Clinical trials: Lens Disease
Myopia, Hyperopia
The Effect of Masking on Subjective Results During Daily Disposable Contact Lens Studies
The purpose of this study is to explore the effect of masking on subjective ratings for two daily disposable contact lenses.
- Trial name
- ARGON (NCT01155726)
- Testing
- Nelfilcon A contact lens, Nelfilcon A contact lens with comfort additive (DACP), unmasked, Nelfilcon A contact lens with comfort additive (DACP), masked
- Where
- Canada
- Volunteers
- 134 people
- Sponsor
- CIBA VISION
Cataract
Evaluation of Visual Acuity and Patient Satisfaction With AT LISA TRI 839MP Intraocular Lenses
The purpose of the study is to evaluate the far, intermediate and near visual acuities with a trifocal IOL.
- Trial name
- NCT01731743
- Testing
- AT LISA tri 839MP
- Where
- Germany
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Carl Zeiss Meditec AG
Cataract, Anxiety
Personalized Music for Anxiety During Cataract Surgery
This randomized controlled trial evaluated the effect of a personalized music intervention on anxiety and pain in patients undergoing cataract surgery under local anesthesia.
- Conditions
- Cataract, Anxiety, Pain
- Trial name
- NCT07767643
- Testing
- Structured Personalized Music Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Ege University
Aphakia, Corneal Astigmatism
Clinical Investigation of an AcrySof IQ PanOptix Toric Intraocular Lens
The purpose of this study is to evaluate the effectiveness and safety of the TFNT20 low cylinder power intraocular lens when implanted in the eye to replace the natural lens following cataract removal.
- Trial name
- NCT04542525
- Testing
- ACRYSOF IQ PanOptix Toric Trifocal IOL, Cataract surgery
- Where
- Japan
- Volunteers
- 32 people
- Sponsor
- Alcon Research
Myopia
1 Week Crossover Dispensing Study Between Two Soft Contact Lenses
The objective of this investigation is to compare the visual clinical performance of a silicone hydrogel daily disposable investigational contact lenses to a hydrogel daily disposable commercially available contact lenses.
- Trial name
- NCT06170658
- Testing
- Test Lenses (stenfilcon A), Control Lenses (omafilcon A)
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- CooperVision, Inc.
Refractive Error
Initial Performance of a Modified Daily Disposable Contact Lens
The purpose of this study is to evaluate the incidence of ocular discomfort device-related adverse events with DAILIES TOTAL1® with UV Absorber (DT1 UV) contact lenses compared with current DAILIES TOTAL1® (DT1) contact lenses.
- Trial name
- NCT02694835
- Testing
- Delefilcon A contact lenses with UV Absorber, Delefilcon A contact lenses
- Volunteers
- 81 people
- Sponsor
- Alcon Research
Glaucoma, Ocular Hypertension
Latanoprost Eluting Contact Lens for Treating Glaucoma and Ocular Hypertension
In this research study, we will assess the safety, tolerability, comfort, and feasibility of lowering intraocular pressure using a novel Contact Lens Drug Delivery System with latanoprost.
- Trial name
- NCT04500574
- Testing
- Latanoprost eluting contact lens, Topical Latanoprost
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Massachusetts Eye and Ear Infirmary
Cataract
Outcomes Following Phacoemulsification With 1.8 & 2.2mm Incision: Randomized Clinical Trial
Cataract surgical techniques have significantly changed in recent years with the widespread adoption of smaller and smaller clear corneal incisions for phacoemulsification.
- Trial name
- NCT01385878
- Testing
- Microcoaxial Phacoemulsification
- Where
- India
- Volunteers
- 110 people
- Sponsor
- Iladevi Cataract and IOL Research Center
Optical Biometer, Cataracts
Evaluation of Three SS-OCT and One PCI Optical Biometers in Eyes With Dense Cataract
To describe and compare the acquisition rate between different biometers in eyes with advanced cataracts
- Trial name
- BIO-CAT-DENSA (NCT05239715)
- Testing
- Ocular biometry
- Where
- Spain
- Volunteers
- 51 people
- Sponsor
- OFTALVIST (Oftalmología Vistahermosa S.L)
Keratoconus, Irregular Astigmatism
Wavefront Guided Scleral Lenses for Keratoconus and Irregular Astigmatism
Aberrations are the spreading of light from a point focus. Aberrations of the eyes can be objectively evaluated with a wavefront aberrometer.
- Conditions
- Keratoconus, Irregular Astigmatism, Corneal Ectasia, Aberration, Corneal Wavefront
- Trial name
- WFG Sclerals (NCT04698590)
- Testing
- Wavefront Guided Scleral Lenses, Traditional Scleral Lenses
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cornea and Laser Eye Institute
Myopia
Implantable Phakic Lens (IPCL) VS Implantable Collamer Lens
Phakic intraocular lenses (pIOL) of different designs and materials have been used effectively instead of corneal refractive surgery in certain situations.
- Trial name
- NCT04624035
- Testing
- Implantable Collamer Lens (ICL) in treatment of myopia in adults., Implantable Intraocular Lens (IPCL) in treatment of myopia in adults.
- Where
- 2 sites in Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Cataract Bilateral, Lens, Intraocular
Evaluation of Visual Function After Bilateral Implantation of EDOF IOLs
Since intermediate vision is becoming increasingly important in our day-to-day tasks, a new IOL was introduced (Acunex Vario) with this objective in mind.
- Conditions
- Cataract Bilateral, Lens, Intraocular, Lens Implantation, Intraocular, Pseudophakia
- Trial name
- Vario-NL (NCT05335408)
- Testing
- Acunex Vario intraocular lens, Alcon AcrySof IQ Vivity intraocular lens
- Where
- Netherlands
- Volunteers
- 32 people
- Sponsor
- Maastricht University Medical Center
Cataract
In Clinic Optometrist Insertion of Dextenza Prior to Cataract Surgery
To evaluate the clinical outcomes with optometrist pre-surgical insertion of DEXTENZA in the clinical office setting in patients undergoing same-day cataract surgery compared to standard of care steroid therapy.
- Trial name
- Prepare (NCT05023304)
- Testing
- Dextenza 0.4Mg Ophthalmic Insert, Topical prednisolone acetate
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Vance Thompson Vision
Dry Eye, Cataract
Lubricating Eye Drops After Routine Cataract Surgery
Patient satisfaction and dry symptoms in patients undergoing routine uncomplicated cataract surgery in NHS patients treated with prophylactic phosphate-free, preservative-free lubricant eye drops (0.3% cross linked sodium…
- Trial name
- NCT04465071
- Testing
- AEONTM Repair and AEONTM Protect Plus lubricating eye drops
- Where
- United Kingdom
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Presbyopia, Presbyopia Correction
Quality of Life in Presbyopes Using Single-vision Lens and Progressive Lens Correction
The goal of this clinical trial is to compare the quality of life (QOL) of presbyopes wearing progressive addition lenses (PALs) with that of those wearing single-vision spectacles (SVSs) for near correction.
- Trial name
- NCT06699784
- Testing
- Progressive lenses intervention, Single-vision lenses intervention
- Volunteers
- 74 people
- Sponsor
- The Hong Kong Polytechnic University
Cataract
Brillouin Scanning in Cataractous Eyes
To provide first results for biomechanical properties of cataractous lenses via Brillouin microscopy and correlations between LOCS III grading, cataractous lens scans from optical coherence tomography (OCT), and intraoperative…
- Trial name
- NCT07425626
- Testing
- Brillouin-Microscopy
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- Prim. Prof. Dr. Oliver Findl, MBA
Glaucoma, Cataract
Combined Phacotube vs Phacotrabeculectomy:A Randomized Controlled Trial
The aim of this study is to compare the effectiveness and safety of combined phacoemulsification, posterior chamber intraocular lens implantation , trabeculectomy (phacotrabeculectomy) with phacoemulsification, intraocular lens…
- Trial name
- NCT00273221
- Testing
- Glaucoma Implant Surgery, trabeculectomy, phacoemulsification
- Where
- Singapore
- Volunteers
- 50 people
- Sponsor
- National University Hospital, Singapore
Cataracts, Cataract Surgery
Endothelial Cell Loss and Induced Astigmatism After Wound-directed and Wound-assisted IOL Injection
The purpose of this study is to determine if there is any difference in astigmatism (eye surface curvature) or corneal endothelial cell density (the inner cell lining of the eye surface) after two different methods for inserting…
- Trial name
- NCT01250964
- Testing
- Lens insertion during cataract surgery
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of North Carolina, Chapel Hill
Myopia, Astigmatism
Comparative In-Vivo Wetting Characteristics of Silicone Hydrogel Materials With Selected Lens Care Systems
The purpose of this study is to evaluate the lipid uptake, wetting characteristics, and visual performance of AIR OPTIX® AQUA and ACUVUE® OASYS® with HYDRACLEAR® contact lenses when used in conjunction with two contact lens care…
- Conditions
- Myopia, Astigmatism, Refractive Error
- Trial name
- NCT01699750
- Testing
- Lotrafilcon B contact lenses, Senofilcon A contact lenses, OPTI-FREE® PUREMOIST® MPDS
- Where
- United States
- Volunteers
- 109 people
- Sponsor
- Alcon Research
Presbyopia, Refractive Error
Dispensing Study to Assess Visual Performance of Prototype Contact Lenses
The aim of this study is to assess visual performance of prototype soft contact lens designs compared to commercially available contact lenses over one-week of lens wear.
- Trial name
- NCT02214797
- Testing
- Etafilcon A, Lotrafilcon B , Senofilcon A
- Where
- Australia
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Brien Holden Vision
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