Clinical trials: Laser
Actinic Keratosis
Efficacy of Ablative Fractional Laser-assisted Photodynamic Therapy According to the Laser Density for Actinic Keratosis
Erbium:yttrium aluminum garnet (Er:YAG) ablative fractional laser-assisted photodynamic therapy (AFL-PDT) has shown significant benefit for the treatment of actinic keratosis(AK).
- Trial name
- NCT03731988
- Testing
- lidocaine/prilocaine (5%) application, 2940-nm Er:YAG AFL pretreatment, MAL application
- Where
- South Korea
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Dong-A University
Pulp and Periapical Tissue Disease, Pulp Necroses
The Efficacy of Laser in Root Canal Disinfection
The aim of this study is to assess in vivo the efficacy of Er,Cr:YSGG/diode laser and Diode/EDTA on bacterial count in root canal treatment in an evidence-based clinical trial.
- Conditions
- Pulp and Periapical Tissue Disease, Pulp Necroses, Pulp; Granuloma
- Trial name
- NCT05964686
- Testing
- Conventional group (NaOCl/EDTA), Dual laser group (Er,Cr:YSGG/Diode):, Combined group (EDTA/Diode):
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Malaria Transmission, Malaria Prevention
Long-acting Spatial Emanators / Repellents (LASER)
Malaria is a major problem in western Kenya, particularly around Lake Victoria. Whilst current prevention methods like bed nets and vaccines help to reduce malaria burden, additional tools are needed to better protect communities…
- Conditions
- Malaria Transmission, Malaria Prevention, Malaria
- Trial name
- LASER (NCT07387341)
- Testing
- Guardian, IRS with Pirimiphos - methyl
- Where
- Kenya
- Volunteers
- 22,815 people, healthy volunteers welcome
- Sponsor
- Liverpool School of Tropical Medicine
Cataract
Corneal Incisions With the IntraLase iFS Femtosecond Laser System
The IntraLase iFS femtosecond laser system can create corneal arcuate incisions for cataract surgery.
- Trial name
- NCT01713660
- Testing
- iFS Femtosecond Laser
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Healthy
Comparison of the Effects of Injectable Platelet-rich Fibrin and Low-dose Laser Applications on Palatal Wound Healing.
The investigators will evaluate the findings related to pain and bleeding, quality of life after surgery, and wound healing in participants who received injectable platelet-rich fibrin (i-PRF) and low-dose laser therapy to the…
- Trial name
- NCT06744270
- Testing
- i-PRF group, low-dose laser group
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Esra Bozkurt
Fissure Sealant
Clinical Efficacy of Different Fissure Sealant Materials in the Newly Erupted Non-Carious First Permanent Molars
The aim of this study is to compare the clinical retention rates, marginal adaptation, marginal discoloration and secondary caries formation of two different types of resin-modified glass ionomers (Fuji® II LC; Clinpro™ XT…
- Trial name
- NCT04854720
- Testing
- Fuji® II LC CAPSULE, Clinpro™ XT Varnish, Beautifil Flow
- Where
- Turkey (Türkiye)
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Cutaneous Lupus Erythematosus
Treatment of Cutaneous Lupus Erythematosus (CLE) With the 595 nm Flashlamp Pulsed Dye Laser
The purpose of using the 595 nm Vbeam Perfecta™ flashlamp-excited, pulsed dye laser in this study is to help improve study patients' skin disease.
- Trial name
- NCT00523588
- Testing
- laser treatment (Candela Vbeam Perfecta™)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
POH
Evaluation of the Effectiveness of the PiQo4 System for Reduction of Infra-orbital Pigmentation
A total of 10 healthy subjects at a single site, aged 18-65 years old and Fitzpatrick skin type I-IV with mild to moderate infra-orbital hyperpigmentation on the background of epidermal and/or dermal pigmentation that wish to…
- Trial name
- NCT04214873
- Testing
- PiQo4 Laser System
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Focus Medical, LLC
Caries, Diagnoses Disease
Evaluation of Caries Detection Methods
The investigators aim will be to compare the diagnostic performance of clinical visual examination (ICDAS II), intraoral/bite wing radiography (BW), near infrared light transillumination (NIR-LT), and laser fluorescence (LF), in…
- Trial name
- NCT05064566
- Testing
- caries assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Nazan Kocak Topbas
Astigmatism
Prospective Evaluation of the Long-term Effectiveness of the Femtosecond Laser-assisted Arcuate Incisions
This clinical study is an open, controlled, prospective, single center, single-surgeon, post-market-clinical-follow-up study to evaluate the long-term (18 months) effectiveness of the femtolaser-assisted astigmatic keratotomy.
- Trial name
- NCT02164994
- Where
- Czechia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Technolas Perfect Vision GmbH
Photoaging, Wrinkle
Evaluating Procedure Pairing of a Post-Procedure Cream Versus a Comparator in Patients Treated With Fractional Ablative CO2 Laser for Facial Rejuvenation
This randomized, single-center, double-blinded, split-face, controlled clinical trial was conducted to investigate the tolerability, safety, and efficacy of a post-procedure cream when used immediately after fractional ablative…
- Conditions
- Photoaging, Wrinkle, Skin Laxity
- Trial name
- NCT06366503
- Testing
- Fractional Ablative CO2 Laser, Facial Cleanser, Facial Moisturizer
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Revision Skincare
Wrinkle
Soluble Hyaluronic Acid Microneedle VS. Non-ablative Fractional Laser on Infraorbital Wrinkles.
This study is a prospective half-face controlled study, aiming to evaluate the therapeutic effects and adverse reactions of soluble hyaluronic acid microneedle and non-ablative fractional laser on infraorbital wrinkles and…
- Trial name
- NCT04989361
- Testing
- Soluble Hyaluronic Acid Microneedle, Non-fractional laser
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Shanghai Dermatology Hospital
Dental Anxiety
Evaluation of Dental Anxiety in Second-Stage Implant Surgery With Er,Cr:YSGG Laser
Implants embedded under the oral mucosa were exposed with scalpel (Group 1) or laser surgery (Group 2). Before the operation the patients were asked to fill the State-Trait Anxiety Inventory (STAI) and Dental Anxiety Scale (DAS)…
- Trial name
- NCT03871101
- Testing
- Scalpel, 2780 nm Er,Cr:YSGG Laser
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
IBS, Food Intolerance
Confocal Laser Endomicroscopy in IBS Patients
This study will assess dynamic effects of two major antigens on the duodenal mucosa by confocal laser endomicroscopy (CLE). Patients will be blinded to the antigens used (wheat, yeast).
- Trial name
- NCT02313207
- Testing
- FODMAP
- Where
- Germany
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospital Schleswig-Holstein
Stress Urinary Incontinence
Laser and High Intensity Tesla Magnetic Stimulation (HITS) for Stress Urinary Incontinence (SUI)
To investigate the efficacy of combined laser and HITS treatment for female stress urinary incontinence (SUI)
- Trial name
- NCT05670392
- Testing
- laser and High intensity Tesla magnetic stimulation, laser (without HITS treatment)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cork University Maternity Hospital
Tattoo; Pigmentation
Clinical Study to Evaluate the Performance of the PicoWayTM 1064 nm/ 785 nm/ 532nm Picosecond Laser for Tattoo Removal
This is an open-label, multi-center study. Subjects in this study will receive up to eight (8) treatments in 11±5 weeks (6-16 weeks) interval, with the PicoWayTM device using the 1064 nm/ 785±20 nm/ 532 nm handpiece according to…
- Trial name
- NCT02700932
- Testing
- PicoWay
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Syneron Medical
Astigmatism
Safety and Effectiveness of Wavefront-guided LASIK for the Correction of Mixed Astigmatism
To demonstrate that wavefront-guided LASIK with measurements from iDesign is safe and effective in the treatment of mixed astigmatism.
- Trial name
- NCT01675492
- Testing
- LASIK
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Healthy
Evaluation of the UltraClear Laser Workstation for Skin Treatment - Histology Study of Laser Ablation on Human Skin
Evaluation of the UltraClear Laser Workstation for Skin Treatment - Histology Study of Laser Ablation on human skin
- Trial name
- NCT05202834
- Testing
- UltraClear
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- FA Corporation
Skin Aging, Skin Rejuvenation
Comparative Study of a 1064-nm Fractional Picosecond Laser Versus IPL in Facial Rejuvenation
This is a single-center, prospective, randomized controlled trial conducted at Huashan Hospital, Fudan University. The purpose of this study is to compare the effectiveness and safety of two non-invasive treatment options-1064-nm…
- Conditions
- Skin Aging, Skin Rejuvenation, Photoaging
- Trial name
- NCT07122310
- Testing
- 1064-nm Fractional Picosecond Laser (PicoWay), Intense Pulsed Light Therapy (M22 IPL System)
- Where
- China
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Huashan Hospital
Generalized Chronic Periodontitis
Erbium Chromium: YSGG Laser Effect on Surgical Treatment of Chronic Periodontitis
Microbiological and Clinical assessment of Er,Cr:YSGG laser in conjunction to open flap debridement (OFD) in treatment of chronic periodontitis through real time PCR assay for quantification of total bacterial load.
- Trial name
- NCT03810560
- Testing
- laser device Er,Cr:YSGG laser
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- alaa
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