Clinical trials: Laryngeal Nerve Injuries
Methylene Blue, Recurrent Laryngeal Nerve Injuries
Methylene Blue Spray for Identification of Recurrent Laryngeal Nerve and Parathyroid Gland
Thyroidectomy is the procedure by which surgeons treat various thyroid diseases and is considered the commonest endocrinal surgery. Yet, it carries a risk for intraoperative complications.
- Conditions
- Methylene Blue, Recurrent Laryngeal Nerve Injuries, Parathyroid Gland
- Trial name
- NCT05113628
- Testing
- methylene blue identification
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Zagazig University
Head and Neck Cancer, Oral Complications
Cevimeline in Treating Patients With Dry Mouth Caused by Radiation Therapy for Head and Neck Cancer
RATIONALE: Cevimeline may be effective in treating dry mouth that is caused by radiation therapy for head and neck cancer. It is not yet known if cevimeline is more effective than no therapy in treating dry mouth caused by…
- Conditions
- Head and Neck Cancer, Oral Complications, Radiation Toxicity
- Trial name
- NCT00017511
- Testing
- cevimeline hydrochloride
- Where
- 71 sites in United States
- Sponsor
- Daiichi Sankyo
Head and Neck Cancer, Long-term Effects Secondary to Cancer Therapy in Adults
Side Effects of High-Dose Intensity-Modulated Radiation Therapy in Treating Patients With Advanced Head and Neck Cancer
RATIONALE: Tests that measure how much saliva is made, hearing, swallowing, voice function, and quality of life may improve the ability to plan treatment for patients with advanced head and neck cancer and may help doctors find…
- Conditions
- Head and Neck Cancer, Long-term Effects Secondary to Cancer Therapy in Adults, Oral Complications of Radiation Therapy, Radiation Toxicity
- Trial name
- NCT00415025
- Testing
- adjuvant therapy, management of therapy complications, quality-of-life assessment
- Volunteers
- 20 people
- Sponsor
- University of Wisconsin, Madison
Esophageal Neoplasm, Anastomotic Leak
Prediction of Anastomotic Complications and Recurrent Laryngeal Nerve Injury Based on Postoperative Early Endoscopic Evaluation
Analyze the correlation between the conformity of the anatomy (based on endoscopic examination) and postoperative anastomotic fistula and anastomotic stenosis; establish an anastomotic classification; and construct a predictive…
- Conditions
- Esophageal Neoplasm, Anastomotic Leak, Recurrent Laryngeal Nerve Injuries, Anastomotic Stenosis
- Trial name
- NCT06348381
- Testing
- No intervention
- Where
- China
- Volunteers
- 250 people
- Sponsor
- Shanghai Chest Hospital
Hip Fracture
Peripheral Nerve Blocks in Elderly Patients With Hip Fracture
As the population ages, the frequency of surgery is increasing proportionally, bringing with it the challenge of managing older patients with frequent comorbid diseases and an increased risk of complications.
- Trial name
- NCT02635763
- Testing
- Femoral nerve and the lateral cutaneous nerve block, Lumbar plexus and sacral plexus nerve block
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Presbylarynx, Aspiration
Assessment of Laryngopharyngeal Sensation: Cancer Survivor Cohort
A previous study completed in 2022 (NCT05158179) was conducted using cohorts of healthy controls, and adults with general laryngopharyngeal disorders.
- Conditions
- Presbylarynx, Aspiration, Spasmodic Dysphonia, Globus Pharyngeus
- Trial name
- NCT06078527
- Testing
- Cheung-Bearelly Aesthesiometer, Transnasal Laryngoscopy, Questionnaires
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of California, San Francisco
Thyroid Diseases, Surgery
NerveTrend vs. i-IONM in Prevention of Recurrent Laryngeal Nerve Events During Bilateral Thyroid Surgery.
The aim of this study is to compare two distinct modes of NIM Vital application in thyroid surgery: i-IONM vs. NerveTrend mode with respect to prevalence of early postoperative RLN injury.
- Conditions
- Thyroid Diseases, Surgery, Recurrent Laryngeal Nerve Injuries
- Trial name
- NCT04794257
- Testing
- Neuromonitoring of the recurrent laryngeal nerves
- Where
- Poland
- Volunteers
- 264 people
- Sponsor
- Marcin Barczynski
Thyroid Diseases, Surgical Injury
Feasibility of Neostigmine for Intraoperative Neuromonitoring in Thyroid Surgery
For successful intraoperative neuromonitoring (IONM), adequate reversal of neuromuscular blocking agent is a prerequisite in thyroid surgery with .
- Conditions
- Thyroid Diseases, Surgical Injury, Nerve Monitoring
- Trial name
- NCT04873531
- Testing
- Neostigmine, Normal saline
- Where
- South Korea
- Volunteers
- 44 people
- Sponsor
- Seoul National University Hospital
Vocal Cord Paralysis, Recurrent Laryngeal Nerve Palsy
Single Dose 4-Aminopyridine for Diagnosing Recurrent Laryngeal Nerve Paralysis Continuity After Trauma
This study aims to evaluate the role of single-dose 4-aminopyridine on the diagnosis of recurrent laryngeal nerve (RLN) paralysis.
- Trial name
- NCT07832331
- Testing
- 4-Aminopyridine
- Volunteers
- 50 people
- Sponsor
- Milton S. Hershey Medical Center
Thyroid Cancer, Recurrent Laryngeal Nerve Injuries
Effect of Reversed Tracking Method for Identification of EBSLN in Thyroid Surgery
The feasibility and effectiveness of Reversed Tracking Method for the identification and protection of extralaryngeal nerve branches in thyroid surgery were analyzed.
- Trial name
- NCT03680222
- Testing
- Reversed Tracking Method
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Fujian Medical University
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
The Coordination of Rare Diseases at Sanford (CoRDS) is an international patient registry that serves as a centralized resource for rare disease research.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Recurrent Laryngeal Nerve Injuries
Recurrent Laryngeal Nerve's Motor Function: Sometimes Motor Fibers May Also Be Located in The Posterior Branch
The investigators hypothesized that, sometimes the posterior branch of the recurrent laryngeal nerve may also have motor function.
- Trial name
- NCT02493881
- Testing
- intraoperative neuromonitoring
- Volunteers
- 337 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital