Clinical trials: Lasers
Fat Atrophy
Clinical Evaluation of the Safety and Efficacy of a 1060nm Diode Laser (Abdomen)
This study is evaluating a 1060nm diode laser for non-invasive fat reduction of the abdomen. The study will enrolled up to 50 subjects requesting non-invasive lipolysis of the abdomen.
- Trial name
- NCT03756350
- Testing
- 1060nm diode laser
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Venus Concept
Musculoskeletal Pain
Evaluation of Erchonia PPL Laser as a Pretreatment Adjunct to Enhance Standard Erchonia Red Laser for the Relief of Pain
This study is to see if applying pre-treatment with the Erchonia® PPL blue laser therapy, followed sequentially with the standard Erchonia red laser therapy can help reduce nociceptive musculoskeletal pain
- Trial name
- NCT07121933
- Testing
- Erchonia® PPL blue laser therapy, followed sequentially with the standard Erchonia red laser therapy
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Erchonia Corporation
Branch Retinal Vein Occlusion
Efficacy and Safety of Ranibizumab With or Without Laser in Comparison to Laser in Branch Retinal Vein Occlusion
This study will generate comparative data for 0.5-mg ranibizumab using PRN dosing administered with or without adjunctive laser treatment versus laser photocoagulation (the current standard of care) up to Month 6 in patients with…
- Trial name
- BRIGHTER (NCT01599650)
- Testing
- Ranibizumab, Laser
- Where
- 82 sites in Australia, Canada and 15 more
- Volunteers
- 455 people
- Sponsor
- Novartis Pharmaceuticals
HYPERHIDROSIS
Investigation of Hyperhidrosis Treatment Using the Nd: YAG 1440nm Wavelength Laser
The purpose of this study is to evaluate the safety and efficacy of the Nd:YAG 1440 nm wavelength laser for the treatment of primary hyperhidrosis of the axilla.
- Trial name
- NCT01810991
- Testing
- Nd:YAG Laser
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Cynosure, Inc.
Psoriasis
Acitretin or Tazarotene Gel and Excimer Laser for Treatment of Psoriasis
This is a randomized, double-blind study of excimer (308-nm UVB) laser added to either tazarotene 0.1% gel or acitretin 25 mg daily for plaque psoriasis.
- Trial name
- NCT01094717
- Testing
- Acitretin 25Mg Oral Capsule, Excimer laser, Tazarotene 0.1% Gel,Top
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of Utah
Esophageal Neoplasms
A Diagnostic Study of the Advanced Endoscopy to Detect Early Esophageal Cancer
This descriptive cross sectional study aims to directly compare the diagnostic capability of the probed-based confocal laser endomicroscopy (pCLE) and the magnifying narrow band imaging (M-NBI) in the Lugol's voiding lesions.
- Trial name
- NCT02182804
- Testing
- Olympus, Cellvizio
- Volunteers
- 44 people
- Sponsor
- King Chulalongkorn Memorial Hospital
Myopia, Hyperopia
Safety and Efficacy Study of Topography-Guided LASIK to Treat Myopia and Hyperopia
This purpose of this study is to evaluate the safety and effectiveness of a topography-based custom ablation treatment using the ALLEGRETTO WAVE® Eye-Q 400 Hz laser system for treating myopia and hyperopia.
- Trial name
- NCT01028378
- Testing
- T-CAT topography-guided LASIK treatment with the Allegretto Wave Eye-Q 400 Hz Excimer Laser
- Where
- 10 sites in United States
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- Clinical Research Consultants, Inc.
Tattoo Removal
Multi-Wavelength Laser Tattoo Removal Pivotal Study
Multi-center study to evaluate the safety and efficacy of an investigational version of the Cutera enlighten laser that offers multiple wavelengths for tattoo removal
- Trial name
- NCT02935660
- Testing
- enLighten Laser
- Where
- 2 sites in United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Cutera Inc.
Healthy
Effectiveness of Two Different Doses of BI 1026706 on the Overall Peak-to-Peak (PtP) N2/P2-component Amplitude of Laser (Somatosensory, Radiant-heat) Evoked Potentials (LEP) in UVB(Ultraviolet)-Irradiated Skin in Healthy Male Volunteers
To investigate the influence of different doses of BI 1026706 on the primary endpoint (PtP-amplitude LEP in UV skin) compared to placebo. The comparison of both doses of BI 1026706 to celecoxib in the UVB treatment.
- Trial name
- NCT02037165
- Testing
- Pregabalin, BI 1026706, Celecoxib
- Where
- Germany
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Diabetic Retinopathy, Macula Edema
Transfoveal Micropulse Laser for Center Involving Diabetic Macular Edema
Anti-vascular endothelial growth factor (VEGF) therapy is currently the mainstay of treatment for diabetic macular edema (DME). One of the main obstacles of anti-VEGF therapy is the need of repeated injections, which carries both…
- Trial name
- NCT04359771
- Testing
- Yellow micro-pulse laser, Diode micro-pulse laser
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Cairo University
Renal Stone
High Versus Low Power Settings During Ureteroscopic Laser Lithotripsy
The primary aim of the study is to compare the operative times following ureteroscopic lithotripsy for renal stones with Thulium Fiber Laser using low and high power settings.
- Trial name
- NCT05697250
- Testing
- Laser power settings (Thulium Fiber Laser)
- Where
- Norway
- Volunteers
- 150 people
- Sponsor
- Haukeland University Hospital
Photobiomodulation Therapy, Photomedicine
Photomedicine Project 14: PBMT for Performance Enhancement in SOF
Special Operations Forces (SOF) train continually to maintain peak performance. Thus, they are nearly always in a state of recovery, and in need of noninvasive therapies to address the taxing workload.
- Conditions
- Photobiomodulation Therapy, Photomedicine, Low-Level Laser Therapy, Performance Enhancement
- Trial name
- SOF (NCT06380179)
- Testing
- THOR3 training + Photobiomodulation Therapy (PBMT)
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Musculoskeletal Injury Rehabilitation Research for Operational Readiness
Kidney Stone, Renal Stone
Comparison of Laser Lithotripsy With and Without Steerable Ureteroscopic Renal Evacuation (SURE)
The purpose of the study is to compare the effects, good and/or bad, of a treatment for removing kidney stones called the SURE procedure for stone evacuation to the standard treatment using a basket for stone removal.
- Conditions
- Kidney Stone, Renal Stone, Urolithiasis
- Trial name
- NCT04519294
- Testing
- SURE, Standard Ureteroscopy (Basketing)
- Where
- 11 sites in United States
- Volunteers
- 132 people
- Sponsor
- Calyxo, Inc.
Astigmatism, Cataract
Femtosecond Laser Assisted Keratotomies for the Management of Corneal Astigmatism
A cataract is a clouding of the lens that occurs naturally with age. Cataract surgery involves removal of the cloudy lens and replacement with an artificial one.
- Trial name
- NCT04676451
- Testing
- Femto-AK
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- Milton S. Hershey Medical Center
Facial Solar Lentigines
Study for the RevLite Laser System for Facial Solar Lentigines
The purpose of this study is to evaluate the effects of the Revlite Laser System for treatment of facial solar lentigines
- Trial name
- NCT02110108
- Testing
- Revlite Laser System
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Cynosure, Inc.
Venous Insufficiency
Safety and Efficacy of Endovenous Laser Ablation for the Resolution of Incompetent Perforator Veins
This trial is designed as a prospective, non randomized, single center clinical trial to determine the safety and efficacy of laser ablation of incompetent perforator veins.
- Trial name
- RELIEVE (NCT00565604)
- Testing
- Short Catheter Delivery
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Vascular Solutions LLC
Diabetic Macular Edema
A 12 Month Core Study to Assess the Efficacy and Safety of Ranibizumab (Intravitreal Injections) in Patients With Visual Impairment Due to Diabetic Macular Edema and a 24 Month Open-label Extension Study
CRFB002D2301: The core study was designed to confirm the efficacy and safety of ranibizumab (0.5 mg) as adjunctive therapy when added to laser photocoagulation and/or mono-therapy in patients with visual impairment due to…
- Trial name
- RESTORE (NCT00687804)
- Testing
- Ranibizumab, Laser
- Where
- 13 sites in Australia, Belgium and 11 more
- Volunteers
- 345 people
- Sponsor
- Novartis
Pleural Carcinomatosis
Probe Based Confocal Laser Endomicroscopy During Thoracoscopy for Pleural Malignancies Diagnosis.
Probe based confocal laser endomicroscopy (pCLE) is a new optical endoscopic technique, generating fluorescent light emission from the tissue of interest and allowing in vivo live imaging at a cellular level ("optical biopsies").
- Trial name
- NCT03805971
- Testing
- Study of the pleural cavity with a confocal laser endomicroscope.
- Where
- Belgium
- Volunteers
- 65 people
- Sponsor
- University of Liege
Ecchymosis
Effects of Topical Vitamin K, Vitamin K and Retinol, and Arnica on Post-Laser Bruising
The objective of this study is to assess the comparative utility of topical formulations in hastening the resolution of skin bruising.
- Trial name
- NCT00363038
- Testing
- Petrolatum United States Pharmacopeia (USP), Vitamin K and retinol ointment, Arnica ointment
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Burn Scars
Fractionated Carbon Dioxide Laser and Burn Scar Contractures: Evaluation of Post-Treatment Scar Function and Appearance
The investigators are studying the appearance and function of burn scars after treatment with fractionated carbon dioxide laser.
- Trial name
- NCT02115646
- Testing
- fractionated carbon dioxide laser
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Massachusetts General Hospital