Clinical trials: Lens Disease
Astigmatism
Clinical Evaluation of Two Toric Contact Lenses in Current Non-toric Lens Users
The purpose of this study is to evaluate the clinical performance, defined as successful fit, of two toric contact lenses (one daily disposable and the other daily wear reusable contact lens to correct astigmatism) in current…
- Trial name
- NCT01180998
- Testing
- Senofilcon A Toric (AOfA), Etafilcon A Toric (1DAMfA)
- Where
- 18 sites in United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Cerebrotendinous Xanthomatosis (CTX)
Cerebrotendinous Xanthomatosis (CTX) Prevalence Study
Iiopathic bilateral cataracts occur in many children with Cerebrotendinous Xanthomatosis (CTX) so the opportunity to use contact with health care providers in connection with pediatric cataract evaluation and treatment is a…
- Trial name
- NCT02638220
- Where
- 44 sites in United States
- Volunteers
- 442 people
- Sponsor
- Travere Therapeutics, Inc.
Refractive Errors
Three Daily Wear Monthly Replacement Silicone Hydrogel Contact Lenses With Two Multi-purpose Disinfecting Solution Combinations
The purpose of this study is to evaluate corneal staining observed after 2 hours of wear with an investigational contact lens against both PureVision contact lenses pre-cycled with Biotrue and Biofinity contact lenses pre-cycled…
- Trial name
- NCT04789382
- Testing
- LID018869+RepleniSH, LID018869+Biotrue, Biofinity+RepleniSH
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Alcon Research
Myopia, Progressive
Myopia Control Combined PBM With Myopic Defocus Lens in Children
To study the efficacy of myopi control with two methods: low lever red light and peripheral defocus spectacles with four groups and design with prospective, double-blind, randimized, and with control for 6 month.
- Trial name
- NCT05756959
- Testing
- PBM, Peripheral defocus spectacles, Single vision spectacles
- Where
- China
- Volunteers
- 304 people
- Sponsor
- Beijing Airdoc Technology Co., Ltd.
Cataract
Clinical Investigation of the Modified Rayner Monofocal Aspheric 600C (With Axis Marks) Intraocular Lens
This will be a prospective, open-label, 125 subject (maximum), two-year multicentre investigation to assess the safety, effectiveness and rotational stability of the modified 600C (axis marks) intraocular lens (IOL) in subjects…
- Trial name
- NCT02378636
- Testing
- 600S
- Where
- United Kingdom
- Sponsor
- Rayner Intraocular Lenses Limited
Cataract
A Single-arm, Open-label Feasibility Study for Assessing the Safety and Performance of the Modified AssiAnchor
The AssiAnchor 2 is a fixation ophthalmic device. The device is manufactured by Hanita Lenses from PMMA material which is being used for the production of Intra-ocular lenses.
- Trial name
- cataracts (NCT03455114)
- Testing
- AssiAnchor
- Where
- Israel
- Volunteers
- 10 people
- Sponsor
- Hanita Lenses
Cataract
Clinical Outcome at 5 Years After Implantation of the Liberty677MY Multifocal Intraocular Lens
The study will assess visual outcomes, light disturbances and patients' satisfaction after implantation with the Liberty677MY multifocal IOL, as well as protection of PCO development within 5 year follow-up.
- Trial name
- NCT04220255
- Testing
- Liberty677MY Multifocal IOL
- Where
- Hungary
- Volunteers
- 50 people
- Sponsor
- Medicontur Medical Engineering Ltd
Cataract, Lens Opacities
Comparison of Clinical Outcomes on Trifocal IOLs FineVision POD F GF and FineVision POD F in Asian Eyes
Prospective, randomised, controlled, single-surgeon, single-center clinical study to compare the clinical outcomes of two trifocal IOLs with different material (hydrophobic and hydrophilic) from the same manufacturer.
- Conditions
- Cataract, Lens Opacities, Presbyopia
- Trial name
- PHY1706 (NCT03306355)
- Testing
- IOL implantation experimental, IOL implantation active comparator
- Where
- Philippines
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Beaver-Visitec International, Inc.
Cataracts
Comparison of Corneal Aberrations and Visual Outcomes in AcrySof IQ Toric Patients Versus Limbal Relaxing Incision (LRI) Patients
A prospective evaluation of postoperative corneal aberrations and visual parameters in patients assigned to either an AcrySof IQ Toric intraocular lens (IOL) group or a group implanted with a SN60WF IOL and having concomitant…
- Trial name
- NCT00929747
- Testing
- Toric, Limbal Relaxing Incision
- Where
- United States
- Sponsor
- Alcon Research
Cataracts
A Real-World Study for the TECNIS Synergy™ Intraocular Lens
This is a prospective and retrospective, single-center, single-arm, open-label clinical study of the TECNIS Synergy™ IOL. The study will enroll up to 100 subjects from a single site in China.
- Trial name
- NCT05090826
- Testing
- Model ZFR00V
- Where
- China
- Volunteers
- 42 people
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
Bilateral Cataract
Pilot Study With a Diffractive Trifocal IOL (POD AY 26P FineVision)
The principal objective of the study is to determine the visual acuity at far, intermediate and near distances tested with optotypes at different distances from the eyes and tested with defocus addition lenses of patients…
- Trial name
- NCT02042755
- Testing
- trifocal intraocular lens
- Where
- Israel
- Volunteers
- 19 people
- Sponsor
- Beaver-Visitec International, Inc.
Inflammation, Cataract
Safety and Tolerability of PRO-155 Ophthalmic Solution 0.09% in Healthy Volunteers.
Study to evaluate the safety and tolerability of PRO-155 Ophthalmic Solution 0.09 % in healthy volunteers.
- Trial name
- PRO-155 (NCT01535443)
- Testing
- Bromfenac
- Where
- Mexico
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Laboratorios Sophia S.A de C.V.
Myopia, Hyperopia
Clinical Evaluation of Two Frequent Replacement Soft Spherical Contact Lenses
This was a single-blind (participant masked), interventional, prospective, direct refit, bilateral wear short-term fitting study.
- Trial name
- NCT05656885
- Testing
- Lens A, Lens B
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia, Astigmatism
Safety and Efficacy Evaluation of a New Contact Lens Disinfecting Solution in Soft Contact Lens Wearers
The purpose of this study is demonstrate substantial equivalence of an investigational contact lens disinfecting solution to a commercially available contact lens solution in silicone hydrogel and soft contact lens wearers.
- Conditions
- Myopia, Astigmatism, Hyperopia, Refractive Error
- Trial name
- NCT01912768
- Testing
- FID 120947A contact lens disinfecting solution, renu fresh multi-purpose solution, Soft contact lenses
- Volunteers
- 362 people
- Sponsor
- Alcon Research
Cataract
Nevanac 3-Month Safety Study With QID Dosing
The purpose of this study is to determine the safety of Nevanac 0.1% compared to Acular LS 0.4% and Vehicle in patients treated before cataract surgery and for approximately 90 days following surgery.
- Trial name
- NCT00332774
- Testing
- Nepafenac ophthalmic solution 0.1%, Ketorolac Tromethamine ophthalmic solution 0.4%, Nepafenac ophthalmic suspension vehicle
- Where
- United States
- Volunteers
- 149 people
- Sponsor
- Alcon Research
Cataract
Mapracorat Ophthalmic Suspension for the Treatment of Ocular Inflammation Following Cataract Surgery
The objective of this clinical study is to compare the safety and efficacy of Mapracorat Ophthalmic Suspension, 3% to vehicle for the treatment of postoperative inflammation and pain following cataract surgery.
- Trial name
- NCT01230125
- Testing
- Mapracorat, Vehicle
- Where
- United States
- Volunteers
- 311 people
- Sponsor
- Bausch & Lomb Incorporated
Astigmatism
Dispensing Evaluation of New Daily Disposable Toric Soft Contact Lens.
The purpose of this study is to determine the relative performance of a new daily disposable toric soft contact lens against a daily disposable toric contact lens currently available in market, specifically with regards to the…
- Trial name
- NCT01055132
- Testing
- Etafilcon A toric contact lens, Nelfilcon A toric contact lens
- Where
- 6 sites in United States
- Volunteers
- 70 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Cataract
A Clinical Study Comparing Postoperative Outcomes Between the TECNIS Intraocular Lens.
This is a prospective, multi-center, masked, three-arm, randomized clinical study of the TECNIS Eyhance Toric II IOL (test #1) and TECNIS Synergy Toric II (test #2) compared to the TECNIS Toric 1-Piece IOL (control).
- Trial name
- NCT05396599
- Testing
- Model DIU, Model DFW, Model ZCT
- Where
- 5 sites in United States
- Volunteers
- 35 people
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
Cataract
Safety and Effectiveness of a Multifocal Intraocular Lens (IOL)
To evaluate the safety and effectiveness of the ZM900 Tecnis Multifocal lens. Results from two studies (an original study with 125 multifocal and 123 monofocal subjects, protocol DIOL-101-TCNS, and an expansion study with 222…
- Trial name
- NCT00747565
- Testing
- Tecnis ZM900 Multifocal Intraocular Lens, CeeOn 911A monofocal IOL
- Volunteers
- 470 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Cataract, Pseudophakia
Retrospective, Non-interventional, Comparative Clinical Investigation of the Safety and Performance of 690AD and 690ADY Monofocal Intraocular Lens Implantation With Extended Patient Enrolment
Medicontur hydrophilic posterior chamber monofocal intraocular lens (IOLs) are indicated to improve vision at far distance in adults with cataract and/or ametropia (hyperopia, myopia), secondarily to removal of the crystalline…
- Conditions
- Cataract, Pseudophakia, Intraocular Lens Complication, Intraocular Lens Opacification
- Trial name
- NCT06578923
- Testing
- Standard of care, Patient satisfaction questionnare
- Where
- 2 sites in Hungary
- Volunteers
- 51 people
- Sponsor
- Medicontur Medical Engineering Ltd
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