Clinical trials: Lasers
Diabetic Macular Edema
Grid Laser for Diffuse Diabetic Maculopathy
Diabetic related complications are increasing day by day due to increse in the number of diabetic patients all over the world. Diabetic macular edema is one of them and a major cause of vision imparment.
- Trial name
- MMG (NCT02555956)
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Dow University of Health Sciences
Asthma
Development of a Breath Analyzer for Asthma Screening
Annually, asthma is responsible for 1 million emergency room visits, 400,000 hospitalizations, and 5000 deaths according to the NHLBI.
- Trial name
- NCT00386737
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Ekips Technologies
Irritable Bowel Syndrome, Inflammatory Bowel Disease
Assessment of Small Intestinal Bowel Epithelial Gaps in Irritable Bowel Syndrome
The study aims to: 1. Determine whether the density of epithelial gaps in terminal ileum of patients with irritable bowel syndrome (IBS) is different from that in inflammatory bowel disease (IBD) patients and normal controls by…
- Trial name
- NCT01632488
- Where
- China
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Shandong University
Acne Vulgaris, Scars
Erbium-YAG Laser Versus Platelet Rich Plasma in the Treatment of Atrophic Acne Scars
This study aim to assess the efficacy of Er-YAG laser 2940nm and PRP as a single line of treatment in comparison with combined treatment in atrophic post acne scars.
- Trial name
- NCT03933033
- Testing
- Fractional Erbium Yağ Laser, Platelet Rich Plasma
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Aswan University Hospital
Diabetic Foot Ulcer (DFU)
Low-level Laser Therapy Versus Offloading Exercises on Foot Ulcer Healing in Patients with Type 2 Diabetes
The goal of this clinical trial is to evaluate the effect of extravascular Low-level laser therapy (LLLT) versus offloading exercises on foot ulcers healing (DFUs) in type 2 diabetic patients.
- Trial name
- NCT06670417
- Testing
- Low level laser therapy watch: The laser watch device was a semiconductor LLL therapeutic apparatus, (model:SL-03 GaALAs semiconductor) Domer Laser Therapy Watch class 3B 650nm low-level laser light, Buerger Allen exercise, Regular wound care
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Apical Periodontitis, Endodontically Treated Teeth
Effect of Photobiomodulation on Pain and Healing of the Vertical Releasing Incision After Endodontic Microsurgery
The purpose of this study is to evaluate the effect of Photobiomodulation (PBM) in postoperative pain after endodontic microsurgery (EMS) in patients from the University of Texas Health Science Center at Houston, School of…
- Conditions
- Apical Periodontitis, Endodontically Treated Teeth, Endodontic Disease, Apical Cyst
- Trial name
- NCT06574152
- Testing
- PBM treatment, EMS
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- The University of Texas Health Science Center, Houston
Malocclusion, Orthodontic Tooth Movement
Micro-osteoperforation Versus Photobiomodulation Therapy for Accelerating Maxillary Canine Retraction
Orthodontic treatment often requires moving the upper canine teeth (the pointed teeth) into the spaces left after removing premolar teeth.
- Conditions
- Malocclusion, Orthodontic Tooth Movement, Maxillary Canine Retraction
- Trial name
- MOP-PBMT (NCT07658235)
- Testing
- Micro-osteoperforation (MOP), Photobiomodulation Therapy using 976 nm Diode Laser, Conventional orthodontic canine retraction
- Where
- Iraq
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Kufa University
Hashimoto Thyroiditis, Thyroiditis
Effect of Photobiomodulation Therapy in Patients With Hashimoto's Thyroiditis
The standard lifelong treatment for Hashimoto's thyroiditis (HT), a chronic autoimmune disease, is levothyroxine (LT4) therapy. Despite LT4 replacement therapy, patients continue to experience persistent fatigue, deterioration in…
- Trial name
- NCT06735040
- Testing
- Photobiomodulation Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul Medipol University Hospital
Lepromatous Leprosy
Microcirculatory Impairment in Patients With Leprosy
In this study the investigators have aimed to evaluate morphology and reactivity of cutaneous microcirculation in patients with lepromatous leprosy.
- Trial name
- NCT02085317
- Testing
- acetylcholine Iontophoresis, sodium nitroprusside Iontophoresis
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Curt Treu
Skin Injury
The Novel Electrolyzed Water Spray Treatment Discomfort, Redness and Swelling of the Skin Surrounding the Wound
The purpose of this study is to test whether the reduction of the sense of discomfort and redness and swelling of the skin surrounding the wound of patients by use of the novel electrolyzed water spray will relieve the…
- Trial name
- NCT05792306
- Testing
- The novel electrolyzed water spray, The saline spray
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Dove Medical Press Ltd
Melasma
Combination Topical Cysteamine and Fractional 1927nm Low-Powered Diode Laser for Treatment of Facial Melasma
The primary objective of our study is to determine the efficacy of combined topical cysteamine cream with a 1927 diode non-ablative laser (Clear + Brilliant Permea®; Solta Medical, Inc.), compared to topical cysteamine (Cyspera)…
- Trial name
- NCT05656833
- Testing
- Fractional 1927nm Low-Powered Diode Laser, Topical Cysteamine
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- UnionDerm
Acne Scars - Mixed Atrophic and Hypertrophic
Safety and Efficacy Investigation on the Effects of ClearSkin Non-ablative ER:Glass 1540nm Laser Module in the Treatment of Acne Scars.
The ClearSkin module, Er: Glass 1540nm, is largely used in the treatment of acne vulgaris and acne scars. The non-ablative ER:Glass 1540 nm laser deeply penetrates the skin, causing thermal damage to the sebaceous glands…
- Trial name
- NCT06102343
- Testing
- Alma Harmony
- Where
- Portugal
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Alma Lasers
Cataract With a Nuclear Sclerosis Grade Between 1 to 3
Zero CDE Technique for Lens Removal During FLACS
The Zero CDE (cumulative dissipated energy) technique facilitates cataract removal with no or minimal phaco energy. This is facilitated by a femtosecond laser, which pre-divides the cataractous lens nucleus into multiple small…
- Trial name
- NCT07404293
- Testing
- Femtosecond laser-assisted cataract surgery using Zero CDE
- Where
- Canada
- Volunteers
- 90 people
- Sponsor
- Bochner Eye Institute
Heart Arrhythmia
Acu Tens Versus Low Level Laser After Open Heart Surgeries
Increase in heart rate (HR) is a normal sympathetic response to body trauma and a common consequence of major surgical procedures,A high resting HR is associated with increased myocardial work that may be detrimental to patients…
- Trial name
- NCT06637085
- Testing
- LLLT, traditional physical therapy, ACU TENSE
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Liver Percutaneous Biopsy or Ablation, Kidney Percutaneous Biopsy or Ablation
Needle-based Confocal Laser Endomicroscopy in CT-guided Percutaneous Procedures
This study is a prospective study in order to demonstrate the technical feasibility and safety of doing endomicroscopic imaging during interventional radiology procedure in two main indications: Kidneys and liver.
- Trial name
- NCT02288104
- Testing
- needle based confocal endomicroscopy
- Where
- France
- Volunteers
- 16 people
- Sponsor
- Mauna Kea Technologies
Bladder Cancer
Laser En Bloc Resection Of Bladder Tumor (HoLERBT) VS. Conventional Transurethral Resection Of Bladder Tumors (cTURBT)
Randomized clinical trial aiming to assess Holmium Laser En Bloc Resection Of Bladder Tumor (HoLERBT) in comparison with Conventional Transurethral Resection Of Bladder Tumors (cTURBT) in tumor histopathological staging quality…
- Trial name
- HoLERBT (NCT02555163)
- Testing
- HoLERBT, cTURBT
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Diabetic Macular Oedema
Aflibercept anD navigateD vErsus coNvensional Laser in Diabetic macUlar edeMa
Diabetic macular edema (DME) in diabetic retinopathy (DR) is the leading cause of visual impairment among the 300,000 Danish patients with diabetes (DM) and will in time affect 29% of patients.
- Trial name
- ADDENDUM (NCT02554747)
- Testing
- Navigated laser, Conventional laser
- Where
- Denmark
- Volunteers
- 48 people
- Sponsor
- Odense University Hospital
Atrophic Acne Scar
Fractional CO2 Laser Combined With PRP Fluid Versus Gel in Treatment of Acne Scars
This study is to test the efficacy of fractional laser combined with either PRP fluid or PRP gel in the treatment of atrophic acne scars
- Trial name
- PRP (NCT04580758)
- Testing
- Fractional laser with PRP fluid or PRP gel
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Yasmine Ahmed Abd El-Maguid El-Hadidy
Port-Wine Stain
Retrospective Cohort Study on the Impact of PDL Treatment History on the Efficacy of HMME-PDT in Treating PWS Children
This retrospective study investigated the influence of prior pulse dye laser (PDL) treatment on the effectiveness of Hemoporfin-PDT in young children aged 1-3 years with PWS.
- Trial name
- NCT06875492
- Testing
- HMME-PDT, PDL
- Where
- China
- Volunteers
- 273 people
- Sponsor
- Second Affiliated Hospital of Xi'an Jiaotong University
Pilonidal Sinus
Prospective Study in Laser Treatment of Pilonidal Cysts
The goal of this observational study is to evaluate the recurrence rate after laser treatment of pilonidal sinus within two years of the procedure in adult patients who require this procedure to treat their pilonidal sinus.
- Trial name
- LASPRO (NCT07314632)
- Where
- 2 sites in France
- Volunteers
- 240 people
- Sponsor
- Centre Hospitalier Departemental Vendee
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