Clinical trials: Left Ventricular (LV) Systolic Dysfunction
Left Ventricular (LV) Systolic Dysfunction
AI-Enabled Electrocardiogram-Guided Guideline-Directed Medical Therapy on Incident Left Ventricular Dysfunction: A Target Trial Emulation Study
This multicenter retrospective study evaluates whether artificial intelligence-enabled electrocardiography (AI-ECG) can identify individuals at high risk for left ventricular dysfunction and whether targeted guideline-directed…
- Trial name
- NCT07355023
- Testing
- Guideline-directed medical therapies
- Where
- Taiwan
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Tri-Service General Hospital (TSGH)
Mitral Regurgitation
Molecular Mechanisms of Volume Overload-Aim 1(SCCOR in Cardiac Dysfunction and Disease)
The investigators hypothesize that beta-1 receptor blockade (ß1-RB) attenuates extracellular matrix (ECM) degradation and progressive adverse Left Ventricular (LV) remodeling and failure in the volume overload of mitral…
- Trial name
- P1A1 (NCT01052428)
- Testing
- metoprolol succinate (Toprol XL)
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
STEMI - ST Elevation Myocardial Infarction, Left Ventricular Systolic Dysfunction
The Effect of Early Administration of Dapagliflozin in STEMI Patients With LV Systolic Dysfunction
300 STIMI patients with LV systolic dysfunction will be divided into two equal groups (Group I (Study arm, n=150); will receive dapagliflozin plus conventional therapy and group (II) Control arm (n=150); will receive conventional…
- Trial name
- NCT05045274
- Testing
- Dapagliflozin 10Mg Tab
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Assiut University
Heart Failure, Left Ventricular (LV) Systolic Dysfunction
AI-based Prediction of Cardiac Function Using Echocardiography and Body Composition Data (ECHO-FIT Study)
This prospective observational study (ECHO-FIT Study) aims to develop and validate a predictive model for cardiac function, particularly left ventricular ejection fraction (LVEF), by integrating echocardiographic measurements…
- Conditions
- Heart Failure, Left Ventricular (LV) Systolic Dysfunction, Body Composition Measurement, Artificial Intelligence (AI)
- Trial name
- ECHO-FIT (NCT06811519)
- Testing
- Body Composition Analyzer (ACCUNIQ BC720)
- Where
- South Korea
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Yonsei University