Clinical trials: Lasers
Scars After Surgical Intervention
10 600 nm Ablative Fractional Laser Treatment of Scars: a Prospective Single Blinded Within Patient Controlled Randomized Trial
Rationale The cosmetic aspect of scars is a frequent reason for consultation. It plays an important role in patient satisfaction and self-image. Several treatment modalities are proposed for scars with variable success.
- Trial name
- NCT01639105
- Testing
- Laser treatment
- Where
- Belgium
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Myopia
IntraLase vs Hansatome Flaps in LASIK
This study compared the clinical outcomes between fellow eyes randomized to either IntraLase femtosecond laser-created flaps or Hansatome mechanical keratome-created flaps during wavefront-guided laser in situ keratomileusis.
- Trial name
- NCT00691431
- Testing
- LASIK
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Stanford University
Colorectal Polyp
Optical Diagnosis Versus Laser Measurement of Polyps' Size During Colonoscopy and Implications for Surveillance
Recent updates of the guidelines on polyp surveillance of the American Society of Gastrointestinal Endoscopy (ASGE) and European Society of Gastrointestinal Endoscopy (ESGE) increasingly focus on size of polyps as an important…
- Trial name
- NCT05489380
- Testing
- AccuMeasure
- Where
- 3 sites in United States, Netherlands
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Laser, Tooth
Efficacy of Er,Cr:YSGG Laser in Partial Pupotomy
The aim of this study was to compare the efficacy of partial pulpotomy treatment using MTA and Er,Cr:YSGG + MTA in permanent immature molar teeth with deep dentin caries.
- Conditions
- Laser, Tooth, Pulpotomy
- Trial name
- NCT04010929
- Testing
- Partial pulpotomy with laser+MTA, Partial pulpotomy with MTA
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Merve Erkmen Almaz
Periodontal Pocket
Quantitation of Bacteria Associated With Severe Periodontitis by Real -Time PCR Following Application of Diode Laser
1. Primary objective To measure the gingival crevicular levels of A.actinomycetemcomitans and P.gingivalis after intra-pocket application of diode laser in severe periodontitis (stage 3 grade C) patients. 2.
- Trial name
- NCT05222737
- Testing
- medency diode laser, spirazole forte
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Foot Diseases, Myofascial Pain
Myofascial Induction Effects on Stabilometry Versus Sham Laser
The objective is to determine the effectiveness of myofascial induction effects on stabilometric variables. Forty healthy subjects will be recruited for a single blind clinical trial.
- Trial name
- NCT04628286
- Testing
- Myofascial Induction
- Where
- Spain
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Mayuben Private Clinic
Pericoronitis
Evaluation of Photodynamic Therapy in Pericoronitis
In order to reduce the chances of systemic dissemination of the infection and the use of antibiotics, it is mandatory to test effective treatments in the initial phase of pericoronitis aiming to avoid the evolution of the…
- Trial name
- pdt (NCT03576105)
- Testing
- irrigation /sterile saline, Conventional methylene blue as photosensitizer, Methylene blue for oral use as photosensitizer
- Where
- Brazil
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Asthma
Development of a Breath Analyzer for Asthma Screening
Annually, asthma is responsible for 1 million emergency room visits, 400,000 hospitalizations, and 5000 deaths according to the NHLBI.
- Trial name
- NCT00386737
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Ekips Technologies
Irritable Bowel Syndrome, Inflammatory Bowel Disease
Assessment of Small Intestinal Bowel Epithelial Gaps in Irritable Bowel Syndrome
The study aims to: 1. Determine whether the density of epithelial gaps in terminal ileum of patients with irritable bowel syndrome (IBS) is different from that in inflammatory bowel disease (IBD) patients and normal controls by…
- Trial name
- NCT01632488
- Where
- China
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Shandong University
Malocclusion, Orthodontic Tooth Movement
Micro-osteoperforation Versus Photobiomodulation Therapy for Accelerating Maxillary Canine Retraction
Orthodontic treatment often requires moving the upper canine teeth (the pointed teeth) into the spaces left after removing premolar teeth.
- Conditions
- Malocclusion, Orthodontic Tooth Movement, Maxillary Canine Retraction
- Trial name
- MOP-PBMT (NCT07658235)
- Testing
- Micro-osteoperforation (MOP), Photobiomodulation Therapy using 976 nm Diode Laser, Conventional orthodontic canine retraction
- Where
- Iraq
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Kufa University
Lepromatous Leprosy
Microcirculatory Impairment in Patients With Leprosy
In this study the investigators have aimed to evaluate morphology and reactivity of cutaneous microcirculation in patients with lepromatous leprosy.
- Trial name
- NCT02085317
- Testing
- acetylcholine Iontophoresis, sodium nitroprusside Iontophoresis
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Curt Treu
Melasma
Combination Topical Cysteamine and Fractional 1927nm Low-Powered Diode Laser for Treatment of Facial Melasma
The primary objective of our study is to determine the efficacy of combined topical cysteamine cream with a 1927 diode non-ablative laser (Clear + Brilliant Permea®; Solta Medical, Inc.), compared to topical cysteamine (Cyspera)…
- Trial name
- NCT05656833
- Testing
- Fractional 1927nm Low-Powered Diode Laser, Topical Cysteamine
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- UnionDerm
Acne Scars - Mixed Atrophic and Hypertrophic
Safety and Efficacy Investigation on the Effects of ClearSkin Non-ablative ER:Glass 1540nm Laser Module in the Treatment of Acne Scars.
The ClearSkin module, Er: Glass 1540nm, is largely used in the treatment of acne vulgaris and acne scars. The non-ablative ER:Glass 1540 nm laser deeply penetrates the skin, causing thermal damage to the sebaceous glands…
- Trial name
- NCT06102343
- Testing
- Alma Harmony
- Where
- Portugal
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Alma Lasers
Peri-Implantitis
Efficacy of Er: YSGG Laser in Treatment of Peri-implantitis
This study will be carried out to evaluate the efficacy of Er: YSGG laser on oral biofilm removal from implant surface in various peri-implant defect morphology in the treatment of peri-implantitis as a primary objective.
- Trial name
- NCT05137821
- Testing
- Er: YSGG laser, no therapy
- Where
- Egypt
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Myopia, Astigmatism
Wavefront-guided PRK vs Wavefront-optimized PRK
The purpose of the study is to compare the results of PRKK surgery when using wavefront-guided excimer laser treatment compared to wavefront optimized excimer laser treatment in patients with nearsightedness with and without…
- Trial name
- NCT02091934
- Testing
- Wavefront-guided PRK, Wavefront-optimized PRK
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Stanford University
Sacroiliac Joint Pain
High-intensity Laser Therapy for Sacroiliac Joint Pain
Effect of high intensity laser on sacroiliac joint pain
- Trial name
- Girls (NCT06262763)
- Testing
- Laser Therapy, Traditional exercises
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Aged Skin
Determination of Safety and Efficacy of a Laser With Cooling for Treatment of Skin
The appearance of aged skin is a common cosmetic complaint of middle aged and older individuals. This study evaluates the safety and efficacy of a new laser with cooling to improve the appearance of aged skin.
- Trial name
- NCT00323921
- Testing
- dermatological infrared laser
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Candela Corporation
Must be PRK Candidate
A 6 Month Study to Evaluate the Safety, Analgesic Efficacy of ACUVAIL™ (Ketorolac Tromethamine Ophthalmic Solution) 0.45%, in Post-PRK Corneal Wound Healing
STUDY OBJECTIVE: To evaluate the safety and efficacy of Acuvail 0.45% administered BID for increasing corneal re-epithelialization, decreasing the time to zero pain in post-photorefractive keratectomy (PRK) surgery, and PRK…
- Trial name
- NCT01193231
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Durrie Vision
Periodontal Inflammation
The Effect of Low-Level Laser Therapy as an Adjunct to Non-surgical Therapy in Different Age Groups
the summary is to evaluate The Effect of Low-Level Laser Therapy as an Adjunct to Non-surgical Therapy on Inducible Nitrous Oxide Synthase Salivary Levels in Different Age Groups of Chronic Periodontitis Patients
- Trial name
- NCT06140394
- Testing
- diode laser, non surgical scaling
- Where
- 2 sites in Egypt
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Faculty of Dental Medicine for Girls
Genitourinary Syndrome of Menopause (GSM), Vaginal Dryness
To Assess Signs and Symptoms in Women Affected by GSM After One Cycle of Pixel CO2-Alma Fractionated Laser
Genitourinary syndrome of menopause (GSM) occurs in approximately 50% of menopausal women but is both underrecognized and undertreated despite numerous treatment options.
- Conditions
- Genitourinary Syndrome of Menopause (GSM), Vaginal Dryness, Burning, Pain
- Trial name
- NCT05156502
- Testing
- Fractionated Laser (Pixel CO2-Alma), Fractionated Laser (Pixel CO.2-Alma)
- Where
- Italy
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Dr. Filippo Murina
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