Clinical trials: Large Renal Stone
Renal Stones, Retrograde Intrarenal Surgery
Safety of Thulium Fiber Laser Litothripsy in the Management of Large Renal Stones (>1000 mm³) and Factors Affecting Treatment Success
The aim of this study is to compare the efficacy and safety of Thulium Fiber Laser (TFL) litothripsy according to stone density and the factors affecting success in patients undergoing retrograde intrarenal surgery (RIRS) for…
- Conditions
- Renal Stones, Retrograde Intrarenal Surgery, Thulium Fiber Laser
- Trial name
- RIRS and TFL (NCT07153978)
- Testing
- Effectivity of TFL on large renal stone
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people
- Sponsor
- Muharrem Baturu
Kidney Calculi
Flexible Ureteroscopy for Large Renal Stones in Children
This prospective single-arm interventional study evaluated the efficacy and safety of flexible ureteroscopy for the treatment of large renal stones measuring 2 cm or more in pediatric patients.
- Trial name
- NCT07780409
- Testing
- Flexible Ureteroscopic Stone Disintegration
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Cairo University
Renal Stones, Renal Calculi > 2 cm
Efficacy & Safety of High Power vs. Low Power Holmium Laser in Mini-PCNL for Large Renal Stones
The investigator will compare between holmium laser setting during miniPCNL for renal stones as regard safety \& efficacy
- Trial name
- miniPCNL (NCT07393178)
- Testing
- mini percutaneous nephrolithotomy
- Volunteers
- 70 people
- Sponsor
- Mansoura University
Determine the Efficacy and Safety of SWL in Renal Stones Larger Than 2 cm in Pediatric Age Group
Extracorporeal Shock Wave Lithotripsy for Treatment of Large Pediatric Renal Pelvic Stone Burden More Than 2 cm
Extracorporeal shock wave lithotripsy (SWL) was first described for pediatric nephrolithiasis in 1986; SWL has been a mainstay of treatment for both renal and ureteral calculi in children .
- Trial name
- NCT05293613
- Testing
- extracorporeal shock wave lithotripsy
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sohag University
Flexible Ureteroscopy, Ureteral Access Sheath
Flexible Ureteroscopy With and Without Ureteral Access Sheath in Treatment of Large Renal Stones
The aim of this study is to evaluate the flexible ureteroscope (FURS) technique with and without ureteral access sheath (UAS).
- Conditions
- Flexible Ureteroscopy, Ureteral Access Sheath, Large Renal Stones
- Trial name
- NCT06122129
- Testing
- Flexible ureteroscope with ureteral access sheath, Flexible ureteroscope without ureteral access sheath
- Where
- Egypt
- Volunteers
- 84 people
- Sponsor
- New Valley University
Large Renal Stone
A Comparative Study Between Anterior and Posterior Pyelotomy in Transperitoneal Laparoscopic Pyelolithotomy
Large renal pelvic stones are frequently managed with percutaneous nephrolithotomy (PCNL) but laparoscopic pyelolithotomy (LPL) can be an alternative procedure when performed by skilled surgeons to achieve excellent outcomes in…
- Trial name
- NCT06394219
- Testing
- traditional transperitoneal laparoscopic pyelolithotomy, modified transperitoneal laparoscopic pyelolithotomy
- Where
- Syria
- Volunteers
- 36 people
- Sponsor
- Damascus University
Stone, Kidney, Stone, Urinary
FANS-FURS vs Suction Mini-PCNL for 2-3 cm Renal Stones: A Multicenter Randomized Trial
This multicenter, prospective, randomized clinical trial compares FANS-assisted flexible ureteroscopy (FURS) with suction-assisted mini-percutaneous nephrolithotomy (mini-PCNL) for the treatment of renal stones measuring 2-3 cm.
- Trial name
- NILE (NCT07295860)
- Testing
- FANS-Based Flexible Ureteroscopy (FURS), Suction-Assisted Mini-PCNL
- Where
- 9 sites in Egypt
- Volunteers
- 254 people
- Sponsor
- Mansoura University
Kidney Calculi
ShockPulse-SE vs. Trilogy Trial: Comparing the Performance of Two Intracorporeal Lithotripters for Removal of Large Renal Calculi
The purpose of this study is to measure how well two different devices work to break up and remove kidney stones. We are comparing a newer device to an older one to see which one is faster at breaking up kidney stones.
- Trial name
- NCT03959683
- Testing
- Trilogy Lithotrite, The ShockPulse-SE Lithotripsy System
- Where
- 4 sites in United States, Canada
- Volunteers
- 100 people
- Sponsor
- Indiana University
Kidney Calculi, Prostatic Hyperplasia
An International Multicenter Clinical Study on Application of UroMed AI Doctor Based on Large Language Models
This study evaluates our team's urology-specific AI (UroMed AI Doctor) for its safety, professionalism, knowledge and Q\&A ability, and tests its effectiveness against traditional manual urology care, to confirm if it can be a…
- Conditions
- Kidney Calculi, Prostatic Hyperplasia, Urinary Bladder Neoplasms
- Trial name
- NCT07555756
- Testing
- UroMed AI Doctor-assisted Urological Diagnosis, Treatment and Preoperative Health Education, Physician-led Urological Diagnosis, Treatment & Preoperative Education
- Where
- 5 sites in China, Vietnam
- Volunteers
- 1,080 people
- Sponsor
- First Affiliated Hospital of Guangxi Medical University
Kidney Stones, Nephrolithiasis
FANS vs CVAC for Medium to Large Stones
Improvements in ureteroscopes have led to improved stone free rates. Two new devices (FANS - Flexible and Navigable Suction) and the CVAC ureteroscope have never been compared head to head.
- Trial name
- NCT07514351
- Testing
- ureteroscopy, CVAC
- Where
- United States
- Volunteers
- 159 people
- Sponsor
- Ohio State University
Stones, Kidney
Endoscopic Guided PCNL Versus Standard PCNL
currently, percutaneous nephrolithotomy (PCNL) is the standard procedure of choice for management of large renal more than 2 cm. the pivotal step in performing PCNL is creation of proper tract.
- Trial name
- NCT04825353
- Testing
- Endoscopic compbined guided PCNL, Standard PCNL
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Benha University
Stone, Kidney
Disposable Versus Disposable Nephroscope During PCNLs: a Feasibility RCT
A feasibility randomised controlled trials comparing re-usable versus disposable nephroscope when treating kidney stones during mini-PCNLs
- Trial name
- NCT06579924
- Testing
- Disposable mini-PCNL, Re-usable mini-PCNL
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Kidney Calculi, Nephrolithiasis
Supine vs. Prone PCNL for Large Renal Stones: A Randomized Trial in Yemen.
The goal of this clinical trial is to compare the safety, cost-effectiveness, and patient recovery of two different surgical positions for percutaneous nephrolithotomy (PCNL) in adults aged 18 to 70 years who have kidney stones…
- Trial name
- NCT07627503
- Testing
- Supine Percutaneous Nephrolithotomy (PCNL), Prone Percutaneous Nephrolithotomy (PCNL)
- Where
- Yemen
- Volunteers
- 140 people
- Sponsor
- Sana'a University
Renal Calculi
Ureteroscopic Laser Modality on Total Lasing Time and Total Energy in Patients With Large, Dense Renal Calculi
This study will examine the effects of ureteroscopic lasing technique (dusting, fragmentation and a hybrid approach) on total lasing time and total energy in patients with a large renal calculi burden of single or multiple stones…
- Trial name
- NCT05869890
- Testing
- MOSES laser system
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Albany Medical College
Staghorn Calculi
Multitract Percutaneous Nephrolithotomy(PCNL) in Large Renal Stones.
Investigator aimed to analyze the clinical efficacy and safety of multiple tracts PCNL as one step therapy to treat the staghorn stones or multiple calyceal calculi which are inaccessible by single tract
- Trial name
- PCNL (NCT05291702)
- Testing
- PCNL
- Volunteers
- 40 people
- Sponsor
- Assiut University
Kidney Stone
Comparing Pneumatic Versus Ultra-sonic Percutaneous Nephrolithotomy in Large Kidney Stones
The purpose of this study is to determine which type of percutaneous nephrolithotomy is better in large kidney stones
- Trial name
- NCT02751281
- Testing
- Pneumatic percutaneous nephrolithotomy, Ultra-sonic percutaneous nephrolithotomy
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Stone, Kidney
Silodosin in Management of Lower Ureteral Stones
This research aims to study the effectiveness of silodosin in the management of lower ureter stones larger than 6 mm in diameter in terms of affected ureter (right or left), the size of the stone, the degree of hydronephrosis…
- Trial name
- NCT06381206
- Testing
- Silodosin
- Where
- Syria
- Volunteers
- 100 people
- Sponsor
- Syrian Private University
Renal Stone
Comparison of Surgical Outcomes Between MPCNL and RIRS
The objective of this research is to investigate the surgical outcomes of minimally invasive percutaneous nephrolithotomy(MPCNL) and retrograde intrarenal surgery (RIRS)for patients with renal stone larger than 1cm.
- Trial name
- NCT02067221
- Testing
- RIRS, MPCNL
- Where
- South Korea
- Volunteers
- 70 people
- Sponsor
- Seoul National University Hospital