Clinical trials: Lens Disease
Corneal Astigmatism
Tomographic Analysis of Anterior, Posterior, Total Corneal Refractive Power Changes After Laser-assisted Keratotomy
To analyze the effect of femtolaser-assisted keratotomy on corneal astigmatism (anterior, posterior and Total corneal refractive power) measured by Scheimpflug tomography after laser lens surgery.
- Trial name
- NCT03097302
- Testing
- Laser keratotomy
- Volunteers
- 23 people
- Sponsor
- University Clinic Frankfurt
Cataract Extraction, Phacoemulsification
A Study Comparing Two Monofocal, Aspheric, Hydrophobic Acrylic Intraocular Lenses: the Alcon CLAREON® and the Abbott Medical Optics PCB00
This is a bilateral randomised controlled study to compare visual performance, refractive outcome, forward light scatter, patient satisfaction and objective measurement of glistenings following insertion of two monofocal…
- Conditions
- Cataract Extraction, Phacoemulsification, Glistenings, Intraocular Lens Implant
- Trial name
- NCT03364972
- Testing
- Cataract surgery
- Where
- United Kingdom
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Cataract
Clinical Outcomes With Bilateral Implantation of Odyssey IOLs
This study is a single center, ambispective study of visual outcomes after successful bilateral cataract surgery. Subjects will be assessed at least 3 months postoperatively at a single visit.
- Trial name
- NCT06550375
- Testing
- TECNIS Odyssey IOL
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Mann Eye Institute
Cataract, Surgery
Video-assisted Informed Consent for Cataract Surgery
The investigators will investigate whether video-assisted informed consent is superior to routine discussion for cataract patients about risks, benefits and alternatives to receiving phacoemulsification cataract extract and…
- Trial name
- NCT02185807
- Testing
- video-assisted group, control group
- Where
- 2 sites in China
- Volunteers
- 80 people
- Sponsor
- Guangzhou First People's Hospital
Myopia
Comparison of Hand Eye Coordination and Sports Vision Performance in Dual-Focus Multifocal Contact Lenses and Habitual Contact Lenses
The purpose of the study is to compare the hand-eye coordination and sports vision performance in participants while they are wearing their habitual contact lenses versus while wearing the dual-focus multifocal contact lenses.
- Trial name
- NCT07840209
- Testing
- Multifocal Contact Lens
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Ohio State University
Diabetes Mellitus
Comparison of Aqueous and Plasma Glucose Level in Diabetic Patients
Comparison of aqueous and plasma glucose level in diabetic patients High glucose concentrations in aqueous humor are thought to be related of diabetic ocular injury, including cataract and diabetic keratopathy.
- Trial name
- NCT02750098
- Testing
- Glucose measurement
- Volunteers
- 25 people
- Sponsor
- Sheba Medical Center
Myopia
Clinical Evaluation of Daily Disposable Contact Lenses
The objective of the study is to compare the overall subjective preference of filcon II 3 daily disposable silicone hyrogel contact lenses compared to etafilcon A and nelfilcon A daily disposable conventional hydrogel contact…
- Trial name
- NCT02097030
- Testing
- filcon II 3, etafilcon A, nelfilcon A
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- CooperVision, Inc.
Nearsightedness
Vault Evaluation After ICL Implantation
The purpose of this study is to evaluate the lens vault after implantation of an implantable collamer lens (ICL). The ICL is designed to be implanted in front of the eye, without removing the natural lens.
- Trial name
- NCT06229119
- Testing
- Implantable Collamer Lens
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Carolina Eyecare Physicians, LLC
Cataract, Anxiety
Delta-Wave Hypnoanalgesia for Reducing Perioperative Anxiety in Cataract Surgery
This prospective, randomized, single-blind trial evaluated the effect of delta-wave binaural beat audio hypnoanalgesia, a non-pharmacological hypnosis technique, on reducing perioperative anxiety and improving hemodynamic…
- Trial name
- NCT07099209
- Testing
- Delta-Wave Hypnoanalgesia
- Where
- Tunisia
- Volunteers
- 198 people
- Sponsor
- Military Hospital of Tunis
Presbyopia
Handling Comparison Between Two Contact Lens Types
Subjects will evaluate each study lens in a random order. The lenses will be worn in both eyes for a short period.
- Trial name
- NCT02310126
- Testing
- etafilcon A (multi-focal), etafilcon A (sphere)
- Where
- 8 sites in United States
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Refractive Error
Effectiveness of a Marketed One-Step Peroxide Lens Care Solution in Symptomatic Contact Lens Wearers
The purpose of this study is to assess improvement of palpebral roughness and associated symptoms with 3 months use of Clear Care®.
- Trial name
- NCT01996709
- Testing
- Hydrogen peroxide-based contact lens solution, Habitual contact lens solution, Habitual contact lenses
- Volunteers
- 142 people
- Sponsor
- Alcon Research
Refractive Error, Dry Eye
Determination of Cell Population in Solution-Induced Corneal Staining (SICS) and Symptomatic Versus Asymptomatic Lens Wearers
The purpose of the study is to investigate the corneal epithelial cell response associated with lens wear that results in solution-induced corneal staining (Phase1) and to determine the cell appearance in symptomatic and…
- Trial name
- ABBOTSFORD (NCT01629706)
- Testing
- Balafilcon A contact lens, Habitual contact lenses, Renu multi-purpose solution
- Volunteers
- 92 people
- Sponsor
- CIBA VISION
Dry Eye
Effects of 3% Diquafosol on Tear Film and Vision-related Quality of Life in Orthokeratology Lens Related Dry Eye
Investigate the effect of 3% Diquafosol on tear film and vision-related quality of life in dry eye patients wearing orthokeratology lenses(OK lens), and to provide reference for clinical treatment.This prospective, open label…
- Trial name
- NCT06537349
- Testing
- 3% Diquafosol tetrasodium
- Volunteers
- 30 people
- Sponsor
- He Eye Hospital
High Myopia, Cataract
Shanghai High Myopia Study
The purpose of this study is to evaluate the long-term visual outcome of the cataract surgery using a large-scale and comprehensive database of high myopic cataract and age-related cataract patients.
- Conditions
- High Myopia, Cataract, Visual Outcome, Genetic Anticipation
- Trial name
- NCT03062085
- Testing
- Cataract
- Where
- China
- Volunteers
- 60,000 people
- Sponsor
- Shanghai High Myopia Study Group
Vitreous Detachment, Cataract (Post-operative Cataract Surgery Follow-up)
Evaluation of Vitreous Modifications After Cataract Surgery
This study aims to evaluate changes in vitreous structure and the vitreoretinal interface following cataract surgery using spectral-domain optical coherence tomography (OCT).
- Trial name
- VitCat (NCT07816887)
- Testing
- cataract surgery
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University of Trieste
Cataract
Comparison of Two Fragmentation Modalities in Femtosecond Laser-assisted Cataract Surgery
Femtosecond laser-assisted cataract surgery consists in nuclear lens fragmentation, followed by ultrasound phacoemulsification of nuclear lens, which is then removed.
- Trial name
- SLICES (NCT02898909)
- Testing
- nuclear lens fragmentation in 8 pieces, nuclear lens fragmentation in 16 pieces
- Where
- France
- Volunteers
- 5 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Cataracts
Clinical Investigation of Corneal Incision Size After Intraocular Lens (IOL) Implantation
The purpose of this study is to compare corneal incision size after IOL implantation with the use of one of four IOL delivery systems (three preloaded IOL delivery systems and one manually loaded IOL delivery system).
- Trial name
- NCT02826421
- Testing
- UltraSert Preloaded Delivery System, iTec Preloaded Delivery System, iSert Preloaded Delivery System
- Volunteers
- 114 people
- Sponsor
- Alcon Research
Cataract
In Clinic Optometrist Insertion of Dextenza Prior to Cataract Surgery
To evaluate the clinical outcomes with optometrist pre-surgical insertion of DEXTENZA in the clinical office setting in patients undergoing same-day cataract surgery compared to standard of care steroid therapy.
- Trial name
- Prepare (NCT05023304)
- Testing
- Dextenza 0.4Mg Ophthalmic Insert, Topical prednisolone acetate
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Vance Thompson Vision
Diabetes Mellitus, Diabetes Complications
Diabetes Complications and Hearing Loss
Observation study, shows the relation between diabetes, its neurological and optical complication and hearing loss, by asking participants questions about there age,BMI,job,the history of any cataract,diabetes retinopathy or…
- Conditions
- Diabetes Mellitus, Diabetes Complications, Hearing Loss
- Trial name
- NCT06190938
- Where
- Syria
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Syrian Private University
Presbyopia
Performance of a Multifocal Contact Lens - Presbyopia Study
This is a four week study to evaluate the performance of a multifocal contact lens in habitual wearers of silicone hydrogel multifocal contact lenses.
- Trial name
- NCT02450747
- Testing
- etafilcon A MULTIFOCAL
- Where
- Canada
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
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