Clinical trials: Lens Disease
Myopia
Comparison of Clinical Performance and Subjective Preference of Three Contact Lenses
The purpose of this study is to evaluate the clinical performance and subject's preference out of three LRE (Limbal Ring Enhancing) lens types: etafilcon A (Johnson\&Johnson), methafilcon A (Interozzo), and methafilcon A…
- Trial name
- NCT03134599
- Testing
- etafilcon A, methafilcon A - Interozzo, methafilcon A - CVI (CooperVision)
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- CooperVision, Inc.
Ectopia Lentis, Dislocation, Lens
Follow up Study on Visual Prognosis and Complications of Ectopia Lentis Lens
This is a single-centre, observational cohort study with the following objectives: Firstly, the investigators aim to evaluate the vision-related quality of life and mental health status in congenital ectopia lentis patients.
- Trial name
- NCT05654025
- Where
- China
- Volunteers
- 604 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Cataract
Evaluation of the Rotational Stability of the Monofocal SISA Implant Following Cataract Surgery
A good efficacy as well as good rotary stability is expected with the ocular implant.
- Trial name
- SISALens (NCT03356847)
- Testing
- Fitting of ocular implant
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Presbyopia, IOL, Cataract
Evaluation of the Visual Acuity Curves of an Enhanced Monofocal Intraocular Lens
The primary objective of this study is to evaluate postoperative visual acuity curves in pseudophakic patients following unilateral or bilateral implantation of the enhanced monofocal TECNIS Eyhance IOL, using the DDARTVC.
- Trial name
- IOL-VAC (NCT07439835)
- Testing
- Phacoemulsification with enhanced monofocal IOLs
- Where
- Greece
- Volunteers
- 62 people
- Sponsor
- Democritus University of Thrace
Cataract
Evaluation of the Rotational Stability of The AcrySof Toric Intraocular Lens in the Capsular Bag in High Myopic Subjects
The purpose of this study is to evaluate the stability and efficacy of The AcrySof Toric intraocular lens in the bag in high myopic subjects.
- Trial name
- NCT01351233
- Testing
- Cataract Surgery
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Wenzhou Medical University
Cataract Bilateral, Astigmatism Bilateral
Symfony Toric Intraocular Lens Visual Outcomes
In July 2016, the FDA approved an extended depth of focus (EDOF) IOL (Tecnis Symfony, Abbott Medical Optics) helping to improve the sharpness of vision at near, intermediate and far distances reducing the need of glasses after…
- Trial name
- NCT03082599
- Testing
- Presbyopia and astigmatism correcting intraocular lens
- Where
- 4 sites in United States
- Volunteers
- 120 people
- Sponsor
- Carolina Eyecare Physicians, LLC
Cataract Surgery, Cataract
Evaluation of Head-Mounted Spatial Computing and Three-Dimensional (3D) Visualization in Ocular Microsurgery: A Safety and Workflow Study
The purpose of this research is to evaluate the use of the research study device, the Apple Vision Pro head-mounted spatial computing display, with the Zeiss Artevo 850 digital microscope system, for the visualization during…
- Trial name
- NCT07301385
- Testing
- Apple Vision Pro (Head-Mounted Spatial Computing Display), Zeiss Artevo Digital Surgical Microscope
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Sharp HealthCare
Ametropia
Evaluation of the Performance of Non-molded Soft Contact Lenses
To evaluate the performance of the study soft lens for vision, comfort, physiology and lens surface properties.
- Trial name
- NCT00371787
- Testing
- Soft contact lens
- Where
- Canada
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Waterloo
Cataract
Clinical Outcome at 5 Years After Implantation of the Liberty677MY Multifocal Intraocular Lens
The study will assess visual outcomes, light disturbances and patients' satisfaction after implantation with the Liberty677MY multifocal IOL, as well as protection of PCO development within 5 year follow-up.
- Trial name
- NCT04220255
- Testing
- Liberty677MY Multifocal IOL
- Where
- Hungary
- Volunteers
- 50 people
- Sponsor
- Medicontur Medical Engineering Ltd
Cataract, Surgery
Femtosecond Laser Assisted Cataract Surgery in The NHS
This study aims to examine the health economic impact of adopting femtosecond laser technology to assist high volume cataract surgery (FLACS) within a state-funded healthcare system, the National Health Service (NHS).
- Trial name
- NCT02825693
- Testing
- Conventional cataract surgery (phacoemulsification), Femtosecond laser assisted cataract surgery
- Volunteers
- 400 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Dry Eye Syndrome
Efficacy Comparative Study Between Tears Again®, Opticol® and Optive®
Primary Purpose: To compare the efficacy in treating dry eye syndrome in contact lens wearers or computer users of Tears Again® versus Opticol® versus Optive® Secondary Purpose: Subjective evaluation of symptomatology Evaluation…
- Trial name
- NCT00893243
- Where
- Portugal
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Hospital de Sao Sebastiao
Refractive Error, Myopia
Comparative Evaluation of Contact Lens Centering of DAILIES® AquaComfort Plus® Versus 1-DAY ACUVUE® MOIST® in Japan
The purpose of this study is to evaluate lens centration and subjective impressions of DAILIES® AquaComfort Plus® (DACP) lenses compared to 1-DAY ACUVUE® MOIST® (1DAM) lenses in ball sports players.
- Conditions
- Refractive Error, Myopia, Myopic Astigmatism
- Trial name
- NCT02103309
- Testing
- Nelfilcon A contact lenses, Etafilcon A contact lenses
- Volunteers
- 42 people
- Sponsor
- Alcon Research
Presbyopia
A Study to Evaluate a Mid Add Multi-Focal Soft Contact Lens
This study is to evaluate the product performance of the investigational LD127025 MF mid add soft contact lens compared to CIBA Vision's Air Optix Aqua MF MED add soft contact lenses when used among currently adapted soft contact…
- Trial name
- NCT01959178
- Testing
- LD127025 MF, Air Optix Aqua MF
- Where
- United States
- Volunteers
- 146 people
- Sponsor
- Bausch & Lomb Incorporated
Myopia
Contact Lenses and Myopia
The objective of this study is to determine if multifocal contact lenses affect accommodation and/or binocular vision when worn by pediatric patients.
- Trial name
- CLAM (NCT02180347)
- Testing
- Contact lenses
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- State University of New York College of Optometry
Dry Eye
Ocular Effects of Scleral Lens Wear on Dry Eye Patients
The purpose of this study is to investigate the effects of scleral contact lens wear on a DE population using coated (Hydra-PEG) and uncoated (control) lenses.
- Trial name
- NCT05079321
- Testing
- Hydra-PEG, Uncoated
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Waterloo
Dry Eye
Effects of 3% Diquafosol on Tear Film and Vision-related Quality of Life in Orthokeratology Lens Related Dry Eye
Investigate the effect of 3% Diquafosol on tear film and vision-related quality of life in dry eye patients wearing orthokeratology lenses(OK lens), and to provide reference for clinical treatment.This prospective, open label…
- Trial name
- NCT06537349
- Testing
- 3% Diquafosol tetrasodium
- Volunteers
- 30 people
- Sponsor
- He Eye Hospital
Cataract
Post-refractive IOL Outcomes With Clareon TruPlus
This is a prospective, single-arm, single-center, single-surgeon study evaluating the Clareon TruPlus IOL in post-refractive cataract patients. Subjects will be assessed up to 3 months post-operatively.
- Trial name
- NCT07610226
- Testing
- Clareon TruPlus
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Laser Defined Vision
Anxiety
Investigating Predictors of Outcomes From LENS
Anxiety is a very common mental health problem. For people living with anxiety, it can have a huge impact on their lives. There are treatments that can help, such as Cognitive Behavioural Therapy (CBT).
- Trial name
- NCT07339917
- Testing
- Learning Effective New Strategies (LENS)
- Volunteers
- 4,400 people
- Sponsor
- King's College London
Refractive Errors, Myopia
Clinical Comparison of 2 Daily Disposable Contact Lenses - Pilot Study 2
The primary objective of this study is to evaluate the overall performance of PRECISION1 contact lenses when compared to Clariti 1-Day contact lenses.
- Trial name
- NCT04528017
- Testing
- Verofilcon A contact lenses, Somofilcon A contact lenses
- Where
- 4 sites in United States
- Volunteers
- 56 people
- Sponsor
- Alcon Research
Cataract
Phacoemulsification Sleeves
Incision size in cataract surgery is related to induced surgical astigmatism, chamber stability, and surgical efficiency. Sleeves of different diameters change the size of the surgical incision and amount of fluid allowed into…
- Trial name
- NCT00289068
- Testing
- Phacoemulsification Sleeve surgery, Phacoemulsification Sleeves surgery, Phacoemulsification Sleeves
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Oklahoma
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