Clinical trials: Laser Endomicroscopy
Barrett Syndrome, Barrett's Syndrome
CLE for Assessment of Neoplasia After Mucosal Ablation or Resection of Gastrointestinal Neoplasia
This study focuses on demonstrating the value of probe-based Confocal Laser Endomicroscopy (pCLE) in guiding endoscopic therapeutic procedures in Barrett's Esophagus (BE).
- Conditions
- Barrett Syndrome, Barrett's Syndrome, Barrett's Esophagus, Barrett Esophagus
- Trial name
- CLEAN-MARGIN (NCT01032044)
- Testing
- Standard endoscopic evaluation, pCLE guided evaluation
- Where
- 6 sites in United States, France and 1 more
- Volunteers
- 164 people
- Sponsor
- Mauna Kea Technologies
Frozen Sections, Indocyanine Green
Multi-center Study on CCeLL-In Vivo's Clinical Efficacy for Intraoperative Brain Tumor Diagnosis.
The primary objective of this study is to demonstrate the non-inferiority of cCeLL compared to frozen section analysis. The investigational device is intended for use with indocyanine green (ICG) for fluorescence imaging as an…
- Conditions
- Frozen Sections, Indocyanine Green, Brain Tumor
- Trial name
- PRECISION (NCT06867978)
- Testing
- cCeLL In vivo, Indocyanine Green
- Volunteers
- 100 people
- Sponsor
- VPIX Medical
Cervix Cancer, Endometrium Cancer
Probe-based and Needle-based Confocal Laser Endomicroscopy During Gynaecological Procedures.
The protocol aims at demonstrating the technical feasibility and safety of doing endomicroscopic imaging (both probe-based confocal laser endomicroscopy (pCLE) and needle-based confocal laser endomicroscopy, nCLE) during…
- Conditions
- Cervix Cancer, Endometrium Cancer, Ovarian Cancer, Carcinoma in Situ of Fallopian Tube
- Trial name
- NCT02221076
- Testing
- Confocal Laser Endomicroscopy (CLE)
- Where
- France
- Volunteers
- 16 people
- Sponsor
- Mauna Kea Technologies
Frozen Sections, Indocyanine Green (ICG)
A PROSPECTIVE, SINGLE-CENTERED, ASSESSOR-BLINDED STUDY TO EVALUATE THE CLINICAL EFFICACY OF THE PROPOSED CELL/TISSUE HISTOPATHOLOGY PROCESSOR CCELL (CONFOCAL FLUORESCENCE ENDOMICROSCOPY) FOR INTRAOPERATIVE DIAGNOSIS IN BRAIN TUMORS
The primary objective of this single-center study is to demonstrate the performance of cCeLL, used in real time, compared to frozen section analysis.
- Conditions
- Frozen Sections, Indocyanine Green (ICG), Brain Tumor
- Trial name
- NCT07254845
- Testing
- cCeLL In vivo, Indocyanine Green
- Volunteers
- 30 people
- Sponsor
- VPIX Medical
Lung Neoplasms
Confocal Laser Endomicroscopy Nodule Localization by Robotic Bronchoscopy
This study is designed to evaluate the safety and feasibility of real-time needle-based confocal laser endomicroscopy (nCLE) in improving diagnostic accuracy of robotic-assisted bronchoscopy (RANB) biopsy performed with the…
- Trial name
- CLEAR (NCT05231278)
- Testing
- nCLE aided RANB biospy
- Where
- 4 sites in United States
- Volunteers
- 53 people
- Sponsor
- Johnson & Johnson Enterprise Innovation Inc.
Pancreatic Cyst, Pancreatic Neoplasms
Clinical Evaluation Of Needle-based Confocal Laser Endomicroscopy in The Lymph Nodes Along With Masses and Cystic Tumors of the Pancreas
This study focuses on three different lesions: pancreatic cysts, lymph nodes near the gastrointestinal tract and pancreatic masses.
- Conditions
- Pancreatic Cyst, Pancreatic Neoplasms, Pancreatic Adenoma, Pancreatic Cancer
- Trial name
- CONTACT (NCT01563133)
- Testing
- EUS-FNA, nCLE
- Where
- 3 sites in France
- Volunteers
- 330 people
- Sponsor
- Mauna Kea Technologies
Liver Percutaneous Biopsy or Ablation, Kidney Percutaneous Biopsy or Ablation
Needle-based Confocal Laser Endomicroscopy in CT-guided Percutaneous Procedures
This study is a prospective study in order to demonstrate the technical feasibility and safety of doing endomicroscopic imaging during interventional radiology procedure in two main indications: Kidneys and liver.
- Trial name
- NCT02288104
- Testing
- needle based confocal endomicroscopy
- Where
- France
- Volunteers
- 16 people
- Sponsor
- Mauna Kea Technologies
Undergoing Esophagogastroduodenoscopy (EGD)
High Resolution Optical Imaging of the Esophagus Using the Nvision Volumetric Laser Endomicroscopy (VLE™) Imaging System
This is a single center, single arm, open label observational trial of patients undergoing EGD. The primary objective of this clinical trial is to evaluate the ability of physicians to position the NvisionVLE catheter to acquire…
- Trial name
- NCT01844921
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- NinePoint Medical
Lung Percutaneous Biopsy, Liver Percutaneous Biopsy
Needle-based Confocal Laser Endomicroscopy in Fluoroscopy-guided Procedures
This study is a prospective study in order to demonstrate the technical feasibility and safety of doing endomicroscopic imaging during interventional radiology procedure in two main indications: lung and liver.
- Trial name
- NCT02224885
- Testing
- CT-guided percutaneous biopsy or ablation
- Where
- France
- Volunteers
- 6 people
- Sponsor
- Mauna Kea Technologies
Barrett'S-associated Dysplasia, Intramucosal Adenocarcinoma
A Comparison of Volumetric Laser Endomicroscopy (VLE) and Endoscopic Mucosal Resection (EMR) in Patients With Barrett's Dysplasia or Intramucosal Adenocarcinoma
Barrett's esophagus (BE) is a pre-neoplastic condition formed by the metaplasia of the normal squamous mucosa of the distal esophagus into a specialized intestinal mucosa.
- Trial name
- NCT01862666
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- NinePoint Medical
Barrett's Esophagus
High Resolution Optical Imaging of Barrett's Esophagus Using Nvision Volumetric Laser Endomicroscopy (VLE)
The primary objective of this clinical trial is to evaluate the performance of the Nvision Volumetric Laser Endomicroscopy (VLE) system to visualize subsurface tissue in subjects undergoing esophagogastroduodenoscopy (EGD) and to…
- Trial name
- NCT01503411
- Where
- 3 sites in United States
- Volunteers
- 120 people
- Sponsor
- NinePoint Medical