Clinical trials: Lasers
Wrinkles, Acne Scars
Epidermal Delivery of Ani-Aging Ingredients
To assess the safety and efficacy of an ablative fractional, 2940-nm laser combined with the US Impact and cosmetic -formulations for improving the appearance of wrinkles, acne scars and pigmented skin.
- Conditions
- Wrinkles, Acne Scars, Pigmentation
- Trial name
- NCT01847066
- Testing
- Erbium 2940 plus cosmetics plus Impact, Erbium 2940 plus cosmetics
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Alma Lasers Inc.
Skin Resurfacing
A Phase 4 Clinical Study to Investigate the Effectiveness and Safety of Skin Resurfacing
This study is a prospective, post-marketing (Phase 4) non-registrational single-arm, open-label, multicenter study.
- Trial name
- NCT07214272
- Testing
- Fraxel® FTX Laser System
- Where
- 5 sites in United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Bausch Health Americas, Inc.
Glaucoma
Benchmarking Management of Glaucoma Using the Diopsys VEP/PERG Protocols.
Establish electrophysiological benchmarks, using the Diopsys Visual Evoked Potential/ Pattern ERG (VEP/PERG) protocols of populations with Glaucoma following: 1) Baseline VEP/ERG prior to treatment; and 2) VEP/PERG after…
- Trial name
- NCT02594280
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Diopsys, Inc.
Wrinkle, Rosacea
Evaluation of Cutera Excel V™ Laser With Green Genesis and Micro-Lens Array (MLA)Attachment
Evaluate the Cutera excel V™ Laser with Green Genesis and a Micro-Lens Array (MLA) Attachment
- Conditions
- Wrinkle, Rosacea, Scarring
- Trial name
- NCT03424304
- Testing
- Excel V™ Laser With Green Genesis
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cutera Inc.
Unwanted Fine Facial Hair
Clinical Evaluation to Assess the Safety and Efficacy of GentleMax Pro™/GentleMax Pro Plus™
This clinical study is intended to evaluate the safety and efficacy of the GentleMax Pro Plus™ laser system for its intended use of hair removal while using short pulse durations to improve the efficacy of achieving permanent…
- Trial name
- NCT04975243
- Testing
- GentleMax Pro Plus 755nm and 1064nm laser system
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Candela Corporation
Varicose Veins
Market Penetration of Laser Therapy in Venous Surgery: Ziekenhuis Oost-Limburg - Ziekenhuis Maas En Kempen Center Experience
The goal of this registry is to evaluate the indication for EndoVenous Laser Ablation (EVLA) therapy. Can this be enhanced? What are the reasons for not using the laser? Therefore, this study aims to define clear indications for…
- Trial name
- NCT03856814
- Testing
- ELVeS® Radial® 2ring slim fiber used for EndoVenous Laser Ablation
- Where
- Belgium
- Volunteers
- 500 people
- Sponsor
- Duomed
Coronary Artery Stenosis
Coronary Laser Atherectomy System for Treatment of Coronary Artery Stenosis (SHINE)
This prospective, multi-center clinical trial evaluates the safety and efficacy of the Coronary Laser Atherectomy System for the pretreatment of coronary artery stenosis.
- Trial name
- SHINE (NCT07697638)
- Testing
- Coronary Laser Atherectomy System, CVX300 Laser System
- Volunteers
- 218 people
- Sponsor
- Shanghai MicroPort Rhythm MedTech Co., Ltd.
Tattoo Removal
Pilot Study of Multi-wavelength Laser for Tattoo Removal
To evaluate the safety and efficacy of an investigational version of the Cutera enLighten laser that offers muliple wavelengths for tattoo removal.
- Trial name
- NCT03290547
- Testing
- Cutera enLighten laser
- Where
- 2 sites in United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cutera Inc.
Skin Tightening of the Mandibular and Sub-mandibular Areas
Mandible and Sub-mandible Using the 1440nm Wavelength Laser and Hand Piece
The purpose of this study is to use the 1440nm Wavelength laser along with the hand piece to provide clinical outcome data for treatment of the mandibular and submandibular areas specifically for skin tightening and laser…
- Trial name
- NCT01813747
- Testing
- 1440 nm wavelength laser with handpiece (Cynosure)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Cynosure, Inc.
Androgenetic Alopecia
Treatment of Androgenetic Alopecia in Males and Females
The purpose of this study is to evaluate the efficacy of Low Level Laser and Light Therapy system configured in a novel product called the TopHat 655 system, for promoting hair growth in males and females diagnosed with…
- Trial name
- LLLT (NCT01437163)
- Testing
- TopHat 655 rejuvenation system, Laser and/or Light Hair Rejuvenation System
- Where
- 4 sites in United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Apira Science, Inc.
Lumbar Herniated Intervertebral Disc
The Efficacy and Safety of the 1,414 nm Nd:YAG Laser System for Alleviating Back Pain in a Lumbar Disc Patient
This study aims to evaluate the efficacy and safety of the 1,414nm Nd:YAG laser system (ACCUPLASTI) added to Percutaneous Epidural Neuroplasty (PEN), a conventional treatment, to alleviate back pain in a lumbar herniated…
- Trial name
- NCT02598232
- Testing
- 1,414nm Nd:YAG Laser System
- Volunteers
- 30 people
- Sponsor
- CynosureLutronic
Infrainguinal Peripheral Artery Disease, Peripheral Arterial Disease
Post-Market Registry of AURYON Atherectomy Device in Subjects Affected With Infrainguinal Peripheral Artery Disease
The PATHFINDER Registry is a prospective, non-randomized, single arm, multicenter observational study. This pilot registry is aimed to evaluate the performance (peri-procedural) and clinical outcomes (intermediate and long-term)…
- Conditions
- Infrainguinal Peripheral Artery Disease, Peripheral Arterial Disease, PAD
- Trial name
- PATHFINDER (NCT04229563)
- Testing
- AURYON Atherectomy System
- Where
- 10 sites in United States
- Volunteers
- 102 people
- Sponsor
- Angiodynamics, Inc.
Photodamage, Irregular Pigmentation
Comparison of the RevLite Electro-optic Q-Switched Neodymium-doped Yttrium Aluminium Garnet (EO QS Nd:YAG) Laser to a Fractionated Laser System
The purpose of this study is to compare the results of treatment between the side of the face treated with the RevLite Laser and the side of the face treated with a fractionated laser system.
- Conditions
- Photodamage, Irregular Pigmentation, Acne Scars
- Trial name
- NCT00955461
- Testing
- RevLite laser treatment, Fractionated Laser treatment
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- ConBio, a Cynosure Company
Wounds and Injuries
Laser Speckle Imaging for Wound Perfusion Monitoring (WoundImager)
The purpose of this study is to investigate the efficacy of an optical device designed and developed to quantitatively monitor blood flow velocity of wound sites.
- Trial name
- NCT01675583
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- CW Optics, Inc.
Cataracts
Laser Cataract Surgery With the Femtosecond Laser Technology
The purpose of this study is to prove the efficacy and safety of the Femtosecond laser to create a clear corneal incision during cataract surgery.
- Trial name
- NCT01382823
- Testing
- Femtosecond Laser
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Innovative Medical
Port Wine Stains
Port Wine Stains Treatment Matrix RF Study
The purpose of this study is to evaluate the efficacy and safety of the Matrix RF for Port Wine Stains based on clinical and histological analyses.
- Trial name
- NCT01101360
- Testing
- Matrix RF, Matrix RF followed by Pulse Dye Laser, Pulse Dye Laser followed by Matrix RF
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Syneron Medical
Circumferential Reduction, Waist Circumferential Reduction
BTL-9000 Low Level Laser Therapy for the Waist Circumferential Reduction
Prospective, two-arm, randomized study of the effectiveness of the BTL-9000 LLLT in achieving 3 cm or greater average waist circumferential reduction in LLLT group of subjects relative to the base line and 1 cm or greater…
- Trial name
- NCT02023385
- Testing
- BTL-9000 LLLT
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- BTL Industries Ltd.
Scarring, Acne
Evaluation of the Cutera Enlighten™ Laser With Micro-Lens Array (MLA) Handpiece Attachment
The purpose of this pivotal investigation is to evaluate the efficacy and safety of the Cutera enlighten multi-wavelength 532 nm and 1064 nm picosecond pulse duration laser and an investigational micro-lens array (MLA) handpiece…
- Trial name
- NCT03430921
- Testing
- Enlighten™ Laser and a MLA Attachment
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Cutera Inc.
Coronary Artery Disease, Coronary Artery Calcification
Modification of Coronary Calcium With Laser Based Intravascular Lithotripsy for Coronary Artery Disease (FRACTURE)
The FRACTURE Trial is a prospective, non-randomized, single-arm, multicenter, interventional study in US and international centers.
- Trial name
- FRACTURE (NCT06181240)
- Testing
- Intravascular lithotripsy
- Where
- 46 sites in United States, Belgium and 5 more
- Volunteers
- 426 people
- Sponsor
- Bolt Medical
Musculoskeletal Pain
The Effect of the Erchonia GVL Low Level Laser Therapy on Neck and Shoulder Pain
This study is to see if applying green and violet low level laser light to the neck and shoulders can help to reduce pain in the neck and shoulders.
- Trial name
- NCT04895618
- Testing
- Erchonia GVL
- Where
- 3 sites in United States
- Volunteers
- 43 people
- Sponsor
- Erchonia Corporation