Clinical trials: Leg Fracture
Ankle Fractures
Operative Versus Non Operative Management Outcomes of Isolated Lateral Malleolar Weber B Ankle Fractures
The primary objective of this study is to determine the failure rate and difference in clinical outcomes between operative and non operative treatment of patients with Weber B lateral malleolus ankle fractures with medial clear…
- Trial name
- NCT03625154
- Testing
- ankle open reduction internal fixation, non operative management
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Femoral Neck Fractures
Osseointegration of Hydroxyapatite-coated Femoral Stems in Femoral Neck Fractures Over 80 Years
This study aimes to prove that osseointegration of hydroxyapatite coated stem is possible for patients over 80 years with femoral neck fracture, without the risks of cemented stems.
- Trial name
- NCT04773145
- Testing
- Hemiarthroplasty with hydroaxyapatite coated stem
- Where
- France
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Hip Fractures
Comparative Study to Evaluate the Efficacy of Ultrasound-Guided Pericapsular Nerve Group (PENG) Block Versus Fascia Iliaca Compartment (FIC) Block on the Postoperative Analgesic Effect in Patients Undergoing Hip Surgeries Under Spinal Anesthesia.
Fractures in and around the hip are quite common irrespective of both the young and elderly population groups and are associated with extreme pain.
- Trial name
- NCT05751291
- Testing
- Bupivacaine Hydrochloride
- Where
- Egypt
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Sohag University
Trochanteric Fractures
Treatment Of Unstable Trochanteric Fracture: A Comparative Study Between DHS And DHS With Trochanteric Stabilization Plate
compare the results in treatment of unstable trochanteric fracture by using DHS and DHS with Trochanteric Stabilizing plate as regard shaft medialization.neck shaft angle measurment and shaft migration
- Trial name
- NCT05781815
- Testing
- dynamic hip screw
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sohag University
Gait Analysis, Hip Fractures
Gait Pattern Between a Cemented and Non-cemented Femur Stem
Acute cervical femoral neck fracture patients randomized to either cemented or non-cemented stem. The investigators used gait analysis to evaluate if patients operated with a cemented stem showed more favourable hip kinematics…
- Conditions
- Gait Analysis, Hip Fractures, Hip Arthroplasty, Randomized
- Trial name
- NCT04791605
- Testing
- Gait analysis
- Where
- Sweden
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Fractured Neck of Femur
Single Dose of Dexamethasone in Femur Fractures
Fracture neck of femur is a common cause of hospital admission in the elderly and requires operative fixation. Dexamethasone has the potential of inhibiting cortisol secretion.
- Trial name
- NCT01550146
- Testing
- Dexamethasone acetate
- Where
- Ireland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cork University Hospital
Osteoarthritis, Spinal Diseases
The Effect of AposTherapy on the Level of Pain, Function and Quality of Life in Patients With Neuro-muscular and Neurological Disorders
The purpose of the study is to examine the effect of a new biomechanical device and treatment methodology (AposTherapy) on gait patterns, pain, function and quality of life of patients with musculoskeletal and neurological…
- Conditions
- Osteoarthritis, Spinal Diseases, Ligament Rupture, Lower Extremity Fracture
- Trial name
- NCT01266382
- Testing
- AposTherapy
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Ankle Fractures, Splints
Post Operative Ankle Splint Study - Prospective Multi Center Randomized Controlled Trial
Background: Ankle fractures are some of the most common orthopedic presentations, however, controversy in their management and their post-operative rehabilitation protocols exist.
- Trial name
- PASS (NCT04796168)
- Testing
- Splinting (plaster of paris)
- Where
- Kuwait
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Kuwait Institute for Medical Specialization
Femur Fracture
Spica Casting in Pediatric Femur Fractures: Study of Single Leg Versus Double Leg Spica Casts
Prospective randomized controlled trial comparing use of single leg spica with double leg spica casts in the treatment of pediatric femur fractures in children ages 2 through 6 years old.
- Trial name
- NCT01293916
- Testing
- Spica casting
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Tibia Fracture
Ilizarov Frame or Uni Planar External Fixator in the Cost-conscious Era
Tibial shaft fracture is a common injury worldwide. Their treatment, prognosis, and outcome are determined by the mechanism of injury, presence of communition, soft tissue injury and displacement.
- Trial name
- NCT03936972
- Testing
- ilizarov circular frame and uni-planarexternal fixator
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Acetabular Fracture, Pelvic Fracture
Hip Strength and Nerve Palsy After the Modified Stoppa Approach to Acetabular Fracture Reduction and Fixation
The purpose of this prospective study is to compare hip adductor strength and obturator nerve palsy between acetabular fracture patients whose fracture was reduced and fixated using the modified Stoppa approach (subjects) and…
- Trial name
- NCT01763359
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Utah
Post-traumatic; Arthrosis, Tibial Fractures
Does Joint Lavage Reduce Intraarticular Inflammation in High-energy Tibial Pilon Fractures?
High-energy tibial pilon fractures have historically been associated with poor outcomes largely due to the elevated risk of severe post-traumatic arthritis.
- Conditions
- Post-traumatic; Arthrosis, Tibial Fractures, Post-Traumatic Osteoarthritis of Ankle
- Trial name
- NCT05652881
- Testing
- Joint Lavage
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, San Diego
Femoral Fracture
Retrograde Femoral Nail-Advanced Outcomes for Fixation of Distal Femur and Femoral Shaft Fractures
This project consists of a prospective and retrospective case series design. Study candidates will include all patients 18 years or older, who were evaluated at UCSD and found to have a distal femur or femoral shaft fracture…
- Trial name
- NCT05680987
- Testing
- RFN-Advanced Retrograde Femoral Nailing System
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Hip Fracture
PUSH Plus Protein Pilot for Hip Fracture Patients
Hip fracture is a common problem among older individuals. The goal of current standard of care after hip fracture is to achieve independent, household ambulation 2-3 months after surgery, yet decreased functional ability…
- Trial name
- NCT03410823
- Testing
- PUSH, Protein, Nutrition
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Myocardial Infarction, Stroke
Women's Health Initiative Strong and Healthy Study
The WHISH trial applies state-of-the science behavioral principles and currently available technologies to deliver a physical activity intervention without face-to-face contact to ~25,000 older U.S. women expected to consent.
- Conditions
- Myocardial Infarction, Stroke, Cardiovascular Mortality, Hip Fractures
- Trial name
- WHISH (NCT02425345)
- Testing
- Physical Activity
- Volunteers
- 49,331 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Hip Fractures
Patient-Centered Education After Hip Fracture Surgery
This randomized controlled trial aims to evaluate the effect of a structured patient-centered educational program on postoperative outcomes among patients undergoing hip fracture surgery.
- Trial name
- PCE-HFS (NCT07739225)
- Testing
- Structured Patient-Centered Educational Program.
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Accidental Fall, Fall
Remote Monitoring and Analysis of Gait and Falls Within an Elderly Population
The investigators aim to do this initial pilot study as an observational prospective cohort study, evaluating elderly patients who have capacity in National Health Service (NHS) rehabilitation and community hospitals.
- Conditions
- Accidental Fall, Fall, Fall Injury, Hip Fractures
- Trial name
- 4279 (NCT03680014)
- Testing
- CUSH
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- CUSH Health Ltd.
Hip Fractures, Anticoagulants and Bleeding Disorders
Caudal Block & Hip Fracture Surgery in Anticoagulated Patient
Hip fractures are common in elderly patients, and require surgery. Many elderly patients take anticoagulants for vasculopathy treatment.
- Trial name
- NCT05946863
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Salem Anaesthesia Pain Clinic
Hip Fractures, COVID-19
Anesthesia Technique in COVID-19 Positive Hip Fracture Patients
Patients with COVID undergoing hip fracture repair have high mortality rates. If spinal anesthesia is associated with decreased rates of mortality, this study could provide hypothesis generating data for prospective studies.
- Conditions
- Hip Fractures, COVID-19, General Anesthesia, Spinal Anesthesia
- Trial name
- NCT05133648
- Testing
- Hip Fracture Surgery, COVID-19 infection
- Where
- Canada
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Pelvic Fracture
Outcome of the Anterior Subcutaneous Internal Fixator (INFIX) for Pelvic Ring Disruptions
With a prospective case series study of 15 patients The aim of this study is to estimate the clinical outcomes in patients with unstable anterior pelvic ring fractures ( B\&C ) after treatment with (INFIX)
- Trial name
- NCT05354531
- Testing
- anterior subcutaneous internal fixator ( INFIX)
- Where
- 2 sites in Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Assiut University