Clinical trials: Lasers
Ophthalmological Disorder
Positional Stability and Refractive Behaviour After Implantation of an IOL After Cataract Surgery
The newest generation Lucia 621 has a step vault design that is claimed to provide excellent positional and refractive predictability.
- Trial name
- NCT06069752
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- Johannes Kepler University of Linz
Diabetic Macular Edema
Combination of Intravitreal Ranibizumab With or Without Micropulse Laser for the Treatment of DME
The objective of this study is to evaluate if combination of intravitreal ranibizumab with micropulse laser shows non inferiority compared to intravitreal ranibizumab only in diabetic macular edema.
- Trial name
- NCT03690947
- Testing
- Intravitreal Ranibizumab, Micropulse Laser, Intravitreal Ranibizumab as needed
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Beijing Hospital
Coronary Artery Stenosis
Coronary Laser Atherectomy System for Treatment of Coronary Artery Stenosis (SHINE)
This prospective, multi-center clinical trial evaluates the safety and efficacy of the Coronary Laser Atherectomy System for the pretreatment of coronary artery stenosis.
- Trial name
- SHINE (NCT07697638)
- Testing
- Coronary Laser Atherectomy System, CVX300 Laser System
- Volunteers
- 218 people
- Sponsor
- Shanghai MicroPort Rhythm MedTech Co., Ltd.
Tattoo Removal
Pilot Study of Multi-wavelength Laser for Tattoo Removal
To evaluate the safety and efficacy of an investigational version of the Cutera enLighten laser that offers muliple wavelengths for tattoo removal.
- Trial name
- NCT03290547
- Testing
- Cutera enLighten laser
- Where
- 2 sites in United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cutera Inc.
Skin Tightening of the Mandibular and Sub-mandibular Areas
Mandible and Sub-mandible Using the 1440nm Wavelength Laser and Hand Piece
The purpose of this study is to use the 1440nm Wavelength laser along with the hand piece to provide clinical outcome data for treatment of the mandibular and submandibular areas specifically for skin tightening and laser…
- Trial name
- NCT01813747
- Testing
- 1440 nm wavelength laser with handpiece (Cynosure)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Cynosure, Inc.
Crowding of Anterior Maxillary Teeth
Clear Aligner Treatment With and Without Low Level Laser Therapy for Upper Incisor Crowding
The goal of this clinical trial is to assess the effect of Low Level Laser Therapy (LLLT) on Upper Incisor Crowding using Clear Aligner Treatment (CAT).
- Trial name
- NCT06493721
- Testing
- Clear Aligner Treatment, Low level laser
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Faculty of Dental Medicine for Girls
Refractory Neoplasms
Effectivity and Safety of Endoscopic Ultrasonography-guided Laser Ablation for Refractory Neoplasms
The purpose of this study is to evaluate the safety and efficacy of endoscopic ultrasonography (EUS) guided laser ablation liver, pancreas, and retroperitoneal tumors, the investigators used preoperative and postoperative…
- Trial name
- NCT02816944
- Testing
- EUS-guided laser ablation for refractory neoplasms
- Where
- China
- Volunteers
- 80 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Ureteral Stone
Temperature Profiles During Laser Activation in Ureteroscopic Lithotripsy
The primary aim of this study is to investigate the temperature profiles in the renal pelvis during ureteroscopic Thulium Fiber Laser activation using different settings.
- Trial name
- NCT05677425
- Testing
- Temperature measurement
- Where
- Norway
- Volunteers
- 10 people
- Sponsor
- Haukeland University Hospital
Diabetic Foot Ulcer, Diabetic Foot
Use of Low-level Laser Therapy in the Treatment of Diabetic Foot Ulcers
Diabetes mellitus (DM) is currently an important cause of morbidity and mortality. Global estimates indicate that 382 million people live with diabetes (8.3%), and that number could reach 592 million in 2035.
- Trial name
- NCT04246814
- Testing
- LG1, LG2, LG3
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Federal University of Piaui
Facial Swelling, Pain
Effects of Low-level Laser Therapy After Surgical Removal of Impacted Lower Third Molar
Goal: The aim of this study was to evaluate the effects of low-level laser (LLL) after surgical removal of impacted lower third molars (ILTM).
- Conditions
- Facial Swelling, Pain, Trismus
- Trial name
- NCT04280809
- Testing
- GaAlAs laser
- Where
- Vietnam
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Androgenetic Alopecia
Treatment of Androgenetic Alopecia in Males and Females
The purpose of this study is to evaluate the efficacy of Low Level Laser and Light Therapy system configured in a novel product called the TopHat 655 system, for promoting hair growth in males and females diagnosed with…
- Trial name
- LLLT (NCT01437163)
- Testing
- TopHat 655 rejuvenation system, Laser and/or Light Hair Rejuvenation System
- Where
- 4 sites in United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Apira Science, Inc.
Lumbar Herniated Intervertebral Disc
The Efficacy and Safety of the 1,414 nm Nd:YAG Laser System for Alleviating Back Pain in a Lumbar Disc Patient
This study aims to evaluate the efficacy and safety of the 1,414nm Nd:YAG laser system (ACCUPLASTI) added to Percutaneous Epidural Neuroplasty (PEN), a conventional treatment, to alleviate back pain in a lumbar herniated…
- Trial name
- NCT02598232
- Testing
- 1,414nm Nd:YAG Laser System
- Volunteers
- 30 people
- Sponsor
- CynosureLutronic
Melasma
Fractional co2 Laser Followed by Either Vitamin c or Tranexamic Acid in Treatment of Melasma.
The aim of the study: 1.To compare the efficacy and safety of fractional CO2 laser in combination with vitamin c and tranexamic acid in the treatment of melasma.
- Trial name
- NCT05911698
- Testing
- Fractional co2 laser
- Volunteers
- 25 people
- Sponsor
- Khadija Qenawi
Maxillary Hypoplasia
Orthodontic Retention on the Maxillary Stability After SARME Using Laser Scanner
The objective of this study was to evaluate the effect of the orthodontic retainer on transverse maxillary dental and skeletal stability after SARME.
- Trial name
- NCT01770782
- Testing
- Surgically Assisted Rapid Maxillary Expansion (SARME), Laser Scanner
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Max Domingues Pereira
Anisometropia
Ten-year Follow-up of Laser in Situ Keratomileusis in Patients 8 to 15 Years Old
The purpose of this study is to determine the safety, efficacy, predictability, and stability of laser in situ keratomileusis (LASIK) to correct high anisometropia in patients 8 to 15 years old in whom conventional treatments…
- Trial name
- NCT00800774
- Testing
- LASIK
- Where
- Brazil
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Instituto de Olhos de Goiania
Barrett's Esophagus Without Dysplasia, Barrett's Esophagus With Dysplasia
Volumetric Laser Endomicroscopy With Intelligent Real-time Image Segmentation (IRIS)
This is a prospective randomized clinical trial examining how IRIS (Intelligent Real-time Image Segmentation) affects biopsy patterns in VLE (Volumetric laser endomicroscopy).
- Conditions
- Barrett's Esophagus Without Dysplasia, Barrett's Esophagus With Dysplasia, Barrett's Esophagus With Low Grade Dysplasia, Barrett's Esophagus With High Grade Dysplasia
- Trial name
- NCT03814824
- Testing
- IRIS (Intelligent real-time image segmentation), VLE (Volumetric laser endomicroscopy)
- Where
- 3 sites in United States
- Volunteers
- 148 people
- Sponsor
- Northwell Health
Peripheral Pulmonary Lesions (PPLs)
CLE vs. ROSE for Ex Vivo Lung Biopsy Assessment
The goal of this observational study is to evaluate the diagnostic efficacy of Confocal Laser Endomicroscopy (CLE) compared to Rapid On-Site Evaluation (ROSE) for ex vivo lung biopsy specimens obtained via bronchoscopy.
- Trial name
- NCT07725510
- Testing
- Ex Vivo Confocal Laser Endomicroscopy (CLE) Imaging and Interpretation, Rapid On-Site Evaluation (ROSE) Imaging and Interpretation
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Guangzhou Medical University
Onychomycosis of Toenail
Laser Treatment of Toenail Onychomycosis With a 1064 nm Nd:YAG-laser
This study aims to assess if laser treatment can cure fungal infection in toenails. Nail clippings from eligible subjects were obtained and randomised into two groups.
- Trial name
- NCT05260450
- Testing
- 1064 nm Nd:YAG-laser therapy
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Aalborg University Hospital
Adhesive Capsulitis of Shoulder
Using Large-area Low-level Light Therapy for Treating Adhesive Capsulitis of the Shoulder
Adhesive capsulitis, is a common problem characterized by the insidious onset of glenohumeral pain and limitation of shoulder motion in all planes.
- Trial name
- NCT06004609
- Testing
- Low-level laser therapy (LLLT), Conventional physical therapy
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- National Taiwan University Hospital
Keratoconus, Fuchs Dystrophy
Femtolaser Assisted Keratoplasty Versus Conventional Keratoplasty
This pilot study will compare upto 15 patients undergoing femtolaser assisted keratoplasty (using CE[Conformité Européene] approved femtolaser apparatus) with upto 15 patients undergoing conventional keratoplasty with a manual…
- Conditions
- Keratoconus, Fuchs Dystrophy, Corneal Disease
- Trial name
- NCT03619434
- Testing
- Femtosecond Laser, Trephine blade
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Southampton
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