Clinical trials: Lens Disease
Refractive Error
Evaluation of Vision Effects of a Cosmetic Tinted Hydrogel Contact Lens
Subjects will wear 2 of 2 study contact lenses for a wearing time of approximately three to four hours at each of the visits in order to take measurements on binocular functional visual performance.
- Trial name
- NCT02886923
- Testing
- Hioxifilcon A Test, Hioxifilcon A With Cosmetic Ring Control
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Cataract, Corneal Astigmatism
Evaluation of the Rotational Stability of the Tecnis Toric II IOL
This is a prospective, multicenter, single-arm, open-label clinical study of the commercially available TECNIS Toric II IOL. The study will be conducted in up to 192 subjects needing unilateral or bilateral cataract surgery in up…
- Trial name
- STEELE (NCT04327518)
- Testing
- TECNIS® Toric II
- Where
- 7 sites in United States
- Volunteers
- 125 people
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
Myopia
Comparison of New Contact Lens With Current Marketed Lens
The purpose of this study is to validate the clinical performance of a new contact lens design.
- Trial name
- NCT03360110
- Testing
- Phoebe test lens, stenfilcon A lens (control)
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- CooperVision, Inc.
Cataract
Evaluation of the EpiGlare Tester for the Measurement of Glare-Induced Changes in BSCVA in Subjects With and Without Cataracts
The EpiGlare Tester will identify visual disability resulting from the glare experienced by subjects with cataracts in the glare-induced change in best spectacle corrected visual acuity (BSCVA).
- Trial name
- NCT04739397
- Testing
- Glare Testing
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Epico, LLC
Myopia, Hyperopia
A Bilateral Dispensing Clinical Trial of Sapphire Lens Against Senofilcon A Lens Over 2 Weeks
To evaluate the clinical performance of an investigational silicone-hydrogel lens when worn on a daily wear modality over two weeks of lens wear.
- Trial name
- NCT02345811
- Testing
- Sapphire, senofilcon A
- Where
- 2 sites in United States, Canada
- Volunteers
- 34 people
- Sponsor
- CooperVision, Inc.
Cancer, Cataract
Evaluation of New or Worsening Lens Opacifications in Men With Non-metastatic Prostate Cancer Receiving Denosumab for Bone Loss
This is a phase 3, randomized, double-blind, placebo-controlled study to evaluate new or worsening lens opacifications in men with non-metastatic prostate cancer receiving denosumab for bone loss due to androgen deprivation…
- Conditions
- Cancer, Cataract, Low Bone Mineral Density, Osteopenia
- Trial name
- NCT00925600
- Testing
- Denosumab
- Where
- 172 sites in United States, Australia and 16 more
- Volunteers
- 769 people
- Sponsor
- Amgen
Cataract
Clinical Investigation of AcrySof® IQ PanOptix™ IOL Model TFNT00
The purpose of this clinical study is to compare the visual outcomes of the AcrySof IQ PanOptix Multifocal Intraocular Lens (IOL) Model TFNT00 against that of a monofocal lens, the AcrySof Monofocal IOL Model SN60AT, in order to…
- Trial name
- NCT03280108
- Testing
- AcrySof IQ PanOptix Multifocal IOL, AcrySof Monofocal IOL
- Where
- 12 sites in United States
- Volunteers
- 250 people
- Sponsor
- Alcon Research
Refractive Errors
Clinical Assessment of a Daily Disposable Soft Silicone Hydrogel Contact Lens
The purpose of this study is to assess the clinical performance of DAILIES TOTAL1® spherical soft contact lenses over approximately 1 week of daily wear.
- Trial name
- NCT06044948
- Testing
- Delefilcon A contact lenses
- Where
- 6 sites in United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Presbyopia
Comparing the Performance of 1 Day Multifocal Contact Lenses
The objective of the study was to compare the lens handling and performance of Lens A to habitually worn multifocal contact lenses and to the competitor Lens B.
- Trial name
- NCT04449263
- Testing
- Lens A, Lens B, Habitual Lenses
- Where
- 5 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Cataract Senile
Precisight® Intraocular Lens Implantation for Cataract Treatment
The purpose of this study is to determine the refractive outcomes and optimize the clinical features of a new intraocular lens intended to treat the senile cataract.
- Trial name
- PEACE (NCT02970487)
- Testing
- Intraocular implant of the Precisight
- Where
- Philippines
- Volunteers
- 96 people
- Sponsor
- InfiniteVision Optics
Presbyopia, Refractive Errors
Prospective Multicenter Clinical Study on the Visual and Refractive Outcomes and Safety Outcomes Following Implantation of an AddOn Intraocular Lens in Previously Pseudophakic Eyes
The purpose of this prospective multicenter clinical study is to evaluate the visual and refractive outcomes and safety outcomes following bilateral implantation of trifocal and/or trifocal toric 1stQ AddOn (Medicontur)…
- Conditions
- Presbyopia, Refractive Errors, Residual Astigmatism
- Trial name
- NCT05596682
- Testing
- supplementary intraocular lenses
- Where
- 4 sites in Belgium, France and 2 more
- Volunteers
- 75 people
- Sponsor
- Medicontur Medical Engineering Ltd
Cataract
The Clareon PanOptix Trifocal IOL: Visual Outcomes and Patient Satisfaction
This will be a single arm, open-label, prospective study of patient-reported outcomes of patients with bilateral implantation of the Panoptix or Panoptix Toric implant.
- Trial name
- NCT05346172
- Testing
- PanOptix or PanOptix Toric IOL
- Where
- 3 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Research Insight LLC
Refractive Error, Myopia
Clinical Comparison of DDT2 Contact Lens and a Daily Disposable Contact Lens - Study 1
The purpose of this study was to evaluate visual acuity at distance when wearing DDT2 contact lenses compared to Acuvue Moist contact lenses.
- Trial name
- NCT03888469
- Testing
- Verofilcon A contact lenses, Etafilcon A contact lenses
- Where
- 5 sites in United States
- Volunteers
- 92 people
- Sponsor
- Alcon Research
Myopia
Fitting Evaluation of Hydrogel and Silicone Hydrogel Sphere Design Contact Lenses
The aim of this non-dispensing fitting study is to evaluate the short term lens fit, vision performance of three monthly replacement sphere lenses.
- Trial name
- NCT03098745
- Testing
- Omafilcon A, Somofilcon A, Omafilcon A - Proclear (PC)
- Where
- Mexico
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Cataracts, Inflammation
Difluprednate Pediatric Study for the Treatment of Inflammation Post-Cataract Surgery
The primary objective of this study was to compare the safety and efficacy of Durezol™ compared to Pred Forte™ for the treatment of inflammation following cataract surgery in a pediatric population 0 to 3 years of age.
- Trial name
- NCT01124045
- Testing
- Difluprednate ophthalmic emulsion, 0.05%, Prednisolone acetate ophthalmic suspension, 1.0%
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Alcon Research
Wrinkle, Rosacea
Evaluation of Cutera Excel V™ Laser With Green Genesis and Micro-Lens Array (MLA)Attachment
Evaluate the Cutera excel V™ Laser with Green Genesis and a Micro-Lens Array (MLA) Attachment
- Conditions
- Wrinkle, Rosacea, Scarring
- Trial name
- NCT03424304
- Testing
- Excel V™ Laser With Green Genesis
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cutera Inc.
Cataract, Inflammation
Indomethacin Eyedrops Compared With Ketorolac Eyedrops for Ocular Inflammation Following Cataract Surgery
This study is being conducted to show that indomethacin is at least as effective as ketorolac for the prevention of ocular inflammation following cataract surgery.
- Trial name
- NCT00904904
- Testing
- Indomethacin ophthalmic solution, Ketorolac Ophthalmic Solution
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- Bausch & Lomb Incorporated
Glaucoma, Ocular Hypertension
Intraocular Pressure Measured by a Novel Sensing Contact Lens Versus Tonometry
While elevated intraocular pressure (IOP) is no longer part of the definition of glaucoma it remains the sole proven modifiable risk factor for the onset and progression of glaucoma.
- Trial name
- NCT04024293
- Testing
- Goldfish (GF)
- Where
- Switzerland
- Volunteers
- 12 people
- Sponsor
- Sensimed AG
Aphakia, Cataract
Comparison of Aspheric Toric & Non-toric Aphakic Intraocular Lenses
The purpose of this multi-center clinical trial is to determine the safety and efficacy of the HSO Toric IOLs for the correction of aphakia and reduction of pre-existing refractive astigmatism.
- Trial name
- COAST (NCT01268540)
- Testing
- FY-60AD, NHT15, NHT30, & NHT53
- Where
- 6 sites in United States
- Volunteers
- 235 people
- Sponsor
- Hoya Surgical Optics, Inc.
Cataract
Evaluate the Safety of DEXYCU for the Treatment of Inflammation Following Ocular Surgery for Childhood Cataract
A Phase 3/4, Prospective, Randomized, Active Treatment-Controlled, Parallel-Design, Multicenter Study to Evaluate the Safety of DEXYCUfor the Treatment of Inflammation Following Ocular Surgery for Childhood Cataract
- Trial name
- NCT05191706
- Testing
- Dexamethasone, Prednisolone Acetate Ophthalmic
- Where
- 9 sites in United States
- Volunteers
- 17 people
- Sponsor
- EyePoint Pharmaceuticals, Inc.
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.