Clinical trials: Leg Injuries
Arthroscopy, Tibial Fractures
Arthroscopic Assisted Balloon Tibioplasty for the Treatment of Schatzker II-IV Tibial Plateau Fractures
The investigators use existing resources to carry out this new technology, in accord with the standard of the patients, were randomized to traditional fracture balloon tibia fixation or arthroscopic reduction under angioplasty…
- Conditions
- Arthroscopy, Tibial Fractures, Orthopedic, Fracture Fixation
- Trial name
- AABTFTPF (NCT03327337)
- Testing
- Arthroscopic Assisted Balloon Tibioplasty
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Overuse Injuries, Musculoskeletal Make-up in the Lower Extremities
Knowledge of Predicting Increased Risk for an Overuse Injury in Runners
The purpose of this study is to examine the skeleton of the legs and the running style in order to predict a possible overuse injury.
- Trial name
- NCT01979562
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Northern Orthopaedic Division, Denmark
Health Behavior, Muscle Strain, Lower Leg
Effect of Tissue Flossing on Recovery Time After Intense Physical Exercise Causing Delayed Onset Muscle Soreness
The aim of the study is to assess whether soft tissue flossing therapy will alleviate eccentric muscle-destroying influences. Men aged 20-25 will be tested.
- Trial name
- NCT05684315
- Testing
- soft tissue flossing therapy
- Where
- Poland
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Józef Piłsudski University of Physical Education
Anterior Cruciate Ligament Injuries
Effect of Visual-Guided Balance Training on Knee Motor Function and Biomechanical Characteristics After ACL Reconstruction
This study aims to investigate the improvement effect of visual-guided balance training on the knee joint function and gait performance of patients after ACLR, and to clarify the advantages of this training program compared to…
- Trial name
- NCT07306221
- Testing
- Traditional group, Intervention Group
- Where
- China
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Non-Diabetic Patients, Wound Leg
Role of Tissue Oxygenation and the miR-210 Gene In Wound Healing
Hypothesis: Elevated miR210 in the epidermis (outer layer of skin) of ischemic human wound edge tissue (tissue that has a lack of blood flow to it) is associated with poor healing outcome in a setting of standard clinical care.
- Conditions
- Non-Diabetic Patients, Wound Leg, Chronic Ulcer Leg/Foot
- Trial name
- miR210 (NCT02024243)
- Where
- 3 sites in United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Chandan Sen
Musculoskeletal Injury, Anterior Cruciate Ligament Injuries
Micro-Doppler Radar: A Gold Standard Comparison
The purpose of this study is to see if the study team can use micro-Doppler signal (MDS) technology to determine if someone has had an anterior cruciate ligament (ACL) reconstruction.
- Trial name
- NCT05521126
- Where
- 2 sites in United States
- Volunteers
- 181 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Ankle Injuries
Lateral Ankle Sprain and Platelet Rich Plasma
Lateral ankle sprains are one of the most common in sports medicine. Considering the sprains in general, they represent an 85% of the ankle lesions. The incidence in high performance athletes range from 16 to 21%.
- Trial name
- NCT02609308
- Testing
- Short leg cast, Platelet-rich plasma
- Where
- Mexico
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Nuevo Leon
Leg Injuries
Smart Phone as a Screening and Evaluation Tool to Identify Knee Valgus During Dynamic Activities
Evidence supports the use of two dimensional video analysis to assess the presence of dynamic knee valgus during generally used screening tasks, however there is limited evidence to support the use of the various smart phone…
- Trial name
- NCT02167399
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Mitchell Selhorst
Chronic Instability of Ankle Joint, Dynamic Balance
Differences in Ankle Sprain Risk Factors, Anterior Talofibular Ligament, Calcaneofibular Ligament and Lower Leg Muscles' Size Among Athletes With and Without Ankle Sprain Injury History: A Retrospective Study
This study aims to comprehensively explore the relationship between changes in muscle architecture and connective tissue structure in athletes with ankle sprains and the intrinsic biomechanical risk factors observed in these…
- Conditions
- Chronic Instability of Ankle Joint, Dynamic Balance, Muscle Size
- Trial name
- NCT07579793
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Yeditepe University
Amputation Wound, Traumatic Amputation of Toe
Longitudinal Study of Weight Change Following Lower Limb Amputation
The purpose of this study is to assess weight change in a population of Veterans with amputations. Little is known about the how weight changes following an amputation.
- Conditions
- Amputation Wound, Traumatic Amputation of Toe, Dysvascular Amputation of Lower Limb
- Trial name
- NCT00932399
- Where
- United States
- Volunteers
- 4,549 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
ACL Injuries
Menstrual Cycle-Synced Neuromuscular Training
This is a research study of female athletes participating in at least one running/cutting sport, who have no current conditions that would limit ability to perform sport-like movement tasks (such as running or jumping), and have…
- Trial name
- NCT06983184
- Testing
- MC-synced NTP, Blinded NTP
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Sophia Ulman
Osteoarthritis, Knee, Anterior Cruciate Ligament Injuries
Development of Computational Models to Predict the Short-, Medium- and Long-term Cartilage Degeneration and Pain for Patients With Early-stage Osteoarthritis or Anterior Cruciate Ligament Injury
Knee osteoarthritis is a complex condition, and selecting effective non-drug treatments like orthoses or exercise is often difficult and imprecise.
- Trial name
- MathKOA (NCT07134244)
- Where
- 2 sites in Denmark
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Osteoporosis, Achlorhydria
Does Omeprazole Decrease Intestinal Calcium Absorption?
The purpose of this study is to measure the effect of omeprazole on intestinal calcium absorption in postmenopausal women.
- Conditions
- Osteoporosis, Achlorhydria, GERD, Hip Fracture
- Trial name
- NCT00582972
- Testing
- Omeprazole
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Femoral Neck Fractures
Open Reduction in Femoral Neck Fractures
Outcomes of open reduction and internal fixation of femoral neck fractures using dynamic hip screw versus cannulated screws combined with medial buttress plate.
- Trial name
- OR FNFS (NCT06872970)
- Testing
- Open reduction of femoral neck fractures and internal fixation by dynamic hip screws, Open reduction of femoral neck fractures using watson jones or smith peterson approachand internal fixation by cannulated screws and medial buttress plate
- Where
- Egypt
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Samer youssef mansour meglaa
Tibial Fractures, Malleolar Fractures
Intramedullary Nailing of Tibia Fractures
Currently, the treatment of choice for tibial fracture is intramedullary nailing. This procedure has been shown to have low rates of infection, high rates of bone healing, and a faster return to weight bearing and activity in…
- Trial name
- NCT01797640
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Utah
Injury, Knee, Injury, Ankle
Prevention of Patellar and Achilles Tendinopathies in Youth Basketball
This study seeks to determine the prevalence of knee and ankle tendinopathies in youth basketball players, as well as determine the efficacy of a Basketball specific Neuromuscular training warm-up in reducing injuries.
- Conditions
- Injury, Knee, Injury, Ankle, Tendinopathy, Sports Injuries in Children
- Trial name
- NCT04363398
- Testing
- Comprehensive Follow-up, Standard Follow-up
- Where
- Canada
- Volunteers
- 441 people, healthy volunteers welcome
- Sponsor
- Sport Injury Prevention Research Centre
Diabetic Foot Ulcers
Safety Study of Topical Human FGF-1 for Wound Healing
The purpose of the study is to see if FGF-1 is safe when applied topically to the surface of a wound.
- Trial name
- NCT00916292
- Testing
- FGF-1 141
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Phage Pharmaceuticals, Inc.
Anterior Cruciate Ligament Rupture
Risk Factor of Anterior Cruciate Ligament Rupture After Ligamentoplasty : What is the Importance of a Relative Deficit of Contralateral Hamstrings Assessed by Isokinetic in Postoperative ?
Anterior cruciate ligament (ACL) is a common pathology (37 000 operations in 2006, nearly 43 000 in 2012 in France) justifying more and more operating indications in younger and younger patients.
- Trial name
- DIS-RRACT (NCT03668210)
- Testing
- Isokinetic evaluation
- Where
- France
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
Diabetic Retinopathy, Macular Degeneration
Advancing Understanding of Transportation Options
This Stage II randomized, controlled, longitudinal trial seeks to assess the acceptability, feasibility, and effects of a driving decision aid use among geriatric patients and providers.
- Conditions
- Diabetic Retinopathy, Macular Degeneration, Glaucoma, Retinitis Pigmentosa
- Trial name
- AUTO (NCT04141891)
- Testing
- Driving Decision Aid, Older Drivers Website
- Where
- 3 sites in United States
- Volunteers
- 529 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Punch Biopsy Wounds, Healing Times
Healing of Punch Graft Wounds. Comparative Study Between MariGen and Oasis: a Non-inferiority Study
The objective is to determine, if healing of punch biopsy wounds treated with the fish skin derived MariGen Wound dressing is non-inferior to healing with wounds treated with pig intestines derived Oasis Sheet wound dressing.
- Trial name
- NCT01917591
- Testing
- Punch biopsies treated with MariGen Wound ECM dressing, Punch biopsies treated with Oasis ECM dressing
- Where
- Iceland
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Kerecis Ltd.