Clinical trials: Lasers
Carcinoma of Glottis
Quality of Life After Laser Cordectomy in Early Glottic Cancer
Laryngeal cancer is common in the Taiwanese populations. Before early 80's, open laryngectomy was the suggested treatment modality for laryngeal cancer.
- Trial name
- NCT02184403
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Chang Gung Memorial Hospital
Pulp and Periapical Tissue Disease, Pulp Necroses
The Efficacy of Laser in Root Canal Disinfection
The aim of this study is to assess in vivo the efficacy of Er,Cr:YSGG/diode laser and Diode/EDTA on bacterial count in root canal treatment in an evidence-based clinical trial.
- Conditions
- Pulp and Periapical Tissue Disease, Pulp Necroses, Pulp; Granuloma
- Trial name
- NCT05964686
- Testing
- Conventional group (NaOCl/EDTA), Dual laser group (Er,Cr:YSGG/Diode):, Combined group (EDTA/Diode):
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Low Back Pain
Effect of Ultrasound and Laser in Chronic Low Back Pain: Randomized Double-blinded Controled Trial
The low level laser therapy has a better effect in decrease the pain than ultrasound therapeutic.
- Trial name
- NCT02210520
- Testing
- pulsatile ultrasound, continuous ultrasound, laser
- Where
- Brazil
- Volunteers
- 22 people
- Sponsor
- University of Sao Paulo General Hospital
Myofascial Pain Syndrome
Effects of Extracorporeal Shock Wave Therapy and Low Level Laser Therapy in Myofascial Pain Syndrome
This study evaluates the effects of low level laser therapy and extracorporeal shock wave therapy in patients with myofascial pain syndrome of the upper trapezius.
- Trial name
- NCT03436459
- Testing
- Extracorporeal Shock Wave Therapy, Low Level Laser Therapy
- Where
- Hungary
- Volunteers
- 60 people
- Sponsor
- Petz Aladar County Teaching Hospital
Glaucoma
Benchmarking Management of Glaucoma Using the Diopsys VEP/PERG Protocols.
Establish electrophysiological benchmarks, using the Diopsys Visual Evoked Potential/ Pattern ERG (VEP/PERG) protocols of populations with Glaucoma following: 1) Baseline VEP/ERG prior to treatment; and 2) VEP/PERG after…
- Trial name
- NCT02594280
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Diopsys, Inc.
Dental Caries
Fissure Caries Inhibition Study With Solea CO2-9.3μm Short-pulsed Laser
The objective of this clinical study is to evaluate whether the use of the new CO2 - 9.3μm short-pulsed laser increases the caries resistance of occlusal pit and fissure surfaces in patients in addition to fluoride therapy.
- Trial name
- LaserFissure (NCT02357979)
- Testing
- Laser, Fluoride
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Wrinkle, Rosacea
Evaluation of Cutera Excel V™ Laser With Green Genesis and Micro-Lens Array (MLA)Attachment
Evaluate the Cutera excel V™ Laser with Green Genesis and a Micro-Lens Array (MLA) Attachment
- Conditions
- Wrinkle, Rosacea, Scarring
- Trial name
- NCT03424304
- Testing
- Excel V™ Laser With Green Genesis
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cutera Inc.
Probe-based Confocal Laser Endomicroscopy, Artificial Intelligence
Automatic Classification of Colorectal Polyps Using Probe-based Endomicroscopy With Artificial Intelligence
Probe-based confocal laser endomicroscopy (pCLE) is an endoscopic technique that enables real-time histological evaluation of gastrointestinal mucosa during ongoing endoscopy examination.
- Conditions
- Probe-based Confocal Laser Endomicroscopy, Artificial Intelligence, Colorectal Polyps
- Trial name
- NCT03787784
- Testing
- AI presentation
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Shandong University
Unwanted Fine Facial Hair
Clinical Evaluation to Assess the Safety and Efficacy of GentleMax Pro™/GentleMax Pro Plus™
This clinical study is intended to evaluate the safety and efficacy of the GentleMax Pro Plus™ laser system for its intended use of hair removal while using short pulse durations to improve the efficacy of achieving permanent…
- Trial name
- NCT04975243
- Testing
- GentleMax Pro Plus 755nm and 1064nm laser system
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Candela Corporation
Periodontitis, Smokers
This a Clinical Trial to Evaluate the Efficacy of I-PRF, Povidone-Iodine and Laser as Adjuncts to Non-surgical Periodontal Treatment in Smokers and Non-Smokers Periodontitis Patients
This study is a randomized, controlled, split-mouth clinical trial designed to evaluate and compare the effectiveness of four different subgingival adjuncts used along side standard Scaling and Root Planning (SRP).
- Conditions
- Periodontitis, Smokers, Non Smokers, Periodontal Disease
- Trial name
- NCT07707063
- Testing
- Injectable Platelet-Rich Fibrin (I-PRF), Diode Laser Activation, Povidone-Iodine Irrigation (1%)
- Where
- Tunisia
- Volunteers
- 50 people
- Sponsor
- Military Hospital of Tunis
Keratosis Pilaris
Long-pulsed 1064 nm Nd-YAG Laser Versus TCA 20% in Treatment of Keratosis Pilaris
Keratosis pilaris (KP) is a common disorder of keratinization. There are different treatment modalities for KP with variable results.
- Trial name
- NCT04797663
- Testing
- Nd-YAG laser, TCA 20%
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Cairo University
Peripheral Pulmonary Lesions
Optical Biopsy for Peripheral Pulmonary Lesions
The purpose of the study is to describe confocal laser endomicroscopy (CLE) interpretation criteria for different types of peripheral pulmonary lesions (PPLs), with histopathological correlation, and to perform the validation of…
- Trial name
- NCT06457087
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Shanghai Chest Hospital
Prostate Cancer
Focal Laser Ablation of Prostate Tissue
This is an open-label pilot, feasibility/exploratory study to evaluate the safety of laser interstitial thermal therapy (LITT) using Visualase in the focal ablation of prostate tissue and to gather data for the design of future…
- Trial name
- FLA (NCT02357121)
- Testing
- Focal Laser Ablation
- Where
- 2 sites in United States
- Volunteers
- 11 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Laxity; Skin
Efficacy and Safety of Fractional 1064-nm Picosecond Laser for Facial Skin Tightening
The goal of this clinical trial is to learn the efficacy and safety of fractional 1064-nm picosecond laser for facial skin tightening.
- Trial name
- NCT06231914
- Testing
- StarWalker® PQX
- Where
- Thailand
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Varicose Veins
Market Penetration of Laser Therapy in Venous Surgery: Ziekenhuis Oost-Limburg - Ziekenhuis Maas En Kempen Center Experience
The goal of this registry is to evaluate the indication for EndoVenous Laser Ablation (EVLA) therapy. Can this be enhanced? What are the reasons for not using the laser? Therefore, this study aims to define clear indications for…
- Trial name
- NCT03856814
- Testing
- ELVeS® Radial® 2ring slim fiber used for EndoVenous Laser Ablation
- Where
- Belgium
- Volunteers
- 500 people
- Sponsor
- Duomed
Glaucoma
A Trial of China Laser and Surgery Study Glaucoma in Rural China
Aims and Objectives (Quantitative) Aim: To compare the effectiveness of selective laser trabeculoplasty with trabeculoplasty in lowering the intraocular pressure in patients with medically uncontrolled open angle glaucoma in…
- Trial name
- NCT02955849
- Testing
- SLT laser
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Sun Yat-sen University
High Grade Glioma
Expedited Laser Interstitial Thermal Therapy + Chemoradiation For Newly Diagnosed High Grade Gliomas
The investigators of this study want to see if shortening the total treatment time for brain tumors is safe.The treatment for participant's brain tumors is laser surgery (Laser Interstitial Thermal Therapy (LITT)) followed by…
- Trial name
- NCT02970448
- Testing
- LITT, Radiation therapy, Temozolomide
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Case Comprehensive Cancer Center
Liver Cirrhoses
Alterations in Intestinal Mucosal Barrier Visualized by Confocal Laser Endomicroscopy in Liver Cirrhosis: a Pilot Trial (AMBIC)
Clinical trial with medical devices. A diagnostic trial conducted to find a better (less invasive) procedure for predicting the onset of spontaneous bacterial peritonitis(SBP), which is a complication of liver cirrhosis with…
- Trial name
- AMBIC (NCT03878563)
- Testing
- Cellvisio 100 Series (fibered confocal microscopic system)
- Where
- 2 sites in Switzerland
- Volunteers
- 26 people
- Sponsor
- Dr.med. Monica Rusticeanu
Orthodontic Appliance Complication, Gingival Overgrowth
Scalpel Versus Laser Gingivectomy in Orthodontic Patients in the Management of Periodontal Health
Patients undergoing orthodontic treatment with fixed appliances usually develop gingival enlargement (GE). Its development is usually attribute to chronic inflammation, and may cause both esthetic and functional problems for the…
- Trial name
- NCT03514316
- Testing
- Scalpel Gingivectomy, Laser Gingivectomy, Nonsurgical periodontal treatment
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- University of Rome Tor Vergata
Radiculopathy, Lumbosacral Region, Radiculopathy Lumbar
The Effect of High-power Laser Therapy on Pain, Functional Disability, Range of Motion and Pressure Pain Threshold in Subjects With Radicular Low Back Pain Due to Intervertebral Disc Herniation
Low back pain is the predominant cause of disability on a global scale. In the year 2015, the worldwide point prevalence of activity-limiting low back pain stood at 7·3%, suggesting that at any given moment, 540 million…
- Trial name
- NCT06151704
- Testing
- High intensity laser therapy, Motor control exercise
- Where
- Iran
- Volunteers
- 36 people
- Sponsor
- Iran University of Medical Sciences
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