Clinical trials: Lens Disease
Normal Non-fluency, Cataract
Comparative Study of the Optical Biometer for Measurements of the Eye
The primary purpose of this comparative clinical study is to collect clinical data to demonstrate the equivalence of the investigational device to the predicate device for measurements of the eye.
- Conditions
- Normal Non-fluency, Cataract, Aphakic Eye, Eyes With Corneal Abnormality
- Trial name
- NCT01729962
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Nidek Co. LTD.
Refractive Error, Myopia
Clinical Performance of a New Daily Disposable Contact Lens Worn in an Established Contact Lens Wearing Population
This study seeks to evaluate the clinical and subjective performance of a new daily disposable soft contact lens.
- Trial name
- NCT00708643
- Testing
- Habitual Silicone Hydrogel Contact Lens, narafilcon A
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Cataract
Dexmedetomidine Versus Midazolam for Peribulbar Block
50 patients of both sexes, ages 18 to 75, who were scheduled for cataract surgery and had physical status I or II according to the American Society of Anesthesiologists were included in this study.
- Trial name
- peribulbar (NCT06784843)
- Testing
- Dexmedetomidine as an adjuvant to local anesthesia for peribulbar block, Midazolam as an adjuvant to local anesthesia for peribulbar block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Suez Canal University
Cataract
Comparison of Epinephrine and Phenylephrine/Ketorolac With Regards to Pupil Size
The objective of this study is to compare the maintenance of intraoperative mydriasis during cataract surgery between two drugs: epinephrine, which has routinely been used for decades, and Omidria, a newly FDA approved…
- Trial name
- NCT02895035
- Testing
- Phenylephrine-ketorolac, Epinephrine
- Volunteers
- 59 people
- Sponsor
- Milton S. Hershey Medical Center
Cataract, Juvenile
Optic Capture Without Anterior Vitrectomy in Pediatric Cataract Surgery
Purpose: To compare two pediatric cataract surgery procedures: intraocular lens (IOL) optic capture without anterior vitrectomy (AV) and in-the-bag IOL implantation with AV.
- Trial name
- NCT05461040
- Testing
- optic capture, In-the-bag implantation of Intraocular lens
- Where
- Turkey (Türkiye)
- Volunteers
- 37 people
- Sponsor
- Ege University
Cataract
PREVAIL VII: Cataract Surgery in Ebola Survivors
Objective: Zaire ebolavirus is a single-stranded RNA virus associated with high morbidity and mortality. The most recent epidemic of Ebola virus disease (EVD) in West Africa resulted in over 11,000 deaths and disabling sequelae…
- Trial name
- NCT03309020
- Testing
- Cataract surgery
- Where
- Liberia
- Volunteers
- 37 people
- Sponsor
- National Eye Institute (NEI)
Myopia, Hyperopia
Clinical Investigation of the Vision-R800 Device.
Randomized, bilateral, cross-over dispensing study of a standard and VR800 refraction and associated spectacle lenses.
- Conditions
- Myopia, Hyperopia, Astigmatism, Presbyopia
- Trial name
- NCT04208750
- Testing
- Vision R-800 Phoropter, Standard Phoropter
- Where
- United States
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Pete Kollbaum, OD, PhD
Dry Eye
Single-Arm Study of a Treatment for Dry Eye in People Who Struggle to Wear Contact Lenses
This research study is to see if using Lacrifill is safe, easy to use, and helpful for people who wear contact lenses but can't wear them comfortably for long.
- Trial name
- NCT07510620
- Testing
- Lacrifill
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Vision Innovation Centers of Pennsylvania, LLC d/b/a Eye Care Specialists
Measurement of the Elasticity of the Anterior Eye Segment
A Pilot Study to Test the Safety and Feasibility of a Brillouin Ocular Analyzer
A Brillouin ocular analyzer uses a low-power near infrared laser light to probe the viscoelastic properties of the cornea and crystalline lens in the eye.
- Trial name
- Brillouin I (NCT01775007)
- Testing
- Brillouin Ocular Analyser
- Where
- 2 sites in United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Cataract
Clinical Investigation of the Modified Rayner Monofocal Aspheric 600C (With Axis Marks) Intraocular Lens
This will be a prospective, open-label, 125 subject (maximum), two-year multicentre investigation to assess the safety, effectiveness and rotational stability of the modified 600C (axis marks) intraocular lens (IOL) in subjects…
- Trial name
- NCT02378636
- Testing
- 600S
- Where
- United Kingdom
- Sponsor
- Rayner Intraocular Lenses Limited
Cataracts
Modified Intraocular Lens to Reduce Eye Inflammation After Cataract Surgery in Uveitis Patients
This study will test the effectiveness of an intraocular lens treated with heparin in reducing or preventing inflammation after cataract surgery in patients with uveitis.
- Trial name
- NCT00001311
- Testing
- heparin-surface modified intraocular lens
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- National Eye Institute (NEI)
Contact Lenses, Presbyopia
Clinical Performance of Verofilcon A Toric Contact Lenses
The goal of this clinical trial is to [primary purpose: is to determine if Total30 Multi focal toric conntact lensesare comfortable and the willigness for those who have previously worn reusable toric contact lenses are willing…
- Trial name
- NCT07586982
- Testing
- Total 30 multi foric contact lenses
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Southern College of Optometry
Cataract, Glaucoma
Evaluation of the Bimatoprost Implant System Used in Combination With the SpyGlass Intraocular Lens Compared to Timolol Ophthalmic Solution
This trial is a randomized study to evaluate and compare two doses of the Bimatoprost Implant System used in combination with the SpyGlass IOL to Timolol Ophthalmic Solution in participants with mild to moderate open-angle…
- Conditions
- Cataract, Glaucoma, Ocular Hypertension
- Trial name
- Tigris (NCT06120842)
- Testing
- Bimatoprost Implant System (High Dose), Bimatoprost Implant System (Low Dose), Timolol Maleate Ophthalmic Solution, 0.5%
- Where
- United States
- Volunteers
- 201 people
- Sponsor
- SpyGlass Pharma, Inc.
Ametropia
The Clinical Comparison of Somofilcon A 1 Day and Nelfilcon A Daily Disposable Contact Lenses
This subject-masked, randomized, bilateral crossover study will compare the clinical performance and subjective acceptance of the somofilcon A 1 day soft contact lens with the nelfilcon A daily disposable lens when used on a…
- Trial name
- NCT04067141
- Testing
- somofilcon A, nelfilcon A
- Where
- United Kingdom
- Volunteers
- 70 people
- Sponsor
- CooperVision, Inc.
Myopia, Hyperopia
Comparison of Contact Lens Maintenance Systems for Silicone Hydrogel Lenses
The primary purpose of this study is to investigate the performance of contact lens maintenance systems when used with silicone hydrogel contact lenses during daily wear over a period of 1 month.
- Trial name
- NCT00363623
- Testing
- Silicone hydrogel contact lens
- Where
- Australia
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Melbourne
Ptosis, Blepharoptosis
Bandage Contact Lens in Post Operative Ptosis Patients
This study is being conducted to determine whether the use of bandage contact lens after ptosis surgery provides any benefits for the patient or is unnecessary.
- Trial name
- NCT03375879
- Testing
- Bandage contact lens
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- St. Joseph's Healthcare Hamilton
Refractive Error
Tear Film Evaluation of Dailies® AquaComfort Plus® Multifocal and Toric
The purpose of this study is to evaluate the pre lens tear film characteristics of DAILIES® Aqua Comfort Plus® Multifocal (DACP MF) and Toric (DACP Toric) compared to DAILIES® Aqua Comfort Plus® Sphere (DACP) daily disposable…
- Trial name
- NCT02289742
- Testing
- Nelfilcon A multifocal contact lenses, Nelfilcon A toric contact lenses, Nelfilcon A sphere contact lenses
- Volunteers
- 48 people
- Sponsor
- Alcon Research
Cataracts
Evaluation of Real-World Data on the Performance of the TECNIS Odyssey™ IOL
Retrospective collection of data from medical records, multicenter, post-market clinical follow-up study.
- Trial name
- NCT05991960
- Testing
- Intervention
- Where
- 12 sites in United States
- Volunteers
- 96 people
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
Ametropia
Study of Soft Contact Lens Use With 7 Day Extended Wear
To compare the safety and efficacy of the CVI silicone-hydrogel lens worn on an extended wear basis for a period of up to 7 days and 6 nights with the Acuvue 2 soft contact lenses.
- Trial name
- NCT00597467
- Testing
- VISA (comfilcon A) Silicone Hydrogel Soft contact lens, Acuvue 2 Soft Contact Lens
- Where
- 23 sites in United States
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Cataracts
Clinical Investigation of Corneal Incision Size After Intraocular Lens (IOL) Implantation
The purpose of this study is to compare corneal incision size after IOL implantation with the use of one of four IOL delivery systems (three preloaded IOL delivery systems and one manually loaded IOL delivery system).
- Trial name
- NCT02826421
- Testing
- UltraSert Preloaded Delivery System, iTec Preloaded Delivery System, iSert Preloaded Delivery System
- Volunteers
- 114 people
- Sponsor
- Alcon Research
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