Clinical trials: Lead Poisoning
Diagnostic Errors
Reducing Diagnostic Errors in Primary Care Pediatrics (Project RedDE)
The proposal will focus on 3 specific, high-risk, pediatric ambulatory diagnostic errors each representing a unique dimension of diagnostic assessment: evaluation of symptoms, evaluation of signs and follow-up of diagnostic…
- Trial name
- NCT02798354
- Testing
- Quality Improvement Collaborative
- Where
- United States
- Volunteers
- 13,853 people
- Sponsor
- Montefiore Medical Center
Lead Poisoning
The Combined Effect of 2,3-Dimercaptosuccinic Acid and Multi-Nutrients on Children in Lead Poisoning
Lead poisoning remains a common disease among children despite successful public health efforts that reduced its prevalence.Our study was designed to test the hypothesis that lead-poisoning children (BLLs:100-440µg/L) who were…
- Trial name
- NCT00374894
- Testing
- 2,3-dimercaptosuccinic acid
- Where
- China
- Volunteers
- 500 people
- Sponsor
- China Medical University, China
Lead Poisoning
Plan for Testing Fingerstick Bloods on Magellan Systems
This study is to supplement our internal data that demonstrates the continued performance of capillary blood samples on Magellan's lead testing systems: LeadCare II, LeadCare Ultra (which have been cleared previously by FDA), and…
- Trial name
- NCT03256383
- Testing
- Lead testing
- Where
- 3 sites in United States
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Magellan Diagnostics
Iron Deficiency, Lead Poisoning
Iron Fortification Trail Using NaFeEDTA in Iron Deficient Lead-exposed Children
In a cross-sectional study allotted by the ethical committee of the ETH Zurich, we are investigating the extent of anemia, iron deficiency and lead intoxication in young children.
- Trial name
- NCT01573013
- Testing
- iron fortified biscuits
- Where
- Switzerland
- Volunteers
- 457 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Lead Poisoning, Vitamin D Deficiency
Penicillamine Chelation for Children With Lead Poisoning
Childhood Lead Poisoning is a widespread disease that has few effective treatments. The specific aims of this proposed clinical trial are threefold: To determine whether a six-week course of a newly formulated d-penicillamine…
- Trial name
- NCT00552630
- Testing
- d-penicillamine
- Where
- United States
- Sponsor
- FDA Office of Orphan Products Development
Lead Poisoning
RECLEAN Pilot Study
This is an exposure assessment pilot study tailored for families of construction workers living with a child. The investigators will compare home dust metal levels and resident's blood metal levels before and after an educational…
- Trial name
- RECLEAN (NCT04498845)
- Testing
- In-home assessment plan, Family educational session, Worker take home prevention training
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Boston University
Lead Poisoning, Lead Poison Children
Evaluation of the Impact of a Personal and Domestic Hygiene Intervention on Lead Exposure in a Community Close to a Mine Dump
The study evaluates the impact of a personal and domestic hygiene intervention on exposure to lead in a community close to a mine dump.
- Trial name
- NCT05265572
- Testing
- Domestic Hygiene and household hygiene Intervention
- Where
- South Africa
- Volunteers
- 576 people, healthy volunteers welcome
- Sponsor
- University of Johannesburg
Lead Poisoning
Exposure, Dose, Body Burden and Health Effects of Lead
This is a study of the effects that lead has on the health of the central nervous system (for example, memory), peripheral nervous system (for example, sensation and strength in the hands and fingers), kidneys, blood pressure…
- Trial name
- NCT00013819
- Volunteers
- 944 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Alpha-Gal Syndrome
The α-gal Syndrome - Investigating Immune Reactions to Tick Bites
Tick bites can transmit pathogens, but they can also induce a food allergy to mammalian meat. The goal of this clinical trial is to follow immune response and antibody build-up in individuals bitten by a tick.
- Trial name
- ImmunoGal (NCT07177729)
- Where
- 2 sites in Luxembourg
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Luxembourg Institute of Health
Male Infertility, Testicular Diseases
Effect of Environmental Exposures on the Egg Fertilizing Ability of Human Sperm
Our data indicate that environmental exposure to the heavy metal lead are more widespread than currently appreciated and that such exposures are associated with the production of human male subfertility.
- Conditions
- Male Infertility, Testicular Diseases, Urologic and Male Genital Diseases, Lead Poisoning
- Trial name
- NCT00012480
- Where
- 3 sites in United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Lead Poisoning, Neurotoxicity
Effects of Lead Exposure on Ferroptosis Pathway
The aim of this study was to investigate the effects of chronic lead exposure on iron metabolism and the Nrf2-dependent ferroptosis pathway in lead acid battery factory workers
- Trial name
- NCT05950386
- Testing
- Lead exposure
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Northern Jiangsu People's Hospital
Lead Poisoning
Early Exposure to Lead and Adolescent Development
This prospective cohort study examines the role of prenatal and early postnatal lead exposure on the neuropsychological status and social adjustment of adolescents enrolled in the Cincinnati Lead Study.
- Trial name
- NCT00011674
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Poisoning, Lead
Identifying Residential Hazards Using Home Test Kits
The purpose of this project is to help families and communities identify and reduce health risks from lead, pesticides and, ultimately, other environmental hazards.
- Trial name
- NCT00285532
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Lead Poisoning
Homeopathic Preparation Plumbum Metallicum for Lead Poisoning
Saturnism, or lead poisoning, is defined by clinical symptoms (affecting primarily the nervous, hematopoietic, gastrointestinal, cardiovascular, musculoskeletal, renal and reproductive systems) compatible with exposure, in the…
- Trial name
- NCT00931905
- Testing
- Homeopathic medication Plumbum metallicum, Hydroalcoholic solution
- Where
- Brazil
- Volunteers
- 113 people
- Sponsor
- Federal University of São Paulo
Lead Poisoning
Does Lead Burden Alter Neuropsychological Development?
Inner city children are at an increased risk for lead overburden. This in turn affects cognitive functioning. However, the underlying neuropsychological effects of lead overburden and its age-specific effects have not been well…
- Trial name
- NCT00000104
- Testing
- ERP measures of attention and memory
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Center for Research Resources (NCRR)
Anemia, Malnutrition
Environmental Exposure to Lead and Its Health Effects on Patients With Maintenance Hemodialysis
One thousand patients with LHD who have no history of exposure to lead will be observed for 18 months. Blood lead level(BLL), biochemical data, hemoglobin, albumin, Cr, high sensitivity C-reactive protein (HsCRP), and blood cell…
- Conditions
- Anemia, Malnutrition, Inflammation, Lead Poisoning
- Trial name
- NCT00926406
- Testing
- lead chelation therapy
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Chang Gung Memorial Hospital
Lead Exposure
Treatment of Lead-Exposed Children Trial
The Treatment of Lead-Exposed Children (TLC) clinical trial compared the effect of lead chelation with succimer to placebo therapy.
- Trial name
- NCT00342849
- Testing
- Succimer
- Where
- 4 sites in United States
- Volunteers
- 780 people
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Vitamin D Deficiency, Iodine Deficiency
Vitamin D, Iodine, and Lead Levels in Haitian Infants and Children.
Vitamin D deficiency is common worldwide, including in infants and children, and rickets remains a public health concern in many developing countries.
- Conditions
- Vitamin D Deficiency, Iodine Deficiency, Hypothyroidism, Rickets
- Trial name
- Haiti (NCT02301520)
- Where
- 2 sites in Haiti
- Volunteers
- 299 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Mercury Poisoning, Lead Poisoning
Environmental Contaminants and Infant Development
This study is designed to examine the effects of prenatal exposure to environmental contaminants on cognitive and behavioral development and physical growth in two groups of Inuit infants-one in Northern Quebec; the other in…
- Trial name
- NCT00013858
- Where
- Canada
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Lead Poisoning
Lead Mobilization & Bone Turnover in Pregnancy/Lactation
We are examining the role of maternal bone lead turnover during pregnancy and lactation as a potential source of lead exposure for the fetus and the infant (via breast milk).
- Trial name
- NCT00011726
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)