Clinical trials: Lead Exposure
Lead Poisoning, Environmental Exposure
A Study to Assess the Efficacy of Public Health Campaigns in Reducing Lead Exposure
This clinical trial aims to evaluate the effectiveness of targeted public health campaigns in reducing lead exposure among adults living in urban communities with known environmental lead hazards.
- Trial name
- NCT07632937
- Testing
- Intensive Public Health Campaign, Standard Information Dissemination
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- International Health Strategies LLC
Lead Poisoning, Neurotoxicity
Effects of Lead Exposure on Ferroptosis Pathway
The aim of this study was to investigate the effects of chronic lead exposure on iron metabolism and the Nrf2-dependent ferroptosis pathway in lead acid battery factory workers
- Trial name
- NCT05950386
- Testing
- Lead exposure
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Northern Jiangsu People's Hospital
Lead Exposure
Bone-Lead Level Associations With Brain and Mental Health
The goal of this study is to assess cumulative lead exposure among treatment-seeking patients in the MUSC hospital system receiving experimental transcranial magnetic stimulation (TMS), transcranial direct-current stimulation…
- Trial name
- NCT05887934
- Testing
- X-Ray Fluorescence Analyzer
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Early-phase Safety and PK Study of a Vaginal Gel
FIH Lead-in Study of YASO GEL Followed by a Phase 1 Randomized, Double-blind Study to Assess Safety and Pharmacokinetics of YASO GEL
The goal of this clinical trial is to assess the safety and pharmacokinetics of YASO GEL in healthy adult participants. This is a first-in-human study designed to understand how the gel is absorbed and distributed in plasma and…
- Trial name
- PPCM-01 (NCT07281404)
- Testing
- YASO GEL
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Yaso Therapeutics Corporation
Lead Poisoning
Social Network Based Intervention to Reduce Lead Exposure Among Native American Children
The purpose of this study is to examine whether adding an inter-generational component to an existing social network-based lay health advisor intervention increases its effectiveness in mobilizing a Native American community to…
- Trial name
- NCT00011661
- Testing
- Education on behaviors to reduce lead exposure
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Iron Deficiency, Lead Poisoning
Iron Fortification Trail Using NaFeEDTA in Iron Deficient Lead-exposed Children
In a cross-sectional study allotted by the ethical committee of the ETH Zurich, we are investigating the extent of anemia, iron deficiency and lead intoxication in young children.
- Trial name
- NCT01573013
- Testing
- iron fortified biscuits
- Where
- Switzerland
- Volunteers
- 457 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Lead Toxicity
Iron Supplementation of Lead-exposed Infants
The purpose of this study is to compare the efficacy of iron (12.5 mg as ferrous sulfate) and placebo given for 6 months in preventing the elevation of blood lead concentration in children 6-9 months of age.
- Trial name
- NCT00374790
- Testing
- Ferrous sulfate
- Where
- Uruguay
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cornell University
Lead Poisoning
Exposure, Dose, Body Burden and Health Effects of Lead
This is a study of the effects that lead has on the health of the central nervous system (for example, memory), peripheral nervous system (for example, sensation and strength in the hands and fingers), kidneys, blood pressure…
- Trial name
- NCT00013819
- Volunteers
- 944 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Radiation Exposure to Operator, Endovascular Aortic Repair
Exoskeleton vs. Standard Lead Apron in EVAR Procedures
The goal of this clinical trial is to learn whether an exoskeleton-supported radiation protection system can reduce radiation exposure and musculoskeletal strain in vascular surgeons during endovascular aortic repair procedures…
- Conditions
- Radiation Exposure to Operator, Endovascular Aortic Repair, Musculoskeletal Strain, Occupational Radiation Exposure
- Trial name
- PROTECT-EVAR (NCT07528144)
- Testing
- Exoskeleton-supported radiation protection system, Standard lead apron
- Where
- Poland
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Samodzielny Publiczny Szpital Kliniczny nr 2 PUM
Health Literacy, Language
English as a Second Language Health Literacy Program
This research is using a Community-Based Participatory Action Research (CBPAR) approach to design, implement, and evaluate English as a Second Language health literacy classes for Hispanic adults to reduce lead exposure.
- Trial name
- NCT04125680
- Testing
- ESL Health Literacy Classes
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Lead Poisoning, Lead Poison Children
Evaluation of the Impact of a Personal and Domestic Hygiene Intervention on Lead Exposure in a Community Close to a Mine Dump
The study evaluates the impact of a personal and domestic hygiene intervention on exposure to lead in a community close to a mine dump.
- Trial name
- NCT05265572
- Testing
- Domestic Hygiene and household hygiene Intervention
- Where
- South Africa
- Volunteers
- 576 people, healthy volunteers welcome
- Sponsor
- University of Johannesburg
Lead Poisoning
Lead Mobilization & Bone Turnover in Pregnancy/Lactation
We are examining the role of maternal bone lead turnover during pregnancy and lactation as a potential source of lead exposure for the fetus and the infant (via breast milk).
- Trial name
- NCT00011726
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Attention Deficit Disorder
Attention Deficit Disorder and Exposure to Lead
We are examining the past exposure to lead in 250 well characterized children with ADHD, and a suitable group of controls. Our measure of past exposure is bone lead levels obtained by XRay fluorescence spectroscopy, a relatively…
- Trial name
- NCT00014898
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Multiple Sclerosis
Lead Exposure and Multiple Sclerosis
1. To evaluate the effect of lead level on the pathogenesis of multiple sclerosis 2. Measure lead in blood sample of study groups 3. Estimate the expression level of DNA methyltransferase. 4.
- Trial name
- NCT07423312
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Assiut University
Lead Poisoning
Early Exposure to Lead and Adolescent Development
This prospective cohort study examines the role of prenatal and early postnatal lead exposure on the neuropsychological status and social adjustment of adolescents enrolled in the Cincinnati Lead Study.
- Trial name
- NCT00011674
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Lead Exposure
G-PUR® for Reduced Lead Bioavailability
This is a prospective, randomized, placebo-controlled, double blind, parallel-arm study in a two-staged approach that will assess the effect of two different doses of G-PUR® on enteral lead absorption in healthy adults using a…
- Trial name
- NCT04138693
- Testing
- G-PUR® 2x 2.0 g oral suspension, G-PUR® 1x 2.0 g oral suspension
- Where
- Austria
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Glock Health, Science and Research GmbH
Osteoporosis
Lead Exposure, Genetics, and Osteoporosis Epidemiology
This study's primary objective is to assess the effects of environmental lead exposures and genetic risk factors on the development of osteoporosis in middle-aged women.
- Trial name
- NCT00013637
- Where
- United States
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Lead, Toxicology
Potential Lead Exposure Through Eating Self-harvested Wild Game
This is a clinical research protocol to determine the feasibility of assessing lead levels in hunters who use lead projectiles. This study will determine if it is possible to perform an interventional double-blind…
- Trial name
- NCT02775890
- Testing
- Eating wild game shot with lead bullets
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Nelson Marlborough Institute of Technology
Lead Poisoning
Bone Lead Levels and College Achievement Scores
This project studies the relationship between lead exposure and academic achievement in college students. Most studies of the neurobehavioral effects of lead have focused on performances at the low end of the distribution.
- Trial name
- NCT00014885
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Lead Poisoning
Effects of Iron and/or Zinc Supplementation in Mexican School Children Exposed to Lead
Lead is negatively linked to nutritional status, behavior and cognition in children. Despite extensive knowledge of its toxicity and efforts to reduce exposure, lead continues to be a problem in developed and developing…
- Trial name
- NCT02346188
- Testing
- Ferrous fumarate, Zinc oxide
- Where
- United States
- Volunteers
- 602 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health