Clinical trials: Learning Development, active
Mild Cognitive Impairment
LifeBio Memory: Development of a Reminiscence Therapy Online Platform With Machine Learning to Increase Engagement
LifeBioMEMORY (LBM) is a reminiscence therapy (RT) mobile application that captures older adults' life stories in their own voices to promote social engagement and psychosocial well-being.
- Trial name
- LifeBio Memory (NCT07685067)
- Testing
- LifeBio Memory (LBM) digital reminiscence intervention
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- George Mason University
Down Syndrome
How Simplified Language Affects Comprehension and Learning in Young Children With Down Syndrome
The long-term study goal is to experimentally evaluate the components (and likely active ingredients) of early language interventions for young children with Down syndrome (DS).
- Trial name
- NCT06951516
- Testing
- Linguistic simplification
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Michigan State University
Nutrition Education, Enhanced Recovery After Surgery
Nutrition Education in Spine Surgery
The goal of this interventional study is to learn if having 15 minutes of surgery related nutrition education changes the food choices participants make during the time right before and after a spine surgery in participants who…
- Trial name
- NCT06719492
- Testing
- nutrition education
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- Jennifer Bowden
Movement Disorders, Neurorehabilitation
Towards Restoring Complex Movement After Paralysis: Algorithm Development With Healthy Participants
Participants will perform experiments with non-invasive activity recordings. The study will record from multiple non-invasive signal sources that reflect motor intent that may include: electroencephalography (EEG)…
- Conditions
- Movement Disorders, Neurorehabilitation, Non-invasive Activity Recording
- Trial name
- NCT07236892
- Testing
- Participants will perform experimental tasks while undergoing non-invasive activity recordings, which may include EEG, EMG, IMUs, fNIRS, eye gaze, or pupillometry.
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Autism, Sociocommunicative Challenges
Improving Autism Program Quality in Special Education Units: The Use of an APERS-based Model to Support Student Learning and Participation
This study assesses the effect of using the Autism Program Environment Rating Scale (APERS) as a tool for providing feedback, in-service training, and coaching to school staff in order to improve program quality in special…
- Trial name
- NCT07830160
- Testing
- APERS+
- Where
- Sweden
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Stockholm University
Prehospital Emergency Medical Services, Point-of-care Ultrasound
Ultrasound Applications for Emergency Medical Technicians in Taiwan
The goal of this prospective observational study is to develop and assess the core ultrasound applications for emergency medical technicians (EMTs) in Taiwan.
- Trial name
- NCT06950333
- Testing
- POCUS education curriculum
- Volunteers
- 200 people
- Sponsor
- National Taiwan University Hospital
Nasopharyngeal Cancinoma (NPC), Lymph Node Metastasis
A Deep Learning Model for Diagnosing Lymph Node Metastasis in Nasopharyngeal Carcinoma(NPC)
(I) AI Model for Diagnosing Lymph Node Metastasis We developed an AI model to help diagnose whether a single lymph node in nasopharyngeal cancer has spread. The model uses MRI images of the lymph node and the area around it.
- Trial name
- NPC (NCT06829147)
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Sun Yat-sen University
Autism Spectrum Disorder, Autism
Internet-delivered Cognitive-Behavioral Therapy for Adolescents With Autism and Anxiety
Anxiety is very common in autistic youth. Cognitive behavioral therapy (CBT) is the recommended treatment for both autistic and typically-developing (TD) youth with anxiety, yet most families cannot access CBT due to cost…
- Conditions
- Autism Spectrum Disorder, Autism, Anxiety, Anxiety Disorders
- Trial name
- LUNA-A (NCT06537128)
- Testing
- LUNA-Adolescent, Treatment as Usual
- Where
- United States
- Volunteers
- 139 people
- Sponsor
- Baylor College of Medicine
Endodontic Retreatment, Non-surgical Retreatment
Development and Validation of a Deep Learning Model to Predict Endodontic Retreatment Difficulty From Periapical Radiographs
The aim of this study is to develop and evaluate an artificial intelligence-based model capable of analyzing periapical radiographs of maxillary and mandibular molars to predict the difficulty level of non-surgical root canal…
- Conditions
- Endodontic Retreatment, Non-surgical Retreatment, Endodontics, AI (Artificial Intelligence)
- Trial name
- Ai Retreatment (NCT07611279)
- Testing
- Deep Learning Model to Predict Endodontic Retreatment Difficulty from Periapical Radiographs
- Volunteers
- 123 people
- Sponsor
- Cairo University
Clinical Education, Health Sciences
Clinical Education Environment Assessment Scale
This study aims to develop and evaluate a questionnaire that measures how health sciences students perceive the clinical environments in which they complete internships or clinical placements.
- Trial name
- NCT07707154
- Testing
- Observational assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 310 people, healthy volunteers welcome
- Sponsor
- Lokman Hekim University
Child Development, Child Behavioral Problems
LOVING (Learning About Our Behavior is Valuable for Increasing Nurturing Relationships and Healthy Growth) RCT
The LOVING study is a randomized controlled trial designed to determine whether adaptations to an internationally recognized parenting program that enhances sensitive caregiving likewise improves sensitive caregiving in Singapore…
- Conditions
- Child Development, Child Behavioral Problems, Parent Child Relationship
- Trial name
- LOVING (NCT07687524)
- Testing
- VIPP-SD-SingH, "Video-Feedback Intervention to Promote Positive Parenting and Sensitive Discipline Adapted for the Singapore Context with a Health Component", CARE-SD, "Caregiver Awareness of Relationships through E-learning for Sensitivity and Discipline", NeuroEducation for Parents
- Where
- 5 sites in Singapore
- Volunteers
- 624 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Adolescence Idiopathic Scoliosis
Machine Learning Prediction of Disease Progression in Adolescent Idiopathic Scoliosis
Background and Problem Overview Adolescent Idiopathic Scoliosis (AIS) is a progressive musculoskeletal disorder characterized by a three-dimensional deformation of the spine occurring during adolescence.
- Trial name
- NCT07556042
- Testing
- Core Stabilization Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Istanbul University
ARDS (Acute Respiratory Distress Syndrome), Respiratory Failure
Development and Prospective Validation of the AutoEIT Foundation Model for ARDS
Acute Respiratory Distress Syndrome (ARDS) is a highly heterogeneous condition, making precision mechanical ventilation challenging.
- Conditions
- ARDS (Acute Respiratory Distress Syndrome), Respiratory Failure, Mechanical Ventilation, Ventilator-induced Lung Injury (VILI)
- Trial name
- NCT07898319
- Testing
- AutoEIT Model Training, AutoEIT Blinded Validation
- Where
- China
- Volunteers
- 1,200 people
- Sponsor
- Ruijin Hospital
Hearing Impaired Children
Artificial Grammar Learning in Children Who Are Deaf or Hard-of-Hearing: Stimulus Length Effect
The goal of this basic experimental study involving humans (BESH) clinical trial is to examine how stimulus length affects grammar learning in children who are deaf or hard-of-hearing and who primarily use spoken language.
- Trial name
- NCT07782567
- Testing
- Short linguistic content, Long linguistic content
- Volunteers
- 30 people
- Sponsor
- University of Illinois Chicago
Suicide Prevention, Suicidal Ideation
Online Suicide Prevention and Intervention Training for Secondary School Counselors
The aim of this study is to develop and evaluate the effectiveness of the Online Suicide Prevention and Intervention Training Program (Çevrimiçi İntihar Önleme ve Müdahale Eğitim Programı - ÇİÖMEP) for school counselors working…
- Conditions
- Suicide Prevention, Suicidal Ideation, School Counseling
- Trial name
- NCT07432438
- Testing
- Online Suicide Prevention and Intervention Training Program (ÇİÖMEP)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Cancer-related Pain, Pain Assessment
Developing a Multimodal Cancer Pain Database to Support AI-Based Automatic Pain Assessment
The goal of this observational study is to collect short video and sound recordings of people with cancer to create a secure database that can be used in future research to develop an artificial intelligence (AI) tool for pain…
- Conditions
- Cancer-related Pain, Pain Assessment, Artificial Intelligence (AI), Oncology
- Trial name
- SENSAI-DBD (NCT07262632)
- Testing
- Audiovisual and questionnaire-based data collection (once), Audiovisual and questionnaire-based data collection (consecutive)
- Where
- Netherlands
- Volunteers
- 200 people
- Sponsor
- Dr. Mark Mulder
Normal Physiology
Development and Validation of Learning and Decision-Making Tasks
Background: Substance use disorders (SUD) can be considered disorders in the way people process incentives, learn, and make decisions.
- Trial name
- NCT05707806
- Testing
- MRI
- Where
- United States
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Multiple Myeloma
A Study to Learn About the Effects of the Combination of Elranatamab, Daratumumab and Lenalidomide Compared With Daratumumab, Bortezomib, Lenalidomide, and Dexamethasone in Patients With Newly Diagnosed Multiple Myeloma Who Are Not Candidates for Transplant
Elranatamab is a bispecific antibody: binding of elranatamab to CD3-expressing T-cells and BCMA-expressing multiple myeloma cells causes targeted T-cell-mediated cytotoxicity.
- Trial name
- MagnetisMM-6 (NCT05623020)
- Testing
- Elranatamab, Daratumumab, Lenalidomide
- Where
- 180 sites in United States, Argentina and 23 more
- Volunteers
- 1,060 people
- Sponsor
- Pfizer
Alzheimer Disease, Dementia
CONSTELLATIONS Living Lab: Improving the Care Transitions of Older Adults Living with Neurocognitive Disorders
The prevalence of major neurocognitive disorders (MNCDs), particularly Alzheimer's disease, among older adults is increasing. These individuals and their caregivers often face challenges due to inefficient and poorly coordinated…
- Conditions
- Alzheimer Disease, Dementia, Neurocognitive Decline
- Trial name
- NCT06608589
- Testing
- CoMPAS+ MNCDs Program - Quality improvement program targeting the care transitions of patients living with a major neurocognitive disorder and their caregivers
- Where
- Canada
- Volunteers
- 700 people
- Sponsor
- Laval University
Dysphagia Following Cerebrovascular Accident
Evaluation of Effectiveness of an Interactive Dysphagia Education System for Patients With Stroke
The goal of this clinical trial is to learn if an interactive dysphagia education system can improve swallowing outcomes and quality of life in patients with post-stroke dysphagia.
- Trial name
- NCT07810374
- Testing
- Interactive dysphagia education
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Mei-Yu Lin