Clinical trials: Lens Disease
Myopia
Contact Lens Optics and Visual Performance
This study will evaluate changes in visual performance at different pupil sizes between a single vision soft contact lens and multifocal soft contact lens, and compare refractive error measured between these two lenses with an…
- Trial name
- NCT05308069
- Testing
- Single vision contact lens, Multifocal contact lens
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- David A Berntsen, OD PhD
Age-Related Macular Degeneration
Five-year Incidence of Age-related Macular Degeneration in the Central Region of Portugal
To assess the five-year incidence of AMD in a population from the central region of Portugal, previously phenotypically characterized.
- Trial name
- AMDIncidencePT (NCT02748824)
- Where
- Portugal
- Volunteers
- 5,996 people, healthy volunteers welcome
- Sponsor
- Association for Innovation and Biomedical Research on Light and Image
Cataract, Lens Diseases
Correlations Between Lens Star and Phacoemulsification.
To assess correlations between lens star biometry parameters and phacoemulsification in clinical practice.
- Conditions
- Cataract, Lens Diseases, Lens Opacities
- Trial name
- NCT05290896
- Testing
- Phacoemulsification
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Benha University
Cataracts
Dispervise Ophthalmic Viscoelastic as an Agent to Ensure Watertight Wound Closure After Clear Corneal Cataract Incisions
The purpose of this study is to look at the ability of Viscoat to ensure proper wound closure.
- Trial name
- NCT01298973
- Testing
- Viscoat, Saline
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Innovative Medical
Cataract Senile
Precisight® Intraocular Lens Implantation for Cataract Treatment
The purpose of this study is to determine the refractive outcomes and optimize the clinical features of a new intraocular lens intended to treat the senile cataract.
- Trial name
- PEACE (NCT02970487)
- Testing
- Intraocular implant of the Precisight
- Where
- Philippines
- Volunteers
- 96 people
- Sponsor
- InfiniteVision Optics
Cataract, Age-Related
Comparison of Optical Quality With Different Placement of Refractive Multifocal Intraocular Lens
The study aims to compare postoperative optical quality between two different implanting position of a rotationally asymmetric MIOL [SBL-3 Lenstec; +3.00 diopters (D)], angle kappa based implantation and 0 to 180 degree…
- Trial name
- NCT03674840
- Testing
- angle kappa based SBL-3 implantation, 0 to 180 degree SBL-3 implantation
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Peking University Third Hospital
Diabetic Macular Edema
IVI Aflibercept Before and After Phaco in DME.
To study whether or not cataract surgery should be deferred until treating the co-existing diabetic macular edema (DME) using intravitreal (IVI) anti-vascular endothelial growth factor (anti-VEGF).
- Trial name
- NCT05731089
- Testing
- Phacoemulsification with IVI of aflibercept
- Where
- Kuwait
- Volunteers
- 40 people
- Sponsor
- Al Hadi Hospital
Presbyopia
Comparison of Three Soft Bifocal Contact Lenses
The primary purpose of the study is to compare the performance of three soft bifocal contact lenses in terms of the vision provided by the lenses.
- Trial name
- NCT00808340
- Testing
- balafilcon A, senofilcon A production, senofilcon A test
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Dry Eye
Ocular Effects of Scleral Lens Wear on Dry Eye Patients
The purpose of this study is to investigate the effects of scleral contact lens wear on a DE population using coated (Hydra-PEG) and uncoated (control) lenses.
- Trial name
- NCT05079321
- Testing
- Hydra-PEG, Uncoated
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Waterloo
Pain, Inflammation
Efficacy of Bromfenac Ophthalmic Solution in Patients Undergoing Cataract Surgery
This is an efficacy study of Bromfenac Ophthalmic Solution in cataract surgery.
- Conditions
- Pain, Inflammation, Cataract
- Trial name
- NCT01367249
- Testing
- Bromfenac Ophthalmic Solution
- Where
- United States
- Volunteers
- 440 people
- Sponsor
- Bausch & Lomb Incorporated
Myopia
Performance Evaluation of a New Daily Disposable Silicone Hydrogel Lens
The purpose of this study was to compare a new daily disposable, silicone hydrogel contact lens to marketed daily disposable, silicone hydrogel contact lenses.
- Trial name
- TUNGSTEN (NCT01371552)
- Testing
- delefilcon A contact lens, filcon II 3 contact lenses, narafilcon A contact lenses
- Where
- Canada
- Volunteers
- 119 people
- Sponsor
- CIBA VISION
Astigmatism
The Effect of the Changes in Cylinder Power and Axis of Toric Soft Contact Lenses on the Visual Quality, Satisfaction and Vision Acceptability in Astigmatic Subjects
Toric SCL combined spheric lens power with cylinder power and axis. However, in Indonesia, the availability of cylinder power and axis parameter variations between products are still narrow, with stock-keeping units (SKUs)…
- Trial name
- NCT06937489
- Testing
- Hydrogel conventional toric lenses with -10° axis misalignment, Hydrogel conventional toric lenses with +10° axis misalignment, Hydrogel conventional toric lenses with undercorrection of 0.5 D
- Where
- Indonesia
- Volunteers
- 20 people
- Sponsor
- Universitas Indonesia
Myopia
Clinical Assessment of a Daily Wear Monthly Replacement Soft Silicone Hydrogel Contact Lens
The purpose of this study is to assess the clinical performance of an investigational contact lens over 30 days of daily wear.
- Trial name
- NCT04476784
- Testing
- Lehfilcon A contact lenses, Comfilcon A contact lenses, CLEAR CARE
- Where
- 5 sites in United States
- Volunteers
- 66 people
- Sponsor
- Alcon Research
Cataracts, Visual Acuity Reduced Transiently
The Incidence of Glistenings in the 2017 Intraocular Lenses Made by Alcon and Abbott Medical Optics
The purpose of this study is to seek academic/non-industry research funding support to independently investigate the incidence and density of lens glistenings in cataract patients who are implanted with the latest generations of…
- Conditions
- Cataracts, Visual Acuity Reduced Transiently, Loss of Visual Contrast Sensitivity, Functional Visual Loss
- Trial name
- NCT03409185
- Testing
- Alcon 1 piece SA60AT lens, AMO 1-piece AABOO lens
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- University of Toronto
Glaucoma, Open-Angle, Cataract Complicated
Evaluation of Phacogoniotomy in Medically-controlled POAG
The goal of this multicenter non-inferiority randomized controlled trial is to compare the efficacy of phacoemulsification with intraocular lens implantation (PEI) combined with goniotomy (GT) and PEI combined with medical…
- Conditions
- Glaucoma, Open-Angle, Cataract Complicated, Goniotomy
- Trial name
- ECO (NCT06201455)
- Testing
- PEI+GT, PEI+MED
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Sun Yat-sen University
Cataract
Visual Performance of an Extended Depth of Focus IOL in an Emmetropic or Monovision Modality
Comparison of the visual performance of a refractive extended depth of focus intraocular lens in an emmetropic or monovision modality
- Trial name
- NCT06624826
- Testing
- Emmetropic modality, Monovision modality
- Where
- Austria
- Volunteers
- 60 people
- Sponsor
- Prim. Prof. Dr. Oliver Findl, MBA
Aphakia
Clinical Evaluation of the Lenstec Softec HP1 Intraocular Lens
The study is designed as a post market evaluation of the Softec HP1 IOL for continuance of the CE certificate. The primary effectiveness endpoint is to evaluate the safety and performance levels produced by this IOL in patients…
- Trial name
- NCT03900260
- Testing
- Softec HP1 Intraocular Lens
- Where
- 3 sites in United Kingdom
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Lenstec Incorporated
Astigmatism, Myopia
Effect of a Myopia Control Lens on the Astigmatism in Children
The goal of this clinical trial is to investigate over a one-year period the effect of myopia control spectacle lenses on astigmatism in children aged 6 to 13 years with myopia and astigmatism.
- Trial name
- MAC (NCT07810725)
- Testing
- Lenslet-based myopia control spectacle lens
- Volunteers
- 15 people
- Sponsor
- Essilor International
Cardiovascular Morbidity, Risk Reduction
Help Everyone Assess Risk Today: LEnten Nutrition Study (HEART-LENS)
The purpose of this study is to evaluate the impact of community health screening, health education and nutritional intervention on risk factors for cardiovascular disease in a predominantly African American population.
- Conditions
- Cardiovascular Morbidity, Risk Reduction, Nutrition Disorders
- Trial name
- NCT05057650
- Testing
- Vegan diet
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Anaesthesia, Cataract
A Comparison of One-site and Two-site Peribulbar Anaesthesia for Cataract Surgery at Kaduna, Nigeria
The aim of the study was to compare the efficacy and safety of single injection peribulbar anaesthesia against the classic double injection technique.
- Trial name
- NCT02150460
- Testing
- One-site peribulbar injection, Two- site peribulbar injection
- Where
- Nigeria
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Eye Centre, Kaduna
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