Clinical trials: Leg Edema
Gynecologic Cancer
Cross-sectional and Questionnaire Study for Leg Lymphedema
The purpose of this study is to identify the incidence,feature,clinical significance for leg lymphedema after gynecologic cancer treatment.
- Trial name
- NCT02069171
- Volunteers
- 333 people
- Sponsor
- National Cancer Center, Korea
Compresion Therapy, Post-operative Edema
Post-operative Complication, Impulsive Compression, in Situ Bypass
To investigate whether compression therapy with foot pump reduce post-operative edema, facilitate wound healing of operation wounds, promote healing of ischemic ulcers and shorten hospitalization, increase and improve the…
- Conditions
- Compresion Therapy, Post-operative Edema, Wound Complication, Ischemia Limb
- Trial name
- 50506 (NCT03192982)
- Testing
- A-V impulse 6000 Series, Standard treatment (compression)
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Kolding Sygehus
Stroke, Wound Heal
Study of gekoTM Interaction With Cardiac Pacemakers
The gekoTM device is a small disposable battery powered device that attaches to the lower leg near the knee and stimulates the common peroneal nerve, causing muscle contraction of the lower leg.
- Conditions
- Stroke, Wound Heal, Edema Leg, Cardiac Pacemaker Electrical Interference
- Trial name
- NCT04391257
- Testing
- geko™
- Where
- 2 sites in United Kingdom
- Volunteers
- 28 people
- Sponsor
- Firstkind Ltd
Patients With Lower Extremity Venous Ulcers, Patients With Localized Edema
Proof-of-concept Study for Bioimpedance Based Monitoring of Venous Ulcers During Galvanic Stimulation
The research group will choose no more than 10 patients having a lower extremity venous ulcer(s), less than 5cm diameter and with an estimated one month time of re-epithelization.
- Trial name
- NCT02101645
- Testing
- Periodical low intensity direct current (LIDC) stimulation of wound., Compression therapy of swollen limbs.
- Where
- Finland
- Volunteers
- 6 people
- Sponsor
- Tampere University Hospital
Edema, Heart Failure
Effect of Normatec Pump for Relief of Leg Edema
The investigators hypothesize that leg edema will decrease rapidly when using the NormaTec pump, patients will lose weight, will feel better, will be less prone to infections in their legs and to congestion of the liver.
- Conditions
- Edema, Heart Failure, Pulmonary Hypertension
- Trial name
- NCT01112150
- Testing
- NormaTec Pump
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Hillel Yaffe Medical Center
Heart Failure, Edema Leg
Foot Oedema Observed Over Time Study
Heart Failure is the final common pathway of most forms of cardiovascular disease. In the United Kingdom (UK), it affects around 900 000 people, causes or complicates around 5% of adult emergency hospital admissions and consumes…
- Trial name
- FOOT (NCT04072744)
- Testing
- Heartfelt measurements, Connected weighing scales
- Where
- 5 sites in United Kingdom
- Volunteers
- 31 people
- Sponsor
- Heartfelt Technologies
Lipedema, Healthy
Muscle Strength, Muscle Endurance, Lower Extremity Function, Aerobic Capacity, Pressure Pain Threshold and Edema in Women With Lipedema
Lipedema is a chronic progressive disease that causes disproportionate, painful extremities with abnormal fat distribution. Lipedema is known to cause physical and psychosocial disorders in individuals, but there are very limited…
- Trial name
- NCT06866847
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Gazi University
Swelling/ Edema
The Efficacy and Safety of Venostan in Promoting Postoperative Swelling Reduction in Patients With Ankle Fractures
This study is a multicenter, open-label, randomized controlled trial planned to enroll patients with ankle fractures who meet the inclusion and exclusion criteria and are scheduled to undergo internal fixation surgery from the…
- Trial name
- NCT06872034
- Testing
- Venostasin (horse chestnut seed extract tablets), standard treatment
- Where
- China
- Volunteers
- 290 people
- Sponsor
- Beijing Jishuitan Hospital
Heart Failure
Lancashire Objective Volume Evaluation of Leg Oedema in Heart Failure
Patients with heart failure (HF) who recently received treatment with IV diuretics for worsening congestion or outpatients with HF and peripheral oedema treated with at least 80 mg furosemide (or equivalent)/day will be recruited…
- Trial name
- LOVE-HF (NCT04787380)
- Testing
- Heartfelt device
- Where
- United Kingdom
- Volunteers
- 27 people
- Sponsor
- Heartfelt Technologies
Limb Edema, Surgical Site Infections
Prevention of Edema After Coronary Artery Bypass Graft by Customized Pressure-guided Elastic Bandages
The study aimed to assess the efficacy of customized pressure-guided elastic bandages (CPG-EB) in preventing postoperative edema and complications in Coronary Artery Bypass Graft (CABG) patients.
- Conditions
- Limb Edema, Surgical Site Infections, Leg Swelling, Compression Bandages
- Trial name
- PEACCE (NCT06603961)
- Testing
- CPG-EB group
- Where
- 2 sites in Thailand
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Siriraj Hospital
Edema
Mild Compression Sock for Control of Lower Extremity Edema in Individuals With Diabetes
The purpose of this study is to determine whether a specially designed sock for people with diabetes and swelling in the legs can reduce the swelling, improve blood flow to the legs, and improve physical activity patterns of…
- Trial name
- NCT01529385
- Testing
- mild compression diabetic sock, Standard diabetic sock
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Rosalind Franklin University of Medicine and Science
Peripheral Edema
Wireless TENS for Peripheral Edema (Lower Limb Swelling)
This study is single center, subject will receive a wireless TENS device. All subjects will be allowed to keep the commercially-available device for use after the study.
- Trial name
- NCT04680533
- Testing
- Transcutaneous Electrical Nerve Stimulation (TENS)
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Rochester
Diabetes, PAD
Micro-mobile Foot Compression and Diabetic Foot
Diabetic foot ulceration (DFU) is a common and largely preventable complication. While most of these ulcers can be treated successfully, some will persist and become infected.
- Conditions
- Diabetes, PAD, Lower Extremity Edema, Neuropathy;Peripheral
- Trial name
- NCT03135535
- Testing
- Avex Footbeat
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Baylor College of Medicine
Pre-Eclampsia, Volume Overload
PREDICTION OF FLUID RESPONSIVENESS WITH PASSIVE LEG RISING IN PREGNANT PATIENTS WITH SEVERE PREECLAMPSIA
BACKGROUND: A cornerstone of treatment in preeclampsia is to correct the potential hypovolemia with intravascular optimisation, which is usually performed as a fluid challenge.
- Conditions
- Pre-Eclampsia, Volume Overload, Hemodynamic Instability
- Trial name
- NCT03755843
- Testing
- PASSIVE LEG RISING
- Where
- Mexico
- Volunteers
- 35 people
- Sponsor
- RAUL CARRILLO ESPER
Ankle Fractures, Swelling
Effect of Cool Spray and Cold Packs in Reducing Preoperative Edema and Pain in Ankle Fractures in Ubonratchathani
The use of evaporative coolants in the management of acute musculoskeletal injury has received increasing attention recently. However, its efficacy compared with conventional cryotherapy in treating injured human subjects remains…
- Conditions
- Ankle Fractures, Swelling, Cryotherapy Effect
- Trial name
- 3-armRCT (NCT06293209)
- Testing
- 3M cold pack, Perskindol cold spray
- Where
- Thailand
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Thai Traditional Medical Knowledge Fund
Edema Leg
The Effect of Compression Stockings on Edema and Discomfort During Short Haul Flights
Compression stockings have beneficial effects on the development of venous thromboembolic complications and oedema during long- haul flights.
- Trial name
- NCT03546725
- Testing
- Compression stocking
- Where
- Denmark
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Herlev and Gentofte Hospital
Varicose Veins of Lower Limb, Varix
Effects of Bioflavanoids on Vascular Wall Remodeling in Patients With Varicose Veins
The study is aimed at assessing the dynamics of changes in biochemical markers of venous wall remodeling (type 1 plasminogen activation inhibitor (PAI-1), fibronectin (fibronectin, FN), vimentin (vimentin, VM), von Willebrand…
- Conditions
- Varicose Veins of Lower Limb, Varix, Vascular Diseases, Leg Edema
- Trial name
- NCT06367166
- Testing
- "Venarus®" (diosmin and hesperidin), Endovenous laser ablation (EVLA) with miniphlebectomy, Elastic compression
- Where
- Russia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ryazan State Medical University
Lymphedema, Lower Limb, Extracorporeal Shock Wave Therapy
Extracorporeal Shock Wave Therapy in Lower Extremity Lymphedema
Lower extremity lymphedema is a chronic and progressive condition associated with significant functional impairment and reduced quality of life.
- Conditions
- Lymphedema, Lower Limb, Extracorporeal Shock Wave Therapy, Edema Leg, Sham-controlled
- Trial name
- NCT07626645
- Testing
- Extracorporeal Shock Wave Therapy (ESWT)
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Gazi University
Lower Extremity Edema, Congestive Heart Failure(CHF)
Pedal Pump Clinical Trial on Edema V1
Previous research on the osteopathic manual technique entitled "Pedal Pump" has shown health benefits, specifically increasing lymphatic flow, decreasing lower extremity edema, and decreasing serum lactic acid after maximal…
- Conditions
- Lower Extremity Edema, Congestive Heart Failure(CHF), Chronic Venous Insufficiency (CVI), Kidney Disease
- Trial name
- NCT07760363
- Testing
- Pedal Pump
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- David McVay
Amputation Stump, Peripheral Vascular Disease With Complications
Comparison Between Postoperative Tubular Dressing and a Vacuum Removable Rigid Dressing After Transtibial Amputation
Comparison of wound healing, edema level, knee range of motion, rate of revision post falls, device application time, time to prosthetic fit, and cost between postoperative soft dressing and a vacuum removable rigid dressing…
- Conditions
- Amputation Stump, Peripheral Vascular Disease With Complications, Edema Leg, Wound Healing Delayed
- Trial name
- EMPAR (NCT03948087)
- Testing
- Vacuum Removable Rigid Dressing (VRRD)
- Volunteers
- 100 people
- Sponsor
- Covenant Health, Canada