Clinical trials: Lens Disease
Cataract
Ketorolac vs. Steroid in the Prevention of CME
Evaluate if the incidence of sub clinical CME can be significantly reduced by use of peri-operative Acular LS plus Pred Forte when compared with Pred Forte alone in normal cataract patients.
- Trial name
- NCT00348244
- Testing
- Ketorolac, Prednisolone Acetate
- Where
- United States
- Sponsor
- Innovative Medical
Cataract, Pseudophakia
Correlation Between Sulcus Anatomy and Other Parameters After Horizontal & Vertical Intraocular Lens (IOLs) Placements
Usually following cataract surgery patients would expect to have normal distance vision and not require the use of distance glasses. However, in clinical practice desired vision post cataract surgery is not achieved sometimes.
- Trial name
- NCT04208633
- Testing
- Horizontal placement of the intraocular lens in the capsular bag, Vertical placement of the intraocular lens in the capsular bag
- Where
- United Kingdom
- Volunteers
- 46 people
- Sponsor
- Brighton and Sussex University Hospitals NHS Trust
Multiple Myeloma
Revlimid® Capsules Special Drug Use-results Survey (in Patients With Newly-diagnosed Multiple Myeloma [NDMM])
To understand the safety and efficacy of Revlimid® 2.5mg and 5 mg Capsules (hereinafter referred to as Revlimid) in all patients who are treated with it under the actual condition of use pursuant to the conditions of approval. 1.
- Trial name
- NCT02741544
- Where
- Japan
- Volunteers
- 578 people
- Sponsor
- Celgene
Cataract
Bilateral Monofocal Versus Monofocal-EDOF IOL Implantation: Quality of Vision Comparison
The goal of this clinical trial is to compare visual quality after cataract surgery between two groups: bilateral monofocal intraocular lenses (IOL) and monofocal and contralateral extended depth-of-focus (EDOF) IOL implantation.
- Trial name
- COMEDI (NCT06002399)
- Testing
- cataract surgery
- Where
- Belgium
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Cataract
Visual Function After Implantation of Bilateral AcrySof ReSTOR Aspheric +3
A prospective evaluation of the visual parameters in a series of patients bilaterally implanted with AcrySof ReSTOR +3 Intraocular Lens (IOL).
- Trial name
- NCT00719732
- Testing
- ReSTOR
- Where
- United States
- Volunteers
- 218 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Cataract
Evaluating Refractive and Visual Outcomes With the Alcon Toric ReSTOR +2.5 and +3.0 Models
The study will evaluate visual acuity and visual function with a 'blended' ReSTOR Toric intraocular lens (IOL) implantation after cataract surgery.
- Trial name
- NCT03856944
- Testing
- ReSTOR Toric
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Gainesville Eye Associates
Cataract, Presbyopia Correction
Evaluation Of Patient Satisfaction And Quality Of Vision After EDOF Or Trifocal IOL Implantation
Brief Summary of the Study The goal of this clinical study is to compare the quality of vision and patient satisfaction after cataract surgery using two different approaches to multifocal intraocular lenses (IOLs).
- Trial name
- TRIEDOF IOLS (NCT07295119)
- Testing
- Fusion EDOF IOL Implantation, Bilateral Trifocal IOL Implantation
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Ocular Inflammation, Cataract
Efficacy and Safety of Saturno IIB Association on the Control of Ocular Inflammation Post-phacoemulsification
The purpose of this study is to evaluate the efficacy of Saturno II association on the control of ocular inflammation post-phacoemulsification
- Trial name
- NCT03580473
- Testing
- SATURNO II association, Vigadexa®
- Where
- Brazil
- Volunteers
- 118 people
- Sponsor
- EMS
Myopia
Wearing Behavior and Eye Length Changes in Children With Myopia Wearing Myopia Control Spectacle Lenses
The goal of this clinical trial is to learn how children with myopia aged 8 to 15 years move their eyes and heads during near-vision tasks while wearing different spectacle lenses, and if wearing myopia control spectacle lenses…
- Trial name
- NCT07780851
- Testing
- Single Vision Lens (SVL), Myopia Control Lens (MCL)
- Where
- Singapore
- Volunteers
- 20 people
- Sponsor
- Essilor International
Myopia
Visual Outcomes And Contrast Sensitivity After Myopic Wavefront-Optimized Lasik With Nexisvision Shield Or Bandage Contact Lens
Evaluate visual outcomes and contrast sensitivity for subjects undergoing bilateral myopic LASIK with a Nexisvision Shield or bandage contact lens placed postoperatively.
- Trial name
- NCT01706237
- Testing
- Nexisvision shield
- Volunteers
- healthy volunteers welcome
- Sponsor
- Durrie Vision
Inflammation, Pain
Loteprednol Ophthalmic Gel for the Treatment of Ocular Inflammation and Pain Following Cataract Surgery
The objective of this study is to evaluate the safety and efficacy of loteprednol etabonate ophthalmic gel
- Conditions
- Inflammation, Pain, Cataract
- Trial name
- NCT01996839
- Testing
- Loteprednol Etabonate Gel (BID), Loteprednol Etabonate Gel (TID), Vehicle (BID)
- Where
- United States
- Volunteers
- 514 people
- Sponsor
- Bausch & Lomb Incorporated
Cataract, Lens Opacities
Clinical Investigation of the Multifocal IOL POD F GF in Cataracteous Eyes
To evaluate effectiveness and safety of the POD F GF Intraocular Lens (IOL) when implanted to replace the natural lens following cataract removal
- Conditions
- Cataract, Lens Opacities, Presbyopia
- Trial name
- NCT04699266
- Testing
- Assigned Intervention (POD F GF)
- Where
- Japan
- Volunteers
- 23 people
- Sponsor
- Beaver-Visitec International, Inc.
Binocular Vision Disorder
Binocular Vision Alternations and fMRI Activation After ICL Implantation for High Myopia
Implantable collamer lens (ICL) is one of the most effective operation for high myopia. Due to refractive correction changed, and prism effect of the spectacle removed, in the early stage after ICL implantation, binocular…
- Trial name
- NCT05633212
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Refractive Ametropia
Clinical Evaluation of a Manufacturing Process for a Frequent Replacement Silicone Hydrogel Multifocal Contact Lens
The purpose of this clinical trial was to evaluate the clinical performance of a manufacturing process on a frequent replacement multifocal contact lens.
- Trial name
- NCT05765227
- Testing
- Lehfilcon A multifocal contact lenses, Lotrafilcon B multifocal contact lenses, Hydrogen peroxide-based cleaning and disinfection system
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Alcon Research
Cataract
Clinical Outcome After Implantation of Two Different Multifocal Toric IOLs: Liberty (677MTY) and PanOptix®
This study is to compare the rotational stability, visual outcome and patient satisfaction after implantation with either Liberty 677MTY, a multifocal diffractive-refractive IOL based on EPS technology manufactured by Medicontur…
- Trial name
- NCT05895396
- Where
- Hungary
- Volunteers
- 35 people
- Sponsor
- Medicontur Medical Engineering Ltd
Aphakia
Artisan Aphakia Lens for the Correction of Aphakia in Children
The purpose of this study is to determine the safety and effectiveness of the Artisan Aphakia Lens in the treatment of aphakia in children.
- Trial name
- NCT01547442
- Testing
- Artisan Aphakia Intraocular Lens
- Where
- 19 sites in United States, Canada
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Ophtec USA
Irregular; Contour of Cornea, Keratoconus
Scleral Versus Corneal RGP Contact Lenses in Irregular Cornea Disorders
The most common causes for irregular cornea (IC) in hospital contact lens practice are Keratoconus (KC) and related cornea thinning disorders.
- Conditions
- Irregular; Contour of Cornea, Keratoconus, Pellucid Marginal Corneal Degeneration, Injury of Cornea
- Trial name
- NCT02444923
- Testing
- Scleral rigid gas permeable contact lenses (SRGPcl) (Zenlens™), Corneal Rigid gas Permeable contact lenses (CRGPcl) (Rose K2)
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- London South Bank University
Ocular Surface Disease
LK Scleral Lens for Patients With Intractable Ocular Surface Diseases
Scleral lenses have emerged as an efficacious treatment option for various types of intractable ocular surface diseases with many advantageous results.
- Trial name
- NCT04535388
- Testing
- LK scleral lens
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Cataract Unilateral, Aphakia
Prospective Clinical Trial to Evaluate the Safety and Effectiveness of the IOL
To establish the safety and effectiveness of the CT LUCIA 611P posterior chamber intraocular lens for the correction of aphakia following extracapsular cataract extraction via phacoemulsification in adult patients.
- Trial name
- NCT03451786
- Testing
- IOL
- Where
- United States
- Volunteers
- 369 people
- Sponsor
- Estelle Poineau
Cataract, Intraocular Lens
Agreement of Ocular Biometry and Intraocular Lens Power Between OA-2000 and Pentacam AXL in Cataract Patients
This study aim to evaluate the agreement of ocular biometric parameters and intraocular lens between two devices (OA-2000 and Pentacam AXL) in patients with cataract.
- Trial name
- NCT07500272
- Testing
- Swept-source optical coherence tomography with Placido-disc topography, Scheimpflug tomography with partial coherence interferometry
- Where
- Thailand
- Volunteers
- 94 people
- Sponsor
- Burapha University
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