Clinical trials: Lean Body Mass
Obesity
Effect of Conjugated Linoleic Acid Supplement on Body Composition
The purpose of this clinical trial is to examine the effects of a low and high dose of conjugated linoleic acid supplement on body composition in obese humans.
- Trial name
- NCT00347373
- Testing
- Tonalin Conjugated linoleic acid (dietary supplement)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of North Carolina
Weight Gain
Role of Peanuts in Healthy Weight Gain in Athletic Individuals
Many athletes and military personnel desire weight gain primarily as lean mass to improve performance and effectiveness in military/sport endeavors.
- Trial name
- mGAINS (NCT05426109)
- Testing
- Peanut snacks, No peanut-containing snacks
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Virginia Polytechnic Institute and State University
Body Composition Changes
Magnesium Supplementation on Body Composition
The goal of this interventional clinical trial is to learn if the supplementation of magnesium can affect body composition in physically active individuals between the ages of 18 and 30.
- Trial name
- NCT06703099
- Testing
- Magnesium Supplementation
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Nova Southeastern University
Healthy Volunteers
Effect of Two Pilates-based Mat Exercise Programs on the Isometric Strength of Core Muscles in Healthy Men
Based on the current evidence, it is known that Pilates is an exercise technique that has been used mainly by women in sport, fitness and rehabilitation. Most research has been developed with women.
- Trial name
- NCT03830112
- Testing
- Pilates exercise with Theraband, Pilates exercise
- Where
- Colombia
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Universidad de Antioquia
ER+ and AR+ Breast Cancer
Add-on Study for Protocol G200802 (NCT02463032): Effect of GTx-024 on Maximal Neuromuscular Function and Lean Body Mass
This is a multiple site, proof of concept feasibility study to describe the effect of GTx-024 9 or 18 mg on physical function in female subjects, from protocol G200802, with ER+/AR+ breast cancer.
- Trial name
- NCT02746328
- Testing
- GTx-024 9 or 18 mg
- Where
- United States
- Sponsor
- GTx
Muscle Mass
Strength Training Response of Muscle in GLP-1 Users
GLP-1 medication is being prescribed for weight loss. However, GLP-1 medication may adversely affect muscle mass and muscle function.
- Trial name
- STRONG-GLP (NCT07104539)
- Testing
- Strength Training, Wait first, then strength training
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Virginia Polytechnic Institute and State University
Spinal Cord Injury, Spinal Cord Injuries
Locomotor Training With Testosterone to Promote Bone and Muscle Health After Spinal Cord Injury
This pilot study will determine the feasibility of implementing a combinatory rehabilitation strategy involving testosterone replacement therapy (TRT) with locomotor training (LT; walking on a treadmill with assistance and…
- Conditions
- Spinal Cord Injury, Spinal Cord Injuries, Trauma, Nervous System, Wounds and Injury
- Trial name
- NCT04460872
- Testing
- Testosterone Enanthate, Locomotor Training
- Where
- 2 sites in United States
- Volunteers
- 21 people
- Sponsor
- North Florida Foundation for Research and Education
Lean Body Mass
Does Muscle Mass At Intensive Care Unit Admission Determine Mortality: the Memo Study
This retrospective monocentric study aims to investigate whether a low muscle mass at ICU admission and its loss over the ICU stay predicts mortality, and in what proportion we can counteract it by nutritional support.
- Trial name
- MEMO (NCT05834894)
- Testing
- exposure(s) of interest : intensive care unit
- Where
- Switzerland
- Volunteers
- 4,000 people
- Sponsor
- University Hospital, Geneva
Hemophilia
Weight-based Dosing in Hemophilia A
Hemophilia A is an inherited (genetic) disease where a protein, factor VIII (FVIII), which promotes blood clotting is missing or does not work properly. Individuals with hemophilia A are at risk for bleeding.
- Trial name
- NCT02586012
- Testing
- rFVIII
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Craig Seaman
Newly Diagnosed Multiple Myeloma
Multiple Myeloma and Exercise
This study will establich the feasibility of weight lifting exercise among patients with multiple myeloma, determine if weight lifting exercise increases lean body mass among patients with multiple myeloma and obtain further…
- Trial name
- NCT01809717
- Testing
- Weight Lifting Exercises
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Prematurity; Extreme, Feeding Disorder Neonatal
Early Protein Supplementation in Extremely Preterm Infants Fed Human Milk
The central hypothesis of this clinical trial is that, in extremely preterm infants, protein-enriched human milk diets compared to usual human milk diets during the first 2 weeks after birth increase fat-free mass (FFM)-for-age Z…
- Conditions
- Prematurity; Extreme, Feeding Disorder Neonatal, Breast Milk Expression, Growth Failure
- Trial name
- NCT04325308
- Testing
- Protein-enriched human milk diet, Usual human milk diet
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Alabama at Birmingham
Burns, Growth Hormone Treatment
Growth Hormone Therapy for Muscle Regeneration in Severely Burned Patients
The investigators have previously demonstrated that burn injury causes severe muscle wasting, weight and height retardation, and systemic protein catabolism in pediatric and adult burned patients.
- Trial name
- NCT03038594
- Testing
- Somatropin, 0.09% Saline Solution
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Energy Intake, Activities of Daily Living
Impact on Energy Intake by Implementing Recommended Food Texture Through Dietary Guidance
An intervention study on the effect of dietary guidance with focus on implementing recommended food texture, at the department of Eating and Swallowing difficulties, Region Midtjylland, Denmark.
- Conditions
- Energy Intake, Activities of Daily Living, Quality of Life, Protein Intake
- Trial name
- NCT04655547
- Testing
- Dietary guidance
- Where
- Denmark
- Volunteers
- 13 people
- Sponsor
- University of Aarhus
Cystic Fibrosis
Impact of a Coordinated Dietetic-adapted Physical Activity Program on the Percentage of Lean Body Mass in Adults With Cystic Fibrosis Treated With Elexacaftor-Tezacaftor-Ivacaftor: Multicentre Randomised Controlled Trial
Cystic fibrosis is an autosomal recessive inherited disease linked to various mutations in the gene coding for the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) protein, with respiratory and digestive disorders…
- Trial name
- DIAPASOM (NCT06457451)
- Testing
- DIAPASOM program
- Where
- 4 sites in France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Tours
Overweight, Obesity
"Improving Diet, Exercise And Lifestyle (IDEAL) for Women" Study
Diets all share the same principle: eat less energy than you need. This results in weight loss. However, the weight loss is usually a combination of a loss of body fat and muscle mass.
- Trial name
- NCT00710398
- Testing
- Exercise - Aerobic and Resistance, Dietary - Caloric Restriction
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- McMaster University
Obesity
Effects of Zinc Supplementation on Anthropometric Factors, Apelin and Inflammatory Markers in Obese Individuals
To study the effects of zinc supplement on anthropometric factors, Apelin and inflammatory markers in obese individuals, 50 obes person who referred to Diet and Nutrition clinic of Shahid Beheshti University of Medical Sciences…
- Trial name
- NCT02516475
- Testing
- zinc sulfate, corn starch
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Nutrition and Food Technology Institute
Sarcopenia, Post-operative Infections
Phase Angle, Lean Body Mass Index and Tissue Edema and Immediate Outcome of Cardiac Surgery Patients
In general, malnutrition in surgical patients is associated with a higher risk of postoperative infections, decreased immune response, more cardiac complications, prolonged mechanical ventilation , and a higher rate of…
- Conditions
- Sarcopenia, Post-operative Infections, Sepsis
- Trial name
- NCT03644030
- Where
- Greece
- Volunteers
- 179 people
- Sponsor
- Aristotle University Of Thessaloniki
Athlete, Relative Energy Deficiency in Sport
Preventing Athlete Under-fueling Through Nutrition.
The goal is to improve nutrition screening and support for Division III athletes. The study will use standard, low-risk nutrition screening methods, such as measuring height, weight, grip strength, and body composition, as well…
- Conditions
- Athlete, Relative Energy Deficiency in Sport, Low Energy Availability
- Trial name
- PERFORM (NCT07136038)
- Testing
- Low Energy Availability Screening and Nutrition Support
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
Obesity, Muscle Loss
A Study of the Effect of (S)-Pindolol Benzoate (ACM-001.1) on Lean Body Mass (LBM) in Obese Patents During (PROACT 1), and Post-semaglutide Therapy (PROACT 2)
Semaglutide is approved for weight management (weight loss and weight maintenance) in adult obese patients. Drug treatments like semaglutide that result in weight-loss can also decrease muscle mass.
- Trial name
- PROACT (NCT07101939)
- Testing
- (S)-pindolol benzoate, Semaglutide
- Where
- 7 sites in Serbia
- Volunteers
- 120 people
- Sponsor
- Actimed Therapeutics Ltd
Wounds, Lean Body Mass
Amino Acid Usage Patterns in Daily Practice
The present study aims to evaluate the patient profile including medical conditions who use a nutritional supplement along with a balanced and varied diet in Turkey.
- Trial name
- NCT02146612
- Testing
- Amino Acid Supplement Group
- Where
- 18 sites in Turkey (Türkiye)
- Volunteers
- 354 people
- Sponsor
- Abbott Nutrition