Clinical trials: Laxity; Skin
Skin Laxity, Wrinkle
Safety and Efficacy of SofWave Treatment to Lift Lax Tissue in the Submental and Neck Zones and to Lift the Eyebrow
This is a prospective, open label, multi-center, self-controlled clinical study to demonstrate the safety and efficacy of SofWave treatment to lift lax tissue in the submental and neck zones and to lift the eyebrow.
- Conditions
- Skin Laxity, Wrinkle, Brow Lifting
- Trial name
- NCT04146584
- Testing
- Sofwave Treatments
- Where
- 5 sites in United States
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Sofwave Medical LTD
Skin Laxity, Skin Aging
Cucurbita Pepo Flowers Extract to Promote Skin Health
The aim of this cosmetic clinical trial is to learn if an extract of Cucurbita pepo flower (CpLfe) works to enhance skin health and resilience in adult women with photo-damage.
- Conditions
- Skin Laxity, Skin Aging, Skin Wrinkling
- Trial name
- EACpLfe22S01 (NCT06674005)
- Testing
- Cucurbita pepo L. Flowers Extract
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ritamaria Di Lorenzo
Skin Laxity, Skin Lines
Improved Skin Anti-aging Outcomes Associated With Collagen Fortified Consumption In 30 to 50-Year-old Women
The goal of this clinical trial is to study the efficacy of collagen supplement on the moisture content and elasticity. 70 participants of 30-50 years old women will be enrolled from two study sites and randomly assigned to use…
- Trial name
- NCT05670977
- Testing
- Study product plus collagen supplement, Study product without collagen supplement
- Where
- 2 sites in China
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Guangdong HuaPeptides Biotechnology Co., Ltd.
Facial Skin Laxity
Clinical Study on the Application of a Non-Invasive Micro-Focused Ultrasound With Visualization System for Skin Laxity (ULT-215)
To evaluate the effect of the Ulthera® system for facial laxity and sagging skin
- Trial name
- ULT-215 (NCT03545412)
- Testing
- Microfocused ultrasound with visualization
- Volunteers
- 25 people
- Sponsor
- Ulthera, Inc
Wrinkle, Lax Skin
A Prospective Controlled Study to Evaluate the Safety and Effectiveness of Thermage® FLX Radiofrequency Treatment
A prospective, 180-day, randomized, multicenter, independent blinded evaluators, controlled study of treatment with the Thermage FLX System
- Conditions
- Wrinkle, Lax Skin, Lines Skin
- Trial name
- NCT07187297
- Testing
- Thermage FLX
- Where
- 7 sites in United States
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Bausch Health Americas, Inc.
Skin Depressions, Skin Elasticity
A Study to Evaluate the Effect of Juvederm Volift With Lidocaine on Aging Hands in Participants Age 35 and Older
This study will evaluate the effect of Juvederm Volift with Lidocaine, an injectable gel implant, to treat aging hands of participants 35 and older.
- Conditions
- Skin Depressions, Skin Elasticity, Skin Laxity
- Trial name
- NCT04390581
- Testing
- Juvéderm® VOLIFT with Lidocaine
- Where
- France
- Volunteers
- 75 people
- Sponsor
- Allergan
Muscle Tone, Muscle Strength
Pure Impact Treatment to Strengthen and Tone Abdomen, Quadriceps and Glutes Muscles
Open-label, non-randomized, prospective, single-center, self-controlled clinical study.
- Trial name
- NCT07094971
- Testing
- Pure Impact
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Sofwave Medical LTD
Facial Aging, Facial Skin Laxity
Safety and Efficacy Evaluation of the Xerf Device for Aesthetic Treatments
The goal of this clinical study is to evaluate the safety and clinical effectiveness of the XERF noninvasive dual-frequency monopolar radiofrequency device for aesthetic improvement of facial aging, including fine lines and…
- Conditions
- Facial Aging, Facial Skin Laxity, Submental and Neck Skin Laxity
- Trial name
- NCT07585591
- Testing
- Noninvasive dual-frequency monopolar radiofrequency
- Where
- 4 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- CynosureLutronic
Wrinkles
Safety and Efficacy Evaluation of Ultherapy™ System in Aging Hand
Enrolled subjects will receive Ultherapy™ System treatment on the back of their both hands. Follow-up visits will occur at 90 days post-treatment. Study photos will be obtained pre-treatment and at 90 days post-treatment
- Trial name
- NCT02364440
- Testing
- Ultherapy™ System
- Where
- South Korea
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Laxity; Skin
Pivotal Study to Evaluate the Safety and Efficacy of a Micro-coring Device Treating Moderate to Severe Facial Wrinkles
Study evaluating the safety and efficacy of a micro-coring device for the treatment of moderate to severe cheek wrinkles.
- Trial name
- NCT03573271
- Testing
- MCD
- Where
- 5 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cytrellis Biosystems, Inc.
Skin Laxity
Combined Focused Ultrasound and Calcium Hydroxylapatitie Filler for Skin Laxity and Volume Restoration
Non-invasive treatment options such as focused ultrasound has been used with success for the treatment of skin laxity in various parts of the body including the face, neck, décolletage, arms, buttocks, thighs, and legs.
- Trial name
- NCT04176068
- Testing
- calcium hydroxylapatite (Radiesse) and IFUS (Ulthera)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Cellulite
Treatment for Improvement of Cellulite Appearance Using Form Applicator
Open-label, non-randomized, prospective, multi-center, self-controlled clinical study with masked evaluation.
- Trial name
- NCT05882721
- Testing
- Sofwave
- Where
- 5 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sofwave Medical LTD
Skin Laxity, Lipodystrophy
CONFORM: Rotational Fractional Resection for Submental Contouring
This study will evaluate the safety and efficacy of rotational fractional resection (RFR) to improve neck contouring. RFR is used to remove loose skin and fat.
- Trial name
- NCT03407313
- Testing
- Rotational fractional resection (1.5mm diameter device)
- Where
- 6 sites in United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Recros Medica, Inc.
Wrinkle, Fine Lines
Feasibility Study to Collect and Assess Safety Data for a Radiofrequency Microneedling Device for Electrocoagulation and Hemostasis of Soft Tissues for Dermatologic Conditions
The goal of the Potenza device used in this study is to collect clinical data for dermatologic conditions in which electrocoagulation and hemostasis is a viable mechanism for means of improvement.
- Conditions
- Wrinkle, Fine Lines, Crepey Skin, Acne Scars
- Trial name
- NCT05987319
- Testing
- RadioFrequency Microneedling Device
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Cynosure, Inc.
Skin Laxity
SofWave Treatment to Lift Lax Tissue in the Submental and Neck Zones and to Lift the Eyebrow
Open-label, non-randomized, prospective, multi-center, self-controlled clinical study with masked evaluation.
- Trial name
- NCT04969380
- Testing
- Sofwave
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sofwave Medical LTD
Hypermobile EDS (hEDS), Hypermobile Ehlers-Danlos Syndrome
Hamstring Strengthening in Hypermobile Conditions
The goal of this clinical trial is to determine how strengthening the hamstring muscles affects the knee joint in people living with hypermobility spectrum disorders (HSD) and hypermobile Ehlers-Danlos syndrome (hEDS).
- Conditions
- Hypermobile EDS (hEDS), Hypermobile Ehlers-Danlos Syndrome, Hypermobile Spectrum Disorder, Hypermobility Type Ehlers-Danlos Syndrome
- Trial name
- NCT07626957
- Testing
- Progressive resistance exercise with an emphasis on eccentric hamstring loading.
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Calgary
Dermatochalasis of Eyelid, Ptosis, Eyelid
Brimonidine for Intraoperative Hemostasis
The purpose of this study is to observe and report the effects of topical ophthalmic brimonidine in oculofacial plastic surgery.
- Conditions
- Dermatochalasis of Eyelid, Ptosis, Eyelid, Ectropion, Entropion
- Trial name
- NCT05480098
- Testing
- Brimonidine Topical
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Louisville
Skin Aging
Randomized Trial of Combination Treatment With Sofwave and Sculptra
Evaluation of treatment on the upper arm with Sculptra and Sofwave on the same day versus Sofwave followed by Sculptra 1 month later.
- Trial name
- NCT07342452
- Testing
- Sofwave, Sculptra
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Face Rejuvenation, Neck Rejuvenation
Laser Treatment for Facial and Neck Rejuvenation
To assess the efficacy, safety, and patient satisfaction associated with the treatment of the face and neck with the 2,910nm mid-infrared UltraClear Laser System using both superficial epidermal ablation and deep ablative and…
- Trial name
- NCT05808842
- Testing
- CeraVe, CeraVe and Calecim
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Goldman, Butterwick, Fitzpatrick and Groff
Skin Laxity
Combination of Ultrasound Treatment and Neck Liposuction for Skin Tightening
The purpose of this study is to find out the effectiveness of ultrasound treatment and liposuction combined on skin tightening around the neck.
- Trial name
- NCT01735929
- Testing
- Neck Liposuction and Ultrasound Treatment
- Volunteers
- healthy volunteers welcome
- Sponsor
- Northwestern University