Clinical trials: Lens Disease
Astigmatism
Evaluation of Orientation and Visual Acuity of Four Toric Soft Contact Lenses When Head is Tilted at 90 Degrees
The purpose of this study is to determine the relative performance of a new toric soft contact lens against three toric contact lens currently available in market, specifically with orientation and visual acuity when head is…
- Trial name
- NCT00583908
- Testing
- senofilcon A, balafilcon A toric, lotrafilcon B toric
- Where
- United Kingdom
- Volunteers
- 14 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia
A Comparison of Two Daily Disposable Contact Lenses
This study seeks to evaluate the clinical performance of a recently improved daily disposable contact lens to an established daily disposable contact lens that contains a wetting agent.
- Trial name
- NCT00600080
- Testing
- etafilcon A, nelfilcon A
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Astigmatism
Performance of Two Toric Silicone Hydrogel Contact Lenses
Prospective study to evaluate the clinical performance of fanfilcon A toric contact lens and senofilcon A toric contact lens after two weeks of wear.
- Trial name
- NCT03578926
- Testing
- fanfilcon A toric lens, senofilcon A toric lens
- Where
- Mexico
- Volunteers
- 45 people
- Sponsor
- CooperVision, Inc.
Myopia
Dehydration of Stenfilcon A Contact Lenses Versus Delefilcon A Contact Lenses
The study will explore in vivo lens dehydration rates across a 12hr wear period for the study lenses.
- Trial name
- NCT02366923
- Testing
- stenfilcon A, delefilcon A
- Where
- Canada
- Volunteers
- 28 people
- Sponsor
- CooperVision, Inc.
Cataract, Lens Opacities
PMCF Study on Monofocal Toric IOL (PODEYE TORIC) in Spain
This is a multicentric, prospective, open-label PMCF study whereby patients undergoing routine cataract surgery will have mono- or bilateral implantation of hydrophobic acrylic monofocal toric intraocular lens PODEYE TORIC (study…
- Conditions
- Cataract, Lens Opacities, Astigmatism
- Trial name
- PHY2103 (NCT04866719)
- Testing
- IOL implantation experimental
- Where
- 5 sites in Spain
- Volunteers
- 76 people
- Sponsor
- Beaver-Visitec International, Inc.
Myopia
To Evaluate The Performance Of Two Monthly Replacement Silicone Hydrogel Contact Lenses After 1-month Of Wear
To evaluate the performance of two monthly replacement silicone hydrogel contact lenses in habitual FRP CL wearers when worn for 1-month.
- Trial name
- NCT05333965
- Testing
- Lens A (lehfilcon A lens), Lens B (comfilcon A lens)
- Where
- Canada
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Cataract
Evaluation of the BunnyLens TR Intraocular Lens
With age, a human crystalline lens opacifies (cataract) disabling the eye in generating a clear, well contrasted image. The only therapeutic solution to this problem is surgical replacement of the crystalline lens with an…
- Trial name
- NCT01659801
- Testing
- BunnyLens TR
- Volunteers
- 25 people
- Sponsor
- Hanita Lenses
Cataract
Safety of NGOIS Compared to BSS Plus in Pediatric Patients
To evaluate the Safety of Next Generation Ophthalmic Irrigating Solution compared to BSS Plus for use during cataract surgery in Pediatric patients.
- Trial name
- NCT00346528
- Testing
- Next Generation Ophthalmic Irrigating Solution (NGOIS), BSS Plus
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Alcon Research
Eye Dryness
Comparison of Two Marketed Lenses in a Controlled Environment
This study is comparing two silicone hydrogel contact lenses in a controlled environment for identification of characteristics associated to vision.
- Trial name
- NCT02212301
- Testing
- senofilcon A, lotrafilcon B
- Where
- United Kingdom
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Cataract
Femtosecond Laser for Cataract Surgery
The objective of this study is to evaluate the safety and efficacy the OptiMedica Femtosecond Laser System, also known as the Catalys™ Precision Laser System, to perform two surgical maneuvers used in the treatment of subjects…
- Trial name
- NCT02110212
- Testing
- U/S Surgery and CCC, FS Laser Surgery
- Volunteers
- 17 people
- Sponsor
- Abbott Medical Optics
Cataract
Addressing of Efficacy and Safety of Femtosecond-laser Assisted Versus Manual Lens Fragmentation Procedure
This clinical study is a randomized, controlled, open, prospective, multi-centre, multi-surgeon post-market-clinical-follow-up study to investigate the impact of cataract grade on the efficacy and safety of femtosecond laser…
- Trial name
- NCT01971177
- Testing
- Femtosecond laser cataract surgery, Manual cataract surgery
- Where
- 2 sites in Czechia, India
- Volunteers
- 136 people
- Sponsor
- Technolas Perfect Vision GmbH
Myopia
Clinical Comparison of Two Daily Disposable Contact Lenses in a Population of Daily Disposable Contact Lens Wearers
The purpose of this study is to evaluate the performance of two commercially marketed daily disposable contact lenses in a population of daily disposable contact lens wearers.
- Trial name
- NCT01233076
- Testing
- Nelfilcon A contact lens, Narafilcon B contact lens
- Volunteers
- 60 people
- Sponsor
- CIBA VISION
Cataract
A Study to Evaluate Real World Outcomes of the enVista® Aspire (EA) and Aspire Toric (ETA) Intraocular Lens in Subjects Undergoing Cataract Extraction
A study to evaluate the real-world clinical performance of the enVista Aspire and Aspire Toric intraocular lens (IOL) models EA and ETA and to assess surgeon and subject satisfaction
- Trial name
- NCT06594185
- Testing
- enVista Aspire EA or Aspire Toric ETA IOLs
- Where
- 62 sites in United States
- Volunteers
- 335 people
- Sponsor
- Bausch & Lomb Incorporated
Cataract, Glaucoma
Evaluation of the Safety and Efficacy of the Bimatoprost Implant System Used in Combination With the SpyGlass IOL Compared to Timolol Ophthalmic Solution (Rhine)
This trial is a randomized study to evaluate the Bimatoprost Implant System used in combination with the SpyGlass IOL to Timolol Ophthalmic Solution in participants with mild to moderate open-angle glaucoma or ocular hypertension…
- Conditions
- Cataract, Glaucoma, Ocular Hypertension
- Trial name
- NCT07218783
- Testing
- Bimatoprost Implant System, SpyGlass IOL, Timolol Maleate Ophthalmic Solution, 0.5%
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- SpyGlass Pharma, Inc.
Myopia
Clinical Evaluation of the Safety and Efficacy of Yung Sheng 38% Color Contact Lens
This was a single group, open-label clinical study to assess the safety and efficacy of Yung Sheng 38% color contact lens for vision correction.
- Trial name
- NCT06128473
- Testing
- Soft Contact Lens
- Volunteers
- 71 people
- Sponsor
- Yung Sheng Optical Co., Ltd.
Cataract, Presbyopia
Comparative Analysis of the Visual Performance and Patient Satisfaction After Cataract Surgery With Implantation of a Medicontur Monofocal (877PAY) or a Medicontur Extended Depth of Focus (877PEY) IOL
The purpose of this multi-center, prospective, randomized, comparative clinical investigation was to evaluate and compare the visual performance at far, intermediate and near distances, the presence of photopic phenomena and…
- Conditions
- Cataract, Presbyopia, Ametropia
- Trial name
- NCT06642779
- Testing
- VFQ- 25 (Visual Function Questionnaire), Optical Biometry, Slit lamps / Fundoscopy / Biomicroscopy
- Where
- 3 sites in Hungary
- Volunteers
- 64 people
- Sponsor
- Medicontur Medical Engineering Ltd
Cataract, Dry Eye
Efficacy of Topical Cyclosporine Versus Tears for Improving Visual Outcomes Following Multifocal IOL Implantation
The purpose of this study is to evaluate the efficacy on quality of vision and dry eye signs and symptoms in patients undergoing cataract surgery using the ReZoom® multifocal IOL.
- Trial name
- NCT00349583
- Testing
- Topical Cyclosporine, Tears
- Where
- United States
- Sponsor
- Innovative Medical
Myopia
Evaluation of the CooperVision, Inc. Fanfilcon A and Enfilcon A Daily Wear Contact Lenses When Used for Frequent Replacement for up to One (1) Month of Daily Wear
This study is a masked, multi-center, daily wear, monthly replacement, bilateral, randomized, lens blocked (subjects remain in the same lens brand throughout the study) concurrent control study enrolling up to 90 subjects with a…
- Trial name
- NCT02555722
- Testing
- fanfilcon A (test), enfilcon A (control)
- Where
- 6 sites in United States
- Volunteers
- 92 people
- Sponsor
- CooperVision, Inc.
Cataract Extraction
Hydrophilic Acrylic Intraocular Lens
The purpose of this study is to evaluate the safety and efficacy of Hydrophilic Acrylic Intraocular Lens after cataract surgery
- Trial name
- NCT00708331
- Testing
- 2 HEMA Hydrophilic Acrylic Intraocular Lens
- Where
- 9 sites in United States
- Sponsor
- EyeKon Medical, Inc.
Dry Eye
Clinical Evaluation of a Multidose Preservative-free Lubricating Eye Drops Contained in Novelia® Eye Dropper in Non-Contact Lens Wearing Patients
This is a 30-Day, multi-site, single-masked, bilateral, active- controlled, 2-Arm parallel group study to evaluate the safety and efficacy of an Investigational product.
- Trial name
- NCT05661851
- Testing
- Investigational Lubricating Eye Drop in a Novelia® bottle, Blink® Tears eye Drops
- Where
- 8 sites in United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
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