sponsor
- Capital Medical University