Clinical trials: Lens Disease
Cataract, Lens Opacities
Clinical Investigation of a Monofocal Toric Intra Ocular Lens (IOL) in Cataractous Eyes
This is a Multi-center, single-arm and non-masked study whereby patients undergoing routine cataract surgery be implanted with a hydrophobic acrylic monofocal toric intraocular lens PODEYE TORIC (model POD T 49P).
- Conditions
- Cataract, Lens Opacities, Astigmatism
- Trial name
- PHY2107 (NCT05255029)
- Testing
- POD T 49P implantation experimental
- Where
- 4 sites in Japan
- Volunteers
- 42 people
- Sponsor
- Beaver-Visitec International, Inc.
Myopia, Refractive Error
A Comparison of Two Color Contact Lenses in Habitual Clear Contact Lens Wearers
The purpose of this study was to evaluate overall satisfaction with AIR OPTIX® COLORS as compared to FRESHLOOK® COLORBLENDS contact lenses.
- Trial name
- NCT01782482
- Testing
- Lotrafilcon B contact lens with color, Phemfilcon A contact lens with color
- Volunteers
- 574 people
- Sponsor
- Alcon Research
Myopia
LSH Silicone Hydrogel Soft Hydrophilic Contact Lens for Daily Wear
This study is to evaluate the performance of the LSH (mangofilcon A) silicone hydrogel soft contact lenses when used as a daily wear contact lens for the correction of myopia.
- Trial name
- NCT01735045
- Testing
- Lagado LSH (mangofilcon A) Soft (hydrophilic) Contact Lens, Benz 3GX (hioxifilcon B) Soft (hydrophilic) Contact Lens
- Where
- 5 sites in United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Szabocsik and Associates, Inc.
Cataract
Vision Performance Evaluation of TECNIS EYHANCE™ With TECNIS SIMPLICITY™ Compared to TECNIS® 1-piece Intraocular Lenses
This study is a 6-month, prospective, multicenter, bilateral, randomized subject- and evaluator-masked, clinical investigation of the TECNIS Eyhance IOL versus the TECNIS 1-piece IOL.
- Trial name
- NCT05025345
- Testing
- Tecnis Eyhance, Tecnis 1 piece IOL
- Where
- 15 sites in United States
- Volunteers
- 228 people
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
Myopia
Comparison of Two Daily Disposable Contact Lenses Over 1-week of Wear
This is a one week 2x2 crossover study comparing delefilcon A with etafilcon A, with a primary hypothesis of comparing the handling of each lens.
- Trial name
- NCT01669629
- Testing
- delefilcon A, etafilcon A
- Where
- 10 sites in United States
- Volunteers
- 183 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Cataract
Combined EDOF / Trifocal
The purpose of this study is to obtain postoperative visual performance data of patients with bilateral implantation of the AT LARA IOL or the AT LARA implanted in the dominant eye and AT LISA tri implanted in the other eye.
- Trial name
- NCT05462067
- Testing
- AT LARA IOL, AT LISA Tri IOL
- Where
- 4 sites in Denmark, Germany and 1 more
- Volunteers
- 72 people
- Sponsor
- Carl Zeiss Meditec AG
Cataracts
Comparison of Centurion® Vision System With Balanced Tip and the Infiniti® Vision System With the Mini Flared Kelman (MFK) Tip During Cataract Extraction Surgery of Hard Lenses
The purpose of this study is to demonstrate that the Centurion® Vision System (CVS) used with the 45° Balanced Tip will result in less Cumulative Dissipated Energy (CDE) than the lnfiniti® Vision System (IVS) used with the 45°…
- Trial name
- NCT02502526
- Testing
- Centurion® Vision System, 45° Balanced Tip, Centurion® Vision System, 45° MFK Tip, lnfiniti® Vision System, 45° MFK Tip
- Volunteers
- 231 people
- Sponsor
- Alcon Research
Aphakia, Presbyopia
Real-World Study of Vivity Intraocular Lenses (IOLs)
The primary objective of this clinical study is to assess the clinical performance of the AcrySof IQ Vivity Extended Vision IOL in a Chinese population.
- Trial name
- NCT04800016
- Testing
- AcrySof IQ Vivity Extended Vision IOL, Cataract surgery
- Where
- China
- Sponsor
- Alcon Research
Cataract, Presbyopia
Retrospective / Prospective Clinical Study of AcrySof® IQ ReSTOR® +2.5 D Multifocal Toric Intraocular Lenses
The purpose of this study is to characterize the safety and effectiveness of the ACRYSOF IQ ReSTOR +2.5 diopter (D) Multifocal Toric Intraocular Lens (IOL) in subjects at least 3 months and no more than 14 months after IOL…
- Conditions
- Cataract, Presbyopia, Corneal Astigmatism
- Trial name
- NCT02176343
- Testing
- AcrySof® IQ ReSTOR® +2.5 D Multifocal Toric IOL
- Volunteers
- 37 people
- Sponsor
- Alcon Research
Cataract
Aqueous Concentrations and PGE2 Inhibition of Ketorolac 0.4% vs. Bromfenac 0.09% in Cataract Patients: Trough Drug Effects
The purpose of this study is to compare the ability of two different topical NSAIDs (non-steroidal anti-inflammatory medications used for pain relief) to reach the back of the eye and to stop inflammation.
- Trial name
- NCT00469690
- Testing
- Acular, Xibrom
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Innovative Medical
Myopia
Evaluation of The Comfort of Orthokeratology Lenses Fit Using A New Software
As new orthokeratology fitting software emerges onto the market, it is of interest to assess their usefulness in guiding eye practitioners with lens fit.
- Trial name
- NCT05389072
- Testing
- control contact lens
- Where
- 4 sites in United States, Spain
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- CooperVision International Limited (CVIL)
Myopia
Evaluation of The Clinical Acceptance of Soft Contact Lenses for Myopia Control
The main objective of the study was to evaluate the clinical acceptance of soft contact lenses for Myopia control.
- Trial name
- NCT04709237
- Testing
- omafilcon A control lens, omafilcon A test lens 1, omafilcon A test lens 2
- Where
- United Kingdom
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia
Comparative Performance of PureVision, Acuvue Oasys and O2Optix
The objective of this study is to evaluate the performance of the PureVision Contact Lens compared to Acuvue Oasys Contact lens and O2Optix Contact lens when worn on a daily wear basis.
- Trial name
- NCT00640341
- Testing
- PureVision Contact Lens, Acuvue Oasys Contact Lens, O2Optix Contact lens
- Where
- United States
- Volunteers
- 510 people
- Sponsor
- Bausch & Lomb Incorporated
Aphakia, Cataract
Visual Quality Following Aspheric Intraocular Lens (IOL) Implantation - a Comparative Clinical Study
To evaluate visual acuity and quality of vision in participants undergoing cataract surgery with a Hoya model 751 intra-ocular lens and to compare the visual results to the common monofocal lens in use.
- Trial name
- 751 (NCT01544777)
- Testing
- Study IOL, Hoya iSert 751, Negatively aspheric IOL
- Where
- Australia
- Volunteers
- 42 people
- Sponsor
- Hoya Surgical Optics, Inc.
Cataract
Chloroprocaine 3% Gel Eye Drop as Topical Anestheticsin Phacoemulsification.
Randomized clinical trial, multicenter, two-armed, to investigate and compare the clinical efficacy of chloroprocaine 3% gel and tetracaine 0.5% eye drop as topical anestheticsin phacoemulsification.
- Trial name
- NCT04685538
- Testing
- Chloroprocaine 3%, Tetracaine 0.5%
- Where
- 27 sites in Italy, Slovakia and 1 more
- Volunteers
- 338 people
- Sponsor
- Sintetica SA
Refractive Errors, Myopia
Clinical Performance Assessment of Two Silicone Hydrogel Daily Disposable Contact Lenses
The purpose of this study is to assess the overall clinical performance of a contact lens made with a modified manufacturing process.
- Trial name
- NCT05725317
- Testing
- LID220365 contact lens, LID006961 contact lens
- Where
- 7 sites in United States
- Volunteers
- 114 people
- Sponsor
- Alcon Research
Dry Eye
A Clinical Evaluation Pilot Study of the Efficacy of Blink® Tears Lubricant Eye Drops for the Relief of Dry Eye Symptoms Following Implantation of Tecnis® Multifocal Introcular Lens
To evaluate the safety and efficacy of BLINK™ tears compared with NO topical artificial tear use in improving subject's visual performance and reduce ocular symptoms of discomfort in subjects who have undergone cataract surgery…
- Trial name
- NCT01061268
- Testing
- No topical artificial tear, Blink® Tears Lubricant Eye Drops
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Innovative Medical
Cataract
Clinical Investigation of the Next-Generation Intraocular Lens
This study is a 6-month, prospective, multicenter, bilateral, randomized clinical investigation of the TECNIS Model ZHR00 and Model ZQR00 IOLs versus the TECNIS Symfony control IOL.
- Trial name
- NCT03111550
- Testing
- Investigational Intraocular Lens Device #1: TECNIS Model ZHR00, Investigational Intraocular Lens Device #2: TECNIS Model ZQR00, TECNIS Symfony® Extended Range of Vision Intraocular Lens: Model ZXR00
- Where
- 12 sites in United States
- Volunteers
- 242 people
- Sponsor
- Abbott Medical Optics
Dry Eye
Evaluation of Onefit Scleral Lenses in the Mangement of Dry Eye
This study is being conducted to determine if scleral lenses treated with Hydra-PEG improve comfort and dryness.
- Trial name
- NCT05973409
- Testing
- scleral lens
- Where
- Canada
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- CooperVision International Limited (CVIL)
Cataract
A Comparison of Visual Function After Bilateral Implantation of Presbyopia-Correcting Intraocular Lenses (IOLs)
The purpose of this study is to evaluate visual and refractive parameters in a series of subjects bilaterally implanted with presbyopia-correcting intraocular lenses (IOLs) during cataract surgery.
- Trial name
- NCT01257217
- Testing
- AcrySof® IQ ReSTOR® +3.0 D Multifocal IOL Model SN6AD1, AcrySof® IQ ReSTOR® +3.0 D Multifocal Toric IOL Model SND1TT, Acri.LISA® 366D IOL
- Volunteers
- 31 people
- Sponsor
- Alcon Research
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