Clinical trials: Leg Lymphedema
Lymphedema
CVR Registry Evaluating Flexitouch Plus and Conservative Care vs Conservative Care Only for Treatment of Lymphedema
Subjects with lower extremity lymphedema will be prescribed, per standard of care, to either Flexitouch Plus with conservative care or conservative care only and be followed for 12 months.
- Trial name
- NCT04116099
- Testing
- Conservative care, Flexitouch Plus
- Where
- 3 sites in United States
- Volunteers
- 63 people
- Sponsor
- Tactile Medical
Lymphoedema, Breast Cancer
Spa Therapy for Upper or Lower Limb Lymphoedema
THERMOEDEME is a comparative, controlled, randomized, multicenter and simple blinded (investigator) trial. The aim of this study is to evaluate effects of spa therapy in phlebology with a therapeutic education program in daily…
- Conditions
- Lymphoedema, Breast Cancer, Malignant Disease, Gynaecological Cancer
- Trial name
- THERMOEDEME (NCT03580109)
- Testing
- Immediate spa treatment, Late spa treatment
- Where
- 13 sites in France
- Volunteers
- 160 people
- Sponsor
- Association Francaise pour la Recherche Thermale
Post Thrombotic Syndrome
Treatment Trial for Post-Thrombotic Syndrome
The purpose of this study is to determine if complex lymphedema therapy is effective in decreasing disease severity and improving quality of life in patients with post thrombotic syndrome.
- Trial name
- NCT00633971
- Testing
- complex lymphedema therapy
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Vermont
Lymphedema, Secondary, Lymphedema of Leg
Secondary Lymphedema Due to Human Adjuvant Disease
This observational, descriptive, retrospective study the clinical and imaging findings of 10 lower legs of 5 patients with previous history of injection of modeling substances for cosmetic purposes at buttocks and hips ande…
- Conditions
- Lymphedema, Secondary, Lymphedema of Leg, Granuloma, Foreign-Body
- Trial name
- NCT04588493
- Testing
- Lower extremity Lymphoscintigraphy
- Where
- Mexico
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Hospital Angeles del Pedregal
Lymphedema of Leg, Lymphedema
Inspiratory and Calf Muscles Training in Patients With Leg Lymphedema
Lymphedema results in the accumulation of protein-rich fluid in the subcutaneous tissue as a result of the failure of the lymphatic system, which returns water and protein in the interstitial spaces to the bloodstream.
- Conditions
- Lymphedema of Leg, Lymphedema, Exercise
- Trial name
- NCT05609526
- Testing
- Compression Therapy, Inspiratory muscle training, Calf muscle exercise training
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Diabetic Foot, Pressure Ulcer
A Real-World Registry of Chronic Wounds and Ulcers
WOUNDJOURNEY is a longitudinal, real-world, observational registry designed to capture the full clinical course and patient journey associated with chronic wounds and ulcers.
- Conditions
- Diabetic Foot, Pressure Ulcer, Surgical Wound Dehiscence, Vasculitis
- Trial name
- WOUNDJOURNEY (NCT02280733)
- Testing
- Usual care
- Where
- United States
- Volunteers
- 300,000 people
- Sponsor
- U.S. Wound Registry
Lower Extremity Lymphedema, Endometrial Cancer
Lymphedema in Endometrial Cancer
Objectives: (1) To determine the incidence of lower-extremity lymphedema after staging surgery for endometrial cancer; (2) to describe lymphedema-related morbidity after staging surgery for endometrial cancer and (3) to evaluate…
- Trial name
- NCT01914276
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Duke University
Lymphoedema of Leg
Intermittent Pneumatic Compression for Treating Lower Limb Lymphoedema
The treatment of lymphoedema and its associated complications represent a considerable drain on increasingly limited NHS resources.
- Trial name
- IMPRESS II (NCT03856281)
- Testing
- Intermittent Pneumatic Compression
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Cwm Taf University Health Board (NHS)
Lymphedema
Causes of Kinesiophobia in Lymphedema
In this study, the reason for the fear of movement in patients with lymphedema will be investigated and recommendations will be given to the patients to eliminate it.
- Trial name
- NCT05105594
- Testing
- survey application
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Lower Extremity Lymphedema
Effectiveness of Digital Physiotherapy in the Short and Long-Term Management of Lower Extremity Lymphedema
This study investigated the short- and long-term effects of digital physiotherapy in patients with unilateral and bilateral lower extremity lymphedema.
- Trial name
- NCT07014566
- Testing
- Digital Combined Decongestive Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Bezmialem Vakif University
Chronic Edema, Lymphedema
Boosted Compression for Lower Limb Chronic Edema
Patients: Patients targeted in this proposal comprise individuals afflicted by chronic edema/lymphedema of the lower limbs. Intervention: The intervention entails the incorporation of boosted compression alongside standard care…
- Trial name
- BECOME (NCT07708662)
- Testing
- Conservative edema treatment (complex decongestive therapy), Conservative edema treatment with boosted compression therapy
- Where
- 4 sites in Belgium
- Volunteers
- 160 people
- Sponsor
- Universiteit Antwerpen
Lymphedema
Effects of Complex Decongestive Therapy Applied on Patients With Lower Extremity Lymphedema
The aim of this study is to investigate the effects of complex decongestive therapy applied to patients with lymphedema in the lower extremities on body awareness, functionality and quality of life.
- Trial name
- NCT05239273
- Testing
- Complex Decongestive Therapy, Control
- Volunteers
- 40 people
- Sponsor
- Ankara Yildirim Beyazıt University
Lymphedema of Leg
Establishing Guidelines for Manual Lymphatic Drainage
The purpose of this study is to establish optimal guidelines for Manual Lymphatic Drainage in participants with lower extremity lymphedema.
- Trial name
- MLD (NCT05509062)
- Testing
- Pressure
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- University of Colorado, Denver
Lower Extremity Lymphedema After Gynecologic Cancer Surgery
BMI Stratified Management Based on Meridian-Lymph Axis Theory for Lower Extremity Lymphedema After Gynecologic Cancer Surgery
This study aims to investigate the impact of a BMI-stratified intervention program based on the meridian-lymphatic axis theory on the incidence of lower extremity lymphedema in postoperative patients with gynecological malignant…
- Trial name
- MLA-BMI-LLE (NCT07374835)
- Testing
- Meridian-Lymph Axis Based BMI Stratified Management, Routine Lymphatic Edema Care
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Hong Zhang
Gynecologic Cancer
Randomized Trial of Exercise on Lower Extremity Edema After Lymphadenectomy in Gynecologic Cancer
The primary outcome is the change in lower extremity edema-related symptoms. Secondary outcomes include the compliance rate of management guidelines for lower extremity edema, the performance rate for pelvic and lower extremity…
- Trial name
- NCT01849224
- Testing
- Pelvic and lower extremity exercise
- Where
- South Korea
- Volunteers
- 148 people
- Sponsor
- National Cancer Center, Korea
Lymphedema, Lower Limb Lymphedema
Tissue Elastography Assessement and Cuteous and Cubcutaneous Thickness Measurement Following Manual Lymph Drainage in Legs With Lymphedema
Tissue Elastography Assessement and Cuteous and Cubcutaneous Thickness Measurement Following Manual Lymph Drainage in Legs With Lymphedema Hence the importance of evaluating the impact of an intensive five-day decongestive…
- Trial name
- ELASTOLYMPH (NCT05186142)
- Testing
- Ultrasonography / Ultrasound elastography
- Where
- France
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Primary Lymphedema
Primary Lymphedema and Mutation CELSR1 (Cadherin EGF LAG Seven-pass G-type Receptor 1)
The investigators will describe the expression of mutation CELSR1 with codon stop and amino acids substitution mechanism in primary lymphedema, in both clinical examination and imaging exploration
- Trial name
- CELSR1 (NCT04919655)
- Where
- France
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Lymphedema Lower Extremity
Assessment of the Efficacy of the Dynamic Decongestive System in the Intensive Phase of Lower Limb Lymphedema
The goal of this study is to compare the efficacy of a dynamic compression device (DDS) with traditional multicomponent bandages (TMCB) in terms of excess volume reduction in lower limb lymphoedema during the first 5 days of…
- Trial name
- EDYDES-int (NCT07622615)
- Testing
- Control group: Traditional multicomponent bandages, DDS group: Dynamic compression device (DDS)
- Where
- 3 sites in France, Germany
- Volunteers
- 110 people
- Sponsor
- Jean-Paul Belgrado
Lower Extremity Lymphedema
Feasibility and Effectiveness of Lymphedema Education Program After Gynecological Cancer Surgery
This study aims to examine the effect of lower extremity lymphedema prevention training based on the Symptom Management Model on women undergoing gynecological cancer surgery on lymphedema development, quality of life, and…
- Trial name
- NCT06251856
- Testing
- lymphedema education program
- Volunteers
- 28 people
- Sponsor
- Koç University
Cellulitis, Cellulitis of Arm
Handheld Infrared Thermometer to Evaluate Cellulitis
It can be difficult to differentiate cellulitis from non-infectious mimics, like venous stasis. One way of determining the difference is feeling skin surface temperature.
- Conditions
- Cellulitis, Cellulitis of Arm, Cellulitis of Leg
- Trial name
- HI-TEC (NCT03846635)
- Where
- Canada
- Volunteers
- 52 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre