Clinical trials: Lens Disease
Myopia
Long Term Safety Protocol for the AcrySof CACHET Phakic Lens
The purpose of this long term safety study is to estimate the annualized endothelial cell loss (ECL) rate (for up to 10 years following date of implantation) of subjects previously implanted with the ACRYSOF CACHET Phakic…
- Trial name
- NCT01497067
- Testing
- ACRYSOF CACHET Phakic Lens (L-series)
- Where
- United States
- Volunteers
- 657 people
- Sponsor
- Alcon Research
Myopia
S.T.O.P.® Technology Contact Lenses Versus Dual-focus Contact Lenses for Slowing Down Myopia Progression in Children
To compare the rate of myopia progression of contact lenses utilising S.T.O.P.® technology against MiSight® contact lenses.
- Trial name
- NCT05243836
- Testing
- S.T.O.P® F2, S.T.O.P® DT, MiSight®
- Where
- 7 sites in China, India and 1 more
- Volunteers
- 441 people
- Sponsor
- nthalmic Pty Ltd
Cataract, Exfoliative Glaucoma
Measurement of Ocular Tensional Fluctuation by Triggerfish Lens Before and After Cataract Surgery in Patients With Exfoliative Glaucoma
Glaucoma is a very frequent disease in Brittany. In glaucoma the retinal ganglion cells and their axons slowly die with visible changes at the optic nerve head (cupping).
- Trial name
- TRIGGERFISH (NCT02658071)
- Where
- France
- Volunteers
- 6 people
- Sponsor
- University Hospital, Brest
Dislocated Intraocular Lens
Modification of Scleral Suture Fixation of Dislocated IOL
A prospective randomized study on patients with late in the bag intraocular lens (IOL) dislocation after cataract surgery. Two surgical techniques of suturing of IOL to the sclera will be compared in the study.
- Trial name
- NCT04150263
- Testing
- Intraocular lens (IOL) ab externo scleral suture fixation, Modified IOL ab externo scleral suture fixation
- Where
- Sweden
- Volunteers
- 117 people
- Sponsor
- St. Erik Eye Hospital
Cataract
Monovision vs Multifocal Lens Insertion in Cataract Patients
The investigators would like to assess whether monovision correction of multifocal lens insertion provides more satisfaction to cataract patients following an uncomplicated phacoemulsification surgery.
- Trial name
- NCT01998698
- Testing
- Phacoemulsification surgery
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- Democritus University of Thrace
Aphakia
Artisan Aphakia Lens for the Correction of Aphakia (Secondary) in Adults
This study will determine the safety and effectiveness of the Artisan Aphakia Lens when used as a secondary implant to correct aphakia in adults.
- Trial name
- NCT01547429
- Testing
- Artisan Aphakia Intraocular Lens
- Where
- 18 sites in United States, Canada
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Ophtec USA
Cataract, Phacoemulsification
Comparison of Manual Super Small Incision Cataract Surgery and Phacoemulsification
The purpose of this study is to compare the safety and efficacy of manual super small incision cataract surgery (MSSICS) and Phacoemulsification.
- Trial name
- NCT01146964
- Testing
- MSSICS, Phacoemulsification
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Wenzhou Medical University
Cataracts
AcrySof® IQ ReSTOR® +2.5 D Multifocal Intraocular Lens (IOL) Model SN6AD2 [SV25T0] in Japan
The purpose of this study is to evaluate safety and effectiveness of AcrySof® IQ ReSTOR® +2.5 D Multifocal IOL Model SN6AD2 [SV25T0] in Japanese cataract patients.
- Trial name
- NCT01605877
- Testing
- AcrySof® IQ ReSTOR® +2.5 D Multifocal IOL Model SN6AD2 [SV25T0]
- Where
- 2 sites in Japan
- Volunteers
- 70 people
- Sponsor
- Alcon Research
Cataract
Clinical Evaluation of FLACS With Combination of LenSx® and Centurion®
The purpose of this study is to evaluate cumulative dissipated energy (CDE), endothelial cell loss, and average torsional amplitude with combination of LenSx® and Centurion® compared to conventional cataract surgery.
- Trial name
- NCT03479944
- Testing
- FLACS, Manual conventional surgery, CENTURION® Vision System
- Where
- Japan
- Volunteers
- 57 people
- Sponsor
- Alcon Research
Dry Eye Syndromes, Cataract
Quality of Life and Visual Acuity of Visglyc Eye Drops on Dry Eye Patients
Clinical trial with medical devices, post-authorization, parallel, single-blind, randomized, comparative, prospective to study how afects the quality of life the use of ocular eye drops on patients with dry eye symptomatology and…
- Trial name
- NCT04063644
- Testing
- Vis Glyc Neo, Physiological saline solution
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- OPKO Health, Inc.
Diabetic Retinopathy
The Effect of Intravitral Injection of Triamcinolone Combined With Cataract Surgery (Phacoemulsification) on Diabetic Macular Edema and Diabetic Retinopathy
In this study, regressed proliferative diabetic retinopathy, very severe, severe and moderate non-prolifrative diabetic retinopathy patients who were going to have a cataract surgery, underwent a complete eye examination, OCT…
- Trial name
- NCT00849537
- Testing
- Triamcinolone
- Where
- 3 sites in Iran
- Sponsor
- Shahid Beheshti University of Medical Sciences
Cataract, Astigmatism
Toric Intraocular Lens Following Cataract Surgery
The objective of this clinical trial is to evaluate the safety and effectiveness of the Bausch + Lomb Toric Accommodating Posterior Chamber Silicone Intraocular Lens used to provide near, intermediate, and distance vision and a…
- Trial name
- NCT01140477
- Testing
- Toric Accommodating Lens, Accommodating Lens
- Where
- United States
- Volunteers
- 229 people
- Sponsor
- Bausch & Lomb Incorporated
Endophthalmitis Following Cataract Surgery
Conjunctival Flora Before Cataract Surgery: a Microbiological Evaluation
The purpose of the present study is to elucidate the qualitative and quantitative variation of ocular flora after treatment with eyedrops containing 0.6% povidone-iodine in the eye of patients undergoing routine cataract surgery.
- Trial name
- NCT03958292
- Testing
- IODIM
- Where
- 6 sites in Italy
- Volunteers
- 140 people
- Sponsor
- Ospedale Sacra Famiglia - Fatebenefratelli Erba
Cataract
Clinical Outcomes With Bilateral Implantation of Odyssey IOLs
This study is a single center, ambispective study of visual outcomes after successful bilateral cataract surgery. Subjects will be assessed at least 3 months postoperatively at a single visit.
- Trial name
- NCT06550375
- Testing
- TECNIS Odyssey IOL
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Mann Eye Institute
Glaucoma, Cataract Senile
Effect of Presbyopic Correction Lens on Humphrey Visual Field Testing in Patients With Multifocal Intraocular Lens
Purpose of this study was to evaluate the effect of presbyopic correction lens on Humphrey visual field (HVF) testing in patients with 2 models of multifocal intraocular lens (MIOL) both with and without glaucoma.
- Trial name
- NCT05220007
- Testing
- Humphrey visual field testing
- Where
- Thailand
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Siriraj Hospital
Cataract
Assessment of Low Energy Lens Fragmentation Cataract Extraction in Patients Undergoing Cataract Surgery
The purpose of this research study is to evaluate the clinical outcomes of the use of low-energy segment removal with a micro-interventional irrigation/aspiration port (MICOR-304) to evacuate the lens prior to intraocular lens…
- Trial name
- NCT04747834
- Testing
- MICOR-304
- Where
- 3 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Carl Zeiss Meditec, Inc.
Refractive Errors
Retrospective Study of the Health Benefits of Ultra-Violet Filtering Contact Lenses
The purpose of this study is to examine the long term effect of ultra-violet filtering contact lenses on macular pigment density (MPOD) and accommodative function.
- Trial name
- NCT01444053
- Testing
- No Intervention
- Where
- United Kingdom
- Volunteers
- 41 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Refractive Errors, Astigmatism
Clinical Assessment of a Daily Wear Monthly Replacement Silicone Hydrogel Toric Contact Lens
The purpose of this clinical study is to assess the clinical performance of an investigational toric soft contact lens compared to a commercially available toric contact lens in a crossover dispense trial when worn in a daily…
- Trial name
- NCT05211739
- Testing
- Lehfilcon A toric contact lenses, Comfilcon A toric contact lenses, CLEAR CARE
- Where
- 7 sites in United States
- Volunteers
- 76 people
- Sponsor
- Alcon Research
Cataract
Refractive Outcomes and Ocular Biometry of Two Swept-Source Optical Coherence Tomography-Based Biometers With Segmental or Equivalent Refractive Indices (ORION)
This prospective, single-centre, randomized, parallel-group comparative clinical study evaluated the refractive prediction accuracy of two swept-source optical coherence tomography (SS-OCT) biometers in a Thai cataract surgery…
- Trial name
- ORION (NCT06377007)
- Testing
- IOLMaster 700 (Carl Zeiss Meditec AG), ARGOS (Movu/Santec; distributed by Alcon)
- Where
- Thailand
- Volunteers
- 144 people
- Sponsor
- Walailak University
Glaucoma, Ocular Hypertension
Safety and Efficacy of TimoD Sustained-Release Implant in Participants With Glaucoma or Ocular Hypertension Undergoing Cataract Surgery
The goal of this clinical trial is to test a new method to deliver an approved medicine called Timolol in the eye of participants with glaucoma or ocular hypertension and requiring cataract surgery.
- Trial name
- NCT07036510
- Testing
- TimoD implant, Injector system, Timolol eye drops 0.5%
- Where
- Panama
- Volunteers
- 42 people
- Sponsor
- EyeD Pharma
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