Clinical trials: Laser Photocoagulation
Soft Tissue Healing
The Effect of Laser Photocoagulation on the Soft Tissue Healing During Socket Preservation
The main aim of this study was to evaluate clinically the effect of laser photocoagulation in comparison to the non-resorbable dense polytetrafluroethylene (dPTFE) membrane on the soft tissue healing during socket preservation…
- Trial name
- NCT04353999
- Testing
- Socket sealing by diode laser photocoagulation, socket sealing with dense polytetrafluroethylene membrane
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Hams Hamed Abdelrahman
Diabetic Macular Edema
A Pilot Study of Peribulbar Triamcinolone Acetonide for Diabetic Macular Edema
The study involves the enrollment of patients over 18 years of age with diabetic macular edema involving the center of the macula who have not already been given maximal laser treatment.
- Trial name
- Peribulbar (NCT00369486)
- Testing
- Focal laser photocoagulation, 40mg triamcinolone, 20mg triamcinolone
- Volunteers
- 113 people
- Sponsor
- Jaeb Center for Health Research
Diabetic Retinopathy, Diabetic Macular Edema
Laser-Ranibizumab-Triamcinolone for Diabetic Macular Edema
The purpose of the study is to find out which is a better treatment for diabetic macular edema (DME): laser alone, laser combined with an intravitreal injection of triamcinolone, laser combined with an intravitreal injection of…
- Trial name
- LRT for DME (NCT00444600)
- Testing
- Triamcinolone Acetonide + laser, Ranibizumab + laser, Ranibizumab + deferred laser
- Where
- 50 sites in United States
- Volunteers
- 691 people
- Sponsor
- Jaeb Center for Health Research
Proliferative Diabetic Retinopathy, Diabetic Retinopathy
Single Session vs Multiple-Session Panretinal Photocoagulation for Treatment of Proliferative Diabetic Retinopathy
Proliferative diabetic retinopathy (PDR) is the leading cause for blindness in working-age adults. The current gold standard treatment for PDR is panretinal photocoagulation (PRP).
- Conditions
- Proliferative Diabetic Retinopathy, Diabetic Retinopathy, Diabetic Retinopathy Visually Threatening, Diabetic Macular Edema
- Trial name
- SMART-PRP (NCT06549023)
- Testing
- Single-session panretinal PRP (SS-PRP), Multiple-session panretinal PRP (MS-PRP)
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Vastra Gotaland Region
Retina Disease, Retinopathy of Prematurity
Intravitreal Ranibizumab Injection for Aggressive Versus Type 1 Prethreshold Retinopathy of Prematurity
Despite advances in the neonatal intensive care units, retinopathy of prematurity (ROP) has become a common reason for blindness and visual disabilities in premature infants so that it accounts for about 5% and 30% of such…
- Conditions
- Retina Disease, Retinopathy of Prematurity, Ranibizumab
- Trial name
- NCT05701124
- Testing
- Ranibizumab (0.25 mg/0.025 mL)
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Zagazig University
Diabetic Macular Edema
Evaluation of the Effects of Selective Photocoagulation for the Treatment of Diabetic Macular Edema
The population of people suffering from diabetes is rapidly increasing, from an estimated 110 million in 1994 to 221 million in 2010.
- Trial name
- SRT (NCT01355692)
- Testing
- Nd: YLF laser treatment
- Where
- 2 sites in Israel
- Volunteers
- 32 people
- Sponsor
- Lumenis Be Ltd.
Diabetic Macular Edema
Micropulse 577 nm Laser Photocoagulation Versus Conventional 532 nm Laser Photocoagulation for Diabetic Macular Oedema
The purpose of this study is to determine whether the new micropulse 577 nm yellow laser is a better treatment option compared to the conventional 532 nm green laser for diabetic macular edema.
- Trial name
- UMDMO (NCT01045239)
- Testing
- Micropulse 577 nm yellow diode laser, 532 nm green diode laser
- Where
- Malaysia
- Volunteers
- 100 people
- Sponsor
- University of Malaya
Acute Retinal Necrosis, Retinal Detachment
Prophylactic Laser Photocoagulation and Vitrectomy for Acute Retinal Necrosis
Acute retinal necrosis (ARN) is a rare infectious retinitis which can potentially lead to devastating visual outcomes. ARN is diagnosed on the basis of the clinical appearance and disease course according to the diagnostic…
- Conditions
- Acute Retinal Necrosis, Retinal Detachment, Laser Photocoagulation, Vitrectomy
- Trial name
- NCT02222857
- Where
- Taiwan
- Volunteers
- 23 people
- Sponsor
- National Taiwan University Hospital
Visual Impairment Due to Diabetic Macular Edema
Safety and Efficacy of Ranibizumab in Diabetic Macular Edema
This study was designed to confirm the efficacy and safety of laser photocoagulation as adjunctive therapy to ranibizumab 0.5 mg versus laser monotherapy in patients with visual impairment due to Diabetic Macular Edema.
- Trial name
- RELATION (NCT01131585)
- Testing
- Active laser photocoagulation, Ranibizumab 0.5 mg
- Where
- 34 sites in Germany
- Volunteers
- 128 people
- Sponsor
- Novartis Pharmaceuticals
Proliferative Diabetic Retinopathy
Analgesic Effect of Etoricoxib (ARCOXIA®) 120MG During Retinal Laser Photocoagulation
The study wants to show if the medication etoricoxib 120 mg have reduces the patients pain during the laser photocoagulation, for diabetic retinopathy.
- Trial name
- NCT00529594
- Testing
- Etoricoxib (Treatment Group)
- Where
- Brazil
- Volunteers
- 44 people
- Sponsor
- University of Sao Paulo
Proliferative Diabetic Retinopathy - High Risk
Patient Comfort Using Green vs. Yellow Pan Retinal Photocoagulation
Our aim is to compare patient comfort when using the 532 nanometer (green) wavelength laser to the 577 nanometer (yellow) wavelength laser during pan retinal photocoagulation to treat patients with diabetic retinopathy.
- Trial name
- NCT02995629
- Testing
- laser indirect ophthalmoscopy pan retinal photocoagulation
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Wills Eye
Twin to Twin Transfusion
The Effect of Uterine Entry In Fetoscopic Laser Photocoagulation for Twin-To-Twin Transfusion Syndrome
The purpose of this study is to evaluate whether the entry technique surgeons use to get inside the uterus to perform fetoscopic laser photocoagulation for twin-to-twin transfusion syndrome has an effect on the rates of…
- Trial name
- NCT06829901
- Testing
- Fetoscopic Laser Photocoagulation
- Where
- United States
- Volunteers
- 216 people
- Sponsor
- Baylor College of Medicine
Diabetic Retinopathy, Diabetic Retinal Disease
Nursing Intervention Based on Stress Adaptation Theory for Patients Undergoing Diabetic Retinal Laser Surgery
This randomized controlled study evaluated whether a nursing intervention based on stress adaptation theory could improve pain trajectory and procedural tolerance in patients undergoing ambulatory retinal laser photocoagulation…
- Trial name
- NCT07544381
- Testing
- Nursing Intervention Based on Stress Adaptation Theory, Routine Peri-Procedural Care
- Where
- China
- Volunteers
- 136 people
- Sponsor
- Joint Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong
Retinal Artery Macroaneurysm
Focal Laser Single Intravitreal Ranibizumab Retinal Artery Macroaneurysm.
Treatment options for Retinal artery Macroaneurysm (RAM) include focal laser photocoagulation, intravitreal anti-Vascular Endothelial Growth Factor (anti-VEGF) injection, combined anti VEGF - laser therapy, YAG hyaloidotomy and…
- Trial name
- RAM (NCT05716932)
- Testing
- Dual focal laser and intravitreal Ranibizumab injection
- Where
- Egypt
- Volunteers
- 14 people
- Sponsor
- Dar El Oyoun Hospital
Diabetic Retinopathy
Effect of Laser Treatment for Diabetic Retinopathy on the Optic Disc Topography
This study analyzed diabetic patients without evidence of glaucoma who underwent panretinal photocoagulation to determine the effect on optic disc topographic parameters in non-glaucomatous patients with proliferative diabetic…
- Trial name
- NCT03476967
- Testing
- Panretinal photocoagulation
- Volunteers
- 30 people
- Sponsor
- University of Sao Paulo General Hospital
Pain, Perioperative
Reducing Pain From Retinal Laser With Vibrational Stimulation
The goal of this clinical trial is to learn if Vibration Anesthesia Device works to reduce pain during retinal laser for diabetic retinopathy.
- Trial name
- NCT06649604
- Testing
- Vibration Anesthesia Device, Panretinal Photocoagulation
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of Alberta
Proliferative Diabetic Retinopathy, PDR
The Individually-Marked Panretinal Laser phoTocoagulation for Proliferative Diabetic Retinopathy Study (TREAT)
Background Diabetic eye disease is the most frequent complication among the 320,000 Danes with diabetes. The formation of new vessels (PDR) in the inner part of the eye (retina) is a feared complication and a leading cause of…
- Conditions
- Proliferative Diabetic Retinopathy, PDR, Diabetes
- Trial name
- NCT03113006
- Testing
- Panretinal Photocoagulation
- Where
- Denmark
- Volunteers
- 53 people
- Sponsor
- Odense University Hospital
Non Proliferative Diabetic Retinopathy, Proliferative Diabetic Retinopathy
Changes in Electroretinogram and Contrast Sensitivity After PASCAL Treatment
Laser photocoagulation has become the treatment of choice in PDR. Laser photocoagulation has become the treatment of choice in PDR.
- Trial name
- NCT00563043
- Testing
- PASCAL laser treatment
- Where
- Mexico
- Volunteers
- 8 people
- Sponsor
- Asociación para Evitar la Ceguera en México
Proliferative Diabetic Retinopathy
Bevacizumab as Adjunctive Treatment to Laser Panretinal Photocoagulation for Proliferative Diabetic Retinopathy
This is a prospective, randomized and comparative study is to quantify the functional and structural alterations of the macula in patients with proliferative Diabetic Retinopathy submitted to laser photocoagulation and to…
- Trial name
- NCT01389505
- Testing
- Panretinal photocoagulation, Procedure: Panretinal Photocoagulation (PRP) Drug: Intravitreous injection of Bevacizumab
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Instituto do Coracao
Diabetic Retinopathy, Lasers
Pattern Scanning Laser Pan-retinal Photocoagulation in Proliferative Diabetic Retinopathy
A randomized study to assess the safety and efficacy of single-session pan-retinal photocoagulation (PRP) using Pattern Scan Laser (PASCAL) in proliferative diabetic retinopathy (PDR) - 1,700 shots vs 2,500 shots
- Conditions
- Diabetic Retinopathy, Lasers, Treatment Outcome
- Trial name
- NCT02816073
- Testing
- Pan-retinal photocoagulation using pattern scanning laser
- Volunteers
- 17 people
- Sponsor
- United Christian Hospital