Clinical trials: Laser Photocoagulation
Macular Degeneration
Laser and Medical Treatment of Diabetic Macular Edema
This study will compare the side effects of two laser treatments for diabetic macular edema, a common condition in patients with diabetes.
- Trial name
- NCT00050479
- Testing
- Celecoxib (Celebrex)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- National Eye Institute (NEI)
Diabetic Retinopathy
PASCAL Laser Platform Produces Less Pain Responses Compared To Conventional Laser System
The aim of this study is to compare the severity of expressed pain scores in patients with PDR who underwent either PASCAL or conventional laser and to assess the association between patient characteristics and severity of pain.
- Trial name
- NCT02645383
- Testing
- PASCAL laser, Conventional laser
- Volunteers
- 30 people
- Sponsor
- Kocatepe University
Diabetic Retinopathy, Macular Edema
Intravitreal Bevacizumab (Avastin®) Versus Intravitreal Dexamethasone (Ozurdex™) for Persistent Diabetic Macular Oedema
The specific aims of the study are to test the following hypotheses: That there is a difference in change in visual acuity resulting from treatment with intravitreal bevacizumab compared with dexamethasone implant in eyes with…
- Trial name
- NCT01298076
- Testing
- bevacizumab, dexamethasone
- Where
- 4 sites in Australia
- Volunteers
- 61 people
- Sponsor
- University of Sydney
Central Retinal Vein Occlusion With Macular Edema
Combination of Ranibizumab and Targeted Laser Photocoagulation
Intravitreal injections of Ranibizumab will be applied in all patients according to treatment guidelines. The experimental group will receive additional targeted laser photocoagulation of the peripheral areas of capillary…
- Trial name
- CoRaLaII (NCT04444492)
- Testing
- Ranibizumab Injection, Laser photocoagulation
- Where
- 12 sites in Austria, Germany
- Volunteers
- 88 people
- Sponsor
- University of Giessen
Diabetic Macular Oedema
Sub-threshold Photocoagulation of Diabetic Macular Oedema
Topcon's Endpoint Management (EM) is a new software from the Pascal® laser which allows us to decrease the intensity of the burns (invisible burns) showing some landmarks with normal intensity so the investigators can see the…
- Trial name
- MEM (NCT02309476)
- Testing
- PASCAL Laser, Green Laser 0.75, PASCAL Laser, Green Laser 1, PASCAL Laser, 70% Yellow Laser 0.75
- Where
- United Kingdom
- Sponsor
- Manchester University NHS Foundation Trust
Diabetic Retinopathy
Triamcinolone as Adjunctive Treatment to Laser Panretinal Photocoagulation for Proliferative Diabetic Retinopathy
The purpose of the study is to evaluate intravitreal injection of triamcinolone acetonide after laser panretinal photocoagulation in the treatment of proliferative diabetic retinopathy.
- Trial name
- NCT00443521
- Testing
- Triamcinolone Acetonide 4 mg intravitreal injection, Panretinal photocoagulation
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- University of Sao Paulo
Familial Exudative Vitreoretinopathies
Bromfenac Sodium Hydrate Eye Drops in Familial Exudative Vitreoretinopathy
This study aims to investigate the efficacy and safety of bromfenac sodium hydrate eye drops in patients with familial exudative vitreoretinopathy receiving diode laser photocoagulation.
- Trial name
- NCT05107921
- Testing
- Bromfenac Sodium
- Where
- South Korea
- Volunteers
- 39 people
- Sponsor
- Seoul National University Hospital
Panretinal Photocoagulation
Effect of Argon Laser Panretinal Photocoagulation on Corneal Endothelial Cell Density .
This study investigates the effect of argon laser panretinal photocoagulation (PRP) on the corneal endothelial cell density (ECD) in patients with proliferative diabetic retinopathy (PDR) by comparing ECD measurements before and…
- Trial name
- NCT07157553
- Volunteers
- 45 people
- Sponsor
- Assiut University
Proliferative Diabetic Retinopathy (PDR)
Multicenter 12 Months Clinical Study to Evaluate Efficacy and Safety of Ranibizumab Alone or in Combination With Laser Photocoagulation vs. Laser Photocoagulation Alone in Proliferative Diabetic Retinopathy (PRIDE)
The purpose of this study was to assess the efficacy and safety of the anti-Vascular Endothelial Growth Factor (VEGF) agent ranibizumab (0.5 mg) with or without Panretinal laser photocoagulation (PRP) compared to PRP alone in…
- Trial name
- PRIDE (NCT01594281)
- Testing
- Ranibizumab 0.5 mg, Panretinal laser photocoagulation
- Where
- 23 sites in Germany
- Volunteers
- 107 people
- Sponsor
- Novartis Pharmaceuticals
Macular Edema, Diabetes Mellitus
Laser and Antioxidant Treatment of Diabetic Macular Edema
This study will compare the side effects of two laser treatments for diabetic macular edema, a common condition in patients with diabetes.
- Trial name
- NCT00055042
- Testing
- Vitamin E
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- National Eye Institute (NEI)
Diabetic Retinopathy
Panretinal Photocoagulation for Diabetic Retinopathy With PASCAL Laser
This study will investigate the clinical efficacy and safety of the PASCAL laser (PAttern SCAn Laser) for diabetic retinopathy. Patients with proliferative or severe nonproliferative retinopathy will be treated with panretinal…
- Trial name
- NCT01304225
- Testing
- Panretinal photocoagulation
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Federal University of São Paulo