Clinical trials: Laxity; Skin
Wrinkle, Fine Lines
Feasibility Study to Collect and Assess Safety Data for a Radiofrequency Microneedling Device for Electrocoagulation and Hemostasis of Soft Tissues for Dermatologic Conditions
The goal of the Potenza device used in this study is to collect clinical data for dermatologic conditions in which electrocoagulation and hemostasis is a viable mechanism for means of improvement.
- Conditions
- Wrinkle, Fine Lines, Crepey Skin, Acne Scars
- Trial name
- NCT05987319
- Testing
- RadioFrequency Microneedling Device
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Cynosure, Inc.
Skin Laxity, Facial Aging
RESTRUCTURING THE MANDIBULAR ANGLE IN FACIAL AGING: A NOVEL TECNIQUE USING POLY-L-LACTIC ACID
Skin laxity is a common complaint among patients seeking aesthetic dermatological interventions, affecting the facial contour, especially in the mandibular angle, due to bone aging and the loss of tissue support in the lower…
- Trial name
- NCT06948045
- Testing
- PLLA application to the mandibular angle
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Doris Hexsel
Wrinkles and Rhytides
Treatment of Aging Signs of the Skin With Bipolar Radiofrequency
This is a retrospective data collection from patients treated with the bipolar radiofrequency applicator (Coaxipolar) of the Accent devices.
- Trial name
- NCT07739212
- Where
- Kosovo
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Alma Mater Europaea College of Medical Sciences "Rezonanca"
Skin Laxity
Combination of Ultrasound Treatment and Neck Liposuction for Skin Tightening
The purpose of this study is to find out the effectiveness of ultrasound treatment and liposuction combined on skin tightening around the neck.
- Trial name
- NCT01735929
- Testing
- Neck Liposuction and Ultrasound Treatment
- Volunteers
- healthy volunteers welcome
- Sponsor
- Northwestern University
Skin Laxity, Skin Aging
Cucurbita Pepo Flowers Extract to Promote Skin Health
The aim of this cosmetic clinical trial is to learn if an extract of Cucurbita pepo flower (CpLfe) works to enhance skin health and resilience in adult women with photo-damage.
- Conditions
- Skin Laxity, Skin Aging, Skin Wrinkling
- Trial name
- EACpLfe22S01 (NCT06674005)
- Testing
- Cucurbita pepo L. Flowers Extract
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ritamaria Di Lorenzo
Adipose Tissue
Evaluation of CoolSculpt Combining Venus Legacy Technology for Enhanced Results in Fat Reduction & Laxity of the Flanks
The purpose of this study is to evaluate the effect on the subject outcome using the combination of the Zeltiq Cryolipolysis device and the Venus Concept multipolar radiofrequency device with varipulse technology for the enhanced…
- Trial name
- NCT02569112
- Testing
- multipolar RF, varipulse, cryolipolysis
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Venus Concept
Dermatochalasis of Upper Eyelid, Blepharoplasty
Perioperative Haemostasis, Procedure-Related Pain After Physiological or Pharmacological Modifications of Local Anaesthesia Around the Eyes
The goal of this clinical trial is to determine whether buffering, warming, or addition of hyaluronidase or tranexamic acid to lignocaine during eyelid injection of local anaesthesia reduce injection pain and procedure-related…
- Trial name
- P4LE (NCT07734740)
- Testing
- Sodium Bicarbonate (NaHCO3), Warmed lignocaine, Hyaluronidase Injection
- Where
- 3 sites in Hong Kong
- Volunteers
- 80 people
- Sponsor
- Prince of Wales Hospital, Shatin, Hong Kong
Wrinkle
BTL-785F Device for Non-invasive Reduction of Wrinkles
This study will evaluate the clinical safety and the performance of the BTL-785F system equipped with the BTL-785-7 applicator for non-invasive treatment of facial wrinkles.
- Trial name
- NCT05519124
- Testing
- BTL-785-7
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- BTL Industries Ltd.
Skin Laxity
An Evaluation of the Erchonia Laser As a Non-Invasive Treatment to Improve the Appearance of Skin Laxity
The purpose of this clinical study is to determine the effectiveness of the Erchonia® GVS in improving the appearance of skin laxity on the abdominal region.
- Trial name
- NCT06941610
- Testing
- Erchonia GVS Laser
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Erchonia Corporation
Dermatochalasis, Dermatochalasis of Eyelid
Comparison of Two Different Concentrations of Local Anesthetic in Patient Reported Pain in Oculoplastic Surgery
The goal of this clinical trial is to compare pain scores in people undergoing upper eyelid surgery. The main questions it aims to answer are: Is one concentration of local anesthetic (also called numbing or freezing injection)…
- Conditions
- Dermatochalasis, Dermatochalasis of Eyelid, Dermatochalasis of Both Upper Eyelids, Dermatochalasis of Both Eyes
- Trial name
- NCT06121141
- Testing
- Full strength lidocaine with epinephrine, Dilute lidocaine with epinephrine
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Timothy Ekhlassi
Volume Deficiency in the Mid-Face, Skin Laxity
A Study to Characterize Human Skin Changes From Biostimulator Treatments Via Non-invasive Imaging
Adult subjects with moderate-to-severe cheek wrinkles will be treated with Sculptra for correction of fine lines and wrinkles in the cheek area.
- Conditions
- Volume Deficiency in the Mid-Face, Skin Laxity, Photo-aged Skin
- Trial name
- NCT07399028
- Testing
- Sculptra®
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Galderma R&D
Skin Aging, Wrinkles
Poly-L-lactic Acid (PLLA) Injection for Neck Skin Laxity: A Pilot Study
Skin aging of the neck commonly leads to wrinkles and skin laxity due to the gradual loss of collagen and structural support in the skin.
- Trial name
- NCT07689344
- Testing
- Poly-L-Lactic Acid (Sculptra) injection
- Where
- Thailand
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Institute of Dermatology, Thailand
Facial Skin Laxity
VISION Study: Visualization-Guided SMAS Treatment to Optimize Nonsurgical Lifting
The VISION study is a prospective, randomized, single-center, split-face Phase IV clinical trial evaluating whether customized multi-depth microfocused ultrasound with visualization (Ultherapy PRIME) targeting the…
- Trial name
- NCT07890987
- Testing
- Microfocused Ultrasound with Visualization (MFU-V), multi Microfocused Ultrasound with Visualization (MFU-V)
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ocean Clinic
Tightening of Skin Laxity
Application of the Apsara Thermal Wand System
The purpose of this feasibility study is to gain an initial assessment of the acute safety and performance of the Apsara Thermal Wand System in human facial tissue.
- Trial name
- NCT00662389
- Testing
- Apsara Thermal Wand System
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Apsara Medical Corporation
MACS Syndrome
MACS and Healthy Volunteers Bone Study
Adrenal adenoma is detected in 5-7% of adults and demonstrates mild autonomous cortisol secretion (MACS, dexamethasone suppression test >1.8 mcg/dl) in 50% of individuals with adenoma.
- Trial name
- NCT04343560
- Where
- United States
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Skin Aging
Randomized Trial of Combination Treatment With Sofwave and Sculptra
Evaluation of treatment on the upper arm with Sculptra and Sofwave on the same day versus Sofwave followed by Sculptra 1 month later.
- Trial name
- NCT07342452
- Testing
- Sofwave, Sculptra
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Skin Laxity of Abdomen, Thighs, Chest, Back, and Neck
Suture Granuloma in Body Contouring Surgery
The purpose of this study is to evaluate the effect of different suture material on the incidence of suture granuloma.
- Trial name
- NCT00223132
- Testing
- Absorbable sutures
- Where
- United States
- Sponsor
- Medtronic - MITG
Skin Laxity
Radiofrequency and Pulsed Electromagnetic Field Treatment of Skin Laxity of the Mon Pubis, Labia and Vaginal Introitus
The study will confirm that the Freeze Diamond polar applicator is safe for treating the Mons pubis and Labia, and will result in improvement in general skin appearance including an improvement in skin irregularities and skin…
- Trial name
- NCT02770287
- Testing
- Venus Freeze Diamond Polar
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Venus Concept
Skin Laxity
Injectable Poly-L-Lactic Acid for Volumization and Adipogenesis of the Hip Dell
To assess the safety, efficacy and subject satisfaction associated with volumization of the hip dell with injectable poly-L-lactic acid (PLLA), or Sculptra® Aesthetic (Galderma Laboratories, Fort Worth, TX).
- Trial name
- NCT05269654
- Testing
- injectable poly-L-lactic acid, Normal Saline
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Goldman, Butterwick, Fitzpatrick and Groff
Skin Depressions, Skin Elasticity
A Study to Evaluate the Effect of Juvederm Volift With Lidocaine on Aging Hands in Participants Age 35 and Older
This study will evaluate the effect of Juvederm Volift with Lidocaine, an injectable gel implant, to treat aging hands of participants 35 and older.
- Conditions
- Skin Depressions, Skin Elasticity, Skin Laxity
- Trial name
- NCT04390581
- Testing
- Juvéderm® VOLIFT with Lidocaine
- Where
- France
- Volunteers
- 75 people
- Sponsor
- Allergan