Clinical trials: Lasers
Vitiligo
Evaluation of Human Melanocytes After the Use of PRP Versus Fractional CO2 Laser in Vitiligo
Vitiligo is considered the most common chronic depigmentation disorder that affects around 0.5 -2% of the world population . In Africa , its prevelance is around 0.4% and 1.22 % in Assiut .
- Trial name
- PRP (NCT04320160)
- Testing
- Platelet rich plasma, Fractional CO2 laser
- Volunteers
- 30 people
- Sponsor
- Assiut University
Skin Quality
Laser Treatment to Improve Skin Quality
To assess the efficacy of a 1064nm picosecond laser (PicoWay; Candela; Marlborough, MA) with diffractive lens array and a picosecond 755nm laser (PicoSure®; Cynosure®; Westford, MA) with diffractive lens array in subjects for the…
- Trial name
- NCT05595525
- Testing
- 1064NM pico Laser, 755NM pico Laser
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Goldman, Butterwick, Fitzpatrick and Groff
Autoregulation
Regulation of Choroidal Blood Flow During Combined Changes in Intraocular Pressure and Arterial Blood Pressure
Autoregulation is the ability of a vascular bed to maintain blood flow despite changes in perfusion pressure. For a long time it had been assumed that the choroid is a strictly passive vascular bed, which shows no autoregulation.
- Trial name
- NCT00812526
- Testing
- Suction cup application, Squatting
- Where
- Austria
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Lumbar Radiculopathy, Hoffman's Reflex
High-power Laser Versus Pulsed Electromagnetic Therapy in Lumbar Radiculopathy.
To compare between high-power laser versus pulsed electromagnetic therapy on pain and Hoffman reflex in lumbar radiculopathy.
- Conditions
- Lumbar Radiculopathy, Hoffman's Reflex, Pulsed Electromagnetic Therapy, Laser Therapy
- Trial name
- NCT07393750
- Testing
- high-power laser, Pulsed electromagnetic field, physiotherapy program
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Apical Periodontitis
Laser-Activated Versus Passive Ultrasonic Irrigation in Endodontic Retreatment
This study will compare three methods of activating the final irrigation solution in reducing living bacteria inside the root canals of teeth that require root canal retreatment because of apical periodontitis, an inflammatory…
- Trial name
- NCT07903285
- Testing
- Photon-Induced Photoacoustic Streaming, Shock Wave Enhanced Emission Photoacoustic Streaming, Passive Ultrasonic Irrigation
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Inonu University
Tattoo Skin Markers
YAG Laser Versus Punch Biopsy for the Treatment of Tattoo Skin Markers
The purpose of the study is to compare patient satisfaction, clinical efficacy and adverse effects of Q-switched YAG laser versus punch biopsies for the treatment of tattoo dots that are applied as skin markers in relation to…
- Trial name
- NCT00271674
- Testing
- Q-switched YAG laser
- Where
- Denmark
- Sponsor
- Bispebjerg Hospital
Tattoo Removal
Split-tattoo Study Comparing the Safety and Efficacy of 670nm Picosecond Laser Versus 755 nm for Tattoo Removal
Study to evaluate safety and efficacy of treatment with the investigational Cutera enlighten laser for tattoo removal as compared to treatment with the Cynosure PicoSure laser
- Trial name
- NCT02912507
- Testing
- Cutera enlighten laser, CynoSure PicoSure 755nm laser
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Cutera Inc.
Non-Small-Cell Lung Carcinoma, Head and Neck Squamous Cell Cancer
LIFE-Lung Bronchoscopy in Patients at Risk for Developing Lung Cancer
The purpose of the study is to evaluate the usefulness and accuracy of the "LIFE-Lung Bronchoscopy" to identify early changes in lung tissues that show precancerous, cancer in situ (just beginning and not spread) and microscopic…
- Conditions
- Non-Small-Cell Lung Carcinoma, Head and Neck Squamous Cell Cancer, Pulmonary Disease, Chronic Obstructive
- Trial name
- NCT00260598
- Testing
- LIFE Bronchoscopy
- Where
- United States
- Volunteers
- 142 people
- Sponsor
- University of Pittsburgh
Stable Vitiligo
Melanocyte Transplantation for Patients With Stable Vitiligo.
Vitiligo is an acquired skin disease that significantly impacts the quality of life of patients. Medical treatment of vitiligo includes the use of melanocyte transplantation but the results are variable.
- Trial name
- NCT01701648
- Testing
- Laser CO2
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Frenulum; Hypertrophy
Pain Perception and Wound Healing After Laser-assisted Frenectomy in Children
This study is based on the records of the patients treated for labial frenectomy with a dental laser at the Department of Padiatric Dentistry from January 2017 to December 2017.
- Trial name
- NCT04368715
- Testing
- Laser-assisted frenectomy with 2780 nm Er:Cr;YSGG and 940 nm diode laser
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Trakya University
Myopia
Evaluation of Conventional Photorefractive Keratectomy (PRK) in U.S. Army Personnel, Substudy of: Initial Evaluation of Excimer Laser Keratorefractive Surgery in U.S. Army Personnel
The purpose of this study is to: 1. evaluate the safety and efficacy of conventional PRK in U.S. Army personnel who have naturally occurring myopia with or without astigmatism. 2.
- Trial name
- NCT00412568
- Testing
- Photorefractive Keratectomy (PRK)
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Walter Reed Army Medical Center
Salt; Excess
Dietary Salt and Microvascular Function
It is well accepted that high-salt (HS) intake is an essential risk factor in development and progression of hypertension. Results of some recent studies suggest that some of the deleterious effects of a HS diet are independent…
- Trial name
- NCT02727426
- Testing
- Low Salt (LS) diet, High Salt (HS) diet
- Where
- Croatia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Josip Juraj Strossmayer University of Osijek
Pain Management
LASER Effects Blood Flow
This study investigate the potential impact of low power laser (LPL), an non-invasive physical therapy, on the cardiovascular system by focusing on its effect on heart rate and autonomic tone.
- Trial name
- LASERBF (NCT07369843)
- Testing
- physical therapy (low power LASER)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Saint Paul's Hospital, Congregation Of The Sisters Of Saint Paul De Chartres
Vitiligo
Excimer Lamp Versus Excimer Laser in Vitiligo Treatment
308 nm excimer lamp and 308 nm excimer laser have both provide interesting results in treating vitiligo. They have the same wavelength but the type of emission of the photons is different.
- Trial name
- NCT00696358
- Testing
- 308nm excimer lamp, 308nm excimer laser
- Where
- France
- Sponsor
- Centre Hospitalier Universitaire de Nice
Halitosis
Laser Tongue Debridement for Oral Malodor
Malodor is a multifactorial condition with oral pathology representing the main culprit and the tongue being the first to second contributor to the malodor.
- Trial name
- NCT04120948
- Testing
- Waterlase Express Laser System, Tongue scraper
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- New York Head & Neck Institute
Acne Scars - Mixed Atrophic and Hypertrophic
enLighten Laser With MLA Handpiece for Treatment of Moderate and Severe Acne Scars
The purpose of this pivotal investigation is to evaluate the efficacy and safety of the Cutera enlighten multi-wavelength 532 nm and 1064 nm Nd:YAG picosecond pulse duration laser and an investigational micro-lens array (MLA)…
- Trial name
- NCT03284333
- Testing
- other
- Where
- 2 sites in United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Cutera Inc.
Knee Osteoarthritis (Knee OA)
High-Intensity Laser Therapy (HILT) in Patients With Knee Osteoarthritis
This randomized placebo-controlled trial aims to evaluate the effectiveness of High-Intensity Laser Therapy (HILT) as an adjunct to standard outpatient physiotherapy in patients with knee osteoarthritis.
- Trial name
- NCT07661407
- Testing
- Conventional Physiotherapy, High-Intensity Laser Therapy (HILT)
- Volunteers
- 72 people
- Sponsor
- University of Rzeszow
Atrophy of Edentulous Mandibular Alveolar Ridge
Treatment Outcome of Short Implant Assisted Mandibular Overdenture
This study evaluates the use of short dental implants to support mandibular overdenture together with the use of laser therapy for treatment of patients with atrophic ridges.
- Trial name
- NCT03540316
- Testing
- Two short implants and 2 minutes LLLT, Two short implants and 4 minutes LLLT, Four short implants and 2 minutes LLLT
- Where
- Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Sara Zayed
Colitis, Ulcerative
Confocal Laser Endomicroscopy Findings in Patients With Proctosigmoiditis Before and After Initiation of Treatment
Confocal laser endomicroscopy (CLE) is a novel method in evaluation of microscopic structures in vivo. The examination is carried out with a confocal laser endomicroscope, which is either part of the endoscope (manufactured by…
- Trial name
- NCT01684514
- Testing
- Confocal laser endomicroscopy
- Where
- 2 sites in Denmark
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Herlev Hospital
Treatment of Refractory Glaucoma
Comparison of Outcome and Effectiveness Between Micropulse Diode Laser Cyclophotocoagulation and Cyclocryoablation in Treatment of Refractory Glaucoma
laucoma having bad prognosis after maximally tolerated medication,glaucoma that fails after filtering operations, neovascular glaucoma, glaucoma following vitrectomy and glaucoma secondary to uveitis etc.
- Trial name
- NCT05437614
- Testing
- Micropulse diode laser cyclophotocoagulation in treatment of refractory Glaucoma, Cyclocryoablation in treatment of refractory Glaucoma
- Where
- Pakistan
- Volunteers
- 47 people
- Sponsor
- University of Health Sciences Lahore
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