Clinical trials: Leg Injuries and Disorders
Venous Ulcer
Silica Gel Fiber Wound Dressing for Chronic Venous Leg Ulcers
Silica Gel Fiber is a bioresorbable, inorganic silica gel fibre patch promoting skin tissue growth and enhanced wound healing for all types of chronic wounds.
- Trial name
- NCT00998673
- Testing
- Silica Gel Fiber, Standard-of-Care
- Where
- 14 sites in Germany
- Volunteers
- 121 people
- Sponsor
- Bayer
Arthritis, Femoroacetabular Impingement
Conjoint Analysis of Patient Preferences in Joint Interventions
This study is an observational study to test and validate a questionnaire and statistical model used to determine patient preferences regarding treatment for any one of 11 musculoskeletal conditions: hip arthritis, knee…
- Conditions
- Arthritis, Femoroacetabular Impingement, Osteochondritis Dissecans, Hip Fractures
- Trial name
- NCT02664337
- Testing
- Decision tool, Standard treatment information
- Where
- United States
- Volunteers
- 2,310 people
- Sponsor
- Duke University
Diabetic Foot Ulcers (DFUs), Diabetic Foot
Miro3D Wound Matrix for Treatment of Diabetic Foot Ulcers
This study is designed to evaluate whether the Miro3D Wound Matrix, when used in addition to standard of care, improves healing outcomes in patients with chronic diabetic foot ulcers.
- Conditions
- Diabetic Foot Ulcers (DFUs), Diabetic Foot, Chronic Wounds
- Trial name
- FOCUS 3D (NCT07632001)
- Testing
- Miro3D Wound Matrix, Standard of Care
- Where
- 14 sites in United States
- Volunteers
- 180 people
- Sponsor
- Reprise Biomedical, Inc.
Anaemia, Myocardial Ischaemia, Fractured Neck of Femur
Cardiac Injury and Anaemia Following Surgery for Fractured Neck of Femur: An Observational Study Study Protocol: Cardiac Injury and Anaemia Following Surgery for Fractured Neck of Femur
Blood transfusion is an expensive and finite resource and optimum transfusion threshold in surgical patients is yet to be defined.
- Trial name
- NCT02969811
- Volunteers
- 47 people
- Sponsor
- NHS Lothian
Fracture of Pelvis (Disorder)
Abaloparatide and Pelvic Fracture Healing
This is a prospective randomized, double-blinded, placebo-controlled, phase 2, three-month study of the efficacy of abaloparatide in postmenopausal women and men ≥ 50 years of age with acute fractures of the pelvis (n=78).
- Trial name
- NCT04249232
- Testing
- Abaloparatide 80 micrograms per Pen dose
- Where
- 3 sites in United States
- Volunteers
- 48 people
- Sponsor
- Hospital for Special Surgery, New York
Iliotibial Band Syndrome
Clamshell and Frog Pump Exercises on Pain, Range of Motion, and Functional Disability
The study will be randomized clinical trial. This study will be conducted at the University of Lahore Teaching Hospital, Lahore, Pakistan.
- Trial name
- NCT07118371
- Testing
- Clamshell exercise, Frog pump exercises
- Where
- Pakistan
- Volunteers
- 92 people
- Sponsor
- University of Lahore
Old Age, Hip Fractures
Validity and Reliability of the Modified Delirium Diagnostic Tool - Provisional (DDT-Pro) (Thai Version) in Peri-operative Fragility Hip Fracture Patient
Nowadays, the number of hip fracture patients is increasing. As Thailand enters into an aging society, hip fractures are becoming more common. They are typically treated with surgery.
- Conditions
- Old Age, Hip Fractures, Delirium
- Trial name
- NCT06504251
- Testing
- Delirium Diagnostic Tool-Provisional ( DDT-Pro )
- Where
- Thailand
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Post-Traumatic Osteoarthritis of Knee, Knee Injuries
Changes in the Immunomodulatory Properties of Adipose Stromal Cells Due to Hemarthrosis After Knee Injury
The goal of this observational study is to gain insight in the natural course of pro-inflammatory factors and hemarthrosis in patients older than 18 with a recent knee trauma.
- Conditions
- Post-Traumatic Osteoarthritis of Knee, Knee Injuries, Hemarthrosis
- Trial name
- CASH (NCT05687331)
- Testing
- knee arthrocentesis, venipuncture, MRI-scan
- Where
- Netherlands
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Hip Injuries, Coxarthrosis
Balance and Leg Function After Hip Replacement
Task-oriented leg exercise are commonly used after joint surgeries in various hip pathologies. Based on this theory, it was hypothesized that task-oriented exercise without conventional physiotherapy can have better result in…
- Conditions
- Hip Injuries, Coxarthrosis, Hip Replacement
- Trial name
- NCT05343195
- Testing
- Task-oriented exercise, Control
- Where
- Lithuania
- Volunteers
- 40 people
- Sponsor
- Lithuanian Sports University
Bony Weight Bearing Disorder
Safety of Immediate Weight-Bearing as Tolerated After Well-Reduced Geriatric Hip
Purpose: Proximal femur fracture is a major traumatic injury in elderly populations; however, practical postoperative weight-bearing protocols are lacking.
- Trial name
- NCT06199739
- Testing
- Early-Weight bearing
- Where
- Taiwan
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Far Eastern Memorial Hospital
Stress, Job, PTSD
The Sequestration of Holistic Stress Management Techniques for Adults
This remote study is intended to assist the population with access to cost-effective pastoral counseling for stress management in the workplace and every day life.
- Conditions
- Stress, Job, PTSD, Hypervigilance, Hyperthyroidism
- Trial name
- NCT06098755
- Testing
- Holistic Medicine (HM)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Goddess Zena I. Jones
Knee Osteoarthritis
Exploring Factors Linked to Worsening Over Time in People With Early-stage Knee Osteoarthritis and Those With Prior Proven Acute Knee Injury.
The goal of this observational, non-interventional cohort study is to identify tests or markers in blood or knee fluid, or any genetic risk factors that might contribute to worsening or improvement of knee osteoarthritis.
- Trial name
- KNEE (NCT07833488)
- Where
- United Kingdom
- Volunteers
- 200 people
- Sponsor
- Imperial College London
Fracture of Hip, Ileus
Peripheral Perfusion Index, Haemoglobin and Blood Transfusion in Acute Surgical Patients
The peripheral perfusion index (PPI) is a non-invasive, feasible measure of peripheral perfusion and, assumed, the overall circulation, which all patients are monitored by.
- Conditions
- Fracture of Hip, Ileus, Perforated Viscus, Anastomotic Leak
- Trial name
- NCT03795467
- Where
- Denmark
- Volunteers
- 1,500 people
- Sponsor
- Hvidovre University Hospital
Diabetic Foot Ulcer
RCT Comparing Upper Body vs. Combined Exercise Protocols During Active Diabetic Foot Ulcer Treatment
This randomized controlled trial (RCT) aims to evaluate the effectiveness of two different structured exercise interventions compared to standard care during active diabetic foot ulcer (DFU) treatment.
- Trial name
- NCT06916663
- Testing
- Upper Body Exercise Protocol (UBE), Combined Non-Weight Bearing Exercise Protocol (CE), Standard Diabetic Foot Ulcer Wound Care (SC)
- Where
- Egypt
- Volunteers
- 153 people
- Sponsor
- Al Hayah University In Cairo
Diabetic Foot, Wound Heal
The Effect of Combined 650 nm and Infrared Laser on Chronic Diabetic Foot Ulcer Surface Area:
Objective: investigate the effect of combined 650 nm and infrared laser on chronic diabetic foot ulcer surface area. Participants: The forty five patients will assigned randomly into three equal groups, each group consist of 15…
- Trial name
- wounds (NCT05517863)
- Testing
- laser therapy
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Heidy F. Ahmed
Diabetic Foot Ulcer
Comparative Study of Amniotic Membrane Wound Graft In the Management of Diabetic Foot Ulcers
The purpose of this study is to determine whether the EpiFix human amniotic membrane is effective in the treatment of diabetic foot ulcers.
- Trial name
- NCT01552499
- Testing
- Standard of care, Applications of EpiFix
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- MiMedx Group, Inc.
Kinesiophobia, ACL Injury
Kinesiophobia After Anterior Cruciate Ligament Reconstruction.
Anterior cruciate ligament (ACL) rupture is a serious trauma with long-term consequences to the athlete. Psychological and physiological factors may negatively affect patient recovery and increase reinjury rate after anterior…
- Trial name
- NCT05762809
- Testing
- Tampa Scale of Kinesiophobia (TSK-17), Knee injury and Osteoarthritis Outcome Score (KOOS), Oxford Knee Score (OKS) scoring
- Where
- Estonia
- Volunteers
- 144 people
- Sponsor
- Tartu University Hospital
Osteoarthritis of the Knee, Degenerative Osteoarthritis
Platelet-Rich Plasma and the Effects of NSAIDs on Pain and Functional Scores in Knee Osteoarthritis
The primary research purpose is to determine if the use of a drug therapy intervention (each study participant will be randomly assigned to receive one of 3 study medications which will be blinded from everyone, including the…
- Conditions
- Osteoarthritis of the Knee, Degenerative Osteoarthritis, Knee Pain Chronic
- Trial name
- PRPNSAIDsKOA (NCT05742763)
- Testing
- Ibuprofen and PRP, Acetaminophen and PRP
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- QC Kinetix LLC
Chronic Ankle Instability, Ankle Sprain
Collagen Scaffold Bioaugmentation for ATFL Repair in Chronic Ankle Instability
This is a multicenter, randomized, controlled clinical trial comparing two surgical techniques for the treatment of chronic ankle instability (CAI).
- Conditions
- Chronic Ankle Instability, Ankle Sprain, Joint Instability
- Trial name
- REAR (NCT07878312)
- Testing
- Arthroscopic Anterior Talofibular Ligament Repair, Internal Brace Augmentation, REGENETEN Bioinductive Collagen Scaffold
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Slipped Capital Femoral Epiphysis
Management of Slipped Capital Femoral Epiphysis (SCFE) on Top of Fixed Fracture Neck of Femur Case Report.
Slipped Capital Femoral Epiphysis (SCFE) on Top of Fixed Fracture Neck of Femur managed by subtrochanteric valgus osteotomy
- Trial name
- SCFE (NCT05758051)
- Testing
- subtrochanteric valgus osteotomy
- Where
- Egypt
- Volunteers
- 1 people
- Sponsor
- Assiut University
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