Clinical trials: Lens Disease
Presbyopia, Refractive Error
Dispensing Study to Assess Visual Performance of Prototype Contact Lenses
The aim of this study is to assess visual performance of prototype soft contact lens designs compared to commercially available contact lenses over one-week of lens wear.
- Trial name
- NCT02214797
- Testing
- Etafilcon A, Lotrafilcon B , Senofilcon A
- Where
- Australia
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Brien Holden Vision
Myopia
Product Performance of a New Silicone Hydrogel Contact Lens
The objective of this study is to evaluate the product performance of kalifilcon A, compared to the Johnson \& Johnson Acuvue Oasys® 1-Day with HydraLuxe™ (senofilcon A) daily disposable contact lens and Alcon DAILIES TOTAL1®…
- Trial name
- NCT04901897
- Testing
- kalifilcon A, delefilcon A, senofilcon A
- Where
- 35 sites in United States
- Volunteers
- 805 people
- Sponsor
- Bausch & Lomb Incorporated
Myopia, Refractive Errors
A Clinical Trial to Evaluate the Vision Correction Safety and Efficacy of MSiHy Silicone Hydrogel Soft Contact Lens
This is a prospective, randomized, double-blind, parallel, active-controlled, multi-center clinical study. The purpose is to evaluate the safety and effectiveness wearing "MSiHy Silicone Hydrogel Soft Contact Lens".
- Trial name
- NCT06716385
- Testing
- MSiHy Silicone Hydrogel Soft Contact Lens, Monthly Silicone Hydrogel Contact Lenses (oA)
- Where
- 3 sites in Taiwan
- Volunteers
- 134 people
- Sponsor
- Visco Vision Inc.
Cataract
Safety and Effectiveness of the Opira AIOL in Comparison to Commercial IOLs in Patients Undergoing Cataract Surgery
This is a clinical trial comparing an investigative accommodative IOL and two commercial IOLs in patients with cataracts undergoing primary cataract surgery.
- Trial name
- NCT04756908
- Testing
- Cataract Surgery
- Where
- 2 sites in Costa Rica, Mexico
- Volunteers
- 200 people
- Sponsor
- FSV6, Ltd.
Cataract
Prospective, Multicenter, Non-comparative Clinical Investigation to Support Safety & Effectiveness of I.SPACE®
I.SPACE® is a hyaluronic acid injectable gel CE (European Conformity) marketed since 2010. It is indicated for use as a surgical aid in ophthalmic anterior segment surgery.
- Trial name
- PROMIR (NCT05146310)
- Testing
- I.SPACE®
- Where
- 3 sites in France
- Volunteers
- 81 people
- Sponsor
- Laboratoires Vivacy
Cataract
Capella Scientia Development Study
This study involves collecting biometry and aberration data using the next generation biometer, Unity DX.
- Trial name
- NCT06987474
- Testing
- Unity DX and SMARTCataract DX (SCDX) Biometer, IOLMaster 700 Biometer, Argos with Alcon Image Guidance Biometer
- Where
- 5 sites in United States, India and 2 more
- Volunteers
- 400 people
- Sponsor
- Alcon Research
Presbyopia
Multifocal High ADD Contact Lens Proof of Concept Trial
The purpose of this study is to evaluate the visual performance of a new multifocal High ADD contact lens compared to the currently-marketed AIR OPTIX® AQUA MULTIFOCAL (AOAMF) High ADD Contact Lens.
- Trial name
- NCT02117544
- Testing
- Lotrafilcon B multifocal contact lenses (new), Lotrafilcon B multifocal contact lenses
- Volunteers
- 268 people
- Sponsor
- Alcon Research
Myopia
Using Contact Lenses and Spectacle Lenses as Myopia Interventions.
Effect of alternating contact lenses and spectacles for myopia control.
- Trial name
- NCT07845721
- Testing
- Test Spectacle Lens & Contact Lens, Control Spectacle Lens & Contact Lens
- Where
- 2 sites in Canada, United Kingdom
- Volunteers
- 58 people
- Sponsor
- CooperVision International Limited (CVIL)
Myopia, Hyperopia
A Clinical Comparison of Proclear® 1 Day Multifocal and Clariti® 1 Day Multifocal 3 Add
The aim of this study is to compare the overall lens satisfaction between two soft multifocal contact lenses.
- Conditions
- Myopia, Hyperopia, Presbyopia
- Trial name
- NCT06869044
- Testing
- omafilcon A lens, Low ADD power somofilcon A lens, Medium ADD power somofilcon A lens
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- CooperVision International Limited (CVIL)
Myopia
Comparing a Monthly Replacement Lens Versus a Daily Disposable Lens
The purpose of this study was to compare subjective ratings of lens handling at insertion for a monthly replacement lens versus a daily disposable lens in habitual soft lens wearers.
- Trial name
- NCT06046209
- Testing
- Control Lens, Test Lens
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- CooperVision, Inc.
Cataract, Phacoemulsification Cataract Surgery
Efficacy and Safety of PRO-155 Versus Nevanac in Post Phacoemulsification
The purpose of this study is to evaluate efficacy and safety of the ophthalmic solution PRO-155 in patients post phacoemulsification.
- Trial name
- NCT01657266
- Testing
- PRO-155, Nevanac
- Where
- Mexico
- Volunteers
- 160 people
- Sponsor
- Laboratorios Sophia S.A de C.V.
Ametropia
Evaluation of Monthly Replacement Lenses in Habitual Soft Contact Lens Wearers Who Report Frequent Digital Devise Use
To evaluate the clinical performance of two monthly silicone hydrogel contact lenses in habitual wearers of frequent replacement (FRP) lenses when worn for 1-month.
- Trial name
- NCT05166902
- Testing
- Lens A (comfilcon A lens), Lens B (lehfilcon A lens)
- Where
- 4 sites in United States, Canada
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Presbyopia
Clinical Validation Study of Comfilcon A Multifocal Toric Contact Lenses
This is a study to evaluate the clinical performance and subjective acceptance of an investigational contact lens (test), compared to a marketed lens (control) in an in-office setting.
- Trial name
- NCT03417557
- Testing
- Comfilcon A lens (test), Omafilcon B lens (control)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- CooperVision, Inc.
Cataract
Clinical Study - ES 900 - 2020-1
EYESTAR 900 is a device developed by Haag-Streit which utilises 3D OCT for quantitative measurements of the geometry of the entire eye, including ocular biometry and corneal topography.
- Trial name
- NCT05304182
- Testing
- EYESTAR 900, LENSTAR LS 900
- Where
- India
- Volunteers
- 50 people
- Sponsor
- Haag-Streit AG
Astigmatism
Clinical Performance of Habitual Hydrogel vs. Silicone Hydrogel Toric Contact Lenses
Evaluate the clinical performance of existing wearers of hydrogel toric lenses when refitted with Avaira toric silicone hydrogel contact lenses over 1 week of wear.
- Trial name
- NCT02142361
- Testing
- enfilcon A
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- CooperVision, Inc.
Ametropia
One-month Clinical Evaluation of Silicone Hydrogel Definitive 65 HPT Contact Lenses
Comparison of different contact lens materials.
- Trial name
- NCT02312323
- Testing
- Definitive 65 HPT contact lenses, Definitive 65 contact lenses
- Where
- 2 sites in Germany
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Contamac Ltd
Cataracts
Safety and Effectiveness of the Calhoun Vision Light Adjustable Intraocular Lens (LAL)
The primary objective of this study is to evaluate, for the visual correction of aphakia, the safety and effectiveness of the Calhoun Vision Light Adjustable intraocular lens (LAL) and Light Delivery Device (LDD) in treating…
- Trial name
- NCT00845520
- Testing
- Lens implantation +1.00 D postop target, Lens implantation -1.00 D postop target, Lens implantation 0.00 D postop target
- Where
- 6 sites in United States, Mexico
- Volunteers
- 74 people
- Sponsor
- Calhoun Vision, Inc.
Cataract
Bioequivalence of Eye Drops and Spray Administration of Vigamox
The study compares the amounts of Vigamox absorbed when administered as eye drops or in a spray form. Both administrations will be prior to patients undergoing elective cataract surgery and the aqueous samples will be analyzed by…
- Trial name
- NCT00666042
- Testing
- Vigamox - administration in spray form, Vigamox eye drops
- Where
- Israel
- Volunteers
- 16 people
- Sponsor
- Advanced Ophthalmic Pharma
Myopia, Progressive
Choroidal Response to Novel Spectacle Lens to Control Myopia Progression
Diurnal variations in the thickness of the choroid have been reported in the literature, and, more recently, the role of the choroid has been studied with respect to its role in myopia (near-sightedness) progression.
- Trial name
- CHERRY (NCT03818880)
- Testing
- Novel spectacle lens design
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- SightGlass Vision, Inc.
Cataract
Night Driving Pilot
Pilot study to evaluate usability of Mesotest II for assessment of night driving capacity of pseudo-phakic patients implanted with aspheric monofocal posterior chamber IOL *AT.Smart 46LC.
- Trial name
- NCT00876278
- Testing
- *AT.Smart 46LC
- Where
- Germany
- Sponsor
- Carl Zeiss Meditec AG
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