Clinical trials: Large Language Models, open to volunteers
Breast Neoplasms, Lung Neoplasms
Benchmarking Large Language Models Against Tumour Boards for Oncology Treatment Recommendations
BEACON (Benchmarking AI for Clinical Oncology decisioNmaking) is a prospective, multicentre, comparative, blinded, non-interventional benchmark comparing the treatment recommendations of six frontier large language models (LLMs)…
- Conditions
- Breast Neoplasms, Lung Neoplasms, Urologic Neoplasms, Prostatic Neoplasms
- Trial name
- BEACON (NCT07739121)
- Testing
- Multidisciplinary tumour boards, Frontier large language models
- Where
- 5 sites in France
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Large Language Model
Evaluating the Acceptability of AI-Personalized Virtual Reality Picture Books for Hospitalized Pediatric Patients
Hospitalization strips pediatric patients of the environments, objects, and people that shape their daily lives. Hospitalized pediatric patients routinely experience painful procedures, psychological distress, boredom, and a…
- Trial name
- LLM-audiobook (NCT07637617)
- Testing
- LLM-audiobook
- Volunteers
- 15 people
- Sponsor
- Stanford University
Radiography, Oral Health
Large Language Models for Dental Radiology Report Generation From Structured Textual Data
The purpose of this observational methodological study is to evaluate whether large language models can transform structured dental radiology data into clear narrative radiology reports.
- Conditions
- Radiography, Oral Health, Large Language Model, Natural Language Processing (NLP)
- Trial name
- DENT-LLM (NCT07676318)
- Testing
- Large language model-assisted radiology report generation
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Hospital of the Ministry of Interior, Kielce, Poland
AI-Assisted Diagnosis, Large Language Models
Improving AI-Assisted Medical Diagnosis and Triage by the General Public
This study is a randomized controlled trial (RCT) investigating whether access to a new LLM interface can improve medical triage and diagnostic accuracy for laypeople compared to access to a standard LLM interface.
- Trial name
- NCT07728513
- Testing
- new GPT-4o Interface, Control
- Where
- Pakistan
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Lahore University of Management Sciences
Chatbot, Large Language Model
Effects of a Large Language Model-Driven Chatbot on Reproductive Concerns After Cancer
Reproductive health has emerged as a critical yet overlooked concern among Adolescent and Young Adult (AYA) cancer survivors, given their compromised potential for biological parenthood in prime childbearing years.
- Conditions
- Chatbot, Large Language Model, Adolescent and Young Adult Cancer Survivors, Reproductive Health
- Trial name
- NCT07741266
- Testing
- Chatbot, Electronic brochure
- Where
- 2 sites in China, Hong Kong
- Volunteers
- 60 people
- Sponsor
- The Hong Kong Polytechnic University
Peritoneal Dialysis (PD), Large Language Models
A Simulated Case Study of a Peritoneal Dialysis-Specialized Large Language Model Assisting Doctors in Improving Decision-Making in Peritoneal Dialysis Management
This study is a randomized controlled trial based on simulated clinical cases, aiming to establish a standardized evaluation system for PD physicians, to assess the differences in PD management quality between a workflow assisted…
- Trial name
- NCT07724327
- Testing
- Peritoneal dialysis-specialized large language model.
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Thyroid Cancer, Large Language Models
Evaluation of an Artificial Intelligence-enabled Clinical Assistant to Support Thyroid Cancer Management
This study aims to evaluate the clinical feasibility of adopting artificial intelligence (AI)-based models to improve clinical management of thyroid cancer.
- Trial name
- NCT07234539
- Testing
- AI-enabled clinical assistant
- Where
- 2 sites in Hong Kong
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Peritoneal Dialysis (PD), Large Language Models
Peritoneal Dialysis (PD) Specialized LLM for PD Management
This study conducted a randomized controlled trial using clinical vignettes to evaluate differences in the quality of PD management among two large language model-assisted workflows and a physician-only decision-making process…
- Trial name
- PIONEER-PD (NCT07539428)
- Testing
- Peritoneal dialysis-specialized large language model., Generalized LLM tools such as deepseek
- Where
- China
- Volunteers
- 150 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Ophthalmic Disease, Artifical Intelligence
Evaluating AI-Generated Plain Language Summaries on Patient Comprehension of Ophthalmology Notes Among English-Speaking Patients
This clinical trial is testing whether plain language summaries made by artificial intelligence help people understand their eye doctor's notes better.
- Conditions
- Ophthalmic Disease, Artifical Intelligence, Large Language Model
- Trial name
- NCT06859216
- Testing
- AI-Generated Plain Language Summaries
- Where
- United States
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Ophthalmology, Large Language Models
A Multimodal AI Agent for Ophthalmic Clinical Decision Support
This study is a multicenter randomized controlled trial evaluating the effectiveness and safety of EyeAgent, a multimodal artificial intelligence (AI) agent designed to assist ophthalmologists in clinical decision-making.
- Conditions
- Ophthalmology, Large Language Models, AI Agent, Eye Disease
- Trial name
- NCT07401459
- Testing
- EyeAgent AI system
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University