Clinical trials: Laryngeal Obstruction
Vocal Cord Polyp
The Study of Bilateral Upper Laryngeal Nerve Block for Supporting the Removal of Vocal Cord Polyps Under Laryngoscopy
With the continuous development of microsurgery, supporting laryngoscopy acoustic polyp removal has become a very mature clinical operation.
- Trial name
- NCT05309174
- Testing
- USG-guided iSLN block
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Guizhou Provincial People's Hospital
Asthma Chronic, Vocal Cord Dysfunction
Inducible Laryngeal Obstruction in Severe Asthma in Severe Asthma
The first part will be a comparative cross-sectional study to identify the frequency of ILO and other comorbidites among participants with asthma compared to a group of reference subjects without asthma, matched for age- and…
- Trial name
- NCT04593394
- Testing
- Continous laryngoscopy exercise test, Overnight respiratory polygraphy
- Where
- Norway
- Volunteers
- 116 people
- Sponsor
- Haukeland University Hospital
Airway Obstruction
Effect of Laryngeal Mask Airway on Image Quality n Pediatric Patients Undergoing Magnetic Resonant Imaging
This study compare the effects of Oral airway vs LMA in preventing anesthesia-induced partial airway obstruction, in an attempt to lessen MRI motion artifacts, which would result in improvements in image quality.
- Trial name
- NCT04730362
- Testing
- guedel airway, supraglottic airway, propofol bolus and then anesthesia sevoflurane
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- National Cancer Institute, Egypt
Voice and Resonance Disorders, Vocal Fold Polyp
Efficacy of a Semi-occluded Mask in the Treatment of Patients With Voice Disorders
Current semi-occluded vocal tract therapies limit the type of vocalizations that can be produced to single vowels, which does not promote learning of the healthy voice behavior in connected speech or generalization to…
- Conditions
- Voice and Resonance Disorders, Vocal Fold Polyp, Vocal Cord Cyst, Vocal Cord Polyp
- Trial name
- NCT03410797
- Testing
- Inclusion of semi-occluded mask in voice therapy
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Jacqueline Gartner-Schmidt
Superior Laryngeal Nerve Block, Sedation
Nerve Block Vs Sedation Infusion for Awake Fiberoptic Intubation.
This study compares the efficacy and safety of dexmedetomidine infusion versus superior laryngeal nerve block during awake fiberoptic intubation in hemimandibulectomy patients.
- Conditions
- Superior Laryngeal Nerve Block, Sedation, Dexmedetomidine, Awake Fiberoptic Intubation
- Trial name
- NCT06651905
- Testing
- Dexmedetomidine, Superior laryngeal nerve block
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Cairo University
Cough, Nerve Block
Randomized Placebo-controlled Analysis of Superior Laryngeal Nerve Block for Neurogenic Cough
Prospective randomized placebo-controlled trial assessing the efficacy of superior laryngeal nerve block for adults with neurogenic cough refractory to proton pump inhibitor as determined by improvement in validated cough…
- Trial name
- NCT04468542
- Testing
- Superior laryngeal nerve block - Intervention (Bupivacaine and triamcinolone acetonide suspension)
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- University of South Florida
Airway Obstruction, Vocal Cord Paralysis
Total Versus Partial Arytenoidectomy in Bilateral Vocal Fold Paralysis
Total arytenoidectomy is claimed to increase risk of aspiration and cause more voice loss than other operations performed for bilateral vocal fold paralysis (BVFP). However, objective evidence for such conclusion is lacking.
- Trial name
- NCT01824849
- Testing
- Total arytenoidectomy, Partial arytenoidectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Hacettepe University
Asthma, Wheezing
Swiss Paediatric Airway Cohort
The Swiss Paediatric Airway Cohort (SPAC) is a national, prospective clinical cohort of children and adolescents who visit physicians in Switzerland for recurrent wheeze, cough, and exercise- or sleep-related respiratory…
- Conditions
- Asthma, Wheezing, Cough, Exercise Induced Bronchospasm
- Trial name
- SPAC (NCT03505216)
- Where
- 12 sites in Austria, Switzerland
- Volunteers
- 6,000 people
- Sponsor
- University of Bern
Laryngeal Edema
Cuff Leak Test and Airway Obstruction in Mechanically Ventilated ICU
Introduction: Endotracheal intubation and mechanical ventilation are lifesaving interventions that are commonly done in the intensive care unit (ICU).
- Trial name
- COMIC (NCT03372707)
- Testing
- Cuff Leak Test
- Where
- 3 sites in Canada, Poland and 1 more
- Volunteers
- 100 people
- Sponsor
- McMaster University
Breathing, Mouth, Lung Function Decreased
Evaluating the Use of a Device Called Impulse Oscillometry in Participants With Vocal Cord Disorders or Asthma
This study will determine if airway resistance to airflow and pressure, measured by Impulse Oscillometry, is impacted in subjects with vocal cord disorders and whether these measurements are different when compared to subjects…
- Conditions
- Breathing, Mouth, Lung Function Decreased, Vocal Cord Dysfunction, Laryngeal Obstruction
- Trial name
- NCT05246930
- Testing
- Impulse Oscillometer
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- University of Rochester
Airway Complication of Anesthesia
Ultrasound Guided Superior Laryngeal Nerve Block Compared With Blind Block Technique
The aim of this study is to evaluate the effect of ultrasound guided technique for block of internal branch of superior laryngeal nerve in surgical patient in comparison to blind anatomical technique.
- Trial name
- NCT04623645
- Testing
- ultrasound technique
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Superior Laryngeal Nerve Block
Thyroid Cartilage Plane VS Superior Laryngeal Nerve Space Block in Awake Tracheal Intubation
The aim of this clinical trial is to compare the effectiveness and safety of ultrasound-guided thyroid cartilage plane approach with the superior laryngeal nerve space approach for superior laryngeal nerve block in awake tracheal…
- Trial name
- NCT07397234
- Testing
- Ultrasound-guided bilateral Thyroid Cartilage Plane Block, Ultrasound-guided bilateral Superior Laryngeal Nerve Space Block
- Where
- 2 sites in China
- Volunteers
- 94 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Respiratory Failure
Cuff Leak Test and Airway Obstruction in Mechanically Ventilated ICU Patients
The COSMIC trial will be a multicentred, national, parallel-group, pragmatic vanguard pilot trial.
- Trial name
- COSMIC (NCT05456542)
- Testing
- Cuff Leak Test, Dexamethasone 4mg
- Where
- 5 sites in United States, Canada and 1 more
- Volunteers
- 100 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Cleft Palate, Cleft Lip
Perioperative Respiratory Adverse Events in Cleft Lip and Palate Surgery: Incidence, Risk Factors, and Clinical Scoring
Cleft lip and palate surgeries present unique anesthetic challenges due to shared airway access with the surgical field, frequent anatomical abnormalities, and a predominantly infant and toddler population.
- Conditions
- Cleft Palate, Cleft Lip, Laryngospasm, Bronchospasm
- Trial name
- NCT07651904
- Testing
- Standard General Anesthesia per Institutional Protocol
- Volunteers
- 150 people
- Sponsor
- Marmara University Pendik Training and Research Hospital
Cough
Office-Based Superior Laryngeal Nerve Block for Treatment of Neurogenic Cough
The purpose of this study is to evaluate if office-based injection of a local anesthetic/steroid combination at the area of one superior laryngeal nerve can decrease cough frequency and alleviate symptoms of chronic cough in…
- Trial name
- NCT04642352
- Testing
- superior laryngeal nerve block
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Alabama at Birmingham
Endoscopic Laryngeal Surgery
Dex vs SLNB in Spontaneous Breathing Via THRIVE for Laryngeal Surgery
This prospective, randomized controlled trial evaluated the efficacy and safety of two anesthetic strategies-dexmedetomidine infusion and ultrasound-guided superior laryngeal nerve block (SLNB)-in patients undergoing…
- Trial name
- NCT05581485
- Testing
- Dexmetedomedine infusion, Ultrasound-Guided Superior Laryngeal Nerve Block (SLNB)
- Where
- Taiwan
- Volunteers
- 46 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Exercise Induced Asthma, Exercise Induced Pharyngeal Collapse
Diagnostics and Quality of Life With EIA and EILO
The purpose of this study is to investigate the quality of life of subjects suffering from dyspnoea while exercising and quantify the number of diagnoses of Exercise induced Asthma (EIA) and Exercise induced laryngeal obstruction…
- Trial name
- NCT03550456
- Testing
- ECC, ECC with CLE, Speech therapy
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Johann Wolfgang Goethe University Hospital