Clinical trials: Left Side
Acute Myocardial Infarction (AMI)
Risk Stratification After Acute Myocardial Infarction With Cardiac MRI
Given the existing controversy regarding the appropriate determination time for placement of implantable cardioverter-defibrillator (ICD) in patients at risk for sudden cardiac death (SCD) following acute myocardial infarction…
- Trial name
- CR-2280 (NCT03725826)
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Montefiore Medical Center
Left Ventricular Thrombus
Left Ventricular Thrombus Registry
Left Ventricular Thrombus (LVT) is a blood clot that can develop in a poorly functioning heart. In around 1 in 6 patients who have had a heart attack or diagnosed with heart failure tend to develop blood clots in their main heart…
- Trial name
- LVT Registry (NCT06963567)
- Where
- 8 sites in United Kingdom
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Atrial Fibrillation, Stroke
Amplatzer Amulet LAAO vs. NOAC
The objective of this trial is to evaluate the safety and effectiveness of the Amulet LAA occluder compared to NOAC therapy in patients with non-valvular AF at increased risk for ischemic stroke and who are recommended for…
- Conditions
- Atrial Fibrillation, Stroke, Bleeding
- Trial name
- CATALYST (NCT04226547)
- Testing
- Left Atrial Appendage Occlusion (Amplatzer Amulet LAA Occluder), Non-Vitamin K Oral Antagonists
- Where
- 127 sites in United States, Australia and 14 more
- Volunteers
- 2,650 people
- Sponsor
- Abbott Medical Devices
Leadless Pacemaker, Left Atrial Appendage Occlusion
Combined Leadless Pacemaker and Left Atrial Appendage Occlusion Registry
Leadless pacemakers (LP) are safe and effective alternatives to transvenous pacemakers in selected patients. Implantation is performed with a large caliber delivery catheter.
- Trial name
- NCT06702865
- Where
- Hong Kong
- Volunteers
- 47 people
- Sponsor
- Chinese University of Hong Kong
Heart Failure, Ventricular Assist Device
Influence of Telemonitoring on the Management of LVAD-patients
The current study aims to investigate whether telemedical monitoring in patients with terminal heart failure and an implanted left ventricular assist device (LVAD) has an influence on LVAD-associated complications…
- Conditions
- Heart Failure, Ventricular Assist Device, Telemedicine
- Trial name
- NCT04613401
- Testing
- questionnaire (observational study)
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- University Hospital, Essen
Critical Illness, Elevated Left Atrial Pressure
The Use of Single-Beat TE-e' in Evaluation of Left Atrial Pressure in Critically Ill Patients: The TELAP-ICU Trial
This study evaluates a new single-beat echocardiographic technique (TE-e', the time difference between the onset of the mitral inflow E wave and the septal e' wave on tissue Doppler imaging) for estimating left atrial pressure…
- Conditions
- Critical Illness, Elevated Left Atrial Pressure, Left Ventricular Diastolic Dysfunction, Echocardiography
- Trial name
- TELAP-ICU (NCT07820319)
- Testing
- Echocardiography
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- Queen Mary Hospital, Hong Kong
Heart Failure
Model 20066 Left Ventricular (LV) Lead Study
Heart failure is a progressive disease that decreases the pumping action of the heart. This may cause a backup of fluid in the heart and may result in heart beat changes.
- Trial name
- NCT01365234
- Testing
- Pacing Lead
- Where
- 4 sites in Canada, Malaysia and 1 more
- Volunteers
- 40 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Sudden Cardiac Death Due to Cardiac Arrhythmia, Cardiomyopathies
Personalized Risk Prediction of Sudden Cardiac Death
Sudden cardiac death (SCD) is the final result of cardiac arrest (CA) , defined as an abrupt and unexpected loss of cardiovascular function resulting in circulatory collapse and death.
- Conditions
- Sudden Cardiac Death Due to Cardiac Arrhythmia, Cardiomyopathies, Ischemic Heart Disease, Cardiovascular Diseases
- Trial name
- RESPECT (NCT06321900)
- Testing
- Personalized risk model
- Where
- Italy
- Volunteers
- 1,050 people
- Sponsor
- Istituto Auxologico Italiano
Aortic Valve Stenosis
REST Study: Left Ventricular Regression European Study
The purpose of this study is to obtain data regarding the left ventricular mass (LVM) regression 6 months after the implant of an SJM Epic™ and SJM Epic™ Supra valve by comparing LVM regression measured with magnetic resonance…
- Trial name
- NCT00256165
- Testing
- Tissue valve
- Where
- Germany
- Volunteers
- 150 people
- Sponsor
- Abbott Medical Devices
Emergency Abdominal Surgery, Colorectal Surgery
Effect of Malignancy on Morbidity and Mortality in Left-sided Emergency Colorectal Resections
Patients who underwent emergency left sided colorectal resection in a single center between January 2023 and May 2024 were included.
- Conditions
- Emergency Abdominal Surgery, Colorectal Surgery, Acute Diverticulitis, Volvulus
- Trial name
- NCT06958900
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Complication of Treatment
SEMS Placement Followed by Chemotherapy and Surgery for Obstructing Left-sided Colonic Cancer
This study aimed to evaluate the safety and feasibility of SEMS followed by neoadjuvant chemotherapy prior to elective surgery for obstructing left-sided colon cancer.
- Trial name
- NCT04039360
- Testing
- self-expanding metallic stent placement followed by neoadjuvant chemotherapy
- Volunteers
- 11 people
- Sponsor
- Beijing Chao Yang Hospital
Left Ventricular Thrombosis
Apixaban Versus Warfarin in Patients With Left Ventricular Thrombus
The purpose of this study is to compare the novel oral anticoagulant apixaban with the standard therapy of warfarin on the size reduction or resolution of left ventricular thrombus over 3 months.
- Trial name
- NCT02982590
- Testing
- Apixaban 5 MG Oral Tablet [ELIQUIS], Warfarin Sodium
- Where
- Malaysia
- Volunteers
- 27 people
- Sponsor
- Universiti Sains Malaysia
Surgery, Total Knee Arthroplasty
Enhanced Recovery After Surgery for Total Knee Arthroplasty, Left Colectomy and Hysterectomy
The objective of the study is to assess retrospectively the effect of an awareness-raising phase in favour of Enhanced Recovery After Surgery across the Assistance Publique-Hopitaux Paris institution and to explore the…
- Conditions
- Surgery, Total Knee Arthroplasty, Colectomy, Hysterectomy
- Trial name
- RAAC-AP (NCT03552913)
- Testing
- One year before awareness-raising phase in favour of Enhanced Recovery After Surgery, One year after awareness-raising phase in favour of Enhanced Recovery After Surgery, No specific program toward improving practices
- Where
- France
- Volunteers
- 1,710 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Rectal Cancer, Colon Cancer
Trial on Mechanical Bowel Preparation in Laparoscopic Colorectal Surgery
This is a Randomized trial on Mechanical Bowel Preparation in Laparoscopic Colorectal Surgery. In this trial patients with left sided colon and rectal tumors were randomized to receive mechanical bowel preparation or no…
- Trial name
- MBP (NCT01797770)
- Testing
- polyethylene glycol, No Preparation
- Where
- India
- Volunteers
- 90 people
- Sponsor
- PVS Memorial Hospital
Advanced Refractory Left Ventricular Heart Failure
MOMENTUM 3 Pivotal Cohort Extended Follow-up PAS
The study will be a prospective, multi-center, non-blinded, controlled study, intended to evaluate the extended use of the HM3 LVAS compared to the HMII LVAS in those patients that are ongoing at the 2-year follow-up in the…
- Trial name
- NCT03982979
- Testing
- HM3 LVAS
- Where
- United States
- Volunteers
- 295 people
- Sponsor
- Abbott Medical Devices
Stroke, Rehabilitation
Virtual Reality-Based Upper Limb Rehabilitation in Chronic Stroke
This randomized controlled study aims to evaluate the effectiveness of non-immersive virtual reality-based rehabilitation using the MindMotion™ GO system compared with conventional occupational therapy for improving upper limb…
- Conditions
- Stroke, Rehabilitation, Upper Limb Paresis, Chronic Stroke Patient
- Trial name
- NCT07534124
- Testing
- Non-Immersive Virtual Reality Rehabilitation, Occupational Therapy
- Where
- Spain
- Volunteers
- 26 people
- Sponsor
- Universidad Complutense de Madrid
Hypertension
Valsartan Versus Amlodipine Effect on Left Ventricular Multidirectional Deformation and Adipocytokines Level
Aim: To evaluate the effects of Valsartan versus Amlodipine on LV deformation in relation to plasma adiponectin and leptin levels in hypertensive individuals.
- Trial name
- NCT03990480
- Testing
- valsartan (160 mg/d), amlodipine (10 mg/d).
- Where
- Egypt
- Volunteers
- 230 people
- Sponsor
- Damanhour University
Coronary Artery Disease, Coronary Artery Disease (CAD)
Surgical Versus Percutaneous Revascularization in Patients With Reduced Left Ventricular Function (STICH 3.0-NL)
This randomized multicenter trial compares coronary artery bypass grafting (CABG) with percutaneous coronary intervention (PCI) in 358 patients with ischemic left ventricular dysfunction and multivessel coronary disease.
- Conditions
- Coronary Artery Disease, Coronary Artery Disease (CAD), Multivessel Coronary Artery Disease, CABG
- Trial name
- STICH 3*0-NL (NCT07269366)
- Testing
- CABG, PCI
- Where
- Netherlands
- Volunteers
- 358 people
- Sponsor
- University Medical Center Groningen
Atrial Fibrillation, Atrial Appendage
Assessment of Dual Antiplatelet Therapy Versus Rivaroxaban In Atrial Fibrillation Patients Treated With Left Atrial Appendage Closure
Evaluation of 2 doses of rivaroxaban (10 and 15 mg) compared to dual anti platelet therapy (aspirin+clopidogrel) after left atrial appendage closure.
- Conditions
- Atrial Fibrillation, Atrial Appendage, Hemorrhage
- Trial name
- ADRIFT (NCT03273322)
- Testing
- Rivaroxaban 10 mg qd, Rivaroxaban 15 mg qd, DAPT
- Where
- France
- Volunteers
- 105 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Left Atrial Appendage Closure
Comparison of Amplatzer Amulet and Watchman Device in Patients Undergoing Left Atrial Appendage Closure. (SWISS-APERO)
Left atrial appendage closure (LAAC) is an emerging therapeutic option in non-valvular atrial fibrillation (NVAF) patients with high thromboembolic and bleeding risks.
- Trial name
- SWISS-APERO (NCT03399851)
- Testing
- Amplatzer Amulet for left atrial appendage closure, Watchman/FLX for left atrial appendage closure
- Where
- 8 sites in Belgium, France and 2 more
- Volunteers
- 200 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
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